| Dataset | MEP.MEP.ery_Pheno.cls #Group2_versus_Group4.MEP.ery_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | MEP.ery_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.4841468 |
| Normalized Enrichment Score (NES) | 1.5688663 |
| Nominal p-value | 0.049335863 |
| FDR q-value | 0.5547571 |
| FWER p-Value | 0.37 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Nek2 | 168 | 0.948 | 0.0114 | Yes |
| 2 | Srsf1 | 238 | 0.870 | 0.0250 | Yes |
| 3 | Hspa8 | 374 | 0.796 | 0.0348 | Yes |
| 4 | Meis2 | 458 | 0.755 | 0.0457 | Yes |
| 5 | Amd1 | 705 | 0.691 | 0.0495 | Yes |
| 6 | Mcm2 | 842 | 0.654 | 0.0566 | Yes |
| 7 | Sqle | 886 | 0.644 | 0.0669 | Yes |
| 8 | Xpo1 | 954 | 0.636 | 0.0762 | Yes |
| 9 | Kpnb1 | 1004 | 0.628 | 0.0860 | Yes |
| 10 | Bard1 | 1024 | 0.623 | 0.0969 | Yes |
| 11 | Hnrnpu | 1028 | 0.622 | 0.1083 | Yes |
| 12 | Ccnd1 | 1054 | 0.616 | 0.1187 | Yes |
| 13 | Lmnb1 | 1113 | 0.605 | 0.1278 | Yes |
| 14 | Dr1 | 1394 | 0.566 | 0.1280 | Yes |
| 15 | Chaf1a | 1484 | 0.557 | 0.1351 | Yes |
| 16 | Mcm5 | 1485 | 0.557 | 0.1454 | Yes |
| 17 | Upf1 | 1488 | 0.557 | 0.1556 | Yes |
| 18 | Espl1 | 1497 | 0.556 | 0.1656 | Yes |
| 19 | Cdc6 | 1520 | 0.552 | 0.1750 | Yes |
| 20 | Hnrnpd | 1722 | 0.527 | 0.1774 | Yes |
| 21 | Ccna2 | 1775 | 0.519 | 0.1851 | Yes |
| 22 | Racgap1 | 1780 | 0.519 | 0.1945 | Yes |
| 23 | Nsd2 | 1909 | 0.508 | 0.1992 | Yes |
| 24 | Odc1 | 1939 | 0.506 | 0.2075 | Yes |
| 25 | Ccnf | 2151 | 0.492 | 0.2089 | Yes |
| 26 | Rad21 | 2228 | 0.486 | 0.2151 | Yes |
| 27 | Cdkn2c | 2266 | 0.481 | 0.2227 | Yes |
| 28 | Incenp | 2448 | 0.463 | 0.2246 | Yes |
| 29 | Bub1 | 2476 | 0.461 | 0.2322 | Yes |
| 30 | Smc1a | 2491 | 0.459 | 0.2401 | Yes |
| 31 | Cdk1 | 2504 | 0.458 | 0.2481 | Yes |
| 32 | Lbr | 2523 | 0.456 | 0.2559 | Yes |
| 33 | Prc1 | 2555 | 0.453 | 0.2632 | Yes |
| 34 | Kif2c | 2620 | 0.448 | 0.2691 | Yes |
| 35 | Mcm3 | 2682 | 0.446 | 0.2751 | Yes |
| 36 | Cenpf | 2749 | 0.443 | 0.2809 | Yes |
| 37 | Polq | 2883 | 0.436 | 0.2841 | Yes |
| 38 | Tfdp1 | 2904 | 0.434 | 0.2914 | Yes |
| 39 | Kif11 | 2942 | 0.431 | 0.2980 | Yes |
| 40 | Tent4a | 3058 | 0.424 | 0.3016 | Yes |
| 41 | Sfpq | 3067 | 0.423 | 0.3092 | Yes |
| 42 | Top2a | 3073 | 0.422 | 0.3168 | Yes |
| 43 | Mybl2 | 3372 | 0.403 | 0.3134 | Yes |
