Details for gene set HALLMARK_TNFA_SIGNALING_VIA

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group1_versus_Group2.MEP.mega_Pheno.cls #Group1_versus_Group2_repos
Phenotype	MEP.mega_Pheno.cls#Group1_versus_Group2_repos
Upregulated in class	1
GeneSet	HALLMARK_TNFA_SIGNALING_VIA_NFKB
Enrichment Score (ES)	-0.2578975
Normalized Enrichment Score (NES)	-0.9885482
Nominal p-value	0.4621514
FDR q-value	0.96273905
FWER p-Value	0.985

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Dram1	293	0.643	0.0022	No
2	Plau	370	0.611	0.0148	No
3	Ier2	401	0.596	0.0295	No
4	Zc3h12a	495	0.567	0.0400	No
5	Tnf	533	0.557	0.0532	No
6	Ccnd1	620	0.533	0.0632	No
7	Nr4a1	894	0.480	0.0620	No
8	Cebpb	973	0.467	0.0707	No
9	Hes1	1512	0.396	0.0533	No
10	Bcl6	1544	0.392	0.0624	No
11	Tgif1	1806	0.368	0.0588	No
12	Fosl2	1871	0.362	0.0652	No
13	Marcks	1929	0.356	0.0720	No
14	Trib1	2076	0.342	0.0736	No
15	Hbegf	2396	0.318	0.0656	No
16	Gem	2398	0.317	0.0742	No
17	Clcf1	2438	0.314	0.0807	No
18	Dusp2	2642	0.302	0.0783	No
19	Tnip1	2693	0.298	0.0838	No
20	B4galt5	2949	0.281	0.0781	No
21	Fosl1	3283	0.260	0.0678	No
22	Cxcl10	3511	0.246	0.0627	No
23	Sphk1	3514	0.246	0.0693	No
24	Klf10	3524	0.246	0.0755	No
25	Ppp1r15a	3669	0.237	0.0744	No
26	Plek	3740	0.233	0.0771	No
27	Zbtb10	4149	0.211	0.0615	No
28	Egr1	4298	0.204	0.0593	No
29	Litaf	4423	0.198	0.0582	No
30	Sod2	4628	0.188	0.0527	No
31	Yrdc	4883	0.176	0.0442	No
32	Ptger4	4959	0.173	0.0450	No
33	Smad3	5048	0.168	0.0450	No
34	Olr1	5153	0.163	0.0440	No
35	Plpp3	5156	0.163	0.0483	No
36	Dusp1	5219	0.160	0.0494	No
37	Jag1	5274	0.158	0.0509	No
38	Ptpre	5593	0.144	0.0382	No
39	Lamb3	5712	0.139	0.0358	No
40	Ripk2	5928	0.130	0.0281	No
41	Ccl5	5978	0.128	0.0290	No
42	Ifit2	6136	0.122	0.0241	No
43	Fos	6145	0.122	0.0270	No
44	Btg1	6285	0.117	0.0229	No
45	Panx1	6310	0.117	0.0249	No
46	Tnfsf9	6457	0.110	0.0202	No
47	Il7r	6577	0.105	0.0169	No
48	Klf4	6662	0.102	0.0153	No
49	Pnrc1	6731	0.100	0.0144	No
50	Gadd45a	6987	0.090	0.0036	No
51	Cxcl5	7004	0.090	0.0052	No
52	Zfp36	7012	0.089	0.0072	No
53	Jun	7239	0.081	-0.0024	No
54	Rel	7254	0.080	-0.0009	No
55	Rcan1	7342	0.077	-0.0034	No
56	Trip10	7409	0.074	-0.0048	No
57	Nr4a2	7556	0.070	-0.0105	No
58	Il18	7569	0.069	-0.0093	No
59	Pfkfb3	7608	0.068	-0.0094	No
60	Relb	7652	0.067	-0.0099	No
61	Ccnl1	7762	0.063	-0.0138	No
62	Tnfaip2	7775	0.062	-0.0128	No
63	Fjx1	7829	0.060	-0.0139	No
64	Ccrl2	8060	0.052	-0.0245	No
65	Spsb1	8071	0.051	-0.0237	No
66	Icosl	8185	0.048	-0.0283	No
67	Atp2b1	8260	0.045	-0.0309	No
68	Id2	8264	0.045	-0.0299	No
69	Rela	8360	0.042	-0.0337	No
70	Cdkn1a	8434	0.040	-0.0364	No
71	Gfpt2	8458	0.039	-0.0365	No
72	Ier3	8467	0.039	-0.0359	No
73	Rigi	8520	0.037	-0.0376	No
74	Serpinb2	8609	0.035	-0.0412	No
75	Dusp5	9289	0.011	-0.0764	No
76	Pde4b	9321	0.010	-0.0778	No
77	Tsc22d1	9423	0.007	-0.0829	No
78	Cflar	9494	0.005	-0.0864	No
79	Serpinb8	9531	0.003	-0.0882	No
80	Nfkb2	9571	0.002	-0.0902	No
81	Tap1	9806	-0.005	-0.1023	No
82	Ldlr	9959	-0.011	-0.1099	No
