Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	MEP.MEP.ery_Pheno.cls #Group1_versus_Group4.MEP.ery_Pheno.cls #Group1_versus_Group4_repos
Phenotype	MEP.ery_Pheno.cls#Group1_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.23134239
Normalized Enrichment Score (NES)	-1.2254
Nominal p-value	0.23608445
FDR q-value	0.49147767
FWER p-Value	0.945

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Akt1	1931	0.469	-0.0518	No
2	Ppp2r1b	2031	0.460	-0.0372	No
3	Prkcb	2060	0.458	-0.0202	No
4	Egfr	2118	0.451	-0.0045	No
5	Fgf17	2356	0.432	0.0039	No
6	Cltc	2408	0.430	0.0190	No
7	Traf2	2800	0.398	0.0204	No
8	Ube2n	2876	0.396	0.0333	No
9	Hsp90b1	2974	0.389	0.0451	No
10	Pik3r3	3079	0.383	0.0564	No
11	Mknk2	4682	0.308	0.0103	No
12	Calr	4713	0.307	0.0213	No
13	Rptor	4836	0.301	0.0287	No
14	Pikfyve	4908	0.296	0.0377	No
15	Cdk1	5384	0.278	0.0314	No
16	Tsc2	5513	0.270	0.0374	No
17	Pdk1	5555	0.268	0.0465	No
18	Plcb1	5614	0.265	0.0548	No
19	Sfn	5731	0.260	0.0608	No
20	Actr2	5745	0.259	0.0706	No
21	Ptpn11	5948	0.249	0.0730	No
22	Fasl	6630	0.225	0.0571	No
23	Map3k7	7041	0.212	0.0506	No
24	Mapk9	7125	0.208	0.0558	No
25	E2f1	7363	0.200	0.0550	No
26	Adcy2	7497	0.194	0.0578	No
27	Actr3	7703	0.186	0.0577	No
28	Myd88	8217	0.166	0.0456	No
29	Nck1	9026	0.149	0.0221	No
30	Cab39	9105	0.145	0.0249	No
31	Mknk1	9192	0.143	0.0274	No
32	Eif4e	9438	0.134	0.0238	No
33	Pten	9453	0.134	0.0286	No
34	Atf1	9496	0.132	0.0323	No
35	Camk4	9575	0.130	0.0345	No
36	Prkar2a	9649	0.128	0.0369	No
37	Mapk1	9864	0.121	0.0339	No
38	Arf1	10040	0.116	0.0321	No
39	Tbk1	10185	0.111	0.0312	No
40	Raf1	10343	0.106	0.0297	No
41	Pak4	10538	0.099	0.0265	No
42	Acaca	10662	0.094	0.0258	No
43	Tiam1	10695	0.093	0.0283	No
44	Smad2	10995	0.084	0.0207	No
45	Pla2g12a	11007	0.083	0.0236	No
46	Mapkap1	11247	0.074	0.0178	No
47	Pin1	11512	0.066	0.0108	No
48	Mapk8	11611	0.062	0.0097	No
49	Gsk3b	11916	0.052	0.0007	No
50	Ngf	13025	0.016	-0.0390	No
51	Fgf6	13757	0.000	-0.0656	No
52	Cab39l	14212	-0.002	-0.0820	No
53	Map2k6	14343	-0.006	-0.0865	No
54	Ube2d3	14685	-0.017	-0.0982	No
55	Stat2	14822	-0.023	-0.1023	No
56	Plcg1	14856	-0.024	-0.1025	No
57	Prkaa2	14875	-0.025	-0.1022	No
58	Cdk2	15298	-0.040	-0.1159	No
59	Ap2m1	15303	-0.041	-0.1145	No
60	Prkag1	15715	-0.053	-0.1273	No
61	Ywhab	15744	-0.054	-0.1262	No
62	Akt1s1	16667	-0.081	-0.1566	No
63	Them4	16695	-0.082	-0.1543	No
64	Cdkn1b	16875	-0.089	-0.1573	No
65	Arpc3	17068	-0.096	-0.1605	No
66	Grb2	17099	-0.097	-0.1578	No
67	Fgf22	17562	-0.114	-0.1701	No
68	Arhgdia	17583	-0.115	-0.1663	No
69	Gna14	18659	-0.149	-0.1995	No
70	Ddit3	18680	-0.149	-0.1944	No
71	Ripk1	18855	-0.156	-0.1946	No
72	Grk2	19007	-0.162	-0.1937	No
73	Mapk10	19152	-0.168	-0.1923	No
74	Hras	19982	-0.198	-0.2147	No
75	Rps6ka1	20297	-0.210	-0.2178	No
76	Sla	20466	-0.216	-0.2154	No
77	Rps6ka3	20775	-0.222	-0.2179	Yes
78	Sqstm1	20875	-0.226	-0.2126	Yes
79	Cxcr4	20935	-0.229	-0.2057	Yes
80	Lck	21535	-0.253	-0.2175	Yes
81	Itpr2	21632	-0.258	-0.2109	Yes
82	Pitx2	21682	-0.260	-0.2024	Yes
83	Map2k3	21830	-0.261	-0.1975	Yes
84	Rit1	22134	-0.275	-0.1977	Yes
85	Slc2a1	22696	-0.297	-0.2063	Yes
86	Cdk4	23242	-0.320	-0.2136	Yes
87	Irak4	23732	-0.345	-0.2177	Yes
88	Ecsit	23735	-0.346	-0.2042	Yes
89	Nod1	24169	-0.367	-0.2055	Yes
90	Rac1	24307	-0.373	-0.1957	Yes
91	Vav3	24468	-0.381	-0.1866	Yes
92	Dusp3	24520	-0.384	-0.1733	Yes
93	Ralb	24759	-0.400	-0.1662	Yes
94	Nfkbib	24859	-0.407	-0.1538	Yes
95	Il4	25329	-0.432	-0.1538	Yes
96	Pfn1	26294	-0.514	-0.1686	Yes
97	Tnfrsf1a	26647	-0.559	-0.1594	Yes
98	Trib3	26777	-0.579	-0.1413	Yes
99	Dapp1	26797	-0.585	-0.1189	Yes
100	Csnk2b	26901	-0.604	-0.0989	Yes
101	Ppp1ca	27292	-0.710	-0.0851	Yes
102	Il2rg	27400	-0.765	-0.0589	Yes
103	Cfl1	27437	-0.794	-0.0289	Yes
104	Cdkn1a	27527	-0.885	0.0027	Yes