| Dataset | MEP.MEP.mega_Pheno.cls #Group1_versus_Group3.MEP.mega_Pheno.cls #Group1_versus_Group3_repos |
| Phenotype | MEP.mega_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_MYC_TARGETS_V1 |
| Enrichment Score (ES) | -0.33358756 |
| Normalized Enrichment Score (NES) | -1.1795682 |
| Nominal p-value | 0.3530572 |
| FDR q-value | 0.6753215 |
| FWER p-Value | 0.945 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Hnrnpd | 612 | 0.517 | -0.0195 | No |
| 2 | Gm9531 | 963 | 0.458 | -0.0268 | No |
| 3 | Cdk2 | 1285 | 0.416 | -0.0335 | No |
| 4 | Canx | 1418 | 0.400 | -0.0308 | No |
| 5 | Hnrnpu | 1440 | 0.398 | -0.0223 | No |
| 6 | Hnrnpa2b1 | 1486 | 0.392 | -0.0152 | No |
| 7 | Erh | 1509 | 0.390 | -0.0069 | No |
| 8 | Pgk1 | 1519 | 0.388 | 0.0020 | No |
| 9 | Hnrnpa3 | 1526 | 0.387 | 0.0110 | No |
| 10 | Ifrd1 | 1599 | 0.381 | 0.0164 | No |
| 11 | Prpf31 | 1633 | 0.377 | 0.0238 | No |
| 12 | Kpnb1 | 1673 | 0.374 | 0.0308 | No |
| 13 | Sf3b3 | 1823 | 0.361 | 0.0317 | No |
| 14 | Hdac2 | 1833 | 0.360 | 0.0399 | No |
| 15 | Nolc1 | 2235 | 0.326 | 0.0268 | No |
| 16 | Xpo1 | 2543 | 0.306 | 0.0181 | No |
| 17 | Tfdp1 | 2574 | 0.304 | 0.0239 | No |
| 18 | Hnrnpc | 2801 | 0.287 | 0.0190 | No |
| 19 | Pwp1 | 2957 | 0.276 | 0.0176 | No |
| 20 | Cul1 | 3153 | 0.265 | 0.0138 | No |
| 21 | Hnrnpa1 | 3435 | 0.247 | 0.0050 | No |
| 22 | Mcm7 | 3580 | 0.240 | 0.0033 | No |
| 23 | Xpot | 3848 | 0.226 | -0.0052 | No |
| 24 | Hspd1 | 3976 | 0.218 | -0.0066 | No |
| 25 | Syncrip | 4022 | 0.215 | -0.0038 | No |
| 26 | Exosc7 | 4153 | 0.208 | -0.0056 | No |
| 27 | Psmd1 | 4216 | 0.204 | -0.0039 | No |
| 28 | Odc1 | 4354 | 0.197 | -0.0063 | No |
| 29 | Mcm2 | 4381 | 0.196 | -0.0029 | No |
| 30 | Tardbp | 4394 | 0.195 | 0.0012 | No |
| 31 | Cct5 | 4439 | 0.193 | 0.0035 | No |
| 32 | Acp1 | 4466 | 0.192 | 0.0068 | No |
| 33 | Mcm6 | 4560 | 0.187 | 0.0064 | No |
| 34 | Uba2 | 4686 | 0.182 | 0.0043 | No |
| 35 | Ncbp1 | 4816 | 0.176 | 0.0018 | No |
| 36 | Smarcc1 | 4953 | 0.170 | -0.0012 | No |
| 37 | Cstf2 | 5212 | 0.160 | -0.0109 | No |
| 38 | Xrcc6 | 5292 | 0.157 | -0.0112 | No |
| 39 | Trim28 | 5382 | 0.153 | -0.0122 | No |
| 40 | Srsf1 | 5585 | 0.144 | -0.0193 | No |
| 41 | Pcna | 5656 | 0.141 | -0.0195 | No |
| 42 | Cnbp | 5686 | 0.140 | -0.0177 | No |
