Details for gene set HALLMARK_E2F

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group1_versus_Group3.MEP.mega_Pheno.cls #Group1_versus_Group3_repos
Phenotype	MEP.mega_Pheno.cls#Group1_versus_Group3_repos
Upregulated in class	2
GeneSet	HALLMARK_E2F_TARGETS
Enrichment Score (ES)	-0.31445345
Normalized Enrichment Score (NES)	-1.188292
Nominal p-value	0.30309278
FDR q-value	0.70526105
FWER p-Value	0.937

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Hnrnpd	612	0.517	-0.0198	No
2	Donson	787	0.485	-0.0174	No
3	Dck	1133	0.432	-0.0253	No
4	Pnn	1619	0.379	-0.0417	No
5	Smc3	1620	0.379	-0.0327	No
6	Nasp	1714	0.369	-0.0288	No
7	Mre11a	1754	0.366	-0.0222	No
8	Mlh1	1757	0.366	-0.0137	No
9	Nolc1	2235	0.326	-0.0309	No
10	Ccp110	2523	0.307	-0.0387	No
11	Xpo1	2543	0.306	-0.0324	No
12	Atad2	2626	0.300	-0.0296	No
13	Ipo7	2719	0.293	-0.0275	No
14	Anp32e	2729	0.292	-0.0210	No
15	Zw10	2809	0.287	-0.0184	No
16	Dnmt1	2998	0.275	-0.0217	No
17	Brms1l	2999	0.275	-0.0152	No
18	Rpa1	3011	0.274	-0.0093	No
19	Ilf3	3507	0.244	-0.0295	No
20	Mcm7	3580	0.240	-0.0276	No
21	Cse1l	3824	0.227	-0.0349	No
22	Syncrip	4022	0.215	-0.0401	No
23	Brca1	4297	0.200	-0.0497	No
24	Lbr	4342	0.198	-0.0473	No
25	Mcm2	4381	0.196	-0.0447	No
26	Pold3	4403	0.195	-0.0412	No
27	Mcm6	4560	0.187	-0.0449	No
28	Suv39h1	4642	0.185	-0.0448	No
29	Gins3	4935	0.171	-0.0560	No
30	Nudt21	4955	0.170	-0.0530	No
31	Mcm3	5017	0.167	-0.0522	No
32	Msh2	5095	0.165	-0.0524	No
33	Prkdc	5206	0.160	-0.0543	No
34	Cdkn1b	5250	0.159	-0.0528	No
35	Phf5a	5253	0.159	-0.0492	No
36	Xrcc6	5292	0.157	-0.0474	No
37	Brca2	5294	0.157	-0.0438	No
38	Chek1	5319	0.156	-0.0413	No
39	Nbn	5326	0.156	-0.0380	No
40	Lmnb1	5558	0.146	-0.0466	No
41	Srsf1	5585	0.144	-0.0446	No
42	Pcna	5656	0.141	-0.0449	No
43	Lig1	5689	0.140	-0.0433	No
44	Prim2	5709	0.139	-0.0410	No
45	Cdc25a	5902	0.131	-0.0479	No
46	Mcm4	5925	0.130	-0.0460	No
47	Smc6	5989	0.128	-0.0463	No
48	Slbp	6044	0.126	-0.0461	No
49	Nup107	6065	0.125	-0.0442	No
50	Rad21	6181	0.120	-0.0474	No
51	Wee1	6550	0.108	-0.0641	No
52	Mybl2	6564	0.108	-0.0622	No
53	Orc6	6655	0.104	-0.0645	No
54	Shmt1	7266	0.081	-0.0945	No
55	Nap1l1	7412	0.074	-0.1003	No
56	Wdr90	7453	0.073	-0.1007	No
57	Smc1a	7485	0.071	-0.1006	No
58	Tfrc	7686	0.063	-0.1096	No
59	Hus1	7720	0.062	-0.1098	No
60	Luc7l3	7821	0.059	-0.1137	No
61	Pds5b	7910	0.055	-0.1170	No
