| Dataset | MEP.MEP.mega_Pheno.cls #Group1_versus_Group2.MEP.mega_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | MEP.mega_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_COMPLEMENT |
| Enrichment Score (ES) | -0.23627993 |
| Normalized Enrichment Score (NES) | -1.0195332 |
| Nominal p-value | 0.4186508 |
| FDR q-value | 0.98695457 |
| FWER p-Value | 0.983 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Me1 | 187 | 0.698 | 0.0101 | No |
| 2 | Timp2 | 249 | 0.662 | 0.0257 | No |
| 3 | Pdgfb | 296 | 0.640 | 0.0415 | No |
| 4 | F7 | 376 | 0.606 | 0.0546 | No |
| 5 | Phex | 602 | 0.536 | 0.0581 | No |
| 6 | Gzmk | 682 | 0.521 | 0.0688 | No |
| 7 | Cebpb | 973 | 0.467 | 0.0669 | No |
| 8 | Cd36 | 1017 | 0.460 | 0.0778 | No |
| 9 | Ppp2cb | 1042 | 0.456 | 0.0895 | No |
| 10 | C3 | 1223 | 0.429 | 0.0923 | No |
| 11 | Prdm4 | 1282 | 0.422 | 0.1012 | No |
| 12 | C2 | 1458 | 0.402 | 0.1035 | No |
| 13 | Brpf3 | 1462 | 0.401 | 0.1147 | No |
| 14 | F8 | 1476 | 0.400 | 0.1254 | No |
| 15 | Hnf4a | 1651 | 0.382 | 0.1272 | No |
| 16 | Kcnip3 | 1697 | 0.378 | 0.1356 | No |
| 17 | Gca | 2068 | 0.343 | 0.1260 | No |
| 18 | Pik3cg | 2105 | 0.340 | 0.1338 | No |
| 19 | Lrp1 | 2493 | 0.310 | 0.1224 | No |
| 20 | Tfpi2 | 2534 | 0.307 | 0.1290 | No |
| 21 | L3mbtl4 | 2563 | 0.307 | 0.1363 | No |
| 22 | Cdh13 | 2789 | 0.292 | 0.1328 | No |
| 23 | Dgkg | 2815 | 0.291 | 0.1398 | No |
| 24 | Gngt2 | 3215 | 0.265 | 0.1265 | No |
| 25 | Dpp4 | 3445 | 0.251 | 0.1216 | No |
| 26 | Casp7 | 3463 | 0.249 | 0.1278 | No |
| 27 | Plek | 3740 | 0.233 | 0.1200 | No |
| 28 | Xpnpep1 | 3845 | 0.227 | 0.1211 | No |
| 29 | Prss36 | 4024 | 0.219 | 0.1180 | No |
| 30 | Ctsl | 4349 | 0.202 | 0.1068 | No |
| 31 | Usp14 | 4381 | 0.200 | 0.1109 | No |
| 32 | Rasgrp1 | 4442 | 0.197 | 0.1133 | No |
| 33 | Fcer1g | 4472 | 0.196 | 0.1174 | No |
| 34 | Rabif | 4559 | 0.192 | 0.1183 | No |
| 35 | Plg | 4690 | 0.185 | 0.1168 | No |
| 36 | Pfn1 | 4801 | 0.179 | 0.1161 | No |
| 37 | Mmp15 | 5073 | 0.167 | 0.1067 | No |
| 38 | Olr1 | 5153 | 0.163 | 0.1072 | No |
| 39 | Actn2 | 5291 | 0.157 | 0.1045 | No |
| 40 | Src | 5367 | 0.153 | 0.1050 | No |
| 41 | Cfb | 5381 | 0.153 | 0.1086 | No |
| 42 | Hspa5 | 5397 | 0.152 | 0.1121 | No |
| 43 | Grb2 | 5413 | 0.151 | 0.1157 | No |
| 44 | Rce1 | 5467 | 0.149 | 0.1171 | No |
| 45 | Sirt6 | 5477 | 0.149 | 0.1209 | No |
| 46 | Cda | 5607 | 0.144 | 0.1182 | No |
| 47 | Gp1ba | 5756 | 0.138 | 0.1144 | No |
| 48 | Gzmb | 5815 | 0.135 | 0.1152 | No |
| 49 | Ccl5 | 5978 | 0.128 | 0.1104 | No |
| 50 | Lap3 | 6003 | 0.127 | 0.1128 | No |