| 43 | Mrps18b | 5752 | 0.137 | -0.0178 | No |
| 44 | Rrm1 | 5792 | 0.135 | -0.0165 | No |
| 45 | Cct3 | 5853 | 0.133 | -0.0165 | No |
| 46 | Mcm4 | 5925 | 0.130 | -0.0170 | No |
| 47 | Abce1 | 5957 | 0.129 | -0.0155 | No |
| 48 | Ap3s1 | 6305 | 0.118 | -0.0308 | No |
| 49 | Prps2 | 6339 | 0.117 | -0.0298 | No |
| 50 | Prdx3 | 6620 | 0.105 | -0.0419 | No |
| 51 | Eif3b | 6931 | 0.093 | -0.0558 | No |
| 52 | Snrpa | 6934 | 0.092 | -0.0537 | No |
| 53 | Cdc45 | 6980 | 0.090 | -0.0539 | No |
| 54 | Sf3a1 | 7128 | 0.086 | -0.0595 | No |
| 55 | Srpk1 | 7208 | 0.083 | -0.0617 | No |
| 56 | Nap1l1 | 7412 | 0.074 | -0.0705 | No |
| 57 | Psma2 | 7502 | 0.071 | -0.0734 | No |
| 58 | Dhx15 | 7651 | 0.065 | -0.0796 | No |
| 59 | Tomm70a | 7717 | 0.062 | -0.0815 | No |
| 60 | Pabpc1 | 7719 | 0.062 | -0.0800 | No |
| 61 | Fbl | 7882 | 0.056 | -0.0872 | No |
| 62 | Vdac3 | 8322 | 0.040 | -0.1092 | No |
| 63 | Hnrnpr | 8415 | 0.036 | -0.1131 | No |
| 64 | Nhp2 | 8483 | 0.033 | -0.1158 | No |
| 65 | Mrpl23 | 8599 | 0.029 | -0.1211 | No |
| 66 | Rfc4 | 8760 | 0.022 | -0.1290 | No |
| 67 | Mcm5 | 8791 | 0.021 | -0.1300 | No |
| 68 | Ruvbl2 | 8833 | 0.020 | -0.1317 | No |
| 69 | Ppia | 8951 | 0.016 | -0.1374 | No |
| 70 | Vdac1 | 8956 | 0.016 | -0.1373 | No |
| 71 | Eif4e | 9016 | 0.013 | -0.1400 | No |
| 72 | Eif2s1 | 9162 | 0.008 | -0.1474 | No |
| 73 | Serbp1 | 9185 | 0.007 | -0.1484 | No |
| 74 | Ywhaq | 9295 | 0.004 | -0.1540 | No |
| 75 | Gnl3 | 9303 | 0.004 | -0.1543 | No |
| 76 | Ptges3-ps | 9342 | 0.002 | -0.1562 | No |
| 77 | Tra2b | 9359 | 0.002 | -0.1570 | No |
| 78 | G3bp1 | 9381 | 0.001 | -0.1581 | No |
| 79 | Usp1 | 9389 | 0.001 | -0.1584 | No |
| 80 | Psmc4 | 9474 | -0.000 | -0.1628 | No |
| 81 | Srsf7 | 9592 | -0.005 | -0.1688 | No |
| 82 | Ube2e1 | 9596 | -0.005 | -0.1688 | No |
| 83 | Cct7 | 9716 | -0.010 | -0.1748 | No |
| 84 | Hsp90ab1 | 9742 | -0.011 | -0.1759 | No |
| 85 | Eif4h | 9756 | -0.011 | -0.1763 | No |
| 86 | Psmd8 | 9874 | -0.016 | -0.1820 | No |
| 87 | Snrpd2 | 9895 | -0.017 | -0.1827 | No |
| 88 | Dut | 9939 | -0.019 | -0.1844 | No |
| 89 | Cct4 | 10041 | -0.023 | -0.1892 | No |
| 90 | Ddx21 | 10072 | -0.024 | -0.1902 | No |
| 91 | Ppm1g | 10080 | -0.024 | -0.1899 | No |
| 92 | Eif4a1 | 10162 | -0.027 | -0.1935 | No |
| 93 | Etf1 | 10538 | -0.041 | -0.2122 | No |