| 44 | Cdc25a | 3421 | 0.399 | 0.3190 | Yes |
| 45 | Pole | 3542 | 0.395 | 0.3219 | Yes |
| 46 | Cul1 | 3556 | 0.394 | 0.3287 | Yes |
| 47 | Plk1 | 3649 | 0.388 | 0.3325 | Yes |
| 48 | Mcm6 | 3663 | 0.387 | 0.3392 | Yes |
| 49 | Kif4 | 3741 | 0.384 | 0.3435 | Yes |
| 50 | Prim2 | 3780 | 0.382 | 0.3492 | Yes |
| 51 | Uck2 | 4028 | 0.370 | 0.3470 | Yes |
| 52 | Mki67 | 4033 | 0.370 | 0.3537 | Yes |
| 53 | Tra2b | 4117 | 0.366 | 0.3574 | Yes |
| 54 | Cks2 | 4122 | 0.365 | 0.3640 | Yes |
| 55 | Cenpe | 4126 | 0.365 | 0.3707 | Yes |
| 56 | Tacc3 | 4143 | 0.365 | 0.3768 | Yes |
| 57 | Plk4 | 4162 | 0.362 | 0.3829 | Yes |
| 58 | Syncrip | 4163 | 0.362 | 0.3896 | Yes |
| 59 | Chek1 | 4188 | 0.361 | 0.3954 | Yes |
| 60 | Odf2 | 4261 | 0.357 | 0.3993 | Yes |
| 61 | Hmmr | 4274 | 0.356 | 0.4055 | Yes |
| 62 | Nasp | 4336 | 0.353 | 0.4098 | Yes |
| 63 | Tpx2 | 4360 | 0.352 | 0.4154 | Yes |
| 64 | Kif15 | 4579 | 0.342 | 0.4138 | Yes |
| 65 | H2az1 | 4709 | 0.337 | 0.4153 | Yes |
| 66 | Kif23 | 4772 | 0.335 | 0.4192 | Yes |
| 67 | Ddx39a | 5168 | 0.321 | 0.4108 | Yes |
| 68 | G3bp1 | 5174 | 0.320 | 0.4165 | Yes |
| 69 | Tmpo | 5206 | 0.318 | 0.4212 | Yes |
| 70 | Srsf10 | 5381 | 0.314 | 0.4207 | Yes |
| 71 | Suv39h1 | 5509 | 0.306 | 0.4217 | Yes |
| 72 | Rad54l | 5525 | 0.305 | 0.4268 | Yes |
| 73 | Rbl1 | 5561 | 0.302 | 0.4311 | Yes |
| 74 | Exo1 | 5660 | 0.298 | 0.4330 | Yes |
| 75 | Hira | 5740 | 0.294 | 0.4356 | Yes |
| 76 | Cul3 | 5929 | 0.285 | 0.4340 | Yes |
| 77 | Aurka | 5957 | 0.284 | 0.4383 | Yes |
| 78 | Prmt5 | 6018 | 0.281 | 0.4413 | Yes |
| 79 | Orc5 | 6082 | 0.278 | 0.4441 | Yes |
| 80 | Ttk | 6389 | 0.269 | 0.4379 | Yes |
| 81 | Ncl | 6459 | 0.266 | 0.4403 | Yes |
| 82 | Numa1 | 6503 | 0.263 | 0.4436 | Yes |
| 83 | Cdc7 | 6585 | 0.259 | 0.4454 | Yes |
| 84 | H2bc12 | 6672 | 0.254 | 0.4470 | Yes |
| 85 | Fancc | 6713 | 0.252 | 0.4502 | Yes |
| 86 | Ccnt1 | 6803 | 0.248 | 0.4515 | Yes |
| 87 | Aurkb | 6877 | 0.245 | 0.4534 | Yes |
| 88 | Cul4a | 7025 | 0.238 | 0.4524 | Yes |
| 89 | Fbxo5 | 7370 | 0.228 | 0.4441 | Yes |
| 90 | Kif22 | 7589 | 0.222 | 0.4402 | Yes |
| 91 | Tnpo2 | 7722 | 0.217 | 0.4394 | Yes |
| 92 | E2f3 | 7725 | 0.217 | 0.4433 | Yes |
| 93 | Dbf4 | 7731 | 0.217 | 0.4472 | Yes |
| 94 | Hus1 | 7742 | 0.216 | 0.4508 | Yes |
| 95 | Rad23b | 7751 | 0.216 | 0.4545 | Yes |
