| Dataset | MEP.MEP.ery_Pheno.cls #Group6_versus_Group8.MEP.ery_Pheno.cls #Group6_versus_Group8_repos |
| Phenotype | MEP.ery_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | -0.21569432 |
| Normalized Enrichment Score (NES) | -1.0694921 |
| Nominal p-value | 0.3902439 |
| FDR q-value | 0.64277756 |
| FWER p-Value | 0.928 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Shmt1 | 3351 | 0.318 | -0.1052 | No |
| 2 | Ccp110 | 4611 | 0.248 | -0.1378 | No |
| 3 | Pole | 4734 | 0.242 | -0.1292 | No |
| 4 | Ube2s | 4935 | 0.233 | -0.1239 | No |
| 5 | Mki67 | 5137 | 0.225 | -0.1191 | No |
| 6 | Tbrg4 | 5287 | 0.217 | -0.1128 | No |
| 7 | Slbp | 5810 | 0.198 | -0.1213 | No |
| 8 | Aurka | 6423 | 0.175 | -0.1341 | No |
| 9 | Lbr | 6727 | 0.165 | -0.1363 | No |
| 10 | Ube2t | 6914 | 0.159 | -0.1345 | No |
| 11 | Dnmt1 | 6995 | 0.157 | -0.1289 | No |
| 12 | Pola2 | 7088 | 0.154 | -0.1240 | No |
| 13 | Anp32e | 7252 | 0.148 | -0.1219 | No |
| 14 | Ilf3 | 7572 | 0.138 | -0.1261 | No |
| 15 | Mcm5 | 7607 | 0.137 | -0.1200 | No |
| 16 | Nup153 | 7665 | 0.136 | -0.1147 | No |
| 17 | Pan2 | 7873 | 0.130 | -0.1153 | No |
| 18 | Pnn | 8190 | 0.122 | -0.1202 | No |
| 19 | Ipo7 | 8577 | 0.112 | -0.1283 | No |
| 20 | Tra2b | 8715 | 0.108 | -0.1274 | No |
| 21 | Mybl2 | 9078 | 0.099 | -0.1353 | No |
| 22 | Cit | 9095 | 0.099 | -0.1305 | No |
| 23 | Dclre1b | 9111 | 0.099 | -0.1258 | No |
| 24 | Pttg1 | 9284 | 0.095 | -0.1269 | No |
| 25 | Dctpp1 | 9292 | 0.094 | -0.1221 | No |
| 26 | Rad21 | 9313 | 0.094 | -0.1178 | No |
| 27 | Tfrc | 9473 | 0.091 | -0.1187 | No |
| 28 | Gins1 | 9504 | 0.090 | -0.1150 | No |
| 29 | Ppm1d | 9538 | 0.089 | -0.1114 | No |
| 30 | Cse1l | 9569 | 0.089 | -0.1077 | No |
| 31 | Stag1 | 9579 | 0.089 | -0.1032 | No |
| 32 | Atad2 | 9673 | 0.086 | -0.1020 | No |
| 33 | Pcna | 9701 | 0.085 | -0.0984 | No |
| 34 | Prim2 | 9721 | 0.085 | -0.0945 | No |
| 35 | Mcm6 | 9856 | 0.082 | -0.0949 | No |
| 36 | Espl1 | 9923 | 0.081 | -0.0930 | No |
| 37 | Diaph3 | 10195 | 0.075 | -0.0988 | No |
| 38 | Tacc3 | 10301 | 0.073 | -0.0988 | No |
| 39 | Nup107 | 10354 | 0.072 | -0.0968 | No |
| 40 | Pms2 | 10366 | 0.071 | -0.0934 | No |
| 41 | Xpo1 | 10466 | 0.069 | -0.0932 | No |
| 42 | Dlgap5 | 10567 | 0.067 | -0.0933 | No |
| 43 | Bub1b | 10633 | 0.066 | -0.0921 | No |
| 44 | Mre11a | 10800 | 0.063 | -0.0948 | No |
| 45 | Tk1 | 10999 | 0.059 | -0.0988 | No |
| 46 | Cdkn2c | 11008 | 0.059 | -0.0959 | No |
