| Dataset | MEP.MEP.ery_Pheno.cls #Group2_versus_Group4.MEP.ery_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | MEP.ery_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | 0.33773586 |
| Normalized Enrichment Score (NES) | 1.1388837 |
| Nominal p-value | 0.38809034 |
| FDR q-value | 0.7885719 |
| FWER p-Value | 0.962 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Bcat1 | 10 | 1.633 | 0.0310 | Yes |
| 2 | Ak4 | 179 | 0.940 | 0.0429 | Yes |
| 3 | Hspd1 | 771 | 0.675 | 0.0343 | Yes |
| 4 | Etf1 | 814 | 0.662 | 0.0455 | Yes |
| 5 | Mcm2 | 842 | 0.654 | 0.0571 | Yes |
| 6 | Sytl2 | 850 | 0.653 | 0.0693 | Yes |
| 7 | Stip1 | 860 | 0.650 | 0.0815 | Yes |
| 8 | Insig1 | 884 | 0.644 | 0.0930 | Yes |
| 9 | Sqle | 886 | 0.644 | 0.1053 | Yes |
| 10 | Me1 | 1036 | 0.621 | 0.1118 | Yes |
| 11 | Abcf2 | 1058 | 0.615 | 0.1229 | Yes |
| 12 | Hspa9 | 1070 | 0.613 | 0.1342 | Yes |
| 13 | Hspa4 | 1088 | 0.609 | 0.1453 | Yes |
| 14 | Stc1 | 1274 | 0.580 | 0.1497 | Yes |
| 15 | Lgmn | 1438 | 0.561 | 0.1545 | Yes |
| 16 | Canx | 1616 | 0.540 | 0.1584 | Yes |
| 17 | Hmbs | 1883 | 0.510 | 0.1585 | Yes |
| 18 | Hspa5 | 1959 | 0.504 | 0.1654 | Yes |
| 19 | Tfrc | 2104 | 0.495 | 0.1697 | Yes |
| 20 | Ccnf | 2151 | 0.492 | 0.1775 | Yes |
| 21 | Hsp90b1 | 2252 | 0.482 | 0.1831 | Yes |
| 22 | Mcm4 | 2311 | 0.477 | 0.1901 | Yes |
| 23 | Bub1 | 2476 | 0.461 | 0.1930 | Yes |
| 24 | Got1 | 2559 | 0.453 | 0.1987 | Yes |
| 25 | Serpinh1 | 2616 | 0.448 | 0.2052 | Yes |
| 26 | Nufip1 | 3056 | 0.424 | 0.1974 | Yes |
| 27 | Cct6a | 3084 | 0.421 | 0.2045 | Yes |
| 28 | Gga2 | 3095 | 0.421 | 0.2122 | Yes |
| 29 | Atp2a2 | 3155 | 0.417 | 0.2180 | Yes |
| 30 | Uso1 | 3231 | 0.412 | 0.2232 | Yes |
| 31 | Acly | 3243 | 0.411 | 0.2307 | Yes |
| 32 | Cdc25a | 3421 | 0.399 | 0.2319 | Yes |
| 33 | Calr | 3477 | 0.398 | 0.2375 | Yes |
| 34 | Slc7a11 | 3581 | 0.392 | 0.2413 | Yes |
| 35 | Cyp51 | 3592 | 0.392 | 0.2485 | Yes |
| 36 | Hmgcr | 3609 | 0.390 | 0.2554 | Yes |
| 37 | Ero1a | 3639 | 0.388 | 0.2618 | Yes |
| 38 | Plk1 | 3649 | 0.388 | 0.2689 | Yes |
| 39 | Acsl3 | 3737 | 0.384 | 0.2731 | Yes |
| 40 | Rrm2 | 3779 | 0.383 | 0.2789 | Yes |
| 41 | Actr2 | 3811 | 0.380 | 0.2851 | Yes |
| 42 | Edem1 | 4258 | 0.357 | 0.2757 | Yes |
| 43 | Rrp9 | 4301 | 0.356 | 0.2810 | Yes |
| 44 | Gsr | 4324 | 0.354 | 0.2870 | Yes |
