Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	MEP.MEP.ery_Pheno.cls #Group2_versus_Group4.MEP.ery_Pheno.cls #Group2_versus_Group4_repos
Phenotype	MEP.ery_Pheno.cls#Group2_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.27275655
Normalized Enrichment Score (NES)	-1.1323965
Nominal p-value	0.3065134
FDR q-value	0.62641215
FWER p-Value	0.959

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Stom	485	0.746	-0.0048	No
2	Cd82	517	0.737	0.0067	No
3	Zfp365	709	0.690	0.0116	No
4	Rad51c	715	0.688	0.0233	No
5	Slc35d1	880	0.645	0.0285	No
6	Nudt15	930	0.637	0.0376	No
7	Plk3	1104	0.607	0.0418	No
8	Hexim1	1112	0.605	0.0520	No
9	Ccp110	1131	0.602	0.0617	No
10	App	1198	0.592	0.0695	No
11	Slc19a2	1346	0.572	0.0740	No
12	Gls2	1527	0.552	0.0769	No
13	Ak1	1559	0.548	0.0852	No
14	Epha2	1728	0.526	0.0882	No
15	Il1a	1854	0.513	0.0924	No
16	S100a4	1960	0.503	0.0973	No
17	Zmat3	2170	0.491	0.0981	No
18	Pvt1	2470	0.461	0.0952	No
19	Tchh	2717	0.444	0.0938	No
20	Hspa4l	2998	0.429	0.0910	No
21	H1f2	3165	0.417	0.0921	No
22	Rhbdf2	3214	0.413	0.0975	No
23	Aen	3385	0.402	0.0982	No
24	Slc7a11	3581	0.392	0.0979	No
25	Upp1	3630	0.388	0.1028	No
26	Tgfa	3798	0.381	0.1033	No
27	Elp1	3840	0.378	0.1083	No
28	Klf4	4061	0.369	0.1066	No
29	Fbxw7	4267	0.356	0.1053	No
30	Rnf19b	4429	0.348	0.1054	No
31	Phlda3	4516	0.346	0.1082	No
32	Fgf13	4575	0.342	0.1120	No
33	Traf4	4589	0.341	0.1174	No
34	Plk2	4795	0.333	0.1157	No
35	Fos	4817	0.332	0.1206	No
36	Rgs16	5405	0.312	0.1046	No
37	Sphk1	5411	0.312	0.1098	No
38	Jun	5456	0.308	0.1135	No
39	Hbegf	5601	0.300	0.1134	No
40	Rb1	5770	0.292	0.1123	No
41	Pcna	6382	0.269	0.0947	No
42	Ei24	6450	0.266	0.0968	No
43	Mxd1	6954	0.241	0.0826	No
44	Osgin1	7026	0.238	0.0841	No
45	Clca2	7089	0.235	0.0859	No
46	Retsat	7172	0.233	0.0870	No
47	Vdr	7188	0.232	0.0904	No
48	Triap1	7312	0.230	0.0899	No
49	Foxo3	7328	0.230	0.0933	No
50	Rap2b	7411	0.226	0.0942	No
51	Polh	7765	0.215	0.0850	No
52	Tsc22d1	8223	0.200	0.0718	No
53	Tspyl2	8742	0.179	0.0560	No
54	Cdh13	8748	0.178	0.0589	No
55	Tnni1	8822	0.176	0.0592	No
56	Cdkn2a	9004	0.169	0.0556	No
57	Tob1	9074	0.166	0.0559	No
58	Nol8	9418	0.158	0.0461	No
59	Csrnp2	9456	0.157	0.0475	No
60	Trib3	9511	0.154	0.0481	No
61	Mdm2	9519	0.154	0.0505	No
62	Mknk2	9522	0.154	0.0531	No
