| Dataset | MEP.MEP.ery_Pheno.cls #Group3_versus_Group4.MEP.ery_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | MEP.ery_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_OXIDATIVE_PHOSPHORYLATION |
| Enrichment Score (ES) | -0.27221724 |
| Normalized Enrichment Score (NES) | -0.86058915 |
| Nominal p-value | 0.5927419 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Mrps22 | 2186 | 0.431 | -0.0593 | No |
| 2 | Retsat | 4062 | 0.306 | -0.1132 | No |
| 3 | Cyc1 | 4071 | 0.305 | -0.0990 | No |
| 4 | Pdha1 | 4414 | 0.295 | -0.0975 | No |
| 5 | Ldhb | 4559 | 0.290 | -0.0891 | No |
| 6 | Pdhx | 4727 | 0.280 | -0.0819 | No |
| 7 | Sdhd | 5676 | 0.240 | -0.1051 | No |
| 8 | Alas1 | 5709 | 0.238 | -0.0950 | No |
| 9 | Hccs | 6207 | 0.224 | -0.1025 | No |
| 10 | Mpc1 | 6357 | 0.216 | -0.0977 | No |
| 11 | Gm10053 | 6424 | 0.216 | -0.0899 | No |
| 12 | Ndufb2 | 7027 | 0.198 | -0.1025 | No |
| 13 | Atp6v0c | 7136 | 0.194 | -0.0973 | No |
| 14 | Atp1b1 | 7149 | 0.193 | -0.0885 | No |
| 15 | Slc25a12 | 7854 | 0.167 | -0.1063 | No |
| 16 | Hadhb | 8069 | 0.161 | -0.1065 | No |
| 17 | Nqo2 | 8207 | 0.155 | -0.1042 | No |
| 18 | Atp6v1g1 | 8248 | 0.153 | -0.0984 | No |
| 19 | Cox10 | 8546 | 0.144 | -0.1024 | No |
| 20 | Dld | 8715 | 0.139 | -0.1019 | No |
| 21 | Maob | 8951 | 0.131 | -0.1043 | No |
| 22 | Gpi1 | 9342 | 0.119 | -0.1128 | No |
| 23 | Dlat | 9365 | 0.118 | -0.1080 | No |
| 24 | Acat1 | 9575 | 0.111 | -0.1104 | No |
| 25 | Cs | 9852 | 0.104 | -0.1155 | No |
| 26 | Bax | 9979 | 0.100 | -0.1154 | No |
| 27 | Pdp1 | 10129 | 0.096 | -0.1163 | No |
| 28 | Tomm70a | 10427 | 0.090 | -0.1228 | No |
| 29 | Timm50 | 10443 | 0.089 | -0.1192 | No |
| 30 | Atp6ap1 | 10453 | 0.089 | -0.1153 | No |
| 31 | Sdha | 10621 | 0.084 | -0.1173 | No |
| 32 | Mtrf1 | 10672 | 0.083 | -0.1152 | No |
| 33 | Lrpprc | 10797 | 0.080 | -0.1159 | No |
| 34 | Immt | 11088 | 0.073 | -0.1231 | No |
| 35 | Hspa9 | 11286 | 0.068 | -0.1271 | No |
| 36 | Atp6v1c1 | 11540 | 0.060 | -0.1334 | No |
| 37 | Ndufs4 | 11983 | 0.048 | -0.1472 | No |
| 38 | Ldha | 12007 | 0.048 | -0.1458 | No |
| 39 | Ndufa7 | 12031 | 0.047 | -0.1444 | No |
| 40 | Ogdh | 12146 | 0.044 | -0.1465 | No |
| 41 | Uqcrc2 | 12423 | 0.037 | -0.1548 | No |
| 42 | Sucla2 | 12434 | 0.037 | -0.1534 | No |