| 45 | Pik3r3 | 4383 | 0.350 | 0.2916 | Yes |
| 46 | Rpn1 | 4570 | 0.342 | 0.2914 | Yes |
| 47 | Idi1 | 4750 | 0.336 | 0.2913 | Yes |
| 48 | Nup205 | 4763 | 0.335 | 0.2973 | Yes |
| 49 | Stard4 | 4900 | 0.328 | 0.2986 | Yes |
| 50 | Ppia | 5095 | 0.323 | 0.2977 | Yes |
| 51 | Ddx39a | 5168 | 0.321 | 0.3013 | Yes |
| 52 | Pdk1 | 5358 | 0.316 | 0.3004 | Yes |
| 53 | Ufm1 | 5419 | 0.311 | 0.3042 | Yes |
| 54 | Actr3 | 5724 | 0.295 | 0.2988 | Yes |
| 55 | Asns | 5817 | 0.290 | 0.3010 | Yes |
| 56 | Aurka | 5957 | 0.284 | 0.3014 | Yes |
| 57 | Rpa1 | 6088 | 0.278 | 0.3020 | Yes |
| 58 | Dhcr24 | 6207 | 0.276 | 0.3030 | Yes |
| 59 | Ifrd1 | 6228 | 0.275 | 0.3075 | Yes |
| 60 | Gmps | 6270 | 0.274 | 0.3113 | Yes |
| 61 | Rab1a | 6299 | 0.272 | 0.3155 | Yes |
| 62 | Pgk1 | 6358 | 0.270 | 0.3185 | Yes |
| 63 | P4ha1 | 6371 | 0.270 | 0.3233 | Yes |
| 64 | Acaca | 6427 | 0.267 | 0.3264 | Yes |
| 65 | Cyb5b | 6544 | 0.261 | 0.3272 | Yes |
| 66 | Serp1 | 6562 | 0.259 | 0.3315 | Yes |
| 67 | Ssr1 | 6748 | 0.250 | 0.3296 | Yes |
| 68 | Gtf2h1 | 6836 | 0.247 | 0.3312 | Yes |
| 69 | Nampt | 6890 | 0.244 | 0.3339 | Yes |
| 70 | Wars1 | 7004 | 0.239 | 0.3344 | Yes |
| 71 | Nfyc | 7048 | 0.237 | 0.3374 | Yes |
| 72 | Immt | 7162 | 0.234 | 0.3377 | Yes |
| 73 | Psmc4 | 7371 | 0.228 | 0.3345 | No |
| 74 | Ykt6 | 7408 | 0.226 | 0.3375 | No |
| 75 | Psmd14 | 7915 | 0.209 | 0.3231 | No |
| 76 | Igfbp5 | 7932 | 0.209 | 0.3265 | No |
| 77 | Hmgcs1 | 8072 | 0.206 | 0.3254 | No |
| 78 | Pfkl | 8226 | 0.199 | 0.3236 | No |
| 79 | Gclc | 8470 | 0.190 | 0.3184 | No |
| 80 | Psmc6 | 8605 | 0.185 | 0.3171 | No |
| 81 | Sc5d | 8689 | 0.181 | 0.3175 | No |
| 82 | Cth | 8705 | 0.180 | 0.3204 | No |
| 83 | Pnp | 8808 | 0.176 | 0.3201 | No |
| 84 | Psme3 | 8976 | 0.170 | 0.3173 | No |
| 85 | M6pr | 9047 | 0.167 | 0.3179 | No |
| 86 | Shmt2 | 9077 | 0.165 | 0.3200 | No |
| 87 | Vldlr | 9301 | 0.163 | 0.3150 | No |
| 88 | Pitpnb | 9304 | 0.163 | 0.3181 | No |
| 89 | Trib3 | 9511 | 0.154 | 0.3135 | No |
| 90 | Mthfd2 | 9640 | 0.150 | 0.3117 | No |
| 91 | Gpi1 | 9678 | 0.149 | 0.3132 | No |
| 92 | Tpi1 | 9824 | 0.142 | 0.3107 | No |
| 93 | Xbp1 | 9862 | 0.141 | 0.3120 | No |
| 94 | Pno1 | 10232 | 0.134 | 0.3011 | No |
| 95 | Dhcr7 | 10239 | 0.134 | 0.3035 | No |
| 96 | Txnrd1 | 10397 | 0.128 | 0.3002 | No |
