Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | MEP.MEP.mega_Pheno.cls #Group1_versus_Group2.MEP.mega_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | MEP.mega_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_TGF_BETA_SIGNALING |
| Enrichment Score (ES) | -0.23279706 |
| Normalized Enrichment Score (NES) | -0.97840726 |
| Nominal p-value | 0.515873 |
| FDR q-value | 0.9331706 |
| FWER p-Value | 0.986 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cdh1 | 250 | 0.661 | 0.0474 | No |
| 2 | Ncor2 | 260 | 0.657 | 0.1069 | No |
| 3 | Bmpr1a | 1104 | 0.449 | 0.1041 | No |
| 4 | Tgif1 | 1806 | 0.368 | 0.1013 | No |
| 5 | Wwtr1 | 1920 | 0.357 | 0.1281 | No |
| 6 | Cdkn1c | 2083 | 0.342 | 0.1509 | No |
| 7 | Klf10 | 3524 | 0.246 | 0.0986 | No |
| 8 | Ppp1r15a | 3669 | 0.237 | 0.1127 | No |
| 9 | Furin | 4055 | 0.216 | 0.1125 | No |
| 10 | Ctnnb1 | 4294 | 0.204 | 0.1188 | No |
| 11 | Hipk2 | 4374 | 0.200 | 0.1330 | No |
| 12 | Eng | 4909 | 0.175 | 0.1212 | No |
| 13 | Tgfbr1 | 4958 | 0.173 | 0.1345 | No |
| 14 | Smad3 | 5048 | 0.168 | 0.1452 | No |
| 15 | Sptbn1 | 5752 | 0.138 | 0.1213 | No |
| 16 | Ppm1a | 5897 | 0.132 | 0.1258 | No |
| 17 | Cdk9 | 5898 | 0.131 | 0.1378 | No |
| 18 | Trim33 | 6399 | 0.113 | 0.1222 | No |
| 19 | Id2 | 8264 | 0.045 | 0.0295 | No |
| 20 | Slc20a1 | 8660 | 0.033 | 0.0120 | No |
| 21 | Map3k7 | 8755 | 0.030 | 0.0098 | No |
| 22 | Fnta | 8850 | 0.026 | 0.0073 | No |
| 23 | Hdac1 | 9516 | 0.004 | -0.0269 | No |
| 24 | Tgfb1 | 9845 | -0.006 | -0.0434 | No |
| 25 | Ube2d3 | 9884 | -0.007 | -0.0447 | No |
| 26 | Ppp1ca | 10059 | -0.013 | -0.0525 | No |
| 27 | Xiap | 10244 | -0.020 | -0.0602 | No |
| 28 | Thbs1 | 12047 | -0.084 | -0.1461 | No |
| 29 | Bcar3 | 12306 | -0.092 | -0.1511 | No |
| 30 | Bmpr2 | 13881 | -0.154 | -0.2188 | Yes |
| 31 | Ltbp2 | 14102 | -0.163 | -0.2153 | Yes |
| 32 | Smurf1 | 14151 | -0.165 | -0.2028 | Yes |
| 33 | Ski | 14200 | -0.167 | -0.1900 | Yes |
| 34 | Ifngr2 | 14296 | -0.171 | -0.1793 | Yes |
| 35 | Smurf2 | 14357 | -0.175 | -0.1665 | Yes |
| 36 | Smad1 | 14697 | -0.189 | -0.1669 | Yes |
| 37 | Arid4b | 15020 | -0.205 | -0.1648 | Yes |
| 38 | Rab31 | 15255 | -0.217 | -0.1572 | Yes |
| 39 | Pmepa1 | 15319 | -0.220 | -0.1403 | Yes |
| 40 | Bmp2 | 15845 | -0.247 | -0.1450 | Yes |
| 41 | Apc | 15983 | -0.256 | -0.1287 | Yes |
| 42 | Junb | 16128 | -0.266 | -0.1119 | Yes |
| 43 | Rhoa | 16450 | -0.286 | -0.1024 | Yes |
| 44 | Acvr1 | 16846 | -0.313 | -0.0944 | Yes |
| 45 | Smad7 | 16888 | -0.316 | -0.0677 | Yes |
| 46 | Fkbp1a | 17171 | -0.341 | -0.0512 | Yes |
| 47 | Smad6 | 18616 | -0.509 | -0.0797 | Yes |
| 48 | Skil | 18808 | -0.556 | -0.0388 | Yes |
| 49 | Tjp1 | 19153 | -0.708 | 0.0080 | Yes |