| 47 | Eed | 11075 | 0.058 | -0.0952 | No |
| 48 | Hells | 11133 | 0.057 | -0.0942 | No |
| 49 | Nasp | 11142 | 0.056 | -0.0915 | No |
| 50 | Psmc3ip | 11367 | 0.052 | -0.0969 | No |
| 51 | Wee1 | 11410 | 0.051 | -0.0957 | No |
| 52 | Bard1 | 11604 | 0.047 | -0.1002 | No |
| 53 | Cbx5 | 11689 | 0.046 | -0.1008 | No |
| 54 | Ccne1 | 11773 | 0.044 | -0.1014 | No |
| 55 | Eif2s1 | 11795 | 0.044 | -0.0998 | No |
| 56 | Gins4 | 11797 | 0.044 | -0.0975 | No |
| 57 | Birc5 | 11873 | 0.042 | -0.0980 | No |
| 58 | Nup205 | 12082 | 0.038 | -0.1035 | No |
| 59 | Pds5b | 12165 | 0.037 | -0.1045 | No |
| 60 | Nop56 | 12221 | 0.035 | -0.1046 | No |
| 61 | Xrcc6 | 12285 | 0.034 | -0.1051 | No |
| 62 | Mms22l | 12403 | 0.032 | -0.1077 | No |
| 63 | Trp53 | 12445 | 0.031 | -0.1075 | No |
| 64 | Dscc1 | 12462 | 0.031 | -0.1064 | No |
| 65 | Wdr90 | 12600 | 0.028 | -0.1099 | No |
| 66 | Hus1 | 12980 | 0.022 | -0.1226 | No |
| 67 | Tcf19 | 13028 | 0.021 | -0.1231 | No |
| 68 | Plk1 | 13038 | 0.021 | -0.1223 | No |
| 69 | Mcm4 | 13150 | 0.019 | -0.1254 | No |
| 70 | Pold1 | 13202 | 0.018 | -0.1263 | No |
| 71 | Prkdc | 13239 | 0.017 | -0.1267 | No |
| 72 | Brca2 | 13366 | 0.015 | -0.1305 | No |
| 73 | Stmn1 | 13453 | 0.013 | -0.1329 | No |
| 74 | Cdc25b | 13672 | 0.009 | -0.1404 | No |
| 75 | Tmpo | 13927 | 0.005 | -0.1494 | No |
| 76 | Lig1 | 14006 | 0.003 | -0.1521 | No |
| 77 | Orc2 | 14014 | 0.003 | -0.1522 | No |
| 78 | Srsf2 | 14454 | -0.003 | -0.1681 | No |
| 79 | Suv39h1 | 14521 | -0.004 | -0.1702 | No |
| 80 | Pa2g4 | 14583 | -0.005 | -0.1722 | No |
| 81 | Cks2 | 14659 | -0.006 | -0.1746 | No |
| 82 | Mcm3 | 14675 | -0.007 | -0.1748 | No |
| 83 | Smc1a | 14682 | -0.007 | -0.1746 | No |
| 84 | H2az1 | 14770 | -0.008 | -0.1773 | No |
| 85 | Kif4 | 14836 | -0.010 | -0.1792 | No |
| 86 | Rnaseh2a | 14963 | -0.012 | -0.1832 | No |
| 87 | Brca1 | 15012 | -0.013 | -0.1842 | No |
| 88 | Dck | 15071 | -0.014 | -0.1856 | No |
| 89 | Cdkn1a | 15145 | -0.015 | -0.1875 | No |
| 90 | Tipin | 15154 | -0.015 | -0.1869 | No |
| 91 | Gins3 | 15168 | -0.016 | -0.1865 | No |
| 92 | E2f8 | 15248 | -0.017 | -0.1885 | No |
| 93 | Ezh2 | 15318 | -0.018 | -0.1900 | No |
| 94 | Ctcf | 15326 | -0.019 | -0.1893 | No |
| 95 | Cdc25a | 15558 | -0.023 | -0.1965 | No |
| 96 | Kif18b | 15601 | -0.024 | -0.1968 | No |
| 97 | Prps1 | 15608 | -0.024 | -0.1957 | No |
| 98 | Mlh1 | 15652 | -0.025 | -0.1959 | No |