62	Eed	8057	0.050	-0.1234	No
63	Pole	8099	0.049	-0.1244	No
64	Nup153	8119	0.048	-0.1243	No
65	E2f8	8124	0.048	-0.1234	No
66	Ppm1d	8224	0.044	-0.1275	No
67	Rfc1	8306	0.040	-0.1308	No
68	Ezh2	8667	0.026	-0.1490	No
69	Mcm5	8791	0.021	-0.1550	No
70	Ddx39a	8826	0.020	-0.1563	No
71	Rbbp7	8880	0.018	-0.1586	No
72	Dlgap5	8938	0.016	-0.1612	No
73	Cdc25b	8964	0.015	-0.1622	No
74	Stag1	9140	0.009	-0.1711	No
75	Eif2s1	9162	0.008	-0.1720	No
76	Tra2b	9359	0.002	-0.1822	No
77	Usp1	9389	0.001	-0.1837	No
78	Tbrg4	9754	-0.011	-0.2025	No
79	Rad51ap1	9786	-0.012	-0.2038	No
80	Timeless	9792	-0.013	-0.2038	No
81	Bub1b	9833	-0.014	-0.2055	No
82	Dut	9939	-0.019	-0.2106	No
83	Cbx5	9991	-0.021	-0.2128	No
84	Ubr7	10113	-0.026	-0.2185	No
85	Cit	10180	-0.028	-0.2213	No
86	Rpa2	10202	-0.028	-0.2217	No
87	Pola2	10212	-0.028	-0.2215	No
88	Pan2	10218	-0.028	-0.2211	No
89	Jpt1	10307	-0.031	-0.2250	No
90	Nme1	10546	-0.041	-0.2365	No
91	Cnot9	10551	-0.041	-0.2357	No
92	Nup205	10589	-0.042	-0.2366	No
93	Kif22	10663	-0.045	-0.2394	No
94	Dscc1	10759	-0.049	-0.2432	No
95	Rnaseh2a	10886	-0.054	-0.2485	No
96	Tmpo	10934	-0.056	-0.2497	No
97	Tcf19	11002	-0.058	-0.2518	No
98	Ncapd2	11053	-0.060	-0.2530	No
99	Cdca8	11074	-0.061	-0.2526	No
100	Gspt1	11287	-0.069	-0.2621	No
101	Pold2	11300	-0.069	-0.2611	No
102	Orc2	11324	-0.070	-0.2606	No
103	Psmc3ip	11591	-0.082	-0.2726	No
104	Ube2t	11609	-0.082	-0.2715	No
105	Nop56	11620	-0.083	-0.2701	No
106	Srsf2	11623	-0.083	-0.2682	No
107	Chek2	11708	-0.086	-0.2706	No
108	Ak2	11794	-0.090	-0.2729	No
109	Top2a	11858	-0.092	-0.2741	No
110	Mms22l	11870	-0.092	-0.2724	No
111	Pold1	11918	-0.095	-0.2727	No
112	Hells	12055	-0.100	-0.2774	No
113	Hmgb3	12264	-0.109	-0.2857	No
114	Psip1	12414	-0.116	-0.2908	No
115	Aurka	12437	-0.117	-0.2892	No
116	Ung	12468	-0.118	-0.2879	No
117	Tk1	12520	-0.120	-0.2877	No
118	Rad50	12907	-0.138	-0.3047	No
119	Ssrp1	12908	-0.138	-0.3014	No
120	Diaph3	12913	-0.138	-0.2984	No
121	Trp53	13037	-0.144	-0.3014	No
122	Dclre1b	13159	-0.149	-0.3042	No
123	Ppp1r8	13356	-0.160	-0.3107	Yes
124	Espl1	13368	-0.160	-0.3075	Yes
125	Cdk1	13427	-0.164	-0.3066	Yes
126	Aurkb	13436	-0.164	-0.3031	Yes
127	Depdc1a	13517	-0.167	-0.3034	Yes
128	Racgap1	13667	-0.175	-0.3071	Yes
129	Tipin	13687	-0.175	-0.3039	Yes
130	Ing3	13721	-0.177	-0.3014	Yes
131	Ccne1	13860	-0.185	-0.3043	Yes
