Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group1_versus_Group3.MEP.mega_Pheno.cls #Group1_versus_Group3_repos
Phenotype	MEP.mega_Pheno.cls#Group1_versus_Group3_repos
Upregulated in class	0
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	0.18807931
Normalized Enrichment Score (NES)	0.8369721
Nominal p-value	0.8104839
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	H2ac25	1	1.927	0.0411	Yes
2	Coq8a	29	0.920	0.0594	Yes
3	Ak1	118	0.743	0.0707	Yes
4	Jun	126	0.727	0.0858	Yes
5	Fos	169	0.692	0.0984	Yes
6	Ctsf	278	0.617	0.1060	Yes
7	Il1a	306	0.601	0.1174	Yes
8	Zmat3	372	0.577	0.1264	Yes
9	Tgfa	427	0.563	0.1356	Yes
10	Notch1	471	0.550	0.1451	Yes
11	Rhbdf2	545	0.531	0.1526	Yes
12	Pdgfa	546	0.531	0.1640	Yes
13	Hmox1	613	0.517	0.1716	Yes
14	Slc7a11	866	0.474	0.1685	Yes
15	Stom	951	0.461	0.1740	Yes
16	Dram1	1025	0.447	0.1797	Yes
17	Mdm2	1343	0.409	0.1719	Yes
18	Txnip	1367	0.405	0.1794	Yes
19	Fdxr	1522	0.388	0.1796	Yes
20	Hexim1	1631	0.377	0.1820	Yes
21	Jag2	1669	0.374	0.1881	Yes
22	Zfp365	1819	0.361	0.1880	No
23	Abcc5	2002	0.344	0.1858	No
24	Ccp110	2523	0.307	0.1652	No
25	Cdh13	2609	0.301	0.1672	No
26	Tsc22d1	2732	0.292	0.1671	No
27	Rab40c	2858	0.284	0.1666	No
28	H1f2	2876	0.282	0.1717	No
29	Tob1	3087	0.270	0.1665	No
30	Sat1	3215	0.261	0.1655	No
31	Rchy1	3226	0.261	0.1705	No
32	Kif13b	3367	0.252	0.1686	No
33	Ccnk	3831	0.226	0.1492	No
34	Eps8l2	3864	0.225	0.1523	No
35	Irag2	3883	0.224	0.1562	No
36	Ralgds	3921	0.221	0.1590	No
37	Rnf19b	4073	0.213	0.1556	No
38	Wwp1	4104	0.210	0.1586	No
39	Baiap2	4260	0.201	0.1548	No
40	Aen	4361	0.197	0.1537	No
41	Bmp2	4420	0.194	0.1548	No
42	Mxd1	4459	0.192	0.1570	No
43	Atf3	4553	0.188	0.1561	No
44	Ninj1	4681	0.182	0.1534	No
45	Foxo3	4954	0.170	0.1428	No
46	Plxnb2	4995	0.169	0.1443	No
47	Ddit4	5062	0.166	0.1444	No
48	Gadd45a	5163	0.162	0.1426	No
49	Ada	5237	0.159	0.1422	No
50	Mapkapk3	5370	0.153	0.1386	No
51	Cdkn2aip	5519	0.147	0.1340	No
52	Ei24	5561	0.145	0.1349	No
53	Pcna	5656	0.141	0.1330	No
54	Abat	5669	0.141	0.1354	No
55	Rxra	5707	0.139	0.1365	No
56	Hspa4l	5721	0.138	0.1387	No
57	Rap2b	5749	0.137	0.1403	No
58	Rb1	5765	0.137	0.1424	No
59	Epha2	5781	0.136	0.1445	No
60	Rrp8	5850	0.133	0.1438	No
61	Zbtb16	5865	0.133	0.1459	No
62	Btg1	5933	0.130	0.1452	No
63	Fbxw7	6020	0.127	0.1434	No
64	Sertad3	6047	0.126	0.1447	No
65	Cyfip2	6110	0.123	0.1441	No
66	Plk2	6747	0.101	0.1130	No
67	Dgka	6788	0.099	0.1130	No
68	Perp	6895	0.094	0.1095	No
69	Nudt15	6993	0.090	0.1063	No
70	Csrnp2	7156	0.085	0.0997	No
71	F2r	7195	0.083	0.0995	No
72	Vwa5a	7203	0.083	0.1009	No
73	Pvt1	7424	0.074	0.0909	No
74	Ccnd3	7566	0.068	0.0850	No
75	Trafd1	7632	0.066	0.0830	No
76	Sp1	7773	0.061	0.0770	No
77	Slc35d1	7793	0.060	0.0773	No
78	Apaf1	7808	0.059	0.0778	No
79	Trib3	7987	0.053	0.0696	No
80	Iscu	8015	0.052	0.0693	No
81	Tm7sf3	8041	0.051	0.0691	No
82	Nol8	8048	0.050	0.0699	No
83	Ppm1d	8224	0.044	0.0617	No
84	Mknk2	8606	0.029	0.0424	No
85	Ppp1r15a	8655	0.027	0.0404	No
86	Btg2	8710	0.024	0.0381	No
87	Sphk1	8824	0.020	0.0326	No
88	Tnfsf9	8899	0.018	0.0292	No
89	Blcap	9056	0.012	0.0213	No
90	Sesn1	9072	0.012	0.0207	No
91	H2aj	9129	0.009	0.0180	No
92	Ier5	9279	0.005	0.0103	No
93	Klf4	9565	-0.004	-0.0045	No
