| Dataset | MEP.MEP.ery_Pheno.cls #Group6_versus_Group8.MEP.ery_Pheno.cls #Group6_versus_Group8_repos |
| Phenotype | MEP.ery_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_COMPLEMENT |
| Enrichment Score (ES) | -0.19366868 |
| Normalized Enrichment Score (NES) | -0.7898598 |
| Nominal p-value | 0.83095723 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.993 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Mmp13 | 91 | 0.924 | 0.0244 | Yes |
| 2 | Col4a2 | 115 | 0.887 | 0.0502 | Yes |
| 3 | C3 | 158 | 0.847 | 0.0741 | Yes |
| 4 | Fn1 | 471 | 0.663 | 0.0826 | Yes |
| 5 | Fcnb | 539 | 0.644 | 0.0995 | Yes |
| 6 | Plaur | 573 | 0.633 | 0.1173 | Yes |
| 7 | Cfb | 1023 | 0.535 | 0.1170 | Yes |
| 8 | Cdk5r1 | 1118 | 0.520 | 0.1292 | Yes |
| 9 | Me1 | 1408 | 0.486 | 0.1333 | Yes |
| 10 | Prss36 | 1779 | 0.443 | 0.1331 | Yes |
| 11 | Mmp15 | 2203 | 0.404 | 0.1298 | Yes |
| 12 | Spock2 | 2330 | 0.394 | 0.1370 | Yes |
| 13 | Maff | 2693 | 0.366 | 0.1348 | Yes |
| 14 | Kcnip3 | 3098 | 0.337 | 0.1302 | Yes |
| 15 | Cdh13 | 3210 | 0.328 | 0.1360 | Yes |
| 16 | Fcer1g | 3233 | 0.327 | 0.1450 | Yes |
| 17 | Serpinb2 | 3484 | 0.309 | 0.1452 | Yes |
| 18 | Cebpb | 3582 | 0.303 | 0.1507 | Yes |
| 19 | Gng2 | 3847 | 0.288 | 0.1497 | Yes |
| 20 | Dock4 | 3896 | 0.285 | 0.1565 | Yes |
| 21 | Cda | 3963 | 0.282 | 0.1626 | Yes |
| 22 | Zfpm2 | 3995 | 0.280 | 0.1699 | Yes |
| 23 | Cr2 | 4001 | 0.279 | 0.1781 | Yes |
| 24 | Pcsk9 | 4080 | 0.275 | 0.1835 | Yes |
| 25 | F2 | 4150 | 0.271 | 0.1891 | Yes |
| 26 | Lck | 4384 | 0.258 | 0.1883 | Yes |
| 27 | Tfpi2 | 4503 | 0.252 | 0.1916 | Yes |
| 28 | Scg3 | 5158 | 0.223 | 0.1745 | No |
| 29 | Src | 5250 | 0.219 | 0.1777 | No |
| 30 | Lcp2 | 5393 | 0.214 | 0.1790 | No |
| 31 | Hnf4a | 5855 | 0.196 | 0.1680 | No |
| 32 | Gzmk | 6538 | 0.172 | 0.1483 | No |
| 33 | Lrp1 | 6760 | 0.164 | 0.1452 | No |
| 34 | Clu | 6777 | 0.164 | 0.1495 | No |
| 35 | Xpnpep1 | 7231 | 0.149 | 0.1375 | No |
| 36 | Psen1 | 7332 | 0.146 | 0.1382 | No |
| 37 | Kcnip2 | 7909 | 0.129 | 0.1211 | No |
| 38 | Brpf3 | 7917 | 0.129 | 0.1247 | No |
| 39 | Cpm | 8171 | 0.123 | 0.1192 | No |
| 40 | Pla2g7 | 8550 | 0.113 | 0.1088 | No |
| 41 | Vcpip1 | 8593 | 0.112 | 0.1106 | No |
| 42 | Prdm4 | 8659 | 0.110 | 0.1115 | No |
| 43 | Hspa1a | 8713 | 0.108 | 0.1129 | No |
| 44 | Itgam | 8916 | 0.103 | 0.1086 | No |
| 45 | Gp9 | 9025 | 0.101 | 0.1077 | No |
| 46 | Raf1 | 9072 | 0.100 | 0.1090 | No |
| 47 | Fyn | 9091 | 0.099 | 0.1113 | No |
| 48 | Pla2g4a | 9400 | 0.092 | 0.1029 | No |
| 49 | F8 | 9624 | 0.087 | 0.0973 | No |
| 50 | Prep | 9651 | 0.087 | 0.0990 | No |
| 51 | Phex | 9810 | 0.083 | 0.0957 | No |
| 52 | Csrp1 | 9917 | 0.081 | 0.0943 | No |
| 53 | Usp8 | 9964 | 0.079 | 0.0950 | No |
| 54 | Cd40lg | 10024 | 0.078 | 0.0952 | No |
| 55 | Kynu | 10115 | 0.076 | 0.0942 | No |