| 43 | Opa1 | 12705 | 0.030 | -0.1618 | No |
| 44 | Mtrr | 12709 | 0.030 | -0.1605 | No |
| 45 | Oxa1l | 12773 | 0.028 | -0.1615 | No |
| 46 | Dlst | 12778 | 0.028 | -0.1603 | No |
| 47 | Mrpl35 | 12803 | 0.027 | -0.1599 | No |
| 48 | Fxn | 12902 | 0.025 | -0.1623 | No |
| 49 | Bdh2 | 12934 | 0.024 | -0.1622 | No |
| 50 | Uqcrfs1 | 13015 | 0.022 | -0.1641 | No |
| 51 | Slc25a5 | 13159 | 0.019 | -0.1684 | No |
| 52 | Pmpca | 13180 | 0.019 | -0.1683 | No |
| 53 | Cox15 | 13189 | 0.018 | -0.1677 | No |
| 54 | Ndufb5 | 13249 | 0.017 | -0.1690 | No |
| 55 | Ndufs2 | 13300 | 0.016 | -0.1701 | No |
| 56 | Ndufv1 | 13389 | 0.013 | -0.1727 | No |
| 57 | Atp6v1f | 13422 | 0.013 | -0.1733 | No |
| 58 | Cyb5r3 | 13585 | 0.012 | -0.1786 | No |
| 59 | Timm9 | 13823 | 0.006 | -0.1870 | No |
| 60 | Vdac3 | 13846 | 0.006 | -0.1875 | No |
| 61 | Uqcr10 | 14098 | 0.000 | -0.1966 | No |
| 62 | Atp6v1d | 14875 | -0.001 | -0.2249 | No |
| 63 | Atp6v0e | 14926 | -0.003 | -0.2266 | No |
| 64 | Acaa2 | 14935 | -0.003 | -0.2267 | No |
| 65 | Tcirg1 | 14956 | -0.003 | -0.2273 | No |
| 66 | Afg3l2 | 15064 | -0.006 | -0.2309 | No |
| 67 | Idh2 | 15075 | -0.006 | -0.2310 | No |
| 68 | Timm13 | 15217 | -0.010 | -0.2357 | No |
| 69 | Ndufc2 | 15251 | -0.010 | -0.2364 | No |
| 70 | Timm10 | 15389 | -0.012 | -0.2408 | No |
| 71 | Ndufa5 | 15462 | -0.014 | -0.2428 | No |
| 72 | Cox6b1 | 15545 | -0.016 | -0.2450 | No |
| 73 | Mfn2 | 15588 | -0.017 | -0.2458 | No |
| 74 | Aco2 | 15634 | -0.017 | -0.2466 | No |
| 75 | Ndufa8 | 15811 | -0.022 | -0.2519 | No |
| 76 | Polr2f | 16093 | -0.029 | -0.2608 | No |
| 77 | Vdac2 | 16250 | -0.034 | -0.2649 | No |
| 78 | Ndufb8 | 16253 | -0.034 | -0.2634 | No |
| 79 | Cox7a2 | 16278 | -0.034 | -0.2626 | No |
| 80 | Aifm1 | 16317 | -0.036 | -0.2623 | No |
| 81 | Cox4i1 | 16507 | -0.040 | -0.2673 | No |
| 82 | Htra2 | 16517 | -0.040 | -0.2657 | No |
| 83 | Idh3g | 16679 | -0.045 | -0.2695 | No |
| 84 | Echs1 | 16755 | -0.047 | -0.2700 | Yes |
| 85 | Uqcrq | 16772 | -0.047 | -0.2684 | Yes |
| 86 | Mdh2 | 16832 | -0.048 | -0.2682 | Yes |
| 87 | Mtx2 | 16874 | -0.049 | -0.2674 | Yes |
| 88 | Rhot1 | 16922 | -0.050 | -0.2667 | Yes |
| 89 | Sdhb | 16969 | -0.051 | -0.2660 | Yes |
| 90 | Nnt | 16977 | -0.052 | -0.2638 | Yes |
