| Dataset | MEP.MEP.ery_Pheno.cls #Group2_versus_Group4.MEP.ery_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | MEP.ery_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | -0.33523124 |
| Normalized Enrichment Score (NES) | -1.3174562 |
| Nominal p-value | 0.16858238 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.804 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Bcat1 | 10 | 1.633 | 0.0286 | No |
| 2 | Thy1 | 218 | 0.892 | 0.0369 | No |
| 3 | Akt1 | 297 | 0.832 | 0.0488 | No |
| 4 | Cd3d | 371 | 0.797 | 0.0602 | No |
| 5 | Prkcg | 1090 | 0.609 | 0.0448 | No |
| 6 | Ccr2 | 1155 | 0.597 | 0.0531 | No |
| 7 | Mmp9 | 1205 | 0.592 | 0.0618 | No |
| 8 | Nos2 | 1521 | 0.552 | 0.0601 | No |
| 9 | Tlr1 | 1734 | 0.525 | 0.0617 | No |
| 10 | Ly86 | 1743 | 0.524 | 0.0707 | No |
| 11 | Ccr5 | 1829 | 0.515 | 0.0767 | No |
| 12 | Irf8 | 1936 | 0.506 | 0.0819 | No |
| 13 | Igsf6 | 2285 | 0.478 | 0.0776 | No |
| 14 | Abce1 | 2286 | 0.478 | 0.0861 | No |
| 15 | Fasl | 2711 | 0.444 | 0.0786 | No |
| 16 | Brca1 | 2927 | 0.433 | 0.0784 | No |
| 17 | Prkcb | 2946 | 0.431 | 0.0854 | No |
| 18 | Ccr1 | 3107 | 0.420 | 0.0870 | No |
| 19 | Cd86 | 3125 | 0.419 | 0.0938 | No |
| 20 | Ube2n | 3568 | 0.393 | 0.0846 | No |
| 21 | Egfr | 3703 | 0.386 | 0.0866 | No |
| 22 | Eif3a | 3816 | 0.380 | 0.0893 | No |
| 23 | Il12rb1 | 4081 | 0.367 | 0.0861 | No |
| 24 | Il1b | 4091 | 0.367 | 0.0923 | No |
| 25 | Cd3e | 4837 | 0.331 | 0.0710 | No |
| 26 | Klrd1 | 4946 | 0.326 | 0.0729 | No |
| 27 | F2 | 4967 | 0.326 | 0.0779 | No |
| 28 | Ccl5 | 5160 | 0.321 | 0.0766 | No |
| 29 | Timp1 | 5185 | 0.320 | 0.0814 | No |
| 30 | Gcnt1 | 5434 | 0.310 | 0.0779 | No |
| 31 | Irf4 | 5464 | 0.308 | 0.0823 | No |
| 32 | Gpr65 | 5498 | 0.307 | 0.0865 | No |
| 33 | Ache | 5578 | 0.301 | 0.0890 | No |
| 34 | Ncr1 | 5979 | 0.283 | 0.0794 | No |
| 35 | Mrpl3 | 6645 | 0.256 | 0.0597 | No |
| 36 | Rpl3l | 6669 | 0.254 | 0.0634 | No |
| 37 | Traf2 | 6722 | 0.252 | 0.0659 | No |
| 38 | Wars1 | 7004 | 0.239 | 0.0599 | No |
| 39 | Icosl | 7714 | 0.218 | 0.0379 | No |
| 40 | Gzmb | 8097 | 0.205 | 0.0277 | No |
| 41 | Jak2 | 8488 | 0.189 | 0.0168 | No |
| 42 | Nck1 | 8608 | 0.184 | 0.0157 | No |
| 43 | Cd2 | 8714 | 0.180 | 0.0151 | No |
| 44 | Stat1 | 8772 | 0.178 | 0.0162 | No |
| 45 | Cdkn2a | 9004 | 0.169 | 0.0107 | No |
| 46 | Inhba | 9101 | 0.165 | 0.0102 | No |
| 47 | Cd80 | 9317 | 0.162 | 0.0052 | No |
| 48 | Il18rap | 9486 | 0.156 | 0.0018 | No |
| 49 | Eif3j1 | 9572 | 0.152 | 0.0014 | No |
| 50 | Dyrk3 | 9576 | 0.152 | 0.0040 | No |
| 51 | Abi1 | 10756 | 0.115 | -0.0369 | No |
| 52 | Cd4 | 10822 | 0.113 | -0.0373 | No |
| 53 | Eif3d | 10927 | 0.109 | -0.0391 | No |
| 54 | Cfp | 11363 | 0.093 | -0.0534 | No |
