| Dataset | MEP.MEP.ery_Pheno.cls #Group2_versus_Group4.MEP.ery_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | MEP.ery_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.49107167 |
| Normalized Enrichment Score (NES) | 1.4685903 |
| Nominal p-value | 0.13549618 |
| FDR q-value | 0.584537 |
| FWER p-Value | 0.587 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Dck | 195 | 0.924 | 0.0101 | Yes |
| 2 | Srsf1 | 238 | 0.870 | 0.0248 | Yes |
| 3 | Ipo7 | 520 | 0.736 | 0.0283 | Yes |
| 4 | Rad51c | 715 | 0.688 | 0.0341 | Yes |
| 5 | Mcm2 | 842 | 0.654 | 0.0417 | Yes |
| 6 | Xpo1 | 954 | 0.636 | 0.0495 | Yes |
| 7 | Bard1 | 1024 | 0.623 | 0.0586 | Yes |
| 8 | Melk | 1084 | 0.610 | 0.0679 | Yes |
| 9 | Lmnb1 | 1113 | 0.605 | 0.0781 | Yes |
| 10 | Ccp110 | 1131 | 0.602 | 0.0888 | Yes |
| 11 | Ccne1 | 1393 | 0.566 | 0.0898 | Yes |
| 12 | Ncapd2 | 1410 | 0.565 | 0.0997 | Yes |
| 13 | Mcm5 | 1485 | 0.557 | 0.1074 | Yes |
| 14 | Espl1 | 1497 | 0.556 | 0.1174 | Yes |
| 15 | Hnrnpd | 1722 | 0.527 | 0.1191 | Yes |
| 16 | Dlgap5 | 1725 | 0.527 | 0.1288 | Yes |
| 17 | Racgap1 | 1780 | 0.519 | 0.1365 | Yes |
| 18 | Nup107 | 1893 | 0.510 | 0.1420 | Yes |
| 19 | Dnmt1 | 1901 | 0.509 | 0.1512 | Yes |
| 20 | Ssrp1 | 1937 | 0.506 | 0.1594 | Yes |
| 21 | Rbbp7 | 2015 | 0.500 | 0.1659 | Yes |
| 22 | Tfrc | 2104 | 0.495 | 0.1719 | Yes |
| 23 | Rad21 | 2228 | 0.486 | 0.1765 | Yes |
| 24 | Cdkn2c | 2266 | 0.481 | 0.1841 | Yes |
| 25 | Timeless | 2270 | 0.480 | 0.1930 | Yes |
| 26 | Hells | 2310 | 0.477 | 0.2005 | Yes |
| 27 | Mcm4 | 2311 | 0.477 | 0.2094 | Yes |
| 28 | Slbp | 2315 | 0.476 | 0.2181 | Yes |
| 29 | Nap1l1 | 2455 | 0.462 | 0.2217 | Yes |
| 30 | Smc1a | 2491 | 0.459 | 0.2290 | Yes |
| 31 | Cdk1 | 2504 | 0.458 | 0.2371 | Yes |
| 32 | Lbr | 2523 | 0.456 | 0.2449 | Yes |
| 33 | Smc3 | 2597 | 0.450 | 0.2507 | Yes |
| 34 | Kif2c | 2620 | 0.448 | 0.2582 | Yes |
| 35 | Mcm3 | 2682 | 0.446 | 0.2643 | Yes |
| 36 | Zw10 | 2708 | 0.445 | 0.2717 | Yes |
| 37 | Prps1 | 2769 | 0.442 | 0.2778 | Yes |
| 38 | Brca1 | 2927 | 0.433 | 0.2801 | Yes |
| 39 | Cse1l | 2952 | 0.430 | 0.2873 | Yes |
| 40 | Top2a | 3073 | 0.422 | 0.2908 | Yes |
| 41 | Mybl2 | 3372 | 0.403 | 0.2874 | Yes |
| 42 | Bub1b | 3380 | 0.402 | 0.2947 | Yes |
| 43 | Cdc25a | 3421 | 0.399 | 0.3007 | Yes |
| 44 | Pole | 3542 | 0.395 | 0.3037 | Yes |