63	Abcc5	9733	0.147	0.0480	No
64	Notch1	10154	0.138	0.0350	No
65	H2ac25	10553	0.123	0.0226	No
66	Gadd45a	10847	0.112	0.0139	No
67	Slc3a2	11051	0.104	0.0083	No
68	Ldhb	11131	0.101	0.0071	No
69	Sfn	11171	0.099	0.0074	No
70	Ada	11176	0.099	0.0090	No
71	Ctsd	11515	0.088	-0.0019	No
72	Wwp1	11586	0.085	-0.0029	No
73	Fam162a	11634	0.084	-0.0032	No
74	Ephx1	11735	0.080	-0.0055	No
75	Rchy1	11771	0.078	-0.0054	No
76	Sesn1	11772	0.078	-0.0041	No
77	Ercc5	11967	0.071	-0.0099	No
78	Cdk5r1	11977	0.071	-0.0090	No
79	Cdkn2aip	12469	0.052	-0.0260	No
80	Hras	12484	0.051	-0.0257	No
81	Ddb2	12533	0.049	-0.0266	No
82	Sp1	12926	0.034	-0.0403	No
83	Apaf1	13064	0.030	-0.0448	No
84	Ctsf	13303	0.022	-0.0531	No
85	Serpinb5	13325	0.021	-0.0535	No
86	Blcap	13860	0.004	-0.0729	No
87	Tm4sf1	14077	0.000	-0.0808	No
88	Klk8	14615	-0.008	-0.1002	No
89	Ppm1d	14707	-0.012	-0.1033	No
90	Pidd1	14713	-0.012	-0.1033	No
91	Rab40c	14716	-0.012	-0.1032	No
92	Kif13b	14845	-0.016	-0.1076	No
93	Cdkn2b	14953	-0.021	-0.1111	No
94	Rad9a	15118	-0.025	-0.1167	No
95	Fuca1	15150	-0.027	-0.1173	No
96	Pdgfa	15217	-0.029	-0.1192	No
97	Irag2	15404	-0.037	-0.1254	No
98	Prkab1	15483	-0.040	-0.1276	No
99	Alox8	15637	-0.045	-0.1324	No
100	Steap3	15806	-0.051	-0.1376	No
101	Hdac3	15867	-0.053	-0.1389	No
102	Rxra	15882	-0.054	-0.1385	No
103	Wrap73	15948	-0.056	-0.1399	No
104	Pmm1	16063	-0.060	-0.1430	No
105	Cdkn1a	16430	-0.073	-0.1551	No
106	Ccng1	16538	-0.076	-0.1577	No
107	Itgb4	16785	-0.085	-0.1652	No
108	Tm7sf3	16806	-0.086	-0.1645	No
109	Ddit4	16943	-0.090	-0.1679	No
110	Cd81	17012	-0.092	-0.1688	No
111	Sat1	17113	-0.097	-0.1707	No
112	Xpc	17179	-0.099	-0.1714	No
113	Sdc1	17266	-0.103	-0.1728	No
114	Tax1bp3	17364	-0.106	-0.1745	No
115	Lif	17411	-0.108	-0.1743	No
116	Perp	17561	-0.112	-0.1778	No
117	Hmox1	17665	-0.116	-0.1796	No
118	Ifi30	17666	-0.116	-0.1776	No
119	Ppp1r15a	17705	-0.117	-0.1769	No
120	Ier5	17848	-0.122	-0.1800	No
121	Dram1	18339	-0.141	-0.1955	No
122	Rps12	18517	-0.147	-0.1994	No
123	Dnttip2	18741	-0.156	-0.2048	No
124	Ddit3	18774	-0.158	-0.2033	No
125	Cgrrf1	18874	-0.159	-0.2042	No
126	Ip6k2	18932	-0.161	-0.2035	No
127	Hint1	19303	-0.175	-0.2139	No
128	Trp63	19317	-0.176	-0.2114	No
129	Rrp8	19380	-0.178	-0.2106	No
130	Trafd1	19382	-0.178	-0.2076	No
131	Ccnk	19445	-0.179	-0.2067	No