94	Ier3	9622	-0.006	-0.0074	No
95	Dnttip2	9802	-0.013	-0.0164	No
96	Prmt2	9803	-0.013	-0.0162	No
97	Fgf13	9902	-0.017	-0.0209	No
98	Tax1bp3	10130	-0.026	-0.0322	No
99	Osgin1	10309	-0.032	-0.0409	No
100	Ephx1	10396	-0.034	-0.0446	No
101	Hbegf	10430	-0.036	-0.0456	No
102	Pom121	10434	-0.036	-0.0450	No
103	Elp1	10472	-0.037	-0.0461	No
104	Fuca1	10550	-0.041	-0.0493	No
105	Polh	10692	-0.046	-0.0556	No
106	Pmm1	10811	-0.051	-0.0607	No
107	Acvr1b	10827	-0.051	-0.0604	No
108	St14	10898	-0.054	-0.0629	No
109	Ercc5	10900	-0.054	-0.0618	No
110	Ip6k2	10920	-0.055	-0.0616	No
111	Ctsd	10937	-0.056	-0.0613	No
112	Mxd4	10993	-0.058	-0.0629	No
113	Slc3a2	11075	-0.061	-0.0659	No
114	Ccnd2	11242	-0.067	-0.0731	No
115	Ddb2	11331	-0.071	-0.0762	No
116	Ccng1	11384	-0.073	-0.0774	No
117	Sfn	11487	-0.078	-0.0810	No
118	Procr	11523	-0.080	-0.0811	No
119	Itgb4	11749	-0.088	-0.0910	No
120	Abhd4	12211	-0.107	-0.1129	No
121	Irak1	12250	-0.109	-0.1125	No
122	Wrap73	12324	-0.112	-0.1139	No
123	Tcn2	12372	-0.114	-0.1140	No
124	App	12395	-0.115	-0.1127	No
125	Bax	12449	-0.117	-0.1129	No
126	Traf4	12697	-0.128	-0.1231	No
127	Ndrg1	13020	-0.143	-0.1369	No
128	Trp53	13037	-0.144	-0.1347	No
129	Fas	13045	-0.145	-0.1319	No
130	Xpc	13318	-0.158	-0.1428	No
131	Fam162a	13574	-0.170	-0.1525	No
132	Tspyl2	13587	-0.171	-0.1495	No
133	Hint1	13594	-0.171	-0.1461	No
134	Ptpre	13726	-0.177	-0.1492	No
135	Socs1	13799	-0.182	-0.1491	No
136	Tgfb1	13841	-0.184	-0.1473	No
137	Hdac3	13989	-0.189	-0.1509	No
138	Cdkn1a	13996	-0.190	-0.1472	No
139	Tpd52l1	14205	-0.201	-0.1537	No
140	Tprkb	14318	-0.206	-0.1552	No
141	Cebpa	14532	-0.216	-0.1617	No
142	Vamp8	14625	-0.222	-0.1618	No
143	Rpl36	14641	-0.223	-0.1578	No
144	Zfp36l1	14776	-0.230	-0.1599	No
145	Def6	14818	-0.233	-0.1570	No
146	Retsat	14882	-0.236	-0.1553	No
147	Rpl18	14946	-0.240	-0.1534	No
148	Sec61a1	15047	-0.245	-0.1534	No
149	Pitpnc1	15253	-0.255	-0.1587	No
150	Triap1	15515	-0.268	-0.1666	No
151	Pidd1	15580	-0.271	-0.1642	No
152	Ankra2	15628	-0.273	-0.1608	No
153	Ddit3	15811	-0.284	-0.1642	No
154	Prkab1	15902	-0.291	-0.1627	No
155	Dcxr	16033	-0.302	-0.1631	No
156	Tap1	16073	-0.304	-0.1586	No
157	Sdc1	16207	-0.314	-0.1589	No
158	Gls2	16223	-0.315	-0.1529	No
159	Vdr	16406	-0.327	-0.1555	No
160	Cd81	16599	-0.344	-0.1581	No
161	Casp1	16812	-0.362	-0.1615	No
162	Rad51c	16958	-0.375	-0.1610	No
163	Slc19a2	17108	-0.388	-0.1605	No
164	S100a10	17133	-0.390	-0.1535	No
165	Klk8	17150	-0.392	-0.1459	No
166	Nupr1	17198	-0.397	-0.1399	No
167	Ptpn14	17292	-0.406	-0.1361	No
168	Rad9a	17391	-0.415	-0.1323	No
169	Steap3	17452	-0.423	-0.1264	No
170	S100a4	17528	-0.430	-0.1212	No
171	Bak1	17676	-0.442	-0.1194	No
172	Plk3	17821	-0.460	-0.1171	No
173	Ifi30	17836	-0.462	-0.1080	No
174	Trp63	17893	-0.467	-0.1009	No
175	Cdk5r1	17912	-0.470	-0.0918	No
176	Rps12	17979	-0.475	-0.0851	No
177	Cgrrf1	18113	-0.492	-0.0815	No
178	Gm2a	18392	-0.539	-0.0846	No
179	Rack1	18465	-0.554	-0.0765	No
180	Upp1	18481	-0.557	-0.0654	No
181	Rrad	18532	-0.571	-0.0558	No
182	Cd82	18549	-0.576	-0.0443	No
183	Phlda3	18754	-0.624	-0.0416	No
184	Cdkn2a	18766	-0.629	-0.0287	No
185	Hras	18832	-0.646	-0.0183	No
186	Ldhb	19250	-0.974	-0.0193	No
187	Rps27l	19266	-1.041	0.0021	No