| 45 | Plk1 | 3649 | 0.388 | 0.3070 | Yes |
| 46 | Mcm6 | 3663 | 0.387 | 0.3138 | Yes |
| 47 | Kif4 | 3741 | 0.384 | 0.3181 | Yes |
| 48 | Rrm2 | 3779 | 0.383 | 0.3239 | Yes |
| 49 | Prim2 | 3780 | 0.382 | 0.3311 | Yes |
| 50 | Spc25 | 3888 | 0.376 | 0.3342 | Yes |
| 51 | Mki67 | 4033 | 0.370 | 0.3358 | Yes |
| 52 | Tra2b | 4117 | 0.366 | 0.3396 | Yes |
| 53 | Wdr90 | 4120 | 0.366 | 0.3464 | Yes |
| 54 | Cks2 | 4122 | 0.365 | 0.3532 | Yes |
| 55 | Cenpe | 4126 | 0.365 | 0.3599 | Yes |
| 56 | Atad2 | 4133 | 0.365 | 0.3665 | Yes |
| 57 | Tacc3 | 4143 | 0.365 | 0.3729 | Yes |
| 58 | Plk4 | 4162 | 0.362 | 0.3790 | Yes |
| 59 | Syncrip | 4163 | 0.362 | 0.3858 | Yes |
| 60 | Chek1 | 4188 | 0.361 | 0.3917 | Yes |
| 61 | Hmmr | 4274 | 0.356 | 0.3952 | Yes |
| 62 | Nop56 | 4326 | 0.353 | 0.3999 | Yes |
| 63 | Nasp | 4336 | 0.353 | 0.4062 | Yes |
| 64 | Ubr7 | 4394 | 0.350 | 0.4106 | Yes |
| 65 | Ing3 | 4701 | 0.338 | 0.4058 | Yes |
| 66 | H2az1 | 4709 | 0.337 | 0.4118 | Yes |
| 67 | Nup205 | 4763 | 0.335 | 0.4162 | Yes |
| 68 | Depdc1a | 4997 | 0.325 | 0.4137 | Yes |
| 69 | Ddx39a | 5168 | 0.321 | 0.4135 | Yes |
| 70 | Tmpo | 5206 | 0.318 | 0.4181 | Yes |
| 71 | Eif2s1 | 5315 | 0.318 | 0.4201 | Yes |
| 72 | Xrcc6 | 5382 | 0.314 | 0.4235 | Yes |
| 73 | Wee1 | 5473 | 0.308 | 0.4260 | Yes |
| 74 | Spag5 | 5489 | 0.307 | 0.4312 | Yes |
| 75 | Cbx5 | 5496 | 0.307 | 0.4367 | Yes |
| 76 | Suv39h1 | 5509 | 0.306 | 0.4420 | Yes |
| 77 | Lig1 | 5635 | 0.299 | 0.4430 | Yes |
| 78 | Prkdc | 5761 | 0.293 | 0.4439 | Yes |
| 79 | Cdca8 | 5785 | 0.292 | 0.4485 | Yes |
| 80 | Nbn | 5887 | 0.287 | 0.4502 | Yes |
| 81 | Kif18b | 5930 | 0.285 | 0.4539 | Yes |
| 82 | Aurka | 5957 | 0.284 | 0.4583 | Yes |
| 83 | Rpa1 | 6088 | 0.278 | 0.4587 | Yes |
| 84 | Brms1l | 6097 | 0.278 | 0.4636 | Yes |
| 85 | Pnn | 6222 | 0.276 | 0.4643 | Yes |
| 86 | Cit | 6225 | 0.276 | 0.4693 | Yes |
| 87 | Donson | 6368 | 0.270 | 0.4692 | Yes |
| 88 | Pcna | 6382 | 0.269 | 0.4737 | Yes |
| 89 | Orc2 | 6430 | 0.267 | 0.4770 | Yes |
| 90 | Diaph3 | 6532 | 0.261 | 0.4782 | Yes |
| 91 | Psmc3ip | 6551 | 0.260 | 0.4824 | Yes |
| 92 | Mcm7 | 6679 | 0.254 | 0.4825 | Yes |
| 93 | Msh2 | 6838 | 0.247 | 0.4813 | Yes |
| 94 | Aurkb | 6877 | 0.245 | 0.4845 | Yes |
| 95 | Anp32e | 6899 | 0.244 | 0.4883 | Yes |
| 96 | Mms22l | 7153 | 0.234 | 0.4834 | Yes |
