Details for gene set HALLMARK_IL6_JAK_STAT3

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group1_versus_Group4.MEP.mega_Pheno.cls #Group1_versus_Group4_repos
Phenotype	MEP.mega_Pheno.cls#Group1_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_IL6_JAK_STAT3_SIGNALING
Enrichment Score (ES)	-0.3298679
Normalized Enrichment Score (NES)	-1.1667875
Nominal p-value	0.26337448
FDR q-value	0.59837466
FWER p-Value	0.93

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Il17rb	512	0.601	0.0118	No
2	Jun	632	0.572	0.0422	No
3	Stam2	839	0.525	0.0650	No
4	Tnf	3294	0.282	-0.0445	No
5	Il3ra	3321	0.280	-0.0280	No
6	Pdgfc	3557	0.268	-0.0231	No
7	Hmox1	3717	0.256	-0.0150	No
8	Il6st	3761	0.254	-0.0010	No
9	Csf3r	3973	0.240	0.0034	No
10	Ptpn11	4431	0.219	-0.0063	No
11	Grb2	5162	0.184	-0.0325	No
12	Il4ra	6071	0.136	-0.0710	No
13	Il1r1	6459	0.120	-0.0834	No
14	Il13ra1	6475	0.120	-0.0766	No
15	Il18r1	6710	0.114	-0.0814	No
16	Socs3	7328	0.085	-0.1081	No
17	Pik3r5	7816	0.062	-0.1294	No
18	Dntt	7961	0.055	-0.1334	No
19	Csf1	7978	0.054	-0.1307	No
20	Ptpn2	8134	0.049	-0.1357	No
21	Pim1	8173	0.047	-0.1346	No
22	Itgb3	8367	0.039	-0.1422	No
23	Cd36	8771	0.023	-0.1617	No
24	Ptpn1	8946	0.015	-0.1698	No
25	Stat3	9102	0.008	-0.1773	No
26	Hax1	9492	-0.004	-0.1973	No
27	Il10rb	9802	-0.017	-0.2123	No
28	Tyk2	9919	-0.022	-0.2169	No
29	Il1b	9946	-0.023	-0.2168	No
30	Ccr1	10169	-0.035	-0.2261	No
31	Cd38	10194	-0.036	-0.2250	No
32	Ifnar1	10202	-0.037	-0.2230	No
33	Myd88	10299	-0.041	-0.2254	No
34	Stat1	11045	-0.073	-0.2595	No
35	Cxcl10	11136	-0.077	-0.2593	No
36	Cbl	11217	-0.081	-0.2583	No
37	Cd9	11533	-0.095	-0.2685	No
38	Socs1	11883	-0.111	-0.2796	No
39	Crlf2	11910	-0.112	-0.2737	No
40	Il15ra	12436	-0.133	-0.2925	No
41	Tnfrsf1b	12849	-0.152	-0.3042	No
42	Il7	13011	-0.158	-0.3025	No
43	Itga4	13037	-0.159	-0.2936	No
44	Il17ra	13287	-0.170	-0.2957	No
45	Pf4	13483	-0.178	-0.2944	No
46	Ifngr2	14066	-0.206	-0.3115	No
47	Tnfrsf21	14348	-0.217	-0.3123	Yes
48	Il1r2	14572	-0.229	-0.3092	Yes
49	Cd44	14655	-0.234	-0.2986	Yes
50	Stat2	15246	-0.266	-0.3122	Yes
51	Il12rb1	15586	-0.284	-0.3117	Yes
52	Ebi3	15636	-0.287	-0.2959	Yes
53	Il6	15835	-0.298	-0.2871	Yes
54	Acvr1b	15865	-0.300	-0.2694	Yes
55	Tgfb1	16301	-0.329	-0.2710	Yes
56	Ltbr	16438	-0.339	-0.2564	Yes
57	Tnfrsf1a	16569	-0.348	-0.2409	Yes
58	Map3k8	16801	-0.366	-0.2296	Yes
59	Tnfrsf12a	16835	-0.369	-0.2077	Yes
60	Bak1	17029	-0.384	-0.1932	Yes
61	Ltb	17045	-0.386	-0.1693	Yes
62	Fas	17219	-0.401	-0.1527	Yes
63	Tlr2	17593	-0.433	-0.1444	Yes
64	Irf1	17594	-0.433	-0.1167	Yes
65	Irf9	18194	-0.511	-0.1152	Yes
66	Il2rg	18205	-0.512	-0.0830	Yes
67	Ifngr1	18658	-0.603	-0.0680	Yes
68	Lepr	18824	-0.651	-0.0349	Yes
69	Csf2ra	19227	-0.939	0.0042	Yes