| 99 | Mthfd2 | 15730 | -0.026 | -0.1973 | No |
| 100 | Racgap1 | 15758 | -0.027 | -0.1969 | No |
| 101 | Lmnb1 | 15799 | -0.027 | -0.1969 | No |
| 102 | Spag5 | 15915 | -0.030 | -0.1995 | No |
| 103 | Cenpm | 15927 | -0.030 | -0.1983 | No |
| 104 | Mad2l1 | 15952 | -0.030 | -0.1975 | No |
| 105 | Cdkn1b | 16055 | -0.032 | -0.1995 | No |
| 106 | Msh2 | 16212 | -0.035 | -0.2033 | No |
| 107 | Rfc1 | 16233 | -0.035 | -0.2021 | No |
| 108 | Ing3 | 16366 | -0.038 | -0.2049 | No |
| 109 | Smc6 | 16506 | -0.041 | -0.2078 | No |
| 110 | Cnot9 | 16562 | -0.042 | -0.2075 | No |
| 111 | Smc3 | 16576 | -0.042 | -0.2057 | No |
| 112 | Rad50 | 16581 | -0.042 | -0.2036 | No |
| 113 | Ranbp1 | 16673 | -0.044 | -0.2045 | No |
| 114 | Brms1l | 16847 | -0.047 | -0.2083 | No |
| 115 | Hmmr | 16903 | -0.049 | -0.2076 | No |
| 116 | Mcm2 | 16961 | -0.050 | -0.2070 | No |
| 117 | Depdc1a | 17051 | -0.052 | -0.2075 | No |
| 118 | Syncrip | 17213 | -0.055 | -0.2104 | No |
| 119 | Nbn | 17248 | -0.056 | -0.2087 | No |
| 120 | Ddx39a | 17442 | -0.059 | -0.2125 | Yes |
| 121 | Phf5a | 17502 | -0.061 | -0.2114 | Yes |
| 122 | Cdca8 | 17530 | -0.061 | -0.2091 | Yes |
| 123 | Ssrp1 | 17539 | -0.062 | -0.2060 | Yes |
| 124 | Kif22 | 17657 | -0.064 | -0.2069 | Yes |
| 125 | Rad51c | 17705 | -0.065 | -0.2051 | Yes |
| 126 | Kif2c | 17711 | -0.065 | -0.2018 | Yes |
| 127 | Zw10 | 17770 | -0.066 | -0.2003 | Yes |
| 128 | Smc4 | 17771 | -0.066 | -0.1967 | Yes |
| 129 | Hmgb3 | 17800 | -0.067 | -0.1941 | Yes |
| 130 | Usp1 | 18021 | -0.072 | -0.1983 | Yes |
| 131 | Dek | 18169 | -0.075 | -0.1996 | Yes |
| 132 | Rfc2 | 18205 | -0.076 | -0.1968 | Yes |
| 133 | Lsm8 | 18318 | -0.078 | -0.1966 | Yes |
| 134 | Mxd3 | 18411 | -0.081 | -0.1956 | Yes |
| 135 | Cdkn3 | 18474 | -0.083 | -0.1934 | Yes |
| 136 | Spc25 | 18593 | -0.085 | -0.1931 | Yes |
| 137 | Orc6 | 18600 | -0.086 | -0.1887 | Yes |
| 138 | Chek2 | 18610 | -0.086 | -0.1844 | Yes |
| 139 | Gspt1 | 18638 | -0.086 | -0.1808 | Yes |
| 140 | Rpa1 | 18640 | -0.086 | -0.1762 | Yes |
| 141 | Pop7 | 18860 | -0.091 | -0.1793 | Yes |
| 142 | Psip1 | 18962 | -0.093 | -0.1779 | Yes |
| 143 | Plk4 | 19010 | -0.095 | -0.1745 | Yes |
| 144 | Pole4 | 19013 | -0.095 | -0.1695 | Yes |
| 145 | Rfc3 | 19123 | -0.098 | -0.1682 | Yes |
| 146 | Ncapd2 | 19134 | -0.098 | -0.1633 | Yes |
| 147 | Nap1l1 | 19220 | -0.100 | -0.1610 | Yes |
| 148 | Cenpe | 19241 | -0.100 | -0.1564 | Yes |
