| Dataset | MEP.MEP.ery_Pheno.cls #Group1_versus_Group4.MEP.ery_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | MEP.ery_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.41961065 |
| Normalized Enrichment Score (NES) | 1.4123057 |
| Nominal p-value | 0.1744186 |
| FDR q-value | 0.63778096 |
| FWER p-Value | 0.67 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ccnd1 | 73 | 1.031 | 0.0187 | Yes |
| 2 | Sqle | 307 | 0.779 | 0.0263 | Yes |
| 3 | Nek2 | 724 | 0.632 | 0.0242 | Yes |
| 4 | Kpnb1 | 777 | 0.619 | 0.0351 | Yes |
| 5 | Bard1 | 838 | 0.607 | 0.0455 | Yes |
| 6 | Hnrnpd | 840 | 0.607 | 0.0580 | Yes |
| 7 | Xpo1 | 907 | 0.592 | 0.0678 | Yes |
| 8 | Rad21 | 960 | 0.585 | 0.0780 | Yes |
| 9 | Mcm5 | 1189 | 0.549 | 0.0811 | Yes |
| 10 | Mcm2 | 1268 | 0.539 | 0.0894 | Yes |
| 11 | Chaf1a | 1468 | 0.515 | 0.0928 | Yes |
| 12 | Hnrnpu | 1474 | 0.514 | 0.1032 | Yes |
| 13 | Espl1 | 1490 | 0.512 | 0.1133 | Yes |
| 14 | Upf1 | 1513 | 0.508 | 0.1230 | Yes |
| 15 | H2bc12 | 1611 | 0.500 | 0.1298 | Yes |
| 16 | Lmnb1 | 1698 | 0.491 | 0.1368 | Yes |
| 17 | Dr1 | 1870 | 0.474 | 0.1404 | Yes |
| 18 | Lbr | 1925 | 0.469 | 0.1481 | Yes |
| 19 | Srsf1 | 1932 | 0.468 | 0.1576 | Yes |
| 20 | Tfdp1 | 1988 | 0.464 | 0.1652 | Yes |
| 21 | Amd1 | 2111 | 0.452 | 0.1701 | Yes |
| 22 | Cdc6 | 2169 | 0.445 | 0.1772 | Yes |
| 23 | Nsd2 | 2232 | 0.437 | 0.1840 | Yes |
| 24 | Incenp | 2294 | 0.435 | 0.1907 | Yes |
| 25 | Cdkn2c | 2317 | 0.434 | 0.1989 | Yes |
| 26 | Mcm3 | 2374 | 0.432 | 0.2058 | Yes |
| 27 | Mcm6 | 2450 | 0.429 | 0.2119 | Yes |
| 28 | Odc1 | 2702 | 0.408 | 0.2112 | Yes |
| 29 | Hspa8 | 2715 | 0.406 | 0.2192 | Yes |
| 30 | Sfpq | 2774 | 0.401 | 0.2254 | Yes |
| 31 | Cenpf | 2898 | 0.394 | 0.2290 | Yes |
| 32 | Ccnf | 2949 | 0.391 | 0.2353 | Yes |
| 33 | Mybl2 | 3047 | 0.386 | 0.2397 | Yes |
| 34 | Exo1 | 3274 | 0.376 | 0.2393 | Yes |
| 35 | Ube2s | 3540 | 0.362 | 0.2371 | Yes |
| 36 | Rbl1 | 3715 | 0.353 | 0.2380 | Yes |
| 37 | E2f2 | 3765 | 0.350 | 0.2435 | Yes |
| 38 | Polq | 3825 | 0.345 | 0.2485 | Yes |
| 39 | Cdc25a | 3828 | 0.345 | 0.2555 | Yes |
| 40 | Syncrip | 3873 | 0.342 | 0.2610 | Yes |
| 41 | Prim2 | 3974 | 0.336 | 0.2643 | Yes |
| 42 | Numa1 | 4123 | 0.335 | 0.2659 | Yes |
| 43 | Kif2c | 4207 | 0.330 | 0.2697 | Yes |
| 44 | Top2a | 4336 | 0.322 | 0.2717 | Yes |