| 97 | Tipin | 7426 | 0.225 | 0.4777 | Yes |
| 98 | Mre11a | 7436 | 0.225 | 0.4816 | Yes |
| 99 | Trip13 | 7570 | 0.222 | 0.4809 | Yes |
| 100 | Kif22 | 7589 | 0.222 | 0.4844 | Yes |
| 101 | Hus1 | 7742 | 0.216 | 0.4828 | Yes |
| 102 | Ppp1r8 | 7801 | 0.214 | 0.4847 | Yes |
| 103 | Gins4 | 8032 | 0.207 | 0.4802 | Yes |
| 104 | Nolc1 | 8135 | 0.203 | 0.4803 | Yes |
| 105 | Brca2 | 8336 | 0.195 | 0.4766 | Yes |
| 106 | Ube2s | 8510 | 0.189 | 0.4738 | Yes |
| 107 | Dclre1b | 8588 | 0.186 | 0.4745 | Yes |
| 108 | Ilf3 | 8664 | 0.182 | 0.4751 | Yes |
| 109 | Cdc25b | 8728 | 0.179 | 0.4762 | Yes |
| 110 | Nup153 | 8823 | 0.176 | 0.4760 | Yes |
| 111 | Tbrg4 | 8826 | 0.176 | 0.4792 | Yes |
| 112 | Cdkn2a | 9004 | 0.169 | 0.4759 | Yes |
| 113 | Eed | 9035 | 0.167 | 0.4779 | Yes |
| 114 | Hmgb3 | 9042 | 0.167 | 0.4808 | Yes |
| 115 | Ak2 | 9290 | 0.163 | 0.4749 | Yes |
| 116 | Rad51ap1 | 9294 | 0.163 | 0.4778 | Yes |
| 117 | Orc6 | 9307 | 0.163 | 0.4804 | Yes |
| 118 | Mad2l1 | 9374 | 0.160 | 0.4810 | Yes |
| 119 | Tk1 | 9485 | 0.156 | 0.4799 | Yes |
| 120 | Phf5a | 9487 | 0.156 | 0.4827 | Yes |
| 121 | Gins3 | 9558 | 0.153 | 0.4830 | Yes |
| 122 | Rfc1 | 9571 | 0.153 | 0.4854 | Yes |
| 123 | Shmt1 | 9610 | 0.151 | 0.4869 | Yes |
| 124 | Mthfd2 | 9640 | 0.150 | 0.4886 | Yes |
| 125 | Smc4 | 9650 | 0.149 | 0.4911 | Yes |
| 126 | Tubb5 | 9827 | 0.142 | 0.4873 | No |
| 127 | Usp1 | 9868 | 0.141 | 0.4885 | No |
| 128 | Exosc8 | 10103 | 0.139 | 0.4825 | No |
| 129 | Ctcf | 10377 | 0.129 | 0.4750 | No |
| 130 | Ccnb2 | 10527 | 0.124 | 0.4718 | No |
| 131 | Pola2 | 10567 | 0.122 | 0.4727 | No |
| 132 | Jpt1 | 10575 | 0.121 | 0.4747 | No |
| 133 | Gspt1 | 10830 | 0.112 | 0.4675 | No |
| 134 | Rad1 | 10961 | 0.106 | 0.4648 | No |
| 135 | Pds5b | 11116 | 0.102 | 0.4610 | No |
| 136 | Ezh2 | 11297 | 0.095 | 0.4563 | No |
| 137 | Stmn1 | 11310 | 0.095 | 0.4576 | No |
| 138 | Pms2 | 11422 | 0.091 | 0.4552 | No |
| 139 | Chek2 | 11430 | 0.091 | 0.4567 | No |
| 140 | Birc5 | 11473 | 0.090 | 0.4568 | No |
| 141 | Psip1 | 11494 | 0.089 | 0.4578 | No |
| 142 | Smc6 | 11649 | 0.083 | 0.4537 | No |
| 143 | Pold1 | 11669 | 0.082 | 0.4545 | No |
| 144 | Dut | 11682 | 0.082 | 0.4556 | No |
| 145 | Rad50 | 11850 | 0.075 | 0.4509 | No |
| 146 | Paics | 12001 | 0.070 | 0.4468 | No |
| 147 | Lyar | 12027 | 0.069 | 0.4471 | No |
| 148 | Pop7 | 12037 | 0.068 | 0.4481 | No |
