| Dataset | MEP.MEP.ery_Pheno.cls #Group3_versus_Group4.MEP.ery_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | MEP.ery_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_APICAL_JUNCTION |
| Enrichment Score (ES) | 0.2706966 |
| Normalized Enrichment Score (NES) | 1.1063291 |
| Nominal p-value | 0.30628803 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.991 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Adam23 | 46 | 1.138 | 0.0245 | Yes |
| 2 | Insig1 | 116 | 0.919 | 0.0431 | Yes |
| 3 | Cdh3 | 176 | 0.854 | 0.0607 | Yes |
| 4 | Mapk13 | 288 | 0.775 | 0.0744 | Yes |
| 5 | Thbs3 | 484 | 0.686 | 0.0831 | Yes |
| 6 | Cldn11 | 754 | 0.618 | 0.0875 | Yes |
| 7 | Tspan4 | 894 | 0.589 | 0.0960 | Yes |
| 8 | Nrap | 901 | 0.589 | 0.1094 | Yes |
| 9 | Shroom2 | 1041 | 0.565 | 0.1173 | Yes |
| 10 | Flnc | 1085 | 0.555 | 0.1285 | Yes |
| 11 | Evl | 1160 | 0.539 | 0.1382 | Yes |
| 12 | Mapk11 | 1241 | 0.527 | 0.1474 | Yes |
| 13 | Atp1a3 | 1469 | 0.499 | 0.1507 | Yes |
| 14 | Dsc3 | 1585 | 0.488 | 0.1577 | Yes |
| 15 | Icam4 | 1706 | 0.473 | 0.1642 | Yes |
| 16 | Nexn | 1863 | 0.463 | 0.1692 | Yes |
| 17 | Sdc3 | 1874 | 0.461 | 0.1794 | Yes |
| 18 | Cdh4 | 1887 | 0.460 | 0.1896 | Yes |
| 19 | Cldn15 | 2013 | 0.442 | 0.1952 | Yes |
| 20 | Cldn7 | 2082 | 0.434 | 0.2027 | Yes |
| 21 | Nfasc | 2314 | 0.422 | 0.2040 | Yes |
| 22 | Ppp2r2c | 2401 | 0.420 | 0.2105 | Yes |
| 23 | Myl9 | 2744 | 0.398 | 0.2072 | Yes |
| 24 | Adra1b | 2790 | 0.394 | 0.2147 | Yes |
| 25 | Negr1 | 2934 | 0.387 | 0.2184 | Yes |
| 26 | Cadm3 | 3143 | 0.369 | 0.2193 | Yes |
| 27 | Adam15 | 3176 | 0.367 | 0.2265 | Yes |
| 28 | Cdh11 | 3443 | 0.346 | 0.2248 | Yes |
| 29 | Pcdh1 | 3470 | 0.345 | 0.2318 | Yes |
| 30 | Rhof | 3663 | 0.334 | 0.2325 | Yes |
| 31 | Pik3r3 | 3712 | 0.330 | 0.2383 | Yes |
| 32 | Acta1 | 3784 | 0.326 | 0.2432 | Yes |
| 33 | Nectin3 | 3940 | 0.315 | 0.2448 | Yes |
| 34 | Cd34 | 4127 | 0.300 | 0.2449 | Yes |
| 35 | Col9a1 | 4133 | 0.300 | 0.2517 | Yes |
| 36 | Tmem8b | 4334 | 0.299 | 0.2513 | Yes |
| 37 | Cd86 | 4395 | 0.296 | 0.2559 | Yes |
| 38 | Mmp9 | 4454 | 0.292 | 0.2605 | Yes |
| 39 | Egfr | 4608 | 0.286 | 0.2615 | Yes |
| 40 | Actn2 | 4890 | 0.274 | 0.2576 | Yes |
