Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	MEP.MEP.ery_Pheno.cls #Group1_versus_Group4.MEP.ery_Pheno.cls #Group1_versus_Group4_repos
Phenotype	MEP.ery_Pheno.cls#Group1_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.31449664
Normalized Enrichment Score (NES)	-1.35577
Nominal p-value	0.11022044
FDR q-value	0.46542743
FWER p-Value	0.772

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Cd82	599	0.665	-0.0097	No
2	Clca2	736	0.629	-0.0031	No
3	Rxra	778	0.618	0.0067	No
4	Stom	880	0.599	0.0140	No
5	Epha2	998	0.578	0.0203	No
6	Plk3	1331	0.530	0.0179	No
7	Ccp110	1374	0.526	0.0259	No
8	Slc35d1	1384	0.525	0.0352	No
9	Fgf13	1458	0.517	0.0420	No
10	Fos	1465	0.516	0.0512	No
11	Tgfa	1653	0.495	0.0535	No
12	Upp1	1832	0.479	0.0558	No
13	Jun	1951	0.467	0.0600	No
14	Serpinb5	2025	0.462	0.0658	No
15	Slc19a2	2645	0.414	0.0508	No
16	Ephx1	2981	0.388	0.0457	No
17	Aen	3444	0.365	0.0355	No
18	Nudt15	3618	0.358	0.0357	No
19	Tob1	3671	0.355	0.0403	No
20	Tchh	3698	0.354	0.0459	No
21	Rb1	3741	0.351	0.0508	No
22	Ak1	3941	0.338	0.0497	No
23	Hexim1	3976	0.336	0.0546	No
24	Rad51c	4342	0.322	0.0472	No
25	Klf4	4645	0.311	0.0419	No
26	Il1a	4675	0.309	0.0465	No
27	Mknk2	4682	0.308	0.0519	No
28	Zmat3	4830	0.301	0.0520	No
29	Perp	5118	0.287	0.0468	No
30	Fbxw7	5216	0.282	0.0484	No
31	Foxo3	5363	0.279	0.0482	No
32	Ctsd	5600	0.265	0.0445	No
33	Sfn	5731	0.260	0.0445	No
34	Abcc5	5757	0.259	0.0483	No
35	Cdh13	5766	0.258	0.0527	No
36	Gls2	6202	0.238	0.0412	No
37	Elp1	6307	0.233	0.0417	No
38	H2ac25	6311	0.233	0.0459	No
39	Cyfip2	6351	0.231	0.0487	No
40	Rgs16	6550	0.229	0.0456	No
41	Slc3a2	6566	0.228	0.0493	No
42	Rhbdf2	6867	0.220	0.0423	No
43	Hspa4l	6877	0.220	0.0460	No
44	Traf4	6900	0.219	0.0492	No
45	Pvt1	7009	0.214	0.0492	No
46	Pcna	7059	0.211	0.0513	No
47	Polh	7261	0.204	0.0477	No
48	Ddb2	7875	0.179	0.0286	No
49	Mxd1	7958	0.176	0.0288	No
50	Hbegf	8005	0.175	0.0304	No
51	Sp1	8058	0.172	0.0316	No
52	Csrnp2	8241	0.165	0.0280	No
53	Wwp1	8437	0.157	0.0238	No
54	Tm4sf1	8515	0.155	0.0238	No
55	Blcap	9029	0.149	0.0078	No
56	Ada	9132	0.144	0.0067	No
57	Bmp2	9173	0.143	0.0079	No
58	Lif	9494	0.132	-0.0014	No
59	Rap2b	9532	0.131	-0.0003	No
60	Tsc22d1	9605	0.129	-0.0006	No
61	Ralgds	9889	0.121	-0.0087	No
62	Sphk1	9923	0.119	-0.0077	No
63	Itgb4	10041	0.116	-0.0099	No
