| Dataset | MEP.MEP.mega_Pheno.cls #Group1_versus_Group2.MEP.mega_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | MEP.mega_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_MYC_TARGETS_V1 |
| Enrichment Score (ES) | -0.24239923 |
| Normalized Enrichment Score (NES) | -0.8882359 |
| Nominal p-value | 0.5958763 |
| FDR q-value | 0.9957502 |
| FWER p-Value | 0.991 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Acp1 | 558 | 0.552 | -0.0095 | No |
| 2 | Mrps18b | 671 | 0.524 | 0.0033 | No |
| 3 | Cdc45 | 1821 | 0.367 | -0.0437 | No |
| 4 | Mcm7 | 1839 | 0.365 | -0.0316 | No |
| 5 | Cdk2 | 2354 | 0.322 | -0.0470 | No |
| 6 | Tfdp1 | 2466 | 0.312 | -0.0417 | No |
| 7 | Srsf2 | 2743 | 0.295 | -0.0456 | No |
| 8 | Mcm4 | 2749 | 0.294 | -0.0353 | No |
| 9 | Rfc4 | 2904 | 0.284 | -0.0333 | No |
| 10 | Ywhaq | 2962 | 0.280 | -0.0263 | No |
| 11 | Hnrnpc | 3238 | 0.263 | -0.0312 | No |
| 12 | Nolc1 | 3664 | 0.237 | -0.0450 | No |
| 13 | Ldha | 3786 | 0.231 | -0.0431 | No |
| 14 | Hnrnpd | 3822 | 0.229 | -0.0368 | No |
| 15 | Pwp1 | 3952 | 0.223 | -0.0356 | No |
| 16 | Eif4e | 4206 | 0.208 | -0.0414 | No |
| 17 | Psmd1 | 4306 | 0.204 | -0.0393 | No |
| 18 | Gm9531 | 4395 | 0.199 | -0.0368 | No |
| 19 | Pold2 | 4469 | 0.196 | -0.0336 | No |
| 20 | Mcm5 | 4622 | 0.189 | -0.0349 | No |
| 21 | Usp1 | 4926 | 0.174 | -0.0445 | No |
| 22 | Nme1 | 5009 | 0.170 | -0.0427 | No |
| 23 | Rrm1 | 5099 | 0.166 | -0.0415 | No |
| 24 | Sf3b3 | 5239 | 0.159 | -0.0431 | No |
| 25 | Cnbp | 5255 | 0.158 | -0.0382 | No |
| 26 | Nop56 | 5474 | 0.149 | -0.0443 | No |
| 27 | Exosc7 | 5813 | 0.135 | -0.0571 | No |
| 28 | Ifrd1 | 6014 | 0.127 | -0.0631 | No |
| 29 | Cul1 | 6098 | 0.124 | -0.0630 | No |
| 30 | Trim28 | 6143 | 0.122 | -0.0610 | No |
| 31 | Eif3d | 6144 | 0.122 | -0.0566 | No |
| 32 | Mcm2 | 6162 | 0.121 | -0.0532 | No |
| 33 | Dhx15 | 6288 | 0.117 | -0.0556 | No |
| 34 | Kpnb1 | 6298 | 0.117 | -0.0519 | No |
| 35 | Mcm6 | 6307 | 0.117 | -0.0481 | No |
| 36 | Ddx18 | 6337 | 0.115 | -0.0455 | No |
| 37 | Pgk1 | 6351 | 0.114 | -0.0421 | No |
| 38 | Xpo1 | 6482 | 0.110 | -0.0450 | No |
| 39 | Psma2 | 6597 | 0.105 | -0.0472 | No |
| 40 | Pabpc1 | 6632 | 0.104 | -0.0453 | No |
| 41 | Eif2s2 | 6767 | 0.098 | -0.0488 | No |
| 42 | Prpf31 | 6884 | 0.094 | -0.0515 | No |