| 149 | Stag1 | 12066 | 0.067 | 0.4483 | No |
| 150 | Dek | 12154 | 0.064 | 0.4463 | No |
| 151 | Gins1 | 12178 | 0.063 | 0.4467 | No |
| 152 | Pan2 | 12481 | 0.051 | 0.4366 | No |
| 153 | Cenpm | 12509 | 0.050 | 0.4366 | No |
| 154 | Cnot9 | 12544 | 0.049 | 0.4362 | No |
| 155 | Ube2t | 12564 | 0.048 | 0.4364 | No |
| 156 | Dscc1 | 12822 | 0.038 | 0.4278 | No |
| 157 | Ranbp1 | 13066 | 0.030 | 0.4195 | No |
| 158 | Rfc3 | 13121 | 0.028 | 0.4180 | No |
| 159 | Pa2g4 | 13381 | 0.020 | 0.4089 | No |
| 160 | Lsm8 | 13571 | 0.014 | 0.4023 | No |
| 161 | Asf1b | 13602 | 0.013 | 0.4014 | No |
| 162 | Luc7l3 | 13828 | 0.006 | 0.3933 | No |
| 163 | Rpa2 | 13925 | 0.003 | 0.3899 | No |
| 164 | Pold3 | 14360 | -0.000 | 0.3740 | No |
| 165 | Ppm1d | 14707 | -0.012 | 0.3616 | No |
| 166 | Mlh1 | 14744 | -0.013 | 0.3606 | No |
| 167 | Srsf2 | 14795 | -0.015 | 0.3590 | No |
| 168 | Cks1b | 15341 | -0.034 | 0.3398 | No |
| 169 | Cdkn1b | 15940 | -0.055 | 0.3190 | No |
| 170 | Spc24 | 15986 | -0.058 | 0.3184 | No |
| 171 | Asf1a | 16185 | -0.064 | 0.3124 | No |
| 172 | Cdkn1a | 16430 | -0.073 | 0.3048 | No |
| 173 | Hmgb2 | 17091 | -0.096 | 0.2825 | No |
| 174 | Tubg1 | 17206 | -0.100 | 0.2802 | No |
| 175 | Cdc20 | 17402 | -0.107 | 0.2751 | No |
| 176 | Cdca3 | 17427 | -0.108 | 0.2763 | No |
| 177 | E2f8 | 17546 | -0.112 | 0.2741 | No |
| 178 | Pttg1 | 17886 | -0.124 | 0.2640 | No |
| 179 | Snrpb | 18280 | -0.139 | 0.2522 | No |
| 180 | Ung | 18456 | -0.145 | 0.2486 | No |
| 181 | Ran | 18740 | -0.156 | 0.2412 | No |
| 182 | Rfc2 | 18770 | -0.157 | 0.2430 | No |
| 183 | Cdk4 | 19230 | -0.172 | 0.2295 | No |
| 184 | Cdkn3 | 19384 | -0.178 | 0.2272 | No |
| 185 | Rnaseh2a | 19618 | -0.186 | 0.2222 | No |
| 186 | Nme1 | 19733 | -0.190 | 0.2216 | No |
| 187 | Trp53 | 20330 | -0.212 | 0.2038 | No |
| 188 | Nudt21 | 20865 | -0.226 | 0.1885 | No |
| 189 | H2ax | 20878 | -0.227 | 0.1923 | No |
| 190 | Rpa3 | 21036 | -0.234 | 0.1910 | No |
| 191 | Pole4 | 21213 | -0.242 | 0.1891 | No |
| 192 | Mxd3 | 21294 | -0.245 | 0.1907 | No |
| 193 | Pold2 | 21543 | -0.257 | 0.1865 | No |
| 194 | Tcf19 | 23087 | -0.321 | 0.1361 | No |
| 195 | Hmga1b | 23410 | -0.338 | 0.1307 | No |
| 196 | Myc | 23468 | -0.341 | 0.1350 | No |
| 197 | Dctpp1 | 24533 | -0.405 | 0.1037 | No |
| 198 | Prdx4 | 25115 | -0.441 | 0.0907 | No |