| 56 | Plscr1 | 10552 | 0.068 | 0.0803 | No |
| 57 | Casp7 | 10623 | 0.066 | 0.0798 | No |
| 58 | Sh2b3 | 10824 | 0.062 | 0.0744 | No |
| 59 | Pdp1 | 10902 | 0.061 | 0.0734 | No |
| 60 | Usp15 | 10965 | 0.060 | 0.0729 | No |
| 61 | Plek | 11005 | 0.059 | 0.0733 | No |
| 62 | Olr1 | 11014 | 0.059 | 0.0747 | No |
| 63 | Ctso | 11636 | 0.047 | 0.0535 | No |
| 64 | Gpd2 | 11694 | 0.046 | 0.0528 | No |
| 65 | Dyrk2 | 11846 | 0.043 | 0.0486 | No |
| 66 | Ppp2cb | 12032 | 0.039 | 0.0430 | No |
| 67 | Gzmb | 12052 | 0.039 | 0.0435 | No |
| 68 | Grb2 | 12138 | 0.037 | 0.0415 | No |
| 69 | Dock9 | 12632 | 0.028 | 0.0244 | No |
| 70 | Pik3ca | 12855 | 0.024 | 0.0170 | No |
| 71 | Pik3r5 | 13011 | 0.021 | 0.0120 | No |
| 72 | Timp1 | 13352 | 0.015 | 0.0000 | No |
| 73 | Cblb | 13561 | 0.011 | -0.0072 | No |
| 74 | Tmprss6 | 13649 | 0.009 | -0.0101 | No |
| 75 | Kif2a | 13704 | 0.008 | -0.0118 | No |
| 76 | Akap10 | 13789 | 0.007 | -0.0147 | No |
| 77 | Irf2 | 13874 | 0.005 | -0.0176 | No |
| 78 | Tnfaip3 | 14306 | -0.000 | -0.0333 | No |
| 79 | Lyn | 14709 | -0.007 | -0.0477 | No |
| 80 | Cd46 | 14727 | -0.008 | -0.0481 | No |
| 81 | Dusp5 | 14744 | -0.008 | -0.0485 | No |
| 82 | Pdgfb | 15115 | -0.015 | -0.0615 | No |
| 83 | Dgkg | 15175 | -0.016 | -0.0632 | No |
| 84 | Prkcd | 15513 | -0.022 | -0.0748 | No |
| 85 | Actn2 | 15589 | -0.023 | -0.0769 | No |
| 86 | F3 | 15702 | -0.026 | -0.0802 | No |
| 87 | Pik3cg | 15930 | -0.030 | -0.0876 | No |
| 88 | Gnai3 | 16043 | -0.032 | -0.0907 | No |
| 89 | Zeb1 | 16354 | -0.038 | -0.1009 | No |
| 90 | C9 | 16390 | -0.038 | -0.1010 | No |
| 91 | Cpq | 16607 | -0.043 | -0.1076 | No |
| 92 | Serpine1 | 16731 | -0.045 | -0.1107 | No |
| 93 | Rbsn | 16753 | -0.046 | -0.1101 | No |
| 94 | Lta4h | 16786 | -0.046 | -0.1099 | No |
| 95 | Ctsb | 16857 | -0.048 | -0.1110 | No |
| 96 | Dpp4 | 16902 | -0.048 | -0.1111 | No |
| 97 | Pim1 | 16904 | -0.049 | -0.1097 | No |
| 98 | Atox1 | 17013 | -0.051 | -0.1121 | No |
| 99 | C1s1 | 17030 | -0.051 | -0.1111 | No |
| 100 | Casp9 | 17194 | -0.055 | -0.1154 | No |
| 101 | Casp1 | 17264 | -0.056 | -0.1163 | No |
| 102 | Prcp | 17425 | -0.059 | -0.1203 | No |
| 103 | Usp16 | 17467 | -0.060 | -0.1200 | No |
| 104 | Rabif | 17510 | -0.061 | -0.1197 | No |
| 105 | Fdx1 | 17550 | -0.062 | -0.1193 | No |
| 106 | Dusp6 | 17610 | -0.063 | -0.1196 | No |
| 107 | Gngt2 | 17629 | -0.063 | -0.1183 | No |
| 108 | Dock10 | 18033 | -0.072 | -0.1309 | No |
| 109 | Ctsc | 18045 | -0.073 | -0.1291 | No |
| 110 | Il6 | 18091 | -0.074 | -0.1285 | No |
| 111 | Anxa5 | 18227 | -0.076 | -0.1311 | No |
| 112 | Usp14 | 18294 | -0.078 | -0.1312 | No |
| 113 | Lipa | 18628 | -0.086 | -0.1408 | No |
| 114 | Gca | 18762 | -0.089 | -0.1429 | No |
| 115 | Rasgrp1 | 18989 | -0.094 | -0.1484 | No |
| 116 | Rhog | 19598 | -0.109 | -0.1672 | No |