| 96 | E2f1 | 7787 | 0.214 | 0.4572 | Yes |
| 97 | Prpf4b | 7875 | 0.211 | 0.4579 | Yes |
| 98 | Wrn | 8096 | 0.205 | 0.4536 | Yes |
| 99 | Nup98 | 8118 | 0.204 | 0.4566 | Yes |
| 100 | Nolc1 | 8135 | 0.203 | 0.4598 | Yes |
| 101 | E2f2 | 8142 | 0.203 | 0.4633 | Yes |
| 102 | Nup50 | 8220 | 0.200 | 0.4642 | Yes |
| 103 | Cul5 | 8243 | 0.199 | 0.4671 | Yes |
| 104 | Brca2 | 8336 | 0.195 | 0.4673 | Yes |
| 105 | Mapk14 | 8396 | 0.193 | 0.4687 | Yes |
| 106 | Smarcc1 | 8426 | 0.191 | 0.4712 | Yes |
| 107 | Slc7a1 | 8502 | 0.189 | 0.4720 | Yes |
| 108 | Ube2s | 8510 | 0.189 | 0.4752 | Yes |
| 109 | Pml | 8519 | 0.188 | 0.4784 | Yes |
| 110 | Cdc27 | 8659 | 0.182 | 0.4767 | Yes |
| 111 | Ilf3 | 8664 | 0.182 | 0.4799 | Yes |
| 112 | Cdc25b | 8728 | 0.179 | 0.4809 | Yes |
| 113 | Pafah1b1 | 8731 | 0.179 | 0.4841 | Yes |
| 114 | Traip | 8936 | 0.172 | 0.4799 | No |
| 115 | Hmgb3 | 9042 | 0.167 | 0.4791 | No |
| 116 | Orc6 | 9307 | 0.163 | 0.4725 | No |
| 117 | Cdc45 | 9320 | 0.162 | 0.4751 | No |
| 118 | Mad2l1 | 9374 | 0.160 | 0.4761 | No |
| 119 | Sap30 | 9419 | 0.158 | 0.4774 | No |
| 120 | Casp8ap2 | 9551 | 0.153 | 0.4755 | No |
| 121 | Smc4 | 9650 | 0.149 | 0.4746 | No |
| 122 | Knl1 | 9712 | 0.147 | 0.4751 | No |
| 123 | Kif20b | 9728 | 0.147 | 0.4773 | No |
| 124 | Egf | 9774 | 0.145 | 0.4783 | No |
| 125 | Slc38a1 | 9844 | 0.141 | 0.4784 | No |
| 126 | Smc2 | 10114 | 0.139 | 0.4712 | No |
| 127 | Ctcf | 10377 | 0.129 | 0.4640 | No |
| 128 | Map3k20 | 10486 | 0.125 | 0.4624 | No |
| 129 | Ccnb2 | 10527 | 0.124 | 0.4632 | No |
| 130 | Pola2 | 10567 | 0.122 | 0.4640 | No |
| 131 | Jpt1 | 10575 | 0.121 | 0.4660 | No |
| 132 | Ewsr1 | 10785 | 0.114 | 0.4605 | No |
| 133 | Lig3 | 10801 | 0.113 | 0.4620 | No |
| 134 | Stil | 10820 | 0.113 | 0.4635 | No |
| 135 | Gspt1 | 10830 | 0.112 | 0.4652 | No |
| 136 | Abl1 | 11038 | 0.104 | 0.4596 | No |
| 137 | Pds5b | 11116 | 0.102 | 0.4587 | No |
| 138 | Ezh2 | 11297 | 0.095 | 0.4538 | No |
| 139 | Stmn1 | 11310 | 0.095 | 0.4552 | No |
| 140 | Rasal2 | 11455 | 0.090 | 0.4516 | No |
| 141 | Mtf2 | 11467 | 0.090 | 0.4528 | No |
| 142 | Birc5 | 11473 | 0.090 | 0.4543 | No |
| 143 | Pbk | 11492 | 0.089 | 0.4553 | No |
| 144 | E2f4 | 11666 | 0.083 | 0.4505 | No |
| 145 | Cbx1 | 11790 | 0.078 | 0.4474 | No |