| 55 | Ly75 | 12014 | 0.069 | -0.0758 | No |
| 56 | Tlr3 | 12025 | 0.069 | -0.0750 | No |
| 57 | Elane | 12254 | 0.060 | -0.0822 | No |
| 58 | Cd247 | 12340 | 0.056 | -0.0843 | No |
| 59 | Nlrp3 | 12541 | 0.049 | -0.0907 | No |
| 60 | Il18 | 12679 | 0.044 | -0.0950 | No |
| 61 | Eif4g3 | 12977 | 0.033 | -0.1052 | No |
| 62 | Tapbp | 12988 | 0.032 | -0.1050 | No |
| 63 | Ptpn6 | 13154 | 0.027 | -0.1105 | No |
| 64 | Il4ra | 13164 | 0.027 | -0.1104 | No |
| 65 | Was | 13359 | 0.020 | -0.1171 | No |
| 66 | Galnt1 | 13422 | 0.019 | -0.1190 | No |
| 67 | Ctss | 13523 | 0.016 | -0.1224 | No |
| 68 | Crtam | 13727 | 0.009 | -0.1296 | No |
| 69 | Tgfb2 | 13827 | 0.006 | -0.1331 | No |
| 70 | Map3k7 | 14025 | 0.001 | -0.1403 | No |
| 71 | Ereg | 14082 | 0.000 | -0.1423 | No |
| 72 | Cd7 | 14911 | -0.019 | -0.1722 | No |
| 73 | Cd74 | 15101 | -0.025 | -0.1786 | No |
| 74 | Cd28 | 15619 | -0.044 | -0.1967 | No |
| 75 | H2-DMb2 | 16391 | -0.071 | -0.2235 | No |
| 76 | Irf7 | 16405 | -0.072 | -0.2227 | No |
| 77 | Hif1a | 16660 | -0.081 | -0.2306 | No |
| 78 | Cd47 | 16987 | -0.092 | -0.2408 | No |
| 79 | Cd79a | 16993 | -0.092 | -0.2394 | No |
| 80 | Lif | 17411 | -0.108 | -0.2527 | No |
| 81 | Bcl10 | 17549 | -0.112 | -0.2557 | No |
| 82 | Socs5 | 17632 | -0.115 | -0.2566 | No |
| 83 | Npm1 | 17642 | -0.116 | -0.2549 | No |
| 84 | Rpl39-ps | 17668 | -0.116 | -0.2538 | No |
| 85 | Stab1 | 17773 | -0.120 | -0.2554 | No |
| 86 | Il10 | 18179 | -0.134 | -0.2678 | No |
| 87 | Psmb10 | 18386 | -0.143 | -0.2728 | No |
| 88 | Tpd52 | 18510 | -0.147 | -0.2747 | No |
| 89 | Rpl9 | 18613 | -0.150 | -0.2757 | No |
| 90 | Icam1 | 18701 | -0.154 | -0.2762 | No |
| 91 | Csk | 18743 | -0.156 | -0.2749 | No |
| 92 | Ncf4 | 18872 | -0.159 | -0.2767 | No |
| 93 | Ripk2 | 18916 | -0.161 | -0.2755 | No |
| 94 | Cd3g | 18962 | -0.162 | -0.2742 | No |
| 95 | Il11 | 18979 | -0.162 | -0.2719 | No |
| 96 | Mtif2 | 19114 | -0.168 | -0.2738 | No |
| 97 | Bcl3 | 19273 | -0.174 | -0.2765 | No |
| 98 | Nme1 | 19733 | -0.190 | -0.2899 | No |
| 99 | Il4 | 19801 | -0.192 | -0.2889 | No |
| 100 | Map4k1 | 19815 | -0.193 | -0.2860 | No |
| 101 | Tnf | 19855 | -0.194 | -0.2839 | No |
| 102 | Hdac9 | 20083 | -0.203 | -0.2886 | No |
| 103 | H2-Aa | 20088 | -0.203 | -0.2852 | No |
| 104 | Itk | 20185 | -0.207 | -0.2850 | No |
| 105 | Hcls1 | 20286 | -0.211 | -0.2849 | No |
| 106 | Il15 | 20739 | -0.222 | -0.2974 | No |
| 107 | Ikbkb | 20860 | -0.226 | -0.2978 | No |
| 108 | Apbb1 | 20963 | -0.230 | -0.2974 | No |
| 109 | Glmn | 21093 | -0.237 | -0.2979 | No |
| 110 | Flna | 21129 | -0.238 | -0.2950 | No |
| 111 | Acvr2a | 21187 | -0.241 | -0.2928 | No |
| 112 | Degs1 | 21299 | -0.246 | -0.2925 | No |
