| Dataset | MEP.MEP.ery_Pheno.cls #Group2_versus_Group3.MEP.ery_Pheno.cls #Group2_versus_Group3_repos |
| Phenotype | MEP.ery_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.49732238 |
| Normalized Enrichment Score (NES) | 1.9053026 |
| Nominal p-value | 0.009784736 |
| FDR q-value | 0.01089949 |
| FWER p-Value | 0.012 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Srsf1 | 172 | 0.784 | 0.0110 | Yes |
| 2 | Hspa8 | 253 | 0.725 | 0.0241 | Yes |
| 3 | Nek2 | 333 | 0.688 | 0.0364 | Yes |
| 4 | Cdc6 | 353 | 0.680 | 0.0507 | Yes |
| 5 | Hnrnpu | 626 | 0.595 | 0.0539 | Yes |
| 6 | Ccna2 | 640 | 0.592 | 0.0665 | Yes |
| 7 | Lmnb1 | 869 | 0.552 | 0.0704 | Yes |
| 8 | Mcm2 | 963 | 0.536 | 0.0788 | Yes |
| 9 | Hnrnpd | 1118 | 0.512 | 0.0845 | Yes |
| 10 | Nsd2 | 1166 | 0.507 | 0.0940 | Yes |
| 11 | Sap30 | 1346 | 0.493 | 0.0984 | Yes |
| 12 | Nasp | 1378 | 0.488 | 0.1080 | Yes |
| 13 | Ncl | 1419 | 0.484 | 0.1172 | Yes |
| 14 | Aurka | 1675 | 0.450 | 0.1178 | Yes |
| 15 | Smc1a | 1765 | 0.444 | 0.1244 | Yes |
| 16 | Amd1 | 1972 | 0.428 | 0.1263 | Yes |
| 17 | Dr1 | 1977 | 0.428 | 0.1356 | Yes |
| 18 | Xpo1 | 1980 | 0.428 | 0.1450 | Yes |
| 19 | Meis2 | 2029 | 0.423 | 0.1526 | Yes |
| 20 | Cdk1 | 2144 | 0.414 | 0.1576 | Yes |
| 21 | Mcm3 | 2173 | 0.411 | 0.1656 | Yes |
| 22 | Rad21 | 2185 | 0.409 | 0.1742 | Yes |
| 23 | Mcm5 | 2208 | 0.407 | 0.1824 | Yes |
| 24 | Lbr | 2228 | 0.406 | 0.1907 | Yes |
| 25 | Chaf1a | 2312 | 0.400 | 0.1965 | Yes |
| 26 | Bub1 | 2400 | 0.395 | 0.2020 | Yes |
| 27 | Kif4 | 2402 | 0.395 | 0.2107 | Yes |
| 28 | Nolc1 | 2434 | 0.392 | 0.2182 | Yes |
| 29 | Mcm6 | 2497 | 0.387 | 0.2245 | Yes |
| 30 | Odc1 | 2569 | 0.384 | 0.2304 | Yes |
| 31 | Mybl2 | 2625 | 0.381 | 0.2368 | Yes |
| 32 | Hmgb3 | 2656 | 0.379 | 0.2440 | Yes |
| 33 | Racgap1 | 2731 | 0.374 | 0.2496 | Yes |
| 34 | Prpf4b | 2852 | 0.366 | 0.2533 | Yes |
| 35 | Cdc25a | 3085 | 0.351 | 0.2526 | Yes |
| 36 | Ythdc1 | 3131 | 0.348 | 0.2586 | Yes |
| 37 | Cks2 | 3137 | 0.347 | 0.2661 | Yes |
| 38 | Srsf10 | 3146 | 0.347 | 0.2734 | Yes |
| 39 | Kif22 | 3336 | 0.338 | 0.2740 | Yes |
| 40 | Kpnb1 | 3386 | 0.334 | 0.2796 | Yes |
| 41 | Prmt5 | 3584 | 0.325 | 0.2796 | Yes |
| 42 | Tent4a | 3683 | 0.322 | 0.2831 | Yes |
| 43 | Prc1 | 3720 | 0.321 | 0.2889 | Yes |