| 51 | Gpd2 | 6292 | 0.117 | 0.1010 | No |
| 52 | Fdx1 | 6438 | 0.111 | 0.0966 | No |
| 53 | Pdp1 | 6478 | 0.110 | 0.0977 | No |
| 54 | Gata3 | 6489 | 0.109 | 0.1003 | No |
| 55 | Dyrk2 | 6496 | 0.109 | 0.1031 | No |
| 56 | Plscr1 | 6741 | 0.099 | 0.0932 | No |
| 57 | Irf7 | 6743 | 0.099 | 0.0959 | No |
| 58 | Casp9 | 6878 | 0.094 | 0.0916 | No |
| 59 | Rnf4 | 6912 | 0.093 | 0.0926 | No |
| 60 | Calm1 | 7055 | 0.088 | 0.0876 | No |
| 61 | Irf2 | 7230 | 0.081 | 0.0809 | No |
| 62 | Usp8 | 7333 | 0.077 | 0.0777 | No |
| 63 | Lcp2 | 7353 | 0.076 | 0.0789 | No |
| 64 | Dgkh | 7502 | 0.071 | 0.0732 | No |
| 65 | Gmfb | 7541 | 0.070 | 0.0732 | No |
| 66 | F10 | 7564 | 0.070 | 0.0740 | No |
| 67 | Rbsn | 7599 | 0.068 | 0.0742 | No |
| 68 | Usp16 | 7615 | 0.068 | 0.0754 | No |
| 69 | Pla2g4a | 7749 | 0.063 | 0.0702 | No |
| 70 | Cp | 8106 | 0.050 | 0.0530 | No |
| 71 | Gnai3 | 8337 | 0.043 | 0.0422 | No |
| 72 | Ctsd | 8339 | 0.043 | 0.0434 | No |
| 73 | Gng2 | 8447 | 0.040 | 0.0389 | No |
| 74 | Fcnb | 8527 | 0.037 | 0.0359 | No |
| 75 | Raf1 | 8537 | 0.037 | 0.0364 | No |
| 76 | Jak2 | 8547 | 0.037 | 0.0370 | No |
| 77 | Serpinb2 | 8609 | 0.035 | 0.0348 | No |
| 78 | Kcnip2 | 8665 | 0.033 | 0.0329 | No |
| 79 | Ctss | 8819 | 0.027 | 0.0256 | No |
| 80 | Lck | 8864 | 0.025 | 0.0241 | No |
| 81 | F5 | 8875 | 0.025 | 0.0242 | No |
| 82 | Was | 8897 | 0.024 | 0.0238 | No |
| 83 | Prep | 9015 | 0.020 | 0.0183 | No |
| 84 | Dock4 | 9020 | 0.020 | 0.0186 | No |
| 85 | Sh2b3 | 9084 | 0.018 | 0.0159 | No |
| 86 | Ctso | 9097 | 0.018 | 0.0158 | No |
| 87 | Atox1 | 9162 | 0.015 | 0.0128 | No |
| 88 | Dusp5 | 9289 | 0.011 | 0.0066 | No |
| 89 | Gp9 | 9447 | 0.006 | -0.0015 | No |
| 90 | Cpq | 9558 | 0.002 | -0.0071 | No |
| 91 | Ltf | 9625 | 0.000 | -0.0106 | No |
| 92 | Dock9 | 9705 | -0.002 | -0.0147 | No |
| 93 | F2 | 9906 | -0.008 | -0.0249 | No |
| 94 | Pik3ca | 9986 | -0.011 | -0.0287 | No |
| 95 | Vcpip1 | 10091 | -0.014 | -0.0337 | No |
| 96 | Kif2a | 10121 | -0.016 | -0.0348 | No |
| 97 | Lta4h | 10340 | -0.023 | -0.0455 | No |
| 98 | Msrb1 | 10363 | -0.024 | -0.0459 | No |
| 99 | Csrp1 | 10567 | -0.031 | -0.0557 | No |
| 100 | Akap10 | 10641 | -0.033 | -0.0585 | No |
| 101 | Ehd1 | 10770 | -0.037 | -0.0642 | No |
| 102 | Cblb | 11003 | -0.045 | -0.0750 | No |
| 103 | Casp3 | 11057 | -0.047 | -0.0765 | No |
| 104 | Itgam | 11154 | -0.050 | -0.0800 | No |
| 105 | Gnai2 | 11421 | -0.060 | -0.0922 | No |
| 106 | Usp15 | 11540 | -0.064 | -0.0966 | No |
| 107 | Fyn | 11700 | -0.070 | -0.1029 | No |
| 108 | Dock10 | 12027 | -0.083 | -0.1176 | No |