| 91 | Mrps11 | 16987 | -0.052 | -0.2616 | Yes |
| 92 | Mrpl34 | 17108 | -0.055 | -0.2634 | Yes |
| 93 | Casp7 | 17168 | -0.057 | -0.2628 | Yes |
| 94 | Vdac1 | 17209 | -0.058 | -0.2615 | Yes |
| 95 | Atp6v1h | 17211 | -0.058 | -0.2588 | Yes |
| 96 | Acadvl | 17334 | -0.062 | -0.2604 | Yes |
| 97 | Cox11 | 17405 | -0.064 | -0.2599 | Yes |
| 98 | Atp5pb | 17434 | -0.064 | -0.2579 | Yes |
| 99 | Idh3a | 17482 | -0.065 | -0.2565 | Yes |
| 100 | Abcb7 | 17516 | -0.066 | -0.2546 | Yes |
| 101 | Acadsb | 17625 | -0.067 | -0.2553 | Yes |
| 102 | Rhot2 | 17778 | -0.071 | -0.2575 | Yes |
| 103 | Decr1 | 17787 | -0.072 | -0.2544 | Yes |
| 104 | Eci1 | 17805 | -0.072 | -0.2516 | Yes |
| 105 | Ndufs6 | 17886 | -0.074 | -0.2510 | Yes |
| 106 | Phb2 | 17917 | -0.075 | -0.2485 | Yes |
| 107 | Sdhc | 17980 | -0.076 | -0.2472 | Yes |
| 108 | Uqcrb | 18010 | -0.078 | -0.2446 | Yes |
| 109 | Suclg1 | 18048 | -0.078 | -0.2422 | Yes |
| 110 | Fh1 | 18064 | -0.079 | -0.2390 | Yes |
| 111 | Por | 18128 | -0.080 | -0.2375 | Yes |
| 112 | Cyb5a | 18167 | -0.081 | -0.2350 | Yes |
| 113 | Ndufs1 | 18185 | -0.082 | -0.2318 | Yes |
| 114 | Atp6v0b | 18284 | -0.084 | -0.2314 | Yes |
| 115 | Surf1 | 18342 | -0.086 | -0.2294 | Yes |
| 116 | Oat | 18387 | -0.087 | -0.2269 | Yes |
| 117 | Mrps30 | 18507 | -0.090 | -0.2270 | Yes |
| 118 | Ndufa9 | 18523 | -0.090 | -0.2233 | Yes |
| 119 | Cox17 | 18603 | -0.092 | -0.2218 | Yes |
| 120 | Mrpl15 | 18654 | -0.094 | -0.2192 | Yes |
| 121 | Tomm22 | 18691 | -0.095 | -0.2160 | Yes |
| 122 | Mrpl11 | 18703 | -0.095 | -0.2119 | Yes |
| 123 | Ndufa4 | 18769 | -0.097 | -0.2096 | Yes |
| 124 | Ndufb7 | 18794 | -0.097 | -0.2059 | Yes |
| 125 | Cox8a | 18822 | -0.098 | -0.2022 | Yes |
| 126 | Mgst3 | 18898 | -0.100 | -0.2002 | Yes |
| 127 | Cox5a | 18935 | -0.101 | -0.1968 | Yes |
| 128 | Idh3b | 18936 | -0.101 | -0.1920 | Yes |
| 129 | Slc25a3 | 18962 | -0.102 | -0.1881 | Yes |
| 130 | Pdhb | 18972 | -0.102 | -0.1835 | Yes |
| 131 | Ndufs7 | 18989 | -0.103 | -0.1793 | Yes |
| 132 | Cox7b | 19147 | -0.107 | -0.1799 | Yes |
| 133 | Got2 | 19268 | -0.111 | -0.1790 | Yes |
| 134 | Hadha | 19329 | -0.113 | -0.1759 | Yes |
| 135 | Uqcr11 | 19477 | -0.116 | -0.1757 | Yes |
| 136 | Cox5b | 19510 | -0.117 | -0.1714 | Yes |