| 41 | Cdh15 | 5063 | 0.265 | 0.2574 | Yes |
| 42 | Mpzl2 | 5064 | 0.265 | 0.2635 | Yes |
| 43 | Sirpa | 5365 | 0.254 | 0.2584 | Yes |
| 44 | Actn4 | 5565 | 0.245 | 0.2568 | Yes |
| 45 | Lamb3 | 5569 | 0.245 | 0.2623 | Yes |
| 46 | Actb | 5670 | 0.240 | 0.2642 | Yes |
| 47 | Src | 5746 | 0.236 | 0.2669 | Yes |
| 48 | Myh9 | 5847 | 0.233 | 0.2686 | Yes |
| 49 | Vav2 | 5934 | 0.228 | 0.2707 | Yes |
| 50 | Crat | 6143 | 0.227 | 0.2683 | No |
| 51 | Dsc1 | 6409 | 0.216 | 0.2636 | No |
| 52 | Actn1 | 6645 | 0.213 | 0.2600 | No |
| 53 | Wnk4 | 6832 | 0.205 | 0.2579 | No |
| 54 | Cercam | 6902 | 0.203 | 0.2601 | No |
| 55 | Itgb4 | 6966 | 0.200 | 0.2624 | No |
| 56 | Msn | 7206 | 0.192 | 0.2581 | No |
| 57 | Pten | 7325 | 0.187 | 0.2581 | No |
| 58 | Baiap2 | 7403 | 0.184 | 0.2595 | No |
| 59 | Kcnh2 | 7600 | 0.177 | 0.2564 | No |
| 60 | Cdk8 | 7676 | 0.174 | 0.2577 | No |
| 61 | Lima1 | 8240 | 0.153 | 0.2407 | No |
| 62 | Icam1 | 8360 | 0.149 | 0.2398 | No |
| 63 | Tgfbi | 8408 | 0.148 | 0.2415 | No |
| 64 | Pkd1 | 8459 | 0.147 | 0.2430 | No |
| 65 | Tjp1 | 8695 | 0.139 | 0.2377 | No |
| 66 | Ptk2 | 8698 | 0.139 | 0.2408 | No |
| 67 | Hras | 8903 | 0.132 | 0.2364 | No |
| 68 | Slc30a3 | 9072 | 0.127 | 0.2332 | No |
| 69 | Pik3cb | 9096 | 0.126 | 0.2353 | No |
| 70 | Vcam1 | 9180 | 0.124 | 0.2351 | No |
| 71 | Ctnnd1 | 9250 | 0.122 | 0.2354 | No |
| 72 | Mapk14 | 9352 | 0.119 | 0.2345 | No |
| 73 | Itga3 | 9534 | 0.113 | 0.2305 | No |
| 74 | Map3k20 | 9746 | 0.107 | 0.2252 | No |
| 75 | Traf1 | 9886 | 0.103 | 0.2225 | No |
| 76 | Cntn1 | 10526 | 0.087 | 0.2012 | No |
| 77 | Shc1 | 10600 | 0.085 | 0.2005 | No |
| 78 | Nectin2 | 10604 | 0.085 | 0.2023 | No |
| 79 | Calb2 | 10689 | 0.083 | 0.2012 | No |
| 80 | Pard6g | 10875 | 0.078 | 0.1962 | No |
| 81 | Vcl | 10996 | 0.075 | 0.1936 | No |
| 82 | Akt2 | 11086 | 0.073 | 0.1920 | No |
| 83 | Thy1 | 11292 | 0.068 | 0.1861 | No |
| 84 | Dhx16 | 11409 | 0.064 | 0.1833 | No |
| 85 | Map4k2 | 11556 | 0.060 | 0.1794 | No |
| 86 | Nlgn3 | 11808 | 0.053 | 0.1715 | No |
| 87 | Mpzl1 | 12049 | 0.047 | 0.1638 | No |
| 88 | Epb41l2 | 12135 | 0.045 | 0.1617 | No |
| 89 | Nf1 | 12317 | 0.040 | 0.1560 | No |
| 90 | Lamc2 | 12666 | 0.031 | 0.1440 | No |