| 109 | Prcp | 12146 | -0.088 | -0.1212 | No |
| 110 | Clu | 12148 | -0.088 | -0.1188 | No |
| 111 | Tmprss6 | 12231 | -0.090 | -0.1205 | No |
| 112 | Zeb1 | 12479 | -0.099 | -0.1306 | No |
| 113 | Car2 | 12485 | -0.099 | -0.1280 | No |
| 114 | Ctsb | 12512 | -0.100 | -0.1266 | No |
| 115 | Fn1 | 12697 | -0.108 | -0.1331 | No |
| 116 | Pik3r5 | 12738 | -0.110 | -0.1321 | No |
| 117 | Psen1 | 12753 | -0.110 | -0.1297 | No |
| 118 | Stx4a | 12826 | -0.112 | -0.1302 | No |
| 119 | Calm3 | 12947 | -0.117 | -0.1332 | No |
| 120 | Dusp6 | 13050 | -0.120 | -0.1351 | No |
| 121 | Mmp14 | 13144 | -0.123 | -0.1365 | No |
| 122 | Gnb4 | 13179 | -0.125 | -0.1347 | No |
| 123 | Gnb2 | 13333 | -0.131 | -0.1390 | No |
| 124 | Lyn | 14419 | -0.177 | -0.1906 | No |
| 125 | Hspa1a | 14474 | -0.179 | -0.1883 | No |
| 126 | Prkcd | 14606 | -0.185 | -0.1899 | No |
| 127 | Anxa5 | 14724 | -0.190 | -0.1906 | No |
| 128 | Lgals3 | 15028 | -0.206 | -0.2006 | No |
| 129 | Cr2 | 15649 | -0.239 | -0.2262 | No |
| 130 | S100a9 | 15821 | -0.246 | -0.2282 | No |
| 131 | Maff | 15859 | -0.248 | -0.2230 | No |
| 132 | Ppp4c | 15893 | -0.251 | -0.2176 | No |
| 133 | Lgmn | 16251 | -0.273 | -0.2285 | Yes |
| 134 | Klkb1 | 16323 | -0.278 | -0.2243 | Yes |
| 135 | Lamp2 | 16408 | -0.284 | -0.2206 | Yes |
| 136 | Cpm | 16508 | -0.289 | -0.2176 | Yes |
| 137 | Lipa | 16727 | -0.305 | -0.2203 | Yes |
| 138 | Pclo | 16763 | -0.307 | -0.2134 | Yes |
| 139 | C1qc | 16976 | -0.323 | -0.2153 | Yes |
| 140 | Kynu | 17150 | -0.338 | -0.2147 | Yes |
| 141 | Casp1 | 17234 | -0.346 | -0.2092 | Yes |
| 142 | Pla2g7 | 17416 | -0.361 | -0.2084 | Yes |
| 143 | Adam9 | 17515 | -0.368 | -0.2031 | Yes |
| 144 | Pim1 | 17541 | -0.370 | -0.1939 | Yes |
| 145 | Cd46 | 17562 | -0.372 | -0.1843 | Yes |
| 146 | Spock2 | 17647 | -0.381 | -0.1779 | Yes |
| 147 | Rhog | 18038 | -0.420 | -0.1863 | Yes |
| 148 | S100a13 | 18055 | -0.422 | -0.1752 | Yes |
| 149 | Irf1 | 18157 | -0.434 | -0.1681 | Yes |
| 150 | Notch4 | 18223 | -0.443 | -0.1589 | Yes |
| 151 | Col4a2 | 18256 | -0.447 | -0.1479 | Yes |
| 152 | Tnfaip3 | 18481 | -0.480 | -0.1460 | Yes |
| 153 | Psmb9 | 18521 | -0.492 | -0.1340 | Yes |
| 154 | Zfpm2 | 18632 | -0.512 | -0.1252 | Yes |
| 155 | Ctsc | 18752 | -0.539 | -0.1161 | Yes |
| 156 | Pcsk9 | 18832 | -0.564 | -0.1042 | Yes |
| 157 | Casp4 | 18909 | -0.583 | -0.0916 | Yes |
| 158 | Ctsh | 18939 | -0.594 | -0.0762 | Yes |
| 159 | Serpinc1 | 19097 | -0.667 | -0.0654 | Yes |
| 160 | Cdk5r1 | 19124 | -0.687 | -0.0473 | Yes |
| 161 | Il6 | 19208 | -0.767 | -0.0298 | Yes |
| 162 | Plaur | 19303 | -1.228 | 0.0002 | Yes |

