Details for gene set HALLMARK_HEME

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group1_versus_Group4.MEP.mega_Pheno.cls #Group1_versus_Group4_repos
Phenotype	MEP.mega_Pheno.cls#Group1_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_HEME_METABOLISM
Enrichment Score (ES)	-0.34297374
Normalized Enrichment Score (NES)	-1.3176128
Nominal p-value	0.0952381
FDR q-value	0.5449292
FWER p-Value	0.73

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Bmp2k	220	0.726	0.0044	No
2	P4ha2	250	0.707	0.0184	No
3	Igsf3	779	0.536	0.0026	No
4	Osbp2	920	0.511	0.0065	No
5	Acsl6	1111	0.482	0.0071	No
6	Gmps	1401	0.441	0.0017	No
7	Hebp1	1537	0.427	0.0040	No
8	Ncoa4	1795	0.395	-0.0007	No
9	Tent5c	2054	0.371	-0.0061	No
10	Nfe2l1	2225	0.359	-0.0071	No
11	Endod1	2320	0.352	-0.0043	No
12	Mboat2	2362	0.350	0.0012	No
13	Abcg2	2686	0.327	-0.0085	No
14	Trak2	3032	0.301	-0.0199	No
15	Sidt2	3051	0.299	-0.0143	No
16	Dcaf11	3052	0.299	-0.0077	No
17	Fbxo34	3176	0.291	-0.0077	No
18	C3	3420	0.275	-0.0144	No
19	Add2	3477	0.271	-0.0114	No
20	Rnf19a	3564	0.267	-0.0100	No
21	Mpp1	4078	0.235	-0.0317	No
22	Fbxo7	4086	0.234	-0.0269	No
23	Ell2	4127	0.232	-0.0239	No
24	Spta1	4319	0.226	-0.0289	No
25	Mgst3	4324	0.226	-0.0242	No
26	Khnyn	4339	0.225	-0.0200	No
27	Bach1	4494	0.216	-0.0233	No
28	Marchf8	4944	0.192	-0.0426	No
29	Atp6v0a1	5245	0.180	-0.0543	No
30	Ermap	5275	0.178	-0.0519	No
31	Rnf123	5312	0.176	-0.0499	No
32	Gclc	5320	0.175	-0.0465	No
33	Sec14l1	5551	0.163	-0.0549	No
34	Slc6a8	5612	0.160	-0.0545	No
35	Gde1	5686	0.156	-0.0549	No
36	Picalm	5695	0.156	-0.0519	No
37	Smox	5892	0.145	-0.0590	No
38	Map2k3	5964	0.142	-0.0596	No
39	Slc25a38	6169	0.131	-0.0674	No
40	Bnip3l	6602	0.119	-0.0873	No
41	Trim58	6704	0.115	-0.0901	No
42	Abcb6	6713	0.114	-0.0880	No
43	Synj1	6789	0.110	-0.0895	No
44	Ctsb	6794	0.110	-0.0873	No
45	Mospd1	6842	0.108	-0.0874	No
46	Fbxo9	6907	0.105	-0.0884	No
47	Aldh1l1	6934	0.103	-0.0875	No
48	Slc6a9	7170	0.092	-0.0978	No
49	Foxo3	7174	0.092	-0.0959	No
50	Mocos	7252	0.088	-0.0980	No
51	Eif2ak1	7264	0.088	-0.0967	No
52	E2f2	7402	0.081	-0.1021	No
53	Usp15	7475	0.079	-0.1041	No
54	Tns1	7574	0.074	-0.1076	No
55	Clcn3	7633	0.071	-0.1091	No
56	Tfrc	7690	0.069	-0.1105	No
57	Nr3c1	7700	0.068	-0.1095	No
58	Ubac1	7838	0.061	-0.1153	No
59	Ranbp10	7979	0.054	-0.1214	No
60	Gapvd1	8424	0.037	-0.1438	No
61	Aldh6a1	8479	0.034	-0.1459	No
62	Agpat4	8508	0.033	-0.1466	No
63	Rcl1	8551	0.032	-0.1481	No
64	Nek7	8659	0.027	-0.1531	No
65	Hmbs	8702	0.026	-0.1547	No
66	Rbm5	8705	0.026	-0.1543	No
67	Sptb	8777	0.022	-0.1575	No
68	Nudt4	8787	0.022	-0.1575	No
69	Optn	8789	0.022	-0.1571	No
70	Kdm7a	8805	0.021	-0.1574	No
71	Mark3	9140	0.006	-0.1747	No
72	Ppox	9195	0.004	-0.1774	No
73	Cdc27	9234	0.002	-0.1794	No
74	Xpo7	9244	0.002	-0.1798	No
75	Ezh1	9263	0.001	-0.1807	No
76	Asns	9634	-0.009	-0.1999	No
77	Minpp1	9966	-0.024	-0.2166	No
78	Btg2	10015	-0.028	-0.2185	No
79	Epb41	10256	-0.039	-0.2302	No
80	Snca	10258	-0.039	-0.2294	No
81	Tmem9b	10293	-0.040	-0.2303	No
82	Riok3	10371	-0.043	-0.2334	No
83	Slc11a2	10402	-0.044	-0.2340	No
84	Vezf1	10483	-0.048	-0.2371	No
85	Tspan5	10755	-0.060	-0.2500	No
86	Ypel5	10910	-0.067	-0.2565	No
87	Narf	10925	-0.068	-0.2558	No
88	Dcun1d1	10952	-0.069	-0.2556	No