132	Melk	13927	-0.188	-0.3033	Yes
133	Paics	13991	-0.190	-0.3021	Yes
134	Cdkn1a	13996	-0.190	-0.2978	Yes
135	Trip13	14104	-0.196	-0.2988	Yes
136	Plk4	14110	-0.196	-0.2944	Yes
137	Rad1	14305	-0.206	-0.2997	Yes
138	Dek	14400	-0.211	-0.2996	Yes
139	Tacc3	14407	-0.211	-0.2949	Yes
140	Ranbp1	14420	-0.212	-0.2905	Yes
141	Lsm8	14430	-0.212	-0.2860	Yes
142	Snrpb	14463	-0.214	-0.2826	Yes
143	Exosc8	14476	-0.214	-0.2781	Yes
144	Plk1	14576	-0.219	-0.2781	Yes
145	Spag5	14707	-0.228	-0.2796	Yes
146	Smc4	14783	-0.231	-0.2780	Yes
147	Ctcf	14967	-0.241	-0.2819	Yes
148	Kif4	14975	-0.242	-0.2765	Yes
149	Bard1	15132	-0.248	-0.2788	Yes
150	Mxd3	15150	-0.248	-0.2739	Yes
151	Pop7	15153	-0.249	-0.2681	Yes
152	Gins4	15180	-0.250	-0.2635	Yes
153	Kif2c	15196	-0.251	-0.2584	Yes
154	Spc24	15411	-0.263	-0.2634	Yes
155	Cdkn2c	15584	-0.271	-0.2659	Yes
156	Pa2g4	15660	-0.275	-0.2634	Yes
157	Stmn1	15743	-0.281	-0.2610	Yes
158	H2az1	15862	-0.288	-0.2604	Yes
159	Mthfd2	15875	-0.289	-0.2542	Yes
160	Lyar	16127	-0.308	-0.2600	Yes
161	Spc25	16212	-0.314	-0.2570	Yes
162	Rfc2	16237	-0.316	-0.2508	Yes
163	Rpa3	16349	-0.323	-0.2489	Yes
164	Hmmr	16392	-0.326	-0.2434	Yes
165	Birc5	16430	-0.329	-0.2376	Yes
166	Cdk4	16700	-0.354	-0.2433	Yes
167	Prdx4	16744	-0.357	-0.2371	Yes
168	Mki67	16771	-0.359	-0.2300	Yes
169	Pole4	16823	-0.363	-0.2240	Yes
170	Hmgb2	16896	-0.370	-0.2191	Yes
171	Rad51c	16958	-0.375	-0.2134	Yes
172	Tubb5	16970	-0.376	-0.2050	Yes
173	Asf1a	17169	-0.394	-0.2061	Yes
174	Pms2	17179	-0.395	-0.1972	Yes
175	Mad2l1	17230	-0.399	-0.1904	Yes
176	Cenpe	17252	-0.401	-0.1820	Yes
177	Pttg1	17277	-0.404	-0.1737	Yes
178	Ccnb2	17343	-0.411	-0.1674	Yes
179	Gins1	17524	-0.429	-0.1667	Yes
180	Rfc3	17563	-0.432	-0.1584	Yes
181	Cks2	17605	-0.436	-0.1503	Yes
182	Dctpp1	17653	-0.441	-0.1423	Yes
183	H2ax	17684	-0.442	-0.1334	Yes
184	Ube2s	17738	-0.449	-0.1256	Yes
185	Cdkn3	18032	-0.481	-0.1295	Yes
186	Ran	18123	-0.493	-0.1226	Yes
187	Rrm2	18153	-0.498	-0.1123	Yes
188	Myc	18210	-0.506	-0.1033	Yes
189	Tubg1	18339	-0.527	-0.0975	Yes
190	Asf1b	18351	-0.529	-0.0856	Yes
191	Prps1	18474	-0.556	-0.0788	Yes
192	Kif18b	18718	-0.611	-0.0771	Yes
193	Cdkn2a	18766	-0.629	-0.0646	Yes
194	Cdca3	18813	-0.641	-0.0519	Yes
195	Cenpm	18958	-0.699	-0.0429	Yes
196	Cks1b	19026	-0.725	-0.0292	Yes
197	Hmga1b	19201	-0.897	-0.0171	Yes
198	Cdc20	19245	-0.955	0.0032	Yes