| 45 | Egf | 4484 | 0.316 | 0.2728 | Yes |
| 46 | Kif11 | 4513 | 0.315 | 0.2783 | Yes |
| 47 | Slc12a2 | 4611 | 0.312 | 0.2812 | Yes |
| 48 | Pole | 4636 | 0.311 | 0.2868 | Yes |
| 49 | Tra2b | 4650 | 0.310 | 0.2927 | Yes |
| 50 | Bub1 | 4663 | 0.309 | 0.2987 | Yes |
| 51 | Prc1 | 4685 | 0.308 | 0.3043 | Yes |
| 52 | Cul1 | 4687 | 0.308 | 0.3107 | Yes |
| 53 | Smc1a | 4732 | 0.305 | 0.3154 | Yes |
| 54 | Nasp | 4781 | 0.303 | 0.3199 | Yes |
| 55 | Uck2 | 4788 | 0.303 | 0.3259 | Yes |
| 56 | G3bp1 | 4853 | 0.300 | 0.3298 | Yes |
| 57 | Tent4a | 4871 | 0.298 | 0.3354 | Yes |
| 58 | Ewsr1 | 5006 | 0.292 | 0.3365 | Yes |
| 59 | Cdc45 | 5049 | 0.290 | 0.3410 | Yes |
| 60 | Nup98 | 5078 | 0.289 | 0.3459 | Yes |
| 61 | E2f3 | 5158 | 0.285 | 0.3489 | Yes |
| 62 | Nup50 | 5173 | 0.284 | 0.3543 | Yes |
| 63 | Chek1 | 5213 | 0.282 | 0.3587 | Yes |
| 64 | Cdk1 | 5384 | 0.278 | 0.3582 | Yes |
| 65 | Fancc | 5423 | 0.276 | 0.3625 | Yes |
| 66 | Racgap1 | 5435 | 0.275 | 0.3678 | Yes |
| 67 | Rad23b | 5675 | 0.263 | 0.3646 | Yes |
| 68 | Tnpo2 | 5680 | 0.263 | 0.3699 | Yes |
| 69 | Kif15 | 5735 | 0.260 | 0.3733 | Yes |
| 70 | Tmpo | 5827 | 0.254 | 0.3752 | Yes |
| 71 | Rad54l | 5844 | 0.253 | 0.3799 | Yes |
| 72 | Srsf10 | 6045 | 0.245 | 0.3776 | Yes |
| 73 | Tacc3 | 6067 | 0.243 | 0.3819 | Yes |
| 74 | Ccna2 | 6090 | 0.242 | 0.3861 | Yes |
| 75 | Ccnt1 | 6120 | 0.242 | 0.3900 | Yes |
| 76 | Cul3 | 6124 | 0.241 | 0.3949 | Yes |
| 77 | Mki67 | 6204 | 0.238 | 0.3970 | Yes |
| 78 | Cenpe | 6295 | 0.234 | 0.3985 | Yes |
| 79 | Odf2 | 6323 | 0.233 | 0.4023 | Yes |
| 80 | Hira | 6826 | 0.222 | 0.3886 | Yes |
| 81 | Hus1 | 6885 | 0.220 | 0.3910 | Yes |
| 82 | Cks2 | 6956 | 0.216 | 0.3930 | Yes |
| 83 | Ilf3 | 7048 | 0.212 | 0.3940 | Yes |
| 84 | Kif22 | 7063 | 0.211 | 0.3979 | Yes |
| 85 | Smarcc1 | 7074 | 0.211 | 0.4019 | Yes |
| 86 | Hmmr | 7079 | 0.210 | 0.4061 | Yes |
| 87 | Kif4 | 7080 | 0.210 | 0.4104 | Yes |
| 88 | Pml | 7286 | 0.202 | 0.4071 | Yes |
| 89 | Abl1 | 7310 | 0.201 | 0.4105 | Yes |
| 90 | Cdc7 | 7343 | 0.201 | 0.4135 | Yes |
| 91 | E2f1 | 7363 | 0.200 | 0.4169 | Yes |
| 92 | Kif23 | 7475 | 0.195 | 0.4169 | Yes |
| 93 | Suv39h1 | 7604 | 0.190 | 0.4161 | Yes |
| 94 | Plk4 | 7779 | 0.183 | 0.4136 | Yes |
| 95 | Wrn | 7823 | 0.181 | 0.4158 | Yes |