| 94 | Apex1 | 10541 | -0.041 | -0.2113 | No |
| 95 | Eif4g2 | 10544 | -0.041 | -0.2104 | No |
| 96 | Nme1 | 10546 | -0.041 | -0.2095 | No |
| 97 | Rps6 | 10682 | -0.046 | -0.2154 | No |
| 98 | Rad23b | 10699 | -0.046 | -0.2151 | No |
| 99 | Eif3j1 | 10831 | -0.051 | -0.2207 | No |
| 100 | Cad | 10852 | -0.053 | -0.2205 | No |
| 101 | Tcp1 | 10908 | -0.055 | -0.2221 | No |
| 102 | Fam120a | 11169 | -0.065 | -0.2341 | No |
| 103 | Psmc6 | 11255 | -0.068 | -0.2369 | No |
| 104 | Gspt1 | 11287 | -0.069 | -0.2369 | No |
| 105 | Pold2 | 11300 | -0.069 | -0.2359 | No |
| 106 | Orc2 | 11324 | -0.070 | -0.2354 | No |
| 107 | Txnl4a | 11437 | -0.076 | -0.2394 | No |
| 108 | Nop56 | 11620 | -0.083 | -0.2469 | No |
| 109 | Srsf2 | 11623 | -0.083 | -0.2450 | No |
| 110 | Stard7 | 11963 | -0.097 | -0.2604 | No |
| 111 | Cct2 | 12026 | -0.100 | -0.2612 | No |
| 112 | Cbx3 | 12245 | -0.109 | -0.2700 | No |
| 113 | Eef1b2 | 12333 | -0.112 | -0.2719 | No |
| 114 | Srm | 12823 | -0.134 | -0.2942 | No |
| 115 | Snrpd1 | 12842 | -0.135 | -0.2919 | No |
| 116 | Impdh2 | 12869 | -0.136 | -0.2900 | No |
| 117 | Ilf2 | 13140 | -0.148 | -0.3005 | No |
| 118 | Psmd3 | 13211 | -0.152 | -0.3005 | No |
| 119 | Rnps1 | 13363 | -0.160 | -0.3045 | No |
| 120 | Psma4 | 13690 | -0.176 | -0.3174 | No |
| 121 | Eif3d | 13825 | -0.183 | -0.3200 | No |
| 122 | Psmd14 | 13963 | -0.189 | -0.3226 | No |
| 123 | Clns1a | 14064 | -0.195 | -0.3231 | No |
| 124 | Snrpd3 | 14182 | -0.199 | -0.3244 | No |
| 125 | Ywhae | 14291 | -0.205 | -0.3251 | No |
| 126 | Dek | 14400 | -0.211 | -0.3257 | No |
| 127 | Ranbp1 | 14420 | -0.212 | -0.3216 | No |
| 128 | Rsl1d1 | 14647 | -0.224 | -0.3280 | No |
| 129 | Rrp9 | 14755 | -0.229 | -0.3281 | Yes |
| 130 | Srsf3 | 14764 | -0.230 | -0.3229 | Yes |
| 131 | Cox5a | 14870 | -0.235 | -0.3228 | Yes |
| 132 | Ldha | 14926 | -0.238 | -0.3199 | Yes |
| 133 | Ddx18 | 14933 | -0.239 | -0.3144 | Yes |
| 134 | Rpl18 | 14946 | -0.240 | -0.3093 | Yes |
| 135 | Rps2 | 14972 | -0.242 | -0.3048 | Yes |
| 136 | Psmb3 | 14981 | -0.242 | -0.2993 | Yes |
| 137 | Rpl22 | 15245 | -0.254 | -0.3070 | Yes |
| 138 | Ncbp2 | 15321 | -0.258 | -0.3047 | Yes |
| 139 | Ndufab1 | 15428 | -0.264 | -0.3038 | Yes |
| 140 | Tufm | 15602 | -0.272 | -0.3063 | Yes |
| 141 | Psmd7 | 15608 | -0.272 | -0.3000 | Yes |