| 117 | Timp2 | 19653 | -0.111 | -0.1659 | No |
| 118 | Adam9 | 19677 | -0.111 | -0.1634 | No |
| 119 | Jak2 | 19871 | -0.115 | -0.1670 | No |
| 120 | Lap3 | 19998 | -0.118 | -0.1680 | No |
| 121 | Gnai2 | 20066 | -0.119 | -0.1669 | No |
| 122 | Msrb1 | 20072 | -0.120 | -0.1635 | No |
| 123 | F10 | 20233 | -0.123 | -0.1656 | No |
| 124 | Hspa5 | 20259 | -0.124 | -0.1628 | No |
| 125 | Was | 20274 | -0.124 | -0.1596 | No |
| 126 | Ppp4c | 20326 | -0.126 | -0.1577 | No |
| 127 | Gmfb | 20406 | -0.128 | -0.1567 | No |
| 128 | Rnf4 | 20446 | -0.129 | -0.1543 | No |
| 129 | Lgals3 | 20896 | -0.142 | -0.1664 | No |
| 130 | L3mbtl4 | 21213 | -0.151 | -0.1734 | No |
| 131 | Ctsd | 21239 | -0.152 | -0.1697 | No |
| 132 | S100a13 | 21897 | -0.173 | -0.1885 | No |
| 133 | Stx4a | 21923 | -0.174 | -0.1841 | No |
| 134 | Gnb4 | 22171 | -0.181 | -0.1877 | No |
| 135 | Gp1ba | 22244 | -0.184 | -0.1848 | No |
| 136 | Pfn1 | 22343 | -0.188 | -0.1828 | No |
| 137 | Casp3 | 22398 | -0.190 | -0.1790 | No |
| 138 | Plg | 22411 | -0.190 | -0.1738 | No |
| 139 | Calm3 | 22457 | -0.192 | -0.1696 | No |
| 140 | Lamp2 | 22546 | -0.196 | -0.1670 | No |
| 141 | Pclo | 22617 | -0.198 | -0.1636 | No |
| 142 | Mmp8 | 22666 | -0.200 | -0.1593 | No |
| 143 | Casp4 | 22935 | -0.210 | -0.1628 | No |
| 144 | Ehd1 | 23095 | -0.216 | -0.1621 | No |
| 145 | Sirt6 | 23155 | -0.219 | -0.1577 | No |
| 146 | Rce1 | 23262 | -0.223 | -0.1549 | No |
| 147 | Ccl5 | 23346 | -0.226 | -0.1511 | No |
| 148 | C2 | 23415 | -0.230 | -0.1467 | No |
| 149 | Dgkh | 23473 | -0.232 | -0.1418 | No |
| 150 | Cfh | 23539 | -0.235 | -0.1371 | No |
| 151 | Car2 | 23563 | -0.236 | -0.1308 | No |
| 152 | Cp | 23637 | -0.240 | -0.1263 | No |
| 153 | F7 | 24011 | -0.256 | -0.1322 | No |
| 154 | Mmp14 | 24018 | -0.257 | -0.1247 | No |
| 155 | Lgmn | 24074 | -0.259 | -0.1189 | No |
| 156 | C1qa | 24640 | -0.286 | -0.1309 | No |
| 157 | F5 | 24935 | -0.302 | -0.1326 | No |
| 158 | Calm1 | 24955 | -0.303 | -0.1242 | No |
| 159 | Cd36 | 24959 | -0.304 | -0.1152 | No |
| 160 | C1qc | 24977 | -0.305 | -0.1066 | No |
| 161 | Serpinc1 | 25243 | -0.321 | -0.1067 | No |
| 162 | Psmb9 | 25446 | -0.335 | -0.1040 | No |
| 163 | Klkb1 | 25678 | -0.353 | -0.1018 | No |
| 164 | S100a9 | 25727 | -0.356 | -0.0928 | No |
| 165 | Gnb2 | 25868 | -0.370 | -0.0868 | No |
| 166 | Irf7 | 26071 | -0.386 | -0.0826 | No |
| 167 | Gata3 | 26255 | -0.406 | -0.0771 | No |
| 168 | Serping1 | 26444 | -0.428 | -0.0711 | No |
| 169 | Plat | 26574 | -0.446 | -0.0624 | No |
| 170 | Ctss | 26902 | -0.495 | -0.0595 | No |
| 171 | Notch4 | 26910 | -0.497 | -0.0448 | No |
| 172 | Irf1 | 27131 | -0.551 | -0.0363 | No |
| 173 | Ctsl | 27135 | -0.552 | -0.0198 | No |
| 174 | Ctsh | 27230 | -0.583 | -0.0057 | No |
| 175 | Ltf | 27367 | -0.642 | 0.0086 | No |