| 43 | Prdx3 | 6948 | 0.092 | -0.0516 | No |
| 44 | Snrpd3 | 7024 | 0.089 | -0.0523 | No |
| 45 | Slc25a3 | 7085 | 0.087 | -0.0524 | No |
| 46 | Syncrip | 7175 | 0.083 | -0.0540 | No |
| 47 | Srm | 7206 | 0.082 | -0.0527 | No |
| 48 | Tardbp | 7238 | 0.081 | -0.0514 | No |
| 49 | Ndufab1 | 7317 | 0.078 | -0.0527 | No |
| 50 | Cox5a | 7382 | 0.075 | -0.0534 | No |
| 51 | Hnrnpa3 | 7493 | 0.072 | -0.0566 | No |
| 52 | Canx | 7624 | 0.068 | -0.0610 | No |
| 53 | Glo1 | 7717 | 0.064 | -0.0635 | No |
| 54 | Lsm2 | 7760 | 0.063 | -0.0635 | No |
| 55 | Ranbp1 | 7901 | 0.057 | -0.0687 | No |
| 56 | Tra2b | 7920 | 0.057 | -0.0676 | No |
| 57 | Hdac2 | 8043 | 0.052 | -0.0722 | No |
| 58 | Cct3 | 8061 | 0.052 | -0.0712 | No |
| 59 | Gspt1 | 8068 | 0.052 | -0.0697 | No |
| 60 | Prdx4 | 8116 | 0.050 | -0.0704 | No |
| 61 | Cbx3 | 8187 | 0.047 | -0.0723 | No |
| 62 | Ptges3-ps | 8285 | 0.044 | -0.0758 | No |
| 63 | Dek | 8347 | 0.043 | -0.0775 | No |
| 64 | Rrp9 | 8372 | 0.042 | -0.0773 | No |
| 65 | Rad23b | 8397 | 0.041 | -0.0770 | No |
| 66 | Dut | 8533 | 0.037 | -0.0828 | No |
| 67 | Hnrnpr | 8602 | 0.035 | -0.0851 | No |
| 68 | Xpot | 8638 | 0.034 | -0.0857 | No |
| 69 | Snrpb2 | 8721 | 0.031 | -0.0889 | No |
| 70 | Hnrnpa2b1 | 8763 | 0.029 | -0.0900 | No |
| 71 | Ncbp1 | 8811 | 0.027 | -0.0915 | No |
| 72 | Psmd7 | 8877 | 0.025 | -0.0940 | No |
| 73 | Tufm | 9155 | 0.016 | -0.1079 | No |
| 74 | Rsl1d1 | 9170 | 0.015 | -0.1081 | No |
| 75 | Ube2e1 | 9260 | 0.012 | -0.1124 | No |
| 76 | Rps2 | 9342 | 0.009 | -0.1163 | No |
| 77 | Fbl | 9432 | 0.006 | -0.1207 | No |
| 78 | Hnrnpa1 | 9455 | 0.006 | -0.1216 | No |
| 79 | Snrpa | 9528 | 0.003 | -0.1253 | No |
| 80 | Cct5 | 9540 | 0.003 | -0.1258 | No |
| 81 | Pabpc4 | 9567 | 0.002 | -0.1270 | No |
| 82 | Snrpd2 | 9613 | 0.001 | -0.1294 | No |
| 83 | Xrcc6 | 9671 | -0.000 | -0.1323 | No |
| 84 | Gnl3 | 9856 | -0.006 | -0.1417 | No |
| 85 | Nap1l1 | 9859 | -0.007 | -0.1416 | No |
| 86 | Psmd3 | 9899 | -0.008 | -0.1434 | No |
| 87 | Fam120a | 9913 | -0.009 | -0.1437 | No |
| 88 | Ddx21 | 10184 | -0.018 | -0.1572 | No |
| 89 | Cad | 10254 | -0.021 | -0.1601 | No |
| 90 | Srpk1 | 10335 | -0.023 | -0.1634 | No |
| 91 | Stard7 | 10443 | -0.027 | -0.1681 | No |
| 92 | Ppm1g | 10544 | -0.030 | -0.1722 | No |
| 93 | Orc2 | 10549 | -0.030 | -0.1714 | No |