83	Nfat5	10081	-0.014	-0.1158	No
84	Cd80	10128	-0.016	-0.1178	No
85	Phlda1	10218	-0.019	-0.1219	No
86	Irs2	10261	-0.021	-0.1236	No
87	Dennd5a	10416	-0.026	-0.1309	No
88	Rhob	10460	-0.027	-0.1324	No
89	Tubb2a	10545	-0.030	-0.1360	No
90	Map3k8	10577	-0.031	-0.1368	No
91	B4galt1	10613	-0.032	-0.1377	No
92	Ehd1	10770	-0.037	-0.1448	No
93	Slc16a6	10988	-0.044	-0.1550	No
94	Tnfaip8	11216	-0.052	-0.1654	No
95	Birc2	11228	-0.053	-0.1645	No
96	Birc3	11348	-0.057	-0.1692	No
97	Ets2	11370	-0.058	-0.1687	No
98	Pdlim5	11433	-0.061	-0.1703	No
99	Socs3	11463	-0.062	-0.1702	No
100	Stat5a	12020	-0.083	-0.1970	No
101	Csf1	12129	-0.087	-0.2002	No
102	Tiparp	12217	-0.090	-0.2023	No
103	Klf2	12295	-0.092	-0.2039	No
104	Map2k3	12468	-0.098	-0.2102	No
105	Il15ra	12622	-0.105	-0.2153	No
106	Per1	12720	-0.109	-0.2174	No
107	Cd44	12726	-0.109	-0.2147	No
108	Ifih1	12791	-0.111	-0.2150	No
109	Atf3	12989	-0.119	-0.2221	No
110	Nampt	13224	-0.126	-0.2309	No
111	Nfkbie	13268	-0.128	-0.2296	No
112	Plk2	13542	-0.139	-0.2401	No
113	Tnfrsf9	13580	-0.140	-0.2383	No
114	Rnf19b	13934	-0.156	-0.2524	No
115	Egr3	14038	-0.161	-0.2535	Yes
116	Mcl1	14124	-0.163	-0.2535	Yes
117	Nfil3	14126	-0.163	-0.2491	Yes
118	Nfe2l2	14246	-0.169	-0.2507	Yes
119	Fut4	14254	-0.170	-0.2464	Yes
120	Kdm6b	14261	-0.170	-0.2421	Yes
121	Ifngr2	14296	-0.171	-0.2392	Yes
122	Il1a	14376	-0.176	-0.2386	Yes
123	Fosb	14426	-0.177	-0.2363	Yes
124	Dnajb4	14430	-0.177	-0.2316	Yes
125	Tank	14518	-0.182	-0.2313	Yes
126	Sat1	14716	-0.190	-0.2364	Yes
127	Gch1	14855	-0.196	-0.2383	Yes
128	Tnip2	14933	-0.201	-0.2368	Yes
129	Eif1	14942	-0.201	-0.2318	Yes
130	Btg3	15259	-0.217	-0.2424	Yes
131	Pmepa1	15319	-0.220	-0.2395	Yes
132	Cebpd	15460	-0.228	-0.2406	Yes
133	Sgk1	15513	-0.230	-0.2370	Yes
134	Btg2	15551	-0.232	-0.2327	Yes
135	Nfkb1	15723	-0.242	-0.2350	Yes
136	Bmp2	15845	-0.247	-0.2346	Yes
137	Maff	15859	-0.248	-0.2285	Yes
138	Myc	15993	-0.257	-0.2285	Yes
139	Mxd1	16060	-0.262	-0.2248	Yes
140	Vegfa	16093	-0.264	-0.2193	Yes
141	Junb	16128	-0.266	-0.2138	Yes
142	Nfkbia	16280	-0.275	-0.2142	Yes
143	Bhlhe40	16341	-0.279	-0.2098	Yes
144	Slc2a3	16419	-0.284	-0.2061	Yes
145	Il6st	17027	-0.328	-0.2289	Yes
146	Tlr2	17030	-0.328	-0.2200	Yes
147	Ninj1	17071	-0.332	-0.2131	Yes
148	Kynu	17150	-0.338	-0.2080	Yes
149	Snn	17186	-0.342	-0.2005	Yes
150	Klf9	17517	-0.368	-0.2077	Yes
151	Abca1	17531	-0.369	-0.1984	Yes
152	Gadd45b	17641	-0.380	-0.1937	Yes
153	Nr4a3	17708	-0.387	-0.1866	Yes
154	Slc2a6	17723	-0.389	-0.1768	Yes
155	Ier5	18108	-0.428	-0.1852	Yes
156	Irf1	18157	-0.434	-0.1759	Yes
157	Tnfaip3	18481	-0.480	-0.1797	Yes
158	Klf6	18487	-0.482	-0.1669	Yes
159	Icam1	18721	-0.534	-0.1645	Yes
160	Dusp4	18722	-0.535	-0.1500	Yes
161	Gpr183	18771	-0.545	-0.1377	Yes
162	Bcl3	18920	-0.589	-0.1294	Yes
163	Phlda2	18943	-0.595	-0.1143	Yes
164	Sqstm1	18967	-0.605	-0.0991	Yes
165	Cd69	19181	-0.739	-0.0901	Yes
166	Il1b	19189	-0.746	-0.0702	Yes
167	Il6	19208	-0.767	-0.0503	Yes
168	Traf1	19235	-0.805	-0.0297	Yes
169	Plaur	19303	-1.228	0.0002	Yes