Details for gene set HALLMARK_IL6_JAK_STAT3

Table: GSEA Results Summary

Dataset	MEP.MEP.mega_Pheno.cls #Group1_versus_Group2.MEP.mega_Pheno.cls #Group1_versus_Group2_repos
Phenotype	MEP.mega_Pheno.cls#Group1_versus_Group2_repos
Upregulated in class	1
GeneSet	HALLMARK_IL6_JAK_STAT3_SIGNALING
Enrichment Score (ES)	-0.30615208
Normalized Enrichment Score (NES)	-1.1654323
Nominal p-value	0.22075471
FDR q-value	1.0
FWER p-Value	0.928

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Il3ra	330	0.624	0.0208	No
2	Il10rb	488	0.569	0.0473	No
3	Tnf	533	0.557	0.0789	No
4	Cd36	1017	0.460	0.0818	No
5	Ccr1	1436	0.404	0.0846	No
6	Hmox1	1498	0.398	0.1057	No
7	Csf2ra	1737	0.375	0.1161	No
8	Il17rb	2010	0.349	0.1232	No
9	Cd38	2104	0.340	0.1391	No
10	Tnfrsf21	2137	0.338	0.1580	No
11	Ltbr	2914	0.283	0.1349	No
12	Cxcl10	3511	0.246	0.1189	No
13	Dntt	4196	0.209	0.0960	No
14	Pf4	4483	0.195	0.0930	No
15	Bak1	5382	0.153	0.0556	No
16	Grb2	5413	0.151	0.0633	No
17	Crlf2	5592	0.144	0.0628	No
18	Tyk2	5657	0.142	0.0681	No
19	Cd9	6093	0.124	0.0530	No
20	Tnfrsf1a	6125	0.122	0.0589	No
21	Il13ra1	6187	0.120	0.0630	No
22	Stam2	6236	0.119	0.0678	No
23	Il7	6636	0.103	0.0533	No
24	Ptpn11	6754	0.099	0.0533	No
25	Jun	7239	0.081	0.0330	No
26	Fas	7275	0.079	0.0360	No
27	Socs1	8426	0.040	-0.0213	No
28	Csf3r	8783	0.028	-0.0380	No
29	Ptpn2	8994	0.021	-0.0477	No
30	Il12rb1	9683	-0.001	-0.0834	No
31	Tgfb1	9845	-0.006	-0.0914	No
32	Il17ra	10011	-0.012	-0.0992	No
33	Stat1	10203	-0.019	-0.1080	No
34	Itga4	10450	-0.027	-0.1192	No
35	Map3k8	10577	-0.031	-0.1238	No
36	Ptpn1	10951	-0.043	-0.1406	No
37	Pdgfc	11085	-0.048	-0.1446	No
38	Ltb	11248	-0.054	-0.1498	No
39	Socs3	11463	-0.062	-0.1571	No
40	Ifnar1	11553	-0.065	-0.1578	No
41	Cbl	12091	-0.085	-0.1805	No
42	Csf1	12129	-0.087	-0.1772	No
43	Itgb3	12496	-0.099	-0.1901	No
44	Il15ra	12622	-0.105	-0.1902	No
45	Cd44	12726	-0.109	-0.1889	No
46	Pik3r5	12738	-0.110	-0.1828	No
47	Il1r1	12884	-0.114	-0.1834	No
48	Hax1	12979	-0.118	-0.1811	No
49	Lepr	13018	-0.119	-0.1758	No
50	Il18r1	13248	-0.127	-0.1800	No
51	Ifngr2	14296	-0.171	-0.2240	No
52	Tnfrsf1b	14900	-0.199	-0.2432	No
53	Stat2	16112	-0.265	-0.2900	Yes
54	Il2rg	16122	-0.266	-0.2743	Yes
55	Ebi3	16216	-0.272	-0.2626	Yes
56	Ifngr1	16931	-0.321	-0.2802	Yes
57	Il6st	17027	-0.328	-0.2652	Yes
58	Tlr2	17030	-0.328	-0.2453	Yes
59	Stat3	17440	-0.363	-0.2445	Yes
60	Pim1	17541	-0.370	-0.2271	Yes
61	Il4ra	17887	-0.404	-0.2204	Yes
62	Il1r2	17968	-0.412	-0.1995	Yes
63	Irf1	18157	-0.434	-0.1829	Yes
64	Acvr1b	18351	-0.461	-0.1649	Yes
65	Myd88	18515	-0.490	-0.1435	Yes
66	Irf9	19108	-0.673	-0.1333	Yes
67	Il1b	19189	-0.746	-0.0921	Yes
68	Il6	19208	-0.767	-0.0463	Yes
69	Tnfrsf12a	19255	-0.844	0.0027	Yes