| 146 | Ndc80 | 11993 | 0.070 | 0.4414 | No |
| 147 | Stag1 | 12066 | 0.067 | 0.4400 | No |
| 148 | Ss18 | 12236 | 0.060 | 0.4349 | No |
| 149 | Ythdc1 | 12250 | 0.060 | 0.4356 | No |
| 150 | Kif5b | 12568 | 0.048 | 0.4249 | No |
| 151 | Notch2 | 12732 | 0.042 | 0.4197 | No |
| 152 | Katna1 | 12817 | 0.038 | 0.4174 | No |
| 153 | Slc12a2 | 12854 | 0.037 | 0.4167 | No |
| 154 | Atrx | 13089 | 0.029 | 0.4087 | No |
| 155 | Slc7a5 | 13113 | 0.028 | 0.4084 | No |
| 156 | Top1 | 13242 | 0.024 | 0.4042 | No |
| 157 | Snrpd1 | 13362 | 0.020 | 0.4002 | No |
| 158 | Cenpa | 13511 | 0.016 | 0.3951 | No |
| 159 | Chmp1a | 13689 | 0.011 | 0.3889 | No |
| 160 | Efna5 | 13815 | 0.006 | 0.3844 | No |
| 161 | Rpa2 | 13925 | 0.003 | 0.3805 | No |
| 162 | Dtymk | 14008 | 0.002 | 0.3776 | No |
| 163 | Nusap1 | 14565 | -0.006 | 0.3574 | No |
| 164 | Gins2 | 14669 | -0.010 | 0.3538 | No |
| 165 | Dkc1 | 14749 | -0.013 | 0.3512 | No |
| 166 | Srsf2 | 14795 | -0.015 | 0.3498 | No |
| 167 | Cks1b | 15341 | -0.034 | 0.3305 | No |
| 168 | Arid4a | 15539 | -0.042 | 0.3241 | No |
| 169 | Cdkn1b | 15940 | -0.055 | 0.3106 | No |
| 170 | Troap | 16359 | -0.070 | 0.2966 | No |
| 171 | Hif1a | 16660 | -0.081 | 0.2871 | No |
| 172 | Bub3 | 16858 | -0.088 | 0.2816 | No |
| 173 | Smad3 | 17180 | -0.099 | 0.2717 | No |
| 174 | Mnat1 | 17192 | -0.100 | 0.2731 | No |
| 175 | Cdc20 | 17402 | -0.107 | 0.2675 | No |
| 176 | Ube2c | 17631 | -0.115 | 0.2613 | No |
| 177 | Pttg1 | 17886 | -0.124 | 0.2543 | No |
| 178 | Kmt5a | 18166 | -0.134 | 0.2466 | No |
| 179 | Cdk4 | 19230 | -0.172 | 0.2110 | No |
| 180 | Bcl3 | 19273 | -0.174 | 0.2127 | No |
| 181 | Cdkn3 | 19384 | -0.178 | 0.2120 | No |
| 182 | Tle3 | 19993 | -0.199 | 0.1935 | No |
| 183 | Dmd | 20101 | -0.204 | 0.1933 | No |
| 184 | H2ax | 20878 | -0.227 | 0.1692 | No |
| 185 | H2az2 | 21169 | -0.240 | 0.1631 | No |
| 186 | Rps6ka5 | 21989 | -0.273 | 0.1382 | No |
| 187 | Hmga1b | 23410 | -0.338 | 0.0927 | No |
| 188 | Foxn3 | 23443 | -0.339 | 0.0978 | No |
| 189 | Myc | 23468 | -0.341 | 0.1032 | No |
| 190 | Marcks | 24360 | -0.393 | 0.0779 | No |
| 191 | Pura | 24582 | -0.407 | 0.0774 | No |
| 192 | Atf5 | 24989 | -0.432 | 0.0706 | No |
| 193 | Tgfb1 | 26829 | -0.642 | 0.0153 | No |
| 194 | Meis1 | 27051 | -0.695 | 0.0201 | No |