| 97 | Ube2d3 | 10706 | 0.117 | 0.2912 | No |
| 98 | Sec11a | 10709 | 0.117 | 0.2934 | No |
| 99 | Ldlr | 10740 | 0.116 | 0.2945 | No |
| 100 | Map2k3 | 11029 | 0.105 | 0.2860 | No |
| 101 | Tm7sf2 | 11217 | 0.098 | 0.2811 | No |
| 102 | Cfp | 11363 | 0.093 | 0.2776 | No |
| 103 | Psmc2 | 11436 | 0.091 | 0.2767 | No |
| 104 | Elovl6 | 11788 | 0.078 | 0.2654 | No |
| 105 | Nmt1 | 11911 | 0.073 | 0.2623 | No |
| 106 | Lta4h | 12083 | 0.066 | 0.2574 | No |
| 107 | Aldoa | 12166 | 0.063 | 0.2556 | No |
| 108 | Psat1 | 12410 | 0.054 | 0.2477 | No |
| 109 | Psmd12 | 12618 | 0.046 | 0.2411 | No |
| 110 | Hk2 | 12685 | 0.043 | 0.2395 | No |
| 111 | Gsk3b | 12744 | 0.041 | 0.2382 | No |
| 112 | Nfil3 | 12866 | 0.037 | 0.2345 | No |
| 113 | Slc7a5 | 13113 | 0.028 | 0.2260 | No |
| 114 | G6pdx | 13142 | 0.027 | 0.2255 | No |
| 115 | Eef1e1 | 13204 | 0.026 | 0.2238 | No |
| 116 | Fads2 | 13526 | 0.016 | 0.2124 | No |
| 117 | Dhfr | 13559 | 0.014 | 0.2115 | No |
| 118 | Tcea1 | 13573 | 0.014 | 0.2113 | No |
| 119 | Uchl5 | 13805 | 0.007 | 0.2030 | No |
| 120 | Gla | 13998 | 0.002 | 0.1960 | No |
| 121 | Tbk1 | 14887 | -0.018 | 0.1640 | No |
| 122 | Atp6v1d | 15039 | -0.024 | 0.1589 | No |
| 123 | Pdap1 | 15048 | -0.024 | 0.1591 | No |
| 124 | Slc2a3 | 15050 | -0.024 | 0.1595 | No |
| 125 | Fgl2 | 15070 | -0.025 | 0.1593 | No |
| 126 | Phgdh | 15073 | -0.025 | 0.1597 | No |
| 127 | Tuba4a | 15279 | -0.032 | 0.1528 | No |
| 128 | Rdh11 | 15398 | -0.036 | 0.1492 | No |
| 129 | Hspe1 | 15590 | -0.043 | 0.1431 | No |
| 130 | Fads1 | 15594 | -0.043 | 0.1438 | No |
| 131 | Slc1a5 | 15801 | -0.051 | 0.1372 | No |
| 132 | Cops5 | 15950 | -0.056 | 0.1329 | No |
| 133 | Elovl5 | 15987 | -0.058 | 0.1327 | No |
| 134 | Sqstm1 | 16280 | -0.067 | 0.1233 | No |
| 135 | Psmd13 | 16349 | -0.069 | 0.1222 | No |
| 136 | Cdkn1a | 16430 | -0.073 | 0.1207 | No |
| 137 | Slc6a6 | 16481 | -0.075 | 0.1203 | No |
| 138 | Ccng1 | 16538 | -0.076 | 0.1197 | No |
| 139 | Slc1a4 | 16653 | -0.080 | 0.1171 | No |
| 140 | Nfkbib | 16782 | -0.085 | 0.1140 | No |
| 141 | Adipor2 | 16802 | -0.086 | 0.1150 | No |
| 142 | Bhlhe40 | 16805 | -0.086 | 0.1166 | No |
| 143 | Ddit4 | 16943 | -0.090 | 0.1133 | No |
| 144 | Sord | 17053 | -0.094 | 0.1111 | No |
| 145 | Psma3 | 17056 | -0.094 | 0.1129 | No |
