Details for gene set HALLMARK_IL6_JAK_STAT3

Table: GSEA Results Summary

Dataset	MEP.MEP.ery_Pheno.cls #Group2_versus_Group4.MEP.ery_Pheno.cls #Group2_versus_Group4_repos
Phenotype	MEP.ery_Pheno.cls#Group2_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_IL6_JAK_STAT3_SIGNALING
Enrichment Score (ES)	-0.43517345
Normalized Enrichment Score (NES)	-1.3995571
Nominal p-value	0.12407407
FDR q-value	1.0
FWER p-Value	0.703

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Myd88	1290	0.579	-0.0229	No
2	Inhbe	1869	0.511	-0.0227	No
3	Dntt	2239	0.485	-0.0161	No
4	Ccr1	3107	0.420	-0.0302	No
5	Acvrl1	3620	0.389	-0.0327	No
6	Il12rb1	4081	0.367	-0.0342	No
7	Il1b	4091	0.367	-0.0193	No
8	Ptpn11	4735	0.336	-0.0287	No
9	Jun	5456	0.308	-0.0421	No
10	Il1r2	5547	0.303	-0.0328	No
11	Csf3r	6098	0.278	-0.0413	No
12	Cd36	6276	0.273	-0.0364	No
13	Socs3	6695	0.253	-0.0411	No
14	Hax1	8082	0.205	-0.0830	No
15	Stat1	8772	0.178	-0.1006	No
16	Il1r1	8897	0.173	-0.0980	No
17	Cd44	9068	0.166	-0.0973	No
18	Cntfr	9089	0.165	-0.0912	No
19	Map3k8	11970	0.071	-0.1929	No
20	Il4ra	13164	0.027	-0.2351	No
21	Il17rb	13180	0.026	-0.2346	No
22	Cd14	13321	0.021	-0.2388	No
23	Irf9	13479	0.017	-0.2438	No
24	Stat2	13759	0.008	-0.2536	No
25	Osmr	13865	0.004	-0.2572	No
26	Itgb3	14597	-0.007	-0.2834	No
27	Stam2	14777	-0.014	-0.2894	No
28	Pik3r5	14823	-0.016	-0.2904	No
29	Ptpn1	14893	-0.018	-0.2921	No
30	Ptpn2	15247	-0.030	-0.3037	No
31	Il6st	15266	-0.031	-0.3030	No
32	Il13ra1	15888	-0.054	-0.3234	No
33	A2m	16513	-0.076	-0.3429	No
34	Hmox1	17665	-0.116	-0.3799	No
35	Tnfrsf21	17813	-0.121	-0.3802	No
36	Irf1	17838	-0.122	-0.3760	No
37	Ifnar1	18079	-0.131	-0.3794	No
38	Cbl	18382	-0.143	-0.3844	No
39	Pim1	18431	-0.144	-0.3802	No
40	Itga4	18678	-0.153	-0.3828	No
41	Cd38	19498	-0.182	-0.4050	No
42	Grb2	19796	-0.192	-0.4078	No
43	Tnf	19855	-0.194	-0.4019	No
44	Tyk2	19952	-0.198	-0.3972	No
45	Il15ra	20839	-0.226	-0.4201	No
46	Tnfrsf12a	21244	-0.243	-0.4247	Yes
47	Bak1	21534	-0.256	-0.4246	Yes
48	Il9r	21600	-0.259	-0.4162	Yes
49	Acvr1b	21797	-0.265	-0.4123	Yes
50	Ebi3	21800	-0.265	-0.4014	Yes
51	Il7	21949	-0.271	-0.3956	Yes
52	Pdgfc	21984	-0.273	-0.3855	Yes
53	Cxcl10	22185	-0.282	-0.3811	Yes
54	Ifngr2	23280	-0.331	-0.4071	Yes
55	Tlr2	23476	-0.341	-0.4001	Yes
56	Socs1	23497	-0.342	-0.3866	Yes
57	Lepr	23961	-0.369	-0.3882	Yes
58	Fas	24240	-0.386	-0.3823	Yes
59	Tnfrsf1b	24361	-0.393	-0.3704	Yes
60	Il18r1	24955	-0.430	-0.3742	Yes
61	Ifngr1	25570	-0.482	-0.3765	Yes
62	Stat3	25892	-0.515	-0.3669	Yes
63	Ltbr	25963	-0.522	-0.3478	Yes
64	Il2ra	26099	-0.536	-0.3305	Yes
65	Il10rb	26334	-0.567	-0.3156	Yes
66	Pf4	26336	-0.567	-0.2921	Yes
67	Il17ra	26545	-0.597	-0.2750	Yes
68	Il6	26567	-0.602	-0.2508	Yes
69	Il3ra	26813	-0.640	-0.2332	Yes
70	Crlf2	26820	-0.641	-0.2069	Yes
71	Tgfb1	26829	-0.642	-0.1806	Yes
72	Cd9	27120	-0.714	-0.1616	Yes
73	Il2rg	27203	-0.742	-0.1338	Yes
74	Csf1	27254	-0.759	-0.1042	Yes
75	Ltb	27379	-0.817	-0.0749	Yes
76	Tnfrsf1a	27499	-0.899	-0.0420	Yes
77	Csf2ra	27582	-1.104	0.0007	Yes