| 44 | Upf1 | 3977 | 0.307 | 0.2863 | Yes |
| 45 | Ddx39a | 4015 | 0.305 | 0.2917 | Yes |
| 46 | Cdkn2c | 4039 | 0.303 | 0.2975 | Yes |
| 47 | Sfpq | 4122 | 0.299 | 0.3011 | Yes |
| 48 | Tfdp1 | 4158 | 0.298 | 0.3064 | Yes |
| 49 | Tmpo | 4164 | 0.297 | 0.3128 | Yes |
| 50 | Cul4a | 4268 | 0.292 | 0.3155 | Yes |
| 51 | Kif2c | 4298 | 0.291 | 0.3208 | Yes |
| 52 | Plk4 | 4319 | 0.289 | 0.3265 | Yes |
| 53 | Pbk | 4321 | 0.289 | 0.3328 | Yes |
| 54 | Cul1 | 4322 | 0.289 | 0.3392 | Yes |
| 55 | Mki67 | 4346 | 0.288 | 0.3447 | Yes |
| 56 | Top2a | 4440 | 0.284 | 0.3476 | Yes |
| 57 | Kif11 | 4441 | 0.284 | 0.3538 | Yes |
| 58 | Bard1 | 4445 | 0.284 | 0.3600 | Yes |
| 59 | Polq | 4488 | 0.281 | 0.3647 | Yes |
| 60 | Tra2b | 4510 | 0.280 | 0.3701 | Yes |
| 61 | Orc5 | 4628 | 0.276 | 0.3719 | Yes |
| 62 | Prim2 | 4679 | 0.275 | 0.3761 | Yes |
| 63 | Cenpe | 4680 | 0.274 | 0.3822 | Yes |
| 64 | Suv39h1 | 4722 | 0.272 | 0.3867 | Yes |
| 65 | Fbxo5 | 4772 | 0.270 | 0.3909 | Yes |
| 66 | Tpx2 | 4783 | 0.270 | 0.3965 | Yes |
| 67 | Ttk | 4794 | 0.269 | 0.4020 | Yes |
| 68 | Cul3 | 5061 | 0.257 | 0.3980 | Yes |
| 69 | Mad2l1 | 5067 | 0.256 | 0.4035 | Yes |
| 70 | Hus1 | 5071 | 0.256 | 0.4090 | Yes |
| 71 | Top1 | 5337 | 0.244 | 0.4047 | Yes |
| 72 | Wrn | 5445 | 0.239 | 0.4061 | Yes |
| 73 | Syncrip | 5455 | 0.239 | 0.4110 | Yes |
| 74 | Tacc3 | 5490 | 0.237 | 0.4150 | Yes |
| 75 | Chek1 | 5506 | 0.237 | 0.4197 | Yes |
| 76 | Incenp | 5611 | 0.233 | 0.4210 | Yes |
| 77 | E2f4 | 5625 | 0.232 | 0.4257 | Yes |
| 78 | G3bp1 | 5749 | 0.229 | 0.4263 | Yes |
| 79 | Hira | 5780 | 0.228 | 0.4302 | Yes |
| 80 | Odf2 | 5791 | 0.228 | 0.4349 | Yes |
| 81 | Pole | 5798 | 0.227 | 0.4397 | Yes |
| 82 | Rbl1 | 5895 | 0.223 | 0.4411 | Yes |
| 83 | E2f2 | 5999 | 0.221 | 0.4422 | Yes |
| 84 | E2f1 | 6001 | 0.221 | 0.4471 | Yes |
| 85 | Pola2 | 6031 | 0.219 | 0.4509 | Yes |
| 86 | Numa1 | 6041 | 0.219 | 0.4554 | Yes |
| 87 | Cenpf | 6042 | 0.219 | 0.4602 | Yes |
| 88 | Cdc7 | 6131 | 0.216 | 0.4617 | Yes |
| 89 | Kif23 | 6140 | 0.215 | 0.4662 | Yes |
| 90 | Pafah1b1 | 6219 | 0.212 | 0.4680 | Yes |
| 91 | Hmmr | 6267 | 0.211 | 0.4710 | Yes |
| 92 | Cul5 | 6277 | 0.211 | 0.4753 | Yes |
| 93 | Tnpo2 | 6561 | 0.201 | 0.4694 | Yes |
| 94 | Rad54l | 6599 | 0.200 | 0.4725 | Yes |
| 95 | H2az1 | 6698 | 0.195 | 0.4732 | Yes |