| 94 | Sf3a1 | 10579 | -0.031 | -0.1718 | No |
| 95 | Hsp90ab1 | 10580 | -0.031 | -0.1707 | No |
| 96 | Smarcc1 | 10702 | -0.035 | -0.1758 | No |
| 97 | Clns1a | 10740 | -0.036 | -0.1764 | No |
| 98 | Snrpd1 | 10812 | -0.039 | -0.1787 | No |
| 99 | Cstf2 | 10879 | -0.041 | -0.1807 | No |
| 100 | Psma7 | 10890 | -0.041 | -0.1798 | No |
| 101 | Psma1 | 10913 | -0.042 | -0.1794 | No |
| 102 | Eif4g2 | 10963 | -0.043 | -0.1804 | No |
| 103 | Vdac3 | 11082 | -0.048 | -0.1849 | No |
| 104 | Hdgf | 11137 | -0.050 | -0.1860 | No |
| 105 | Nhp2 | 11253 | -0.054 | -0.1900 | No |
| 106 | Prps2 | 11327 | -0.056 | -0.1919 | No |
| 107 | Psma4 | 11342 | -0.057 | -0.1906 | No |
| 108 | Hnrnpu | 11526 | -0.064 | -0.1979 | No |
| 109 | Apex1 | 11536 | -0.064 | -0.1960 | No |
| 110 | Serbp1 | 11586 | -0.066 | -0.1962 | No |
| 111 | Erh | 11647 | -0.068 | -0.1969 | No |
| 112 | Rpl22 | 11737 | -0.071 | -0.1991 | No |
| 113 | Rack1 | 11808 | -0.073 | -0.2001 | No |
| 114 | Cdk4 | 12280 | -0.091 | -0.2215 | No |
| 115 | G3bp1 | 12340 | -0.094 | -0.2212 | No |
| 116 | Eif2s1 | 12383 | -0.095 | -0.2201 | No |
| 117 | Abce1 | 12539 | -0.102 | -0.2245 | No |
| 118 | Uba2 | 12649 | -0.106 | -0.2264 | No |
| 119 | Psmc6 | 12784 | -0.111 | -0.2295 | No |
| 120 | Cct2 | 12991 | -0.119 | -0.2360 | No |
| 121 | Rplp0 | 13077 | -0.121 | -0.2362 | No |
| 122 | Tyms | 13197 | -0.125 | -0.2379 | Yes |
| 123 | Odc1 | 13216 | -0.126 | -0.2344 | Yes |
| 124 | Ruvbl2 | 13234 | -0.127 | -0.2307 | Yes |
| 125 | Phb2 | 13242 | -0.127 | -0.2266 | Yes |
| 126 | Snrpa1 | 13259 | -0.127 | -0.2229 | Yes |
| 127 | Etf1 | 13261 | -0.127 | -0.2184 | Yes |
| 128 | Cct7 | 13289 | -0.129 | -0.2152 | Yes |
| 129 | Vdac1 | 13371 | -0.132 | -0.2147 | Yes |
| 130 | Cyc1 | 13507 | -0.137 | -0.2169 | Yes |
| 131 | Ap3s1 | 13548 | -0.139 | -0.2140 | Yes |
| 132 | Psmd8 | 13603 | -0.141 | -0.2118 | Yes |
| 133 | Eif3j1 | 13684 | -0.144 | -0.2109 | Yes |
| 134 | Pcna | 13687 | -0.144 | -0.2058 | Yes |
| 135 | Eef1b2 | 13693 | -0.145 | -0.2009 | Yes |
| 136 | Rpl14 | 13707 | -0.145 | -0.1964 | Yes |
| 137 | Ppia | 13863 | -0.153 | -0.1991 | Yes |
| 138 | Eif3b | 14009 | -0.160 | -0.2009 | Yes |
| 139 | Cct4 | 14019 | -0.160 | -0.1957 | Yes |
| 140 | Tomm70a | 14140 | -0.164 | -0.1961 | Yes |
| 141 | Ssb | 14169 | -0.166 | -0.1917 | Yes |