64	Cdkn2aip	10303	0.107	-0.0174	No
65	Notch1	10766	0.091	-0.0326	No
66	Slc7a11	10794	0.090	-0.0320	No
67	Cdk5r1	10919	0.086	-0.0349	No
68	Sesn1	10963	0.085	-0.0349	No
69	H1f2	10971	0.084	-0.0336	No
70	Irag2	10986	0.084	-0.0326	No
71	Hmox1	11634	0.061	-0.0551	No
72	Cdkn2b	11635	0.061	-0.0540	No
73	Pidd1	11661	0.060	-0.0538	No
74	Rad9a	11717	0.059	-0.0547	No
75	Osgin1	11768	0.057	-0.0555	No
76	Mdm2	11804	0.056	-0.0557	No
77	Rnf19b	11825	0.056	-0.0554	No
78	Coq8a	11880	0.054	-0.0564	No
79	Plk2	11893	0.053	-0.0559	No
80	Cd81	12028	0.049	-0.0599	No
81	Kif13b	12220	0.042	-0.0661	No
82	Tspyl2	12319	0.038	-0.0690	No
83	Nol8	12412	0.035	-0.0717	No
84	Steap3	12420	0.035	-0.0713	No
85	Pom121	13188	0.012	-0.0990	No
86	Tm7sf3	13365	0.007	-0.1053	No
87	S100a4	13758	0.000	-0.1196	No
88	Xpc	14318	-0.005	-0.1399	No
89	Ip6k2	14379	-0.007	-0.1420	No
90	Ercc5	14494	-0.011	-0.1459	No
91	Ei24	14629	-0.016	-0.1506	No
92	Phlda3	14630	-0.016	-0.1503	No
93	Vwa5a	14802	-0.022	-0.1561	No
94	Retsat	14996	-0.030	-0.1626	No
95	Prkab1	15111	-0.033	-0.1661	No
96	Ccnk	15555	-0.049	-0.1814	No
97	Tnni1	15620	-0.051	-0.1828	No
98	Vdr	16025	-0.062	-0.1964	No
99	Btg2	16173	-0.067	-0.2006	No
100	Rchy1	16586	-0.078	-0.2142	No
101	Apaf1	16635	-0.080	-0.2144	No
102	Ppm1d	16901	-0.090	-0.2225	No
103	Rab40c	16959	-0.092	-0.2229	No
104	Fam162a	16990	-0.093	-0.2223	No
105	Fuca1	17042	-0.095	-0.2224	No
106	Trafd1	17114	-0.098	-0.2232	No
107	Hdac3	17312	-0.105	-0.2285	No
108	Abhd4	17396	-0.108	-0.2295	No
109	Klk8	17653	-0.118	-0.2367	No
110	Jag2	17736	-0.121	-0.2374	No
111	Ccng1	17843	-0.125	-0.2390	No
112	Baiap2	18376	-0.138	-0.2559	No
113	Dgka	18507	-0.143	-0.2580	No
114	Ldhb	18526	-0.144	-0.2560	No
115	Wrap73	18548	-0.145	-0.2542	No
116	Ppp1r15a	18563	-0.145	-0.2520	No
117	Ddit3	18680	-0.149	-0.2535	No
118	F2r	18815	-0.155	-0.2556	No
119	Sat1	19214	-0.170	-0.2670	No
120	Dram1	19365	-0.177	-0.2692	No
121	Cdkn2a	19613	-0.188	-0.2748	No
122	Acvr1b	19661	-0.189	-0.2730	No
123	Hras	19982	-0.198	-0.2811	No
124	Fdxr	19992	-0.198	-0.2778	No
125	Txnip	20096	-0.202	-0.2778	No
126	Bax	20389	-0.213	-0.2846	No
127	Iscu	20796	-0.222	-0.2953	No
128	Tap1	20823	-0.223	-0.2922	No
129	Ddit4	20884	-0.227	-0.2902	No
130	Zbtb16	20892	-0.227	-0.2863	No
131	Cgrrf1	20908	-0.228	-0.2827	No