| 96 | Uck2 | 6880 | 0.188 | 0.4708 | Yes |
| 97 | E2f3 | 6895 | 0.188 | 0.4744 | Yes |
| 98 | Ezh2 | 6977 | 0.184 | 0.4755 | Yes |
| 99 | Tle3 | 6983 | 0.184 | 0.4794 | Yes |
| 100 | Smarcc1 | 7042 | 0.181 | 0.4812 | Yes |
| 101 | Cdkn1b | 7048 | 0.181 | 0.4851 | Yes |
| 102 | Casp8ap2 | 7153 | 0.177 | 0.4852 | Yes |
| 103 | Smc2 | 7266 | 0.173 | 0.4849 | Yes |
| 104 | Pml | 7357 | 0.169 | 0.4853 | Yes |
| 105 | Ccnf | 7363 | 0.169 | 0.4889 | Yes |
| 106 | Ube2s | 7385 | 0.168 | 0.4918 | Yes |
| 107 | Brca2 | 7439 | 0.166 | 0.4936 | Yes |
| 108 | Cdc27 | 7605 | 0.164 | 0.4912 | Yes |
| 109 | Ccnt1 | 7714 | 0.160 | 0.4908 | Yes |
| 110 | Kif15 | 7778 | 0.158 | 0.4919 | Yes |
| 111 | Kif5b | 7894 | 0.154 | 0.4911 | Yes |
| 112 | Plk1 | 7967 | 0.151 | 0.4918 | Yes |
| 113 | Orc6 | 8061 | 0.148 | 0.4917 | Yes |
| 114 | Mtf2 | 8128 | 0.145 | 0.4925 | Yes |
| 115 | Birc5 | 8228 | 0.142 | 0.4920 | Yes |
| 116 | Smc4 | 8252 | 0.142 | 0.4943 | Yes |
| 117 | Gspt1 | 8256 | 0.141 | 0.4973 | Yes |
| 118 | Espl1 | 8439 | 0.139 | 0.4938 | No |
| 119 | Abl1 | 8617 | 0.133 | 0.4902 | No |
| 120 | Ilf3 | 8668 | 0.132 | 0.4913 | No |
| 121 | Rpa2 | 8770 | 0.129 | 0.4905 | No |
| 122 | H2bc12 | 8792 | 0.128 | 0.4925 | No |
| 123 | Ndc80 | 8868 | 0.126 | 0.4926 | No |
| 124 | Fancc | 8872 | 0.125 | 0.4952 | No |
| 125 | Arid4a | 8967 | 0.122 | 0.4945 | No |
| 126 | Exo1 | 9195 | 0.115 | 0.4888 | No |
| 127 | Ctcf | 9280 | 0.113 | 0.4882 | No |
| 128 | Dkc1 | 9281 | 0.113 | 0.4907 | No |
| 129 | Stag1 | 9359 | 0.110 | 0.4903 | No |
| 130 | Aurkb | 9810 | 0.095 | 0.4760 | No |
| 131 | Dbf4 | 9877 | 0.093 | 0.4756 | No |
| 132 | Snrpd1 | 9896 | 0.093 | 0.4770 | No |
| 133 | Cdc45 | 9937 | 0.092 | 0.4776 | No |
| 134 | Kmt5a | 10117 | 0.086 | 0.4730 | No |
| 135 | Rad23b | 10124 | 0.086 | 0.4746 | No |
| 136 | Stmn1 | 10136 | 0.085 | 0.4761 | No |
| 137 | Atrx | 10248 | 0.082 | 0.4739 | No |
| 138 | Cbx1 | 10284 | 0.081 | 0.4744 | No |
| 139 | Pds5b | 10456 | 0.076 | 0.4698 | No |
| 140 | Mapk14 | 10537 | 0.074 | 0.4685 | No |
| 141 | Hmga1b | 10955 | 0.060 | 0.4547 | No |
| 142 | Smad3 | 11060 | 0.057 | 0.4521 | No |
| 143 | Notch2 | 11099 | 0.056 | 0.4520 | No |
| 144 | Ss18 | 11172 | 0.053 | 0.4505 | No |
| 145 | Knl1 | 11487 | 0.044 | 0.4400 | No |