89	Daam1	10960	-0.070	-0.2545	No
90	Nnt	11115	-0.076	-0.2609	No
91	Arhgef12	11339	-0.086	-0.2706	No
92	Dcaf10	11530	-0.095	-0.2785	No
93	Add1	11549	-0.096	-0.2773	No
94	Lpin2	11626	-0.099	-0.2791	No
95	Rhag	11766	-0.106	-0.2841	No
96	Slc30a1	11832	-0.109	-0.2851	No
97	Cast	11862	-0.110	-0.2842	No
98	Ucp2	12117	-0.121	-0.2948	No
99	Pcx	12213	-0.125	-0.2970	No
100	Klf3	12423	-0.133	-0.3050	No
101	Mfhas1	12435	-0.133	-0.3027	No
102	Fech	12538	-0.138	-0.3050	No
103	Foxj2	12635	-0.142	-0.3069	No
104	Slc7a11	12682	-0.144	-0.3061	No
105	Lamp2	12812	-0.150	-0.3096	No
106	Btrc	12850	-0.152	-0.3082	No
107	Blvra	12941	-0.156	-0.3095	No
108	Tcea1	12995	-0.158	-0.3088	No
109	Lmo2	13057	-0.160	-0.3085	No
110	Mxi1	13078	-0.161	-0.3060	No
111	Tnrc6b	13129	-0.163	-0.3050	No
112	Cir1	13198	-0.167	-0.3049	No
113	Epb42	13229	-0.168	-0.3028	No
114	Rbm38	13290	-0.171	-0.3022	No
115	Cpox	13302	-0.171	-0.2990	No
116	Kat2b	13422	-0.175	-0.3014	No
117	Gclm	13478	-0.177	-0.3004	No
118	Pigq	13482	-0.178	-0.2966	No
119	Blvrb	13491	-0.178	-0.2931	No
120	Sdcbp	13519	-0.180	-0.2906	No
121	Psmd9	13548	-0.181	-0.2881	No
122	Atg4a	14140	-0.207	-0.3145	No
123	Top1	14195	-0.209	-0.3127	No
124	Ctns	14775	-0.240	-0.3377	Yes
125	Kel	14856	-0.245	-0.3365	Yes
126	Ackr1	14893	-0.247	-0.3330	Yes
127	Slc4a1	14998	-0.252	-0.3329	Yes
128	Pdzk1ip1	15049	-0.254	-0.3299	Yes
129	Tspo2	15054	-0.255	-0.3245	Yes
130	Mkrn1	15063	-0.255	-0.3193	Yes
131	Urod	15289	-0.269	-0.3252	Yes
132	Myl4	15507	-0.279	-0.3304	Yes
133	Ppp2r5b	15634	-0.287	-0.3307	Yes
134	Ank1	15704	-0.290	-0.3280	Yes
135	Dmtn	15737	-0.292	-0.3232	Yes
136	Slc22a4	15745	-0.293	-0.3172	Yes
137	Gypc	15824	-0.297	-0.3147	Yes
138	Arl2bp	15841	-0.299	-0.3090	Yes
139	Hagh	15891	-0.302	-0.3049	Yes
140	Tmcc2	15911	-0.304	-0.2992	Yes
141	Tal1	16034	-0.313	-0.2988	Yes
142	Htatip2	16048	-0.314	-0.2926	Yes
143	Tfdp2	16065	-0.315	-0.2865	Yes
144	Pgls	16185	-0.322	-0.2856	Yes
145	Car2	16199	-0.323	-0.2792	Yes
146	Acp5	16226	-0.325	-0.2735	Yes
147	Glrx5	16392	-0.336	-0.2747	Yes
148	Xk	16502	-0.344	-0.2729	Yes
149	Cdr2	16556	-0.347	-0.2680	Yes
150	Alad	16568	-0.348	-0.2610	Yes
151	Rap1gap	16757	-0.362	-0.2628	Yes
152	Fn3k	17017	-0.383	-0.2680	Yes
153	Nfe2	17191	-0.398	-0.2683	Yes
154	Icam4	17262	-0.405	-0.2630	Yes
155	Klf1	17518	-0.427	-0.2670	Yes
156	Marchf2	17567	-0.431	-0.2601	Yes
157	Adipor1	17664	-0.439	-0.2555	Yes
158	Lrp10	17812	-0.456	-0.2531	Yes
159	Bpgm	17846	-0.460	-0.2448	Yes
160	Hdgf	17924	-0.471	-0.2384	Yes
161	Slc10a3	18049	-0.490	-0.2342	Yes
162	Epor	18054	-0.490	-0.2236	Yes
163	Gata1	18079	-0.493	-0.2141	Yes
164	Slc66a2	18081	-0.494	-0.2033	Yes
165	H1f0	18090	-0.495	-0.1928	Yes
166	Bsg	18175	-0.508	-0.1861	Yes
167	Selenbp1	18505	-0.568	-0.1908	Yes
168	Rad23a	18616	-0.592	-0.1836	Yes
169	Car1	18699	-0.614	-0.1744	Yes
170	Tyr	18712	-0.616	-0.1615	Yes
171	Htra2	18719	-0.618	-0.1483	Yes
172	Ccnd3	18873	-0.663	-0.1417	Yes
173	Trim10	18882	-0.668	-0.1275	Yes
174	Rhd	18885	-0.668	-0.1129	Yes
175	Ccdc28a	18887	-0.668	-0.0983	Yes
176	Slc2a1	18900	-0.673	-0.0842	Yes
177	Cat	19042	-0.748	-0.0751	Yes
178	Alas2	19066	-0.765	-0.0596	Yes
179	Uros	19202	-0.891	-0.0471	Yes
180	Ctse	19209	-0.897	-0.0277	Yes
181	Prdx2	19306	-1.493	0.0001	Yes