| 91 | Fbn1 | 12933 | 0.024 | 0.1349 | No |
| 92 | Ldlrap1 | 13026 | 0.022 | 0.1321 | No |
| 93 | Gtf2f1 | 13132 | 0.019 | 0.1287 | No |
| 94 | Rasa1 | 13142 | 0.019 | 0.1288 | No |
| 95 | Stx4a | 13275 | 0.016 | 0.1243 | No |
| 96 | Exoc4 | 13341 | 0.015 | 0.1223 | No |
| 97 | Pfn1 | 13765 | 0.008 | 0.1071 | No |
| 98 | Alox8 | 13928 | 0.004 | 0.1012 | No |
| 99 | Ctnna1 | 14043 | 0.001 | 0.0971 | No |
| 100 | Nf2 | 14822 | -0.000 | 0.0687 | No |
| 101 | Crb3 | 14955 | -0.003 | 0.0640 | No |
| 102 | Tubg1 | 15027 | -0.005 | 0.0615 | No |
| 103 | Tial1 | 15170 | -0.008 | 0.0565 | No |
| 104 | Wasl | 15263 | -0.011 | 0.0534 | No |
| 105 | Vwf | 15397 | -0.012 | 0.0489 | No |
| 106 | Dlg1 | 15502 | -0.014 | 0.0454 | No |
| 107 | Itgb1 | 15757 | -0.021 | 0.0366 | No |
| 108 | Gamt | 15774 | -0.021 | 0.0365 | No |
| 109 | B4galt1 | 15870 | -0.024 | 0.0336 | No |
| 110 | Cldn18 | 16045 | -0.028 | 0.0279 | No |
| 111 | Rsu1 | 16143 | -0.031 | 0.0251 | No |
| 112 | Cdh8 | 16203 | -0.032 | 0.0237 | No |
| 113 | Cd276 | 16315 | -0.036 | 0.0205 | No |
| 114 | Bmp1 | 16364 | -0.037 | 0.0196 | No |
| 115 | Pals1 | 16466 | -0.039 | 0.0168 | No |
| 116 | Speg | 16855 | -0.049 | 0.0038 | No |
| 117 | Tro | 16990 | -0.052 | 0.0001 | No |
| 118 | Mvd | 17067 | -0.054 | -0.0015 | No |
| 119 | Ikbkg | 17131 | -0.056 | -0.0025 | No |
| 120 | Col16a1 | 17276 | -0.060 | -0.0063 | No |
| 121 | Jam3 | 17730 | -0.070 | -0.0213 | No |
| 122 | Taok2 | 17932 | -0.075 | -0.0269 | No |
| 123 | Actg2 | 18179 | -0.082 | -0.0339 | No |
| 124 | Nrtn | 18459 | -0.089 | -0.0421 | No |
| 125 | Plcg1 | 18571 | -0.091 | -0.0440 | No |
| 126 | Tsc1 | 18680 | -0.095 | -0.0458 | No |
| 127 | Amh | 18903 | -0.100 | -0.0516 | No |
| 128 | Myh10 | 18943 | -0.101 | -0.0507 | No |
| 129 | Col17a1 | 19310 | -0.112 | -0.0614 | No |
| 130 | Myl12b | 19706 | -0.123 | -0.0730 | No |
| 131 | Skap2 | 19787 | -0.125 | -0.0730 | No |
| 132 | Arpc2 | 19909 | -0.129 | -0.0745 | No |
| 133 | Layn | 20134 | -0.137 | -0.0795 | No |
| 134 | Nectin1 | 20180 | -0.138 | -0.0780 | No |
| 135 | Adamts5 | 20237 | -0.140 | -0.0768 | No |
| 136 | Cdh1 | 20321 | -0.143 | -0.0765 | No |
| 137 | Gnai2 | 20737 | -0.156 | -0.0881 | No |
| 138 | Inppl1 | 20766 | -0.156 | -0.0855 | No |