132	Pom121	19582	-0.185	-0.2085	No
133	Rpl36	19686	-0.189	-0.2090	No
134	Bax	19887	-0.196	-0.2129	No
135	Plxnb2	19943	-0.197	-0.2116	No
136	H2aj	19986	-0.199	-0.2097	No
137	Mapkapk3	20047	-0.202	-0.2084	No
138	Sec61a1	20276	-0.210	-0.2131	No
139	Trp53	20330	-0.212	-0.2113	No
140	Bmp2	20622	-0.221	-0.2182	No
141	Nupr1	20811	-0.225	-0.2211	No
142	Rps27l	20816	-0.225	-0.2174	No
143	Tpd52l1	20859	-0.226	-0.2150	No
144	Cyfip2	21015	-0.233	-0.2167	No
145	Tprkb	21316	-0.246	-0.2234	No
146	Bak1	21534	-0.256	-0.2269	No
147	Fdxr	21779	-0.264	-0.2312	No
148	Acvr1b	21797	-0.265	-0.2273	No
149	Vwa5a	22064	-0.277	-0.2322	No
150	Atf3	22336	-0.288	-0.2371	No
151	Rpl18	22533	-0.296	-0.2392	No
152	Zfp36l1	22697	-0.303	-0.2399	No
153	Btg2	23080	-0.321	-0.2483	No
154	Iscu	23090	-0.321	-0.2431	No
155	Socs1	23497	-0.342	-0.2520	No
156	Ccnd2	23924	-0.367	-0.2613	No
157	Fas	24240	-0.386	-0.2661	Yes
158	Ier3	24244	-0.386	-0.2596	Yes
159	Tap1	24249	-0.386	-0.2531	Yes
160	Coq8a	24689	-0.413	-0.2620	Yes
161	Prmt2	24895	-0.426	-0.2621	Yes
162	Procr	24963	-0.430	-0.2571	Yes
163	St14	25014	-0.434	-0.2515	Yes
164	Dcxr	25018	-0.434	-0.2441	Yes
165	Eps8l2	25186	-0.448	-0.2425	Yes
166	Abhd4	25317	-0.459	-0.2393	Yes
167	Tnfsf9	25411	-0.467	-0.2347	Yes
168	Ankra2	25422	-0.468	-0.2270	Yes
169	Irak1	25451	-0.470	-0.2199	Yes
170	Rack1	25508	-0.477	-0.2137	Yes
171	Baiap2	25928	-0.518	-0.2201	Yes
172	Jag2	26051	-0.532	-0.2154	Yes
173	Cebpa	26079	-0.534	-0.2071	Yes
174	F2r	26102	-0.537	-0.1987	Yes
175	Casp1	26120	-0.539	-0.1900	Yes
176	Ninj1	26184	-0.545	-0.1829	Yes
177	Vamp8	26221	-0.551	-0.1747	Yes
178	Ccnd3	26324	-0.565	-0.1687	Yes
179	Pitpnc1	26401	-0.577	-0.1616	Yes
180	Dgka	26443	-0.583	-0.1530	Yes
181	Def6	26534	-0.595	-0.1460	Yes
182	Ptpn14	26547	-0.597	-0.1362	Yes
183	Rrad	26616	-0.608	-0.1282	Yes
184	Ralgds	26641	-0.612	-0.1185	Yes
185	Btg1	26729	-0.625	-0.1109	Yes
186	Tgfb1	26829	-0.642	-0.1034	Yes
187	Txnip	26885	-0.656	-0.0941	Yes
188	Abat	27054	-0.695	-0.0883	Yes
189	Gm2a	27105	-0.709	-0.0779	Yes
190	S100a10	27184	-0.733	-0.0681	Yes
191	Ptpre	27220	-0.747	-0.0565	Yes
192	Zbtb16	27239	-0.753	-0.0442	Yes
193	Sertad3	27249	-0.757	-0.0315	Yes
194	Tcn2	27291	-0.774	-0.0196	Yes
195	Ndrg1	27435	-0.851	-0.0102	Yes
196	Mxd4	27525	-0.941	0.0028	Yes