| 142 | Snrpa1 | 15633 | -0.274 | -0.2947 | Yes |
| 143 | Pa2g4 | 15660 | -0.275 | -0.2894 | Yes |
| 144 | H2az1 | 15862 | -0.288 | -0.2930 | Yes |
| 145 | Eif2s2 | 15864 | -0.288 | -0.2861 | Yes |
| 146 | Psma6 | 15903 | -0.291 | -0.2810 | Yes |
| 147 | Npm1 | 16166 | -0.310 | -0.2873 | Yes |
| 148 | Rplp0 | 16178 | -0.311 | -0.2803 | Yes |
| 149 | Cops5 | 16200 | -0.313 | -0.2739 | Yes |
| 150 | Hspe1 | 16218 | -0.314 | -0.2672 | Yes |
| 151 | Ssb | 16344 | -0.323 | -0.2659 | Yes |
| 152 | Hddc2 | 16431 | -0.329 | -0.2625 | Yes |
| 153 | Tyms | 16573 | -0.342 | -0.2616 | Yes |
| 154 | Ssbp1 | 16606 | -0.345 | -0.2550 | Yes |
| 155 | Psma7 | 16639 | -0.348 | -0.2483 | Yes |
| 156 | Got2 | 16692 | -0.353 | -0.2425 | Yes |
| 157 | Cdk4 | 16700 | -0.354 | -0.2343 | Yes |
| 158 | Prdx4 | 16744 | -0.357 | -0.2279 | Yes |
| 159 | Pole3 | 16772 | -0.359 | -0.2207 | Yes |
| 160 | Hdgf | 16818 | -0.363 | -0.2143 | Yes |
| 161 | Cyc1 | 16850 | -0.366 | -0.2071 | Yes |
| 162 | Vbp1 | 16883 | -0.368 | -0.1999 | Yes |
| 163 | Rpl14 | 16996 | -0.379 | -0.1966 | Yes |
| 164 | Mrpl9 | 17002 | -0.379 | -0.1877 | Yes |
| 165 | Pabpc4 | 17224 | -0.398 | -0.1897 | Yes |
| 166 | Mad2l1 | 17230 | -0.399 | -0.1803 | Yes |
| 167 | Psma1 | 17398 | -0.416 | -0.1790 | Yes |
| 168 | Rps3 | 17425 | -0.419 | -0.1702 | Yes |
| 169 | Rpl6 | 17590 | -0.434 | -0.1684 | Yes |
| 170 | Ccna2 | 17717 | -0.447 | -0.1642 | Yes |
| 171 | Slc25a3 | 17776 | -0.453 | -0.1563 | Yes |
| 172 | Rps5 | 17797 | -0.457 | -0.1463 | Yes |
| 173 | Snrpb2 | 17825 | -0.460 | -0.1366 | Yes |
| 174 | C1qbp | 18040 | -0.482 | -0.1362 | Yes |
| 175 | Ran | 18123 | -0.493 | -0.1286 | Yes |
| 176 | Snrpg | 18171 | -0.501 | -0.1189 | Yes |
| 177 | Rps10 | 18193 | -0.504 | -0.1079 | Yes |
| 178 | Myc | 18210 | -0.506 | -0.0965 | Yes |
| 179 | Bub3 | 18259 | -0.515 | -0.0866 | Yes |
| 180 | Psmb2 | 18348 | -0.529 | -0.0784 | Yes |
| 181 | Rack1 | 18465 | -0.554 | -0.0711 | Yes |
| 182 | Pcbp1 | 18499 | -0.561 | -0.0593 | Yes |
| 183 | Lsm2 | 18603 | -0.588 | -0.0505 | Yes |
| 184 | Glo1 | 18642 | -0.594 | -0.0382 | Yes |
| 185 | Nop16 | 18810 | -0.640 | -0.0315 | Yes |
| 186 | Phb2 | 18814 | -0.641 | -0.0162 | Yes |
| 187 | Aimp2 | 19108 | -0.781 | -0.0127 | Yes |
| 188 | Cdc20 | 19245 | -0.955 | 0.0032 | Yes |