| 139 | Icam2 | 20852 | -0.159 | -0.0849 | No |
| 140 | Ptprc | 20884 | -0.160 | -0.0824 | No |
| 141 | Amigo1 | 20944 | -0.162 | -0.0808 | No |
| 142 | Arhgef6 | 21161 | -0.170 | -0.0848 | No |
| 143 | Slit2 | 21171 | -0.170 | -0.0812 | No |
| 144 | Actn3 | 21183 | -0.170 | -0.0777 | No |
| 145 | Syk | 21319 | -0.175 | -0.0786 | No |
| 146 | Mdk | 21380 | -0.177 | -0.0767 | No |
| 147 | Cx3cl1 | 21412 | -0.178 | -0.0737 | No |
| 148 | Ywhah | 21544 | -0.183 | -0.0743 | No |
| 149 | Rras | 21662 | -0.187 | -0.0743 | No |
| 150 | Actg1 | 21671 | -0.188 | -0.0702 | No |
| 151 | Sympk | 21900 | -0.197 | -0.0740 | No |
| 152 | Cap1 | 22023 | -0.202 | -0.0738 | No |
| 153 | Mmp2 | 22072 | -0.203 | -0.0709 | No |
| 154 | Pbx2 | 22105 | -0.204 | -0.0674 | No |
| 155 | Rac2 | 22144 | -0.205 | -0.0640 | No |
| 156 | Icam5 | 22289 | -0.211 | -0.0644 | No |
| 157 | Cd274 | 22349 | -0.213 | -0.0617 | No |
| 158 | Gnai1 | 22467 | -0.217 | -0.0609 | No |
| 159 | Cnn2 | 22515 | -0.219 | -0.0576 | No |
| 160 | Vasp | 22535 | -0.220 | -0.0532 | No |
| 161 | Sgce | 22873 | -0.225 | -0.0604 | No |
| 162 | Pecam1 | 22994 | -0.230 | -0.0594 | No |
| 163 | Akt3 | 23022 | -0.232 | -0.0551 | No |
| 164 | Nlgn2 | 23242 | -0.241 | -0.0575 | No |
| 165 | Lama3 | 23359 | -0.246 | -0.0561 | No |
| 166 | Amigo2 | 23597 | -0.258 | -0.0588 | No |
| 167 | Adam9 | 23872 | -0.264 | -0.0627 | No |
| 168 | Cldn14 | 24030 | -0.271 | -0.0622 | No |
| 169 | Sorbs3 | 24084 | -0.274 | -0.0578 | No |
| 170 | Fscn1 | 24674 | -0.306 | -0.0723 | No |
| 171 | Itga10 | 25331 | -0.340 | -0.0884 | No |
| 172 | Cadm2 | 25388 | -0.345 | -0.0825 | No |
| 173 | Vcan | 25403 | -0.347 | -0.0750 | No |
| 174 | Cd209b | 25609 | -0.364 | -0.0741 | No |
| 175 | Parva | 25740 | -0.371 | -0.0703 | No |
| 176 | Nectin4 | 25758 | -0.372 | -0.0623 | No |
| 177 | Itga9 | 26299 | -0.423 | -0.0723 | No |
| 178 | Cdh6 | 26460 | -0.437 | -0.0681 | No |
| 179 | Zyx | 26469 | -0.438 | -0.0583 | No |
| 180 | Itga2 | 27087 | -0.532 | -0.0686 | No |
| 181 | Hadh | 27368 | -0.638 | -0.0641 | No |
| 182 | Irs1 | 27497 | -0.744 | -0.0516 | No |
| 183 | Jup | 27567 | -0.895 | -0.0335 | No |
| 184 | Nrxn2 | 27601 | -1.511 | 0.0000 | No |