132	Ctsf	21077	-0.234	-0.2845	No
133	Dnttip2	21089	-0.235	-0.2806	No
134	Prmt2	21194	-0.240	-0.2801	No
135	Ifi30	21289	-0.243	-0.2790	No
136	Eps8l2	21331	-0.245	-0.2761	No
137	Mapkapk3	21383	-0.247	-0.2734	No
138	Plxnb2	21951	-0.267	-0.2892	No
139	Tprkb	22363	-0.284	-0.2990	No
140	Tax1bp3	22789	-0.301	-0.3090	Yes
141	Procr	22802	-0.302	-0.3039	Yes
142	Bak1	23042	-0.313	-0.3069	Yes
143	Alox8	23048	-0.313	-0.3013	Yes
144	Btg1	23207	-0.318	-0.3013	Yes
145	Rrp8	23230	-0.319	-0.2962	Yes
146	Pitpnc1	23244	-0.320	-0.2909	Yes
147	Zfp36l1	23271	-0.322	-0.2859	Yes
148	Trp53	23343	-0.326	-0.2825	Yes
149	Gadd45a	23618	-0.339	-0.2863	Yes
150	Rps12	23658	-0.341	-0.2815	Yes
151	Ptpn14	23729	-0.345	-0.2777	Yes
152	Triap1	23775	-0.348	-0.2730	Yes
153	Tnfsf9	23780	-0.349	-0.2668	Yes
154	Pmm1	23916	-0.356	-0.2652	Yes
155	St14	23960	-0.358	-0.2602	Yes
156	Trp63	24059	-0.363	-0.2571	Yes
157	Pdgfa	24367	-0.375	-0.2615	Yes
158	Zfp365	24369	-0.375	-0.2546	Yes
159	Sdc1	24421	-0.377	-0.2496	Yes
160	Def6	24487	-0.382	-0.2449	Yes
161	Sec61a1	24728	-0.398	-0.2464	Yes
162	Hint1	25041	-0.414	-0.2502	Yes
163	Irak1	25242	-0.427	-0.2497	Yes
164	Casp1	25284	-0.429	-0.2433	Yes
165	Tcn2	25495	-0.444	-0.2429	Yes
166	Rpl18	25570	-0.449	-0.2373	Yes
167	Cebpa	25627	-0.452	-0.2311	Yes
168	Sertad3	25632	-0.452	-0.2230	Yes
169	Ankra2	25745	-0.463	-0.2186	Yes
170	Ndrg1	25771	-0.465	-0.2110	Yes
171	Rrad	25776	-0.466	-0.2026	Yes
172	Ier3	25854	-0.473	-0.1967	Yes
173	Atf3	25861	-0.473	-0.1883	Yes
174	Tgfb1	25986	-0.486	-0.1839	Yes
175	Nupr1	26005	-0.487	-0.1757	Yes
176	H2aj	26089	-0.495	-0.1696	Yes
177	Rpl36	26110	-0.496	-0.1613	Yes
178	Ier5	26148	-0.500	-0.1535	Yes
179	Ptpre	26171	-0.503	-0.1451	Yes
180	Dcxr	26612	-0.553	-0.1510	Yes
181	Vamp8	26613	-0.553	-0.1409	Yes
182	Abat	26615	-0.554	-0.1308	Yes
183	Gm2a	26643	-0.558	-0.1215	Yes
184	Rack1	26682	-0.566	-0.1126	Yes
185	Rps27l	26716	-0.571	-0.1033	Yes
186	Socs1	26766	-0.578	-0.0945	Yes
187	Trib3	26777	-0.579	-0.0843	Yes
188	Ninj1	26824	-0.590	-0.0752	Yes
189	Ccnd2	26874	-0.597	-0.0660	Yes
190	Tpd52l1	26936	-0.611	-0.0571	Yes
191	Ccnd3	27146	-0.663	-0.0525	Yes
192	Fas	27259	-0.696	-0.0439	Yes
193	App	27322	-0.724	-0.0329	Yes
194	Mxd4	27328	-0.727	-0.0198	Yes
195	S100a10	27351	-0.737	-0.0071	Yes
196	Cdkn1a	27527	-0.885	0.0027	Yes