| 146 | Kif20b | 11607 | 0.040 | 0.4366 | No |
| 147 | Slc7a1 | 11706 | 0.037 | 0.4338 | No |
| 148 | Lig3 | 11775 | 0.035 | 0.4321 | No |
| 149 | Slc38a1 | 11938 | 0.030 | 0.4269 | No |
| 150 | Efna5 | 11972 | 0.029 | 0.4263 | No |
| 151 | Nup98 | 12228 | 0.022 | 0.4175 | No |
| 152 | Map3k20 | 12321 | 0.018 | 0.4145 | No |
| 153 | Cks1b | 12434 | 0.016 | 0.4108 | No |
| 154 | Stil | 12614 | 0.011 | 0.4045 | No |
| 155 | Traip | 12685 | 0.009 | 0.4022 | No |
| 156 | Nup50 | 13280 | -0.003 | 0.3806 | No |
| 157 | Gins2 | 13566 | -0.012 | 0.3704 | No |
| 158 | Bcl3 | 13850 | -0.020 | 0.3606 | No |
| 159 | Rasal2 | 14058 | -0.026 | 0.3536 | No |
| 160 | Nusap1 | 14385 | -0.035 | 0.3425 | No |
| 161 | Dtymk | 14428 | -0.036 | 0.3417 | No |
| 162 | Ewsr1 | 14638 | -0.043 | 0.3350 | No |
| 163 | Chmp1a | 14678 | -0.044 | 0.3346 | No |
| 164 | Katna1 | 14885 | -0.050 | 0.3282 | No |
| 165 | Atf5 | 15065 | -0.055 | 0.3228 | No |
| 166 | Rps6ka5 | 15210 | -0.059 | 0.3189 | No |
| 167 | Ccnb2 | 15235 | -0.059 | 0.3193 | No |
| 168 | Jpt1 | 15713 | -0.074 | 0.3035 | No |
| 169 | Cenpa | 15878 | -0.079 | 0.2993 | No |
| 170 | Pura | 16115 | -0.087 | 0.2926 | No |
| 171 | Sqle | 16459 | -0.097 | 0.2822 | No |
| 172 | Cdk4 | 16839 | -0.108 | 0.2708 | No |
| 173 | Srsf2 | 17056 | -0.115 | 0.2654 | No |
| 174 | H2az2 | 17129 | -0.117 | 0.2654 | No |
| 175 | Cdc20 | 17348 | -0.124 | 0.2602 | No |
| 176 | Hif1a | 17641 | -0.134 | 0.2524 | No |
| 177 | Slc12a2 | 17791 | -0.139 | 0.2501 | No |
| 178 | Mnat1 | 18432 | -0.158 | 0.2302 | No |
| 179 | Slc7a5 | 18623 | -0.164 | 0.2269 | No |
| 180 | Myc | 18830 | -0.170 | 0.2231 | No |
| 181 | H2ax | 19759 | -0.201 | 0.1937 | No |
| 182 | Bub3 | 19776 | -0.202 | 0.1976 | No |
| 183 | Troap | 19989 | -0.210 | 0.1945 | No |
| 184 | Foxn3 | 20153 | -0.215 | 0.1933 | No |
| 185 | Ube2c | 20302 | -0.219 | 0.1927 | No |
| 186 | Cdc25b | 20336 | -0.220 | 0.1963 | No |
| 187 | Egf | 21232 | -0.254 | 0.1693 | No |
| 188 | Dmd | 21701 | -0.272 | 0.1582 | No |
| 189 | Pttg1 | 22010 | -0.286 | 0.1533 | No |
| 190 | Ccnd1 | 23023 | -0.327 | 0.1236 | No |
| 191 | Marcks | 24402 | -0.401 | 0.0822 | No |
| 192 | Cdkn3 | 25313 | -0.458 | 0.0591 | No |
| 193 | Meis1 | 25751 | -0.493 | 0.0540 | No |
| 194 | Tgfb1 | 26704 | -0.611 | 0.0328 | No |