| 149 | Timeless | 19249 | -0.100 | -0.1512 | Yes |
| 150 | Aurkb | 19269 | -0.101 | -0.1465 | Yes |
| 151 | Cdk1 | 19270 | -0.101 | -0.1410 | Yes |
| 152 | Top2a | 19431 | -0.105 | -0.1412 | Yes |
| 153 | Hnrnpd | 19445 | -0.105 | -0.1360 | Yes |
| 154 | Lyar | 19504 | -0.107 | -0.1324 | Yes |
| 155 | Rad51ap1 | 19541 | -0.108 | -0.1279 | Yes |
| 156 | Luc7l3 | 19558 | -0.108 | -0.1226 | Yes |
| 157 | Rrm2 | 19583 | -0.109 | -0.1176 | Yes |
| 158 | Cdca3 | 19584 | -0.109 | -0.1118 | Yes |
| 159 | Paics | 19638 | -0.110 | -0.1078 | Yes |
| 160 | Donson | 19708 | -0.112 | -0.1043 | Yes |
| 161 | Pold2 | 19805 | -0.114 | -0.1016 | Yes |
| 162 | Asf1a | 19915 | -0.116 | -0.0993 | Yes |
| 163 | Nme1 | 20037 | -0.119 | -0.0973 | Yes |
| 164 | Pold3 | 20219 | -0.123 | -0.0973 | Yes |
| 165 | Nolc1 | 20236 | -0.123 | -0.0912 | Yes |
| 166 | Srsf1 | 20313 | -0.126 | -0.0873 | Yes |
| 167 | Rad1 | 20513 | -0.130 | -0.0875 | Yes |
| 168 | Melk | 20551 | -0.132 | -0.0817 | Yes |
| 169 | H2ax | 20598 | -0.133 | -0.0763 | Yes |
| 170 | Cdk4 | 20661 | -0.135 | -0.0712 | Yes |
| 171 | Nudt21 | 20773 | -0.138 | -0.0678 | Yes |
| 172 | Tubg1 | 20875 | -0.141 | -0.0639 | Yes |
| 173 | Mcm7 | 20885 | -0.141 | -0.0566 | Yes |
| 174 | Ppp1r8 | 21021 | -0.145 | -0.0538 | Yes |
| 175 | Ubr7 | 21312 | -0.154 | -0.0560 | Yes |
| 176 | Chek1 | 21338 | -0.155 | -0.0486 | Yes |
| 177 | Ung | 21470 | -0.159 | -0.0448 | Yes |
| 178 | Ak2 | 21479 | -0.159 | -0.0365 | Yes |
| 179 | Spc24 | 21557 | -0.162 | -0.0306 | Yes |
| 180 | Dut | 21579 | -0.162 | -0.0227 | Yes |
| 181 | Rbbp7 | 21676 | -0.165 | -0.0172 | Yes |
| 182 | Snrpb | 21818 | -0.171 | -0.0132 | Yes |
| 183 | Jpt1 | 22210 | -0.182 | -0.0177 | Yes |
| 184 | Trip13 | 22330 | -0.187 | -0.0119 | Yes |
| 185 | Hmgb2 | 22354 | -0.188 | -0.0026 | Yes |
| 186 | Asf1b | 22462 | -0.192 | 0.0038 | Yes |
| 187 | Ran | 22540 | -0.195 | 0.0115 | Yes |
| 188 | Exosc8 | 23271 | -0.223 | -0.0031 | Yes |
| 189 | Rpa3 | 23274 | -0.223 | 0.0089 | Yes |
| 190 | Rpa2 | 23375 | -0.228 | 0.0175 | Yes |
| 191 | Cks1b | 23503 | -0.233 | 0.0255 | Yes |
| 192 | Cdkn2a | 23521 | -0.234 | 0.0375 | Yes |
| 193 | Myc | 23524 | -0.235 | 0.0500 | Yes |
| 194 | Ccnb2 | 24285 | -0.269 | 0.0368 | Yes |
| 195 | Hmga1b | 25108 | -0.313 | 0.0236 | Yes |
| 196 | Tubb5 | 25514 | -0.340 | 0.0272 | Yes |
| 197 | Prdx4 | 25861 | -0.369 | 0.0344 | Yes |
| 198 | Cdc20 | 27095 | -0.540 | 0.0185 | Yes |