| 137 | Etfa | 19541 | -0.118 | -0.1669 | Yes |
| 138 | Timm17a | 19566 | -0.119 | -0.1621 | Yes |
| 139 | Glud1 | 19575 | -0.119 | -0.1568 | Yes |
| 140 | Ndufb6 | 19686 | -0.123 | -0.1549 | Yes |
| 141 | Ndufb3 | 19782 | -0.125 | -0.1525 | Yes |
| 142 | Ech1 | 19911 | -0.129 | -0.1511 | Yes |
| 143 | Uqcrc1 | 19969 | -0.131 | -0.1469 | Yes |
| 144 | Mrps12 | 20052 | -0.134 | -0.1436 | Yes |
| 145 | Uqcrh | 20129 | -0.137 | -0.1399 | Yes |
| 146 | Slc25a4 | 20726 | -0.155 | -0.1543 | Yes |
| 147 | Ndufa1 | 20814 | -0.158 | -0.1500 | Yes |
| 148 | Idh1 | 20836 | -0.159 | -0.1432 | Yes |
| 149 | Cox7c | 20860 | -0.159 | -0.1365 | Yes |
| 150 | Grpel1 | 20987 | -0.163 | -0.1334 | Yes |
| 151 | Ndufab1 | 21021 | -0.165 | -0.1268 | Yes |
| 152 | Supv3l1 | 21058 | -0.166 | -0.1202 | Yes |
| 153 | Hsd17b10 | 21060 | -0.166 | -0.1124 | Yes |
| 154 | Gpx4 | 21072 | -0.166 | -0.1049 | Yes |
| 155 | AK157302 | 21204 | -0.171 | -0.1016 | Yes |
| 156 | Timm8b | 21447 | -0.180 | -0.1019 | Yes |
| 157 | Ndufs8 | 21469 | -0.180 | -0.0941 | Yes |
| 158 | Acadm | 21549 | -0.183 | -0.0883 | Yes |
| 159 | Ndufv2 | 21561 | -0.184 | -0.0800 | Yes |
| 160 | Acaa1a | 21607 | -0.185 | -0.0729 | Yes |
| 161 | Etfb | 21713 | -0.189 | -0.0678 | Yes |
| 162 | Ndufa2 | 21824 | -0.194 | -0.0626 | Yes |
| 163 | Iscu | 22164 | -0.206 | -0.0652 | Yes |
| 164 | Prdx3 | 22905 | -0.226 | -0.0814 | Yes |
| 165 | Ndufs3 | 23014 | -0.232 | -0.0744 | Yes |
| 166 | Cox7a2l | 23078 | -0.234 | -0.0656 | Yes |
| 167 | Mdh1 | 23275 | -0.243 | -0.0612 | Yes |
| 168 | Aldh6a1 | 23452 | -0.250 | -0.0558 | Yes |
| 169 | Ndufa3 | 23587 | -0.257 | -0.0485 | Yes |
| 170 | Etfdh | 23857 | -0.263 | -0.0459 | Yes |
| 171 | Slc25a20 | 23881 | -0.264 | -0.0342 | Yes |
| 172 | Ndufc1 | 24025 | -0.271 | -0.0266 | Yes |
| 173 | Cox6a1 | 24071 | -0.273 | -0.0153 | Yes |
| 174 | Mrps15 | 24222 | -0.282 | -0.0074 | Yes |
| 175 | Cox6c | 24242 | -0.283 | 0.0054 | Yes |
| 176 | Ndufa6 | 24403 | -0.291 | 0.0133 | Yes |
| 177 | Phyh | 24637 | -0.303 | 0.0192 | Yes |
| 178 | Atp6v1e1 | 25019 | -0.319 | 0.0204 | Yes |
| 179 | Fdx1 | 25412 | -0.348 | 0.0226 | Yes |
| 180 | Slc25a11 | 25653 | -0.366 | 0.0312 | Yes |
| 181 | Bckdha | 25669 | -0.367 | 0.0481 | Yes |
| 182 | Cpt1a | 26765 | -0.473 | 0.0305 | Yes |