| 113 | Ets1 | 21524 | -0.256 | -0.2961 | No |
| 114 | Il2rb | 21587 | -0.259 | -0.2938 | No |
| 115 | Il2 | 21840 | -0.267 | -0.2983 | No |
| 116 | Il7 | 21949 | -0.271 | -0.2974 | No |
| 117 | Il27ra | 22176 | -0.282 | -0.3006 | No |
| 118 | Cd40lg | 22915 | -0.314 | -0.3220 | No |
| 119 | Ifngr2 | 23280 | -0.331 | -0.3294 | Yes |
| 120 | Rps3a1 | 23416 | -0.338 | -0.3283 | Yes |
| 121 | Rps9 | 23462 | -0.340 | -0.3239 | Yes |
| 122 | Tlr2 | 23476 | -0.341 | -0.3183 | Yes |
| 123 | Zap70 | 23484 | -0.342 | -0.3125 | Yes |
| 124 | Socs1 | 23497 | -0.342 | -0.3069 | Yes |
| 125 | Ccnd2 | 23924 | -0.367 | -0.3159 | Yes |
| 126 | Cd40 | 23935 | -0.367 | -0.3098 | Yes |
| 127 | Tap2 | 23967 | -0.369 | -0.3044 | Yes |
| 128 | St8sia4 | 24104 | -0.376 | -0.3027 | Yes |
| 129 | Fas | 24240 | -0.386 | -0.3008 | Yes |
| 130 | Tlr6 | 24243 | -0.386 | -0.2940 | Yes |
| 131 | Tap1 | 24249 | -0.386 | -0.2873 | Yes |
| 132 | Prf1 | 24365 | -0.393 | -0.2846 | Yes |
| 133 | Eif5a | 24454 | -0.400 | -0.2807 | Yes |
| 134 | Fcgr2b | 24715 | -0.414 | -0.2828 | Yes |
| 135 | B2m | 24911 | -0.427 | -0.2823 | Yes |
| 136 | Ube2d1 | 25112 | -0.441 | -0.2818 | Yes |
| 137 | Ifnar2 | 25407 | -0.466 | -0.2843 | Yes |
| 138 | Lck | 25545 | -0.480 | -0.2807 | Yes |
| 139 | Ifngr1 | 25570 | -0.482 | -0.2731 | Yes |
| 140 | Il12a | 25896 | -0.515 | -0.2758 | Yes |
| 141 | Itgal | 26001 | -0.526 | -0.2703 | Yes |
| 142 | Trat1 | 26035 | -0.530 | -0.2621 | Yes |
| 143 | Il2ra | 26099 | -0.536 | -0.2549 | Yes |
| 144 | F2r | 26102 | -0.537 | -0.2454 | Yes |
| 145 | Ccnd3 | 26324 | -0.565 | -0.2435 | Yes |
| 146 | Pf4 | 26336 | -0.567 | -0.2338 | Yes |
| 147 | Spi1 | 26504 | -0.592 | -0.2294 | Yes |
| 148 | Il6 | 26567 | -0.602 | -0.2210 | Yes |
| 149 | Itgb2 | 26614 | -0.608 | -0.2119 | Yes |
| 150 | Fgr | 26710 | -0.622 | -0.2043 | Yes |
| 151 | H2-Ob | 26792 | -0.635 | -0.1960 | Yes |
| 152 | Tgfb1 | 26829 | -0.642 | -0.1859 | Yes |
| 153 | Cd1d2 | 26844 | -0.644 | -0.1750 | Yes |
| 154 | H2-DMa | 26921 | -0.663 | -0.1661 | Yes |
| 155 | Capg | 26942 | -0.667 | -0.1550 | Yes |
| 156 | Lyn | 26945 | -0.667 | -0.1432 | Yes |
| 157 | Ptprc | 26995 | -0.679 | -0.1330 | Yes |
| 158 | H2-Oa | 27004 | -0.682 | -0.1212 | Yes |
| 159 | Stat4 | 27042 | -0.691 | -0.1103 | Yes |
| 160 | C2 | 27103 | -0.708 | -0.0999 | Yes |
| 161 | Il2rg | 27203 | -0.742 | -0.0904 | Yes |
| 162 | Csf1 | 27254 | -0.759 | -0.0787 | Yes |
| 163 | Elf4 | 27294 | -0.775 | -0.0664 | Yes |
| 164 | Ltb | 27379 | -0.817 | -0.0550 | Yes |
| 165 | Lcp2 | 27380 | -0.818 | -0.0405 | Yes |
| 166 | Srgn | 27421 | -0.840 | -0.0271 | Yes |
| 167 | Il16 | 27495 | -0.893 | -0.0139 | Yes |
| 168 | Cd96 | 27555 | -1.002 | 0.0017 | Yes |