| 142 | Hspd1 | 14177 | -0.166 | -0.1861 | Yes |
| 143 | Psmd14 | 14270 | -0.170 | -0.1849 | Yes |
| 144 | Rps6 | 14307 | -0.172 | -0.1806 | Yes |
| 145 | Srsf3 | 14431 | -0.177 | -0.1807 | Yes |
| 146 | Srsf7 | 14537 | -0.183 | -0.1797 | Yes |
| 147 | Eif4a1 | 14545 | -0.183 | -0.1735 | Yes |
| 148 | Npm1 | 14593 | -0.184 | -0.1694 | Yes |
| 149 | Pa2g4 | 14731 | -0.191 | -0.1698 | Yes |
| 150 | Vbp1 | 14747 | -0.191 | -0.1637 | Yes |
| 151 | Ncbp2 | 14753 | -0.191 | -0.1572 | Yes |
| 152 | Eif4h | 14777 | -0.192 | -0.1515 | Yes |
| 153 | Txnl4a | 14939 | -0.201 | -0.1528 | Yes |
| 154 | Tcp1 | 15043 | -0.206 | -0.1508 | Yes |
| 155 | Mrpl23 | 15207 | -0.215 | -0.1517 | Yes |
| 156 | Mad2l1 | 15229 | -0.215 | -0.1451 | Yes |
| 157 | Impdh2 | 15251 | -0.216 | -0.1385 | Yes |
| 158 | H2az1 | 15327 | -0.221 | -0.1345 | Yes |
| 159 | Cops5 | 15461 | -0.228 | -0.1334 | Yes |
| 160 | Ilf2 | 15608 | -0.235 | -0.1326 | Yes |
| 161 | Rpl6 | 15619 | -0.236 | -0.1247 | Yes |
| 162 | Ywhae | 15622 | -0.236 | -0.1164 | Yes |
| 163 | Ssbp1 | 15734 | -0.242 | -0.1135 | Yes |
| 164 | Rps10 | 15806 | -0.245 | -0.1085 | Yes |
| 165 | Hspe1 | 15889 | -0.250 | -0.1039 | Yes |
| 166 | Myc | 15993 | -0.257 | -0.1001 | Yes |
| 167 | Mrpl9 | 16022 | -0.259 | -0.0923 | Yes |
| 168 | Snrpg | 16287 | -0.276 | -0.0963 | Yes |
| 169 | C1qbp | 16353 | -0.280 | -0.0897 | Yes |
| 170 | Psma6 | 16382 | -0.282 | -0.0811 | Yes |
| 171 | Pole3 | 16398 | -0.283 | -0.0718 | Yes |
| 172 | Pcbp1 | 16517 | -0.290 | -0.0676 | Yes |
| 173 | Got2 | 16559 | -0.294 | -0.0593 | Yes |
| 174 | Bub3 | 16601 | -0.297 | -0.0509 | Yes |
| 175 | Nop16 | 16770 | -0.307 | -0.0487 | Yes |
| 176 | Psmb2 | 16929 | -0.320 | -0.0455 | Yes |
| 177 | Rps3 | 16998 | -0.325 | -0.0375 | Yes |
| 178 | Srsf1 | 17008 | -0.326 | -0.0263 | Yes |
| 179 | Psmc4 | 17015 | -0.327 | -0.0150 | Yes |
| 180 | Rnps1 | 17128 | -0.337 | -0.0088 | Yes |
| 181 | Psmb3 | 17422 | -0.361 | -0.0113 | Yes |
| 182 | Rpl18 | 17430 | -0.362 | 0.0013 | Yes |
| 183 | Hddc2 | 17581 | -0.373 | 0.0067 | Yes |
| 184 | Cdc20 | 17959 | -0.412 | 0.0017 | Yes |
| 185 | Ccna2 | 18113 | -0.429 | 0.0090 | Yes |
| 186 | Rps5 | 18180 | -0.436 | 0.0211 | Yes |
| 187 | Ran | 18699 | -0.529 | 0.0129 | Yes |
| 188 | Aimp2 | 18700 | -0.530 | 0.0317 | Yes |