| 146 | Cacybp | 17095 | -0.096 | 0.1133 | No |
| 147 | Slc37a4 | 17136 | -0.098 | 0.1138 | No |
| 148 | Tubg1 | 17206 | -0.100 | 0.1132 | No |
| 149 | Polr3g | 17424 | -0.108 | 0.1073 | No |
| 150 | Tmem97 | 17425 | -0.108 | 0.1094 | No |
| 151 | Ifi30 | 17666 | -0.116 | 0.1029 | No |
| 152 | Mthfd2l | 17695 | -0.117 | 0.1041 | No |
| 153 | Ppp1r15a | 17705 | -0.117 | 0.1060 | No |
| 154 | Psmb5 | 18048 | -0.130 | 0.0960 | No |
| 155 | Rit1 | 18273 | -0.138 | 0.0905 | No |
| 156 | Prdx1 | 18334 | -0.141 | 0.0910 | No |
| 157 | Ung | 18456 | -0.145 | 0.0894 | No |
| 158 | Eif2s2 | 18649 | -0.152 | 0.0853 | No |
| 159 | Ddit3 | 18774 | -0.158 | 0.0838 | No |
| 160 | Arpc5l | 19143 | -0.169 | 0.0736 | No |
| 161 | Srd5a1 | 19710 | -0.189 | 0.0566 | No |
| 162 | Tomm40 | 19739 | -0.191 | 0.0593 | No |
| 163 | Fkbp2 | 20016 | -0.200 | 0.0530 | No |
| 164 | Psph | 20128 | -0.205 | 0.0529 | No |
| 165 | Egln3 | 20186 | -0.207 | 0.0548 | No |
| 166 | Add3 | 20261 | -0.210 | 0.0561 | No |
| 167 | Sdf2l1 | 20770 | -0.223 | 0.0419 | No |
| 168 | Ebp | 20773 | -0.223 | 0.0461 | No |
| 169 | Nupr1 | 20811 | -0.225 | 0.0491 | No |
| 170 | Gbe1 | 20883 | -0.227 | 0.0508 | No |
| 171 | Psma4 | 21377 | -0.250 | 0.0376 | No |
| 172 | Ppa1 | 21681 | -0.260 | 0.0316 | No |
| 173 | Fdxr | 21779 | -0.264 | 0.0331 | No |
| 174 | Skap2 | 22254 | -0.285 | 0.0213 | No |
| 175 | Psmg1 | 22461 | -0.293 | 0.0194 | No |
| 176 | Ctsc | 22532 | -0.296 | 0.0225 | No |
| 177 | Btg2 | 23080 | -0.321 | 0.0087 | No |
| 178 | Plod2 | 23100 | -0.322 | 0.0142 | No |
| 179 | Pgm1 | 23222 | -0.327 | 0.0161 | No |
| 180 | Eno1b | 23452 | -0.340 | 0.0142 | No |
| 181 | Idh1 | 23503 | -0.342 | 0.0190 | No |
| 182 | Mllt11 | 23683 | -0.353 | 0.0192 | No |
| 183 | Qdpr | 23718 | -0.355 | 0.0248 | No |
| 184 | Sla | 24043 | -0.374 | 0.0202 | No |
| 185 | Ldha | 24334 | -0.392 | 0.0171 | No |
| 186 | Cxcr4 | 24615 | -0.409 | 0.0147 | No |
| 187 | Tes | 25259 | -0.453 | -0.0000 | No |
| 188 | Slc2a1 | 25874 | -0.513 | -0.0126 | No |
| 189 | Glrx | 26136 | -0.541 | -0.0117 | No |
| 190 | Itgb2 | 26614 | -0.608 | -0.0174 | No |
| 191 | Niban1 | 26725 | -0.625 | -0.0095 | No |
| 192 | Coro1a | 26929 | -0.664 | -0.0041 | No |
| 193 | Cd9 | 27120 | -0.714 | 0.0027 | No |
| 194 | Dapp1 | 27298 | -0.776 | 0.0111 | No |