| 96 | Cdc25b | 7927 | 0.176 | 0.4157 | Yes |
| 97 | Fbxo5 | 7949 | 0.176 | 0.4185 | Yes |
| 98 | Map3k20 | 8019 | 0.174 | 0.4196 | Yes |
| 99 | Cul5 | 8332 | 0.161 | 0.4116 | No |
| 100 | Tpx2 | 8384 | 0.159 | 0.4130 | No |
| 101 | Brca2 | 8424 | 0.157 | 0.4148 | No |
| 102 | Mapk14 | 8461 | 0.156 | 0.4167 | No |
| 103 | Lig3 | 8837 | 0.155 | 0.4063 | No |
| 104 | Aurka | 8896 | 0.152 | 0.4073 | No |
| 105 | Traip | 8903 | 0.152 | 0.4102 | No |
| 106 | Plk1 | 8978 | 0.150 | 0.4106 | No |
| 107 | Smad3 | 9290 | 0.139 | 0.4022 | No |
| 108 | Ddx39a | 9386 | 0.136 | 0.4015 | No |
| 109 | Orc5 | 9419 | 0.135 | 0.4031 | No |
| 110 | Katna1 | 9428 | 0.134 | 0.4056 | No |
| 111 | Stag1 | 9485 | 0.133 | 0.4063 | No |
| 112 | Aurkb | 9701 | 0.126 | 0.4011 | No |
| 113 | Rasal2 | 9714 | 0.125 | 0.4032 | No |
| 114 | Cdc27 | 9717 | 0.125 | 0.4058 | No |
| 115 | Pds5b | 9768 | 0.124 | 0.4065 | No |
| 116 | Pola2 | 9862 | 0.121 | 0.4056 | No |
| 117 | Slc7a1 | 9873 | 0.121 | 0.4078 | No |
| 118 | Ttk | 9909 | 0.120 | 0.4090 | No |
| 119 | Cul4a | 9911 | 0.120 | 0.4114 | No |
| 120 | Ncl | 9975 | 0.117 | 0.4115 | No |
| 121 | Prpf4b | 10039 | 0.117 | 0.4116 | No |
| 122 | Ss18 | 10073 | 0.115 | 0.4128 | No |
| 123 | Casp8ap2 | 10268 | 0.108 | 0.4080 | No |
| 124 | Stil | 10285 | 0.108 | 0.4096 | No |
| 125 | Dtymk | 10396 | 0.104 | 0.4078 | No |
| 126 | Smc2 | 10397 | 0.104 | 0.4099 | No |
| 127 | Srsf2 | 10582 | 0.097 | 0.4052 | No |
| 128 | Slc38a1 | 10659 | 0.094 | 0.4044 | No |
| 129 | Dbf4 | 10846 | 0.089 | 0.3994 | No |
| 130 | Ccnb2 | 10982 | 0.084 | 0.3962 | No |
| 131 | Nolc1 | 11014 | 0.083 | 0.3968 | No |
| 132 | Knl1 | 11015 | 0.083 | 0.3986 | No |
| 133 | Kif20b | 11022 | 0.083 | 0.4000 | No |
| 134 | Ezh2 | 11034 | 0.082 | 0.4013 | No |
| 135 | Ctcf | 11142 | 0.078 | 0.3991 | No |
| 136 | Pafah1b1 | 11374 | 0.070 | 0.3921 | No |
| 137 | Efna5 | 11386 | 0.069 | 0.3931 | No |
| 138 | Gspt1 | 11441 | 0.068 | 0.3925 | No |
| 139 | Atrx | 11477 | 0.067 | 0.3926 | No |
| 140 | Mnat1 | 11624 | 0.062 | 0.3886 | No |
| 141 | Ythdc1 | 11847 | 0.055 | 0.3816 | No |
| 142 | Mtf2 | 11890 | 0.054 | 0.3812 | No |
| 143 | Smc4 | 12161 | 0.044 | 0.3723 | No |
| 144 | Notch2 | 12169 | 0.044 | 0.3729 | No |
| 145 | H2az1 | 12268 | 0.040 | 0.3702 | No |
| 146 | Arid4a | 12850 | 0.021 | 0.3494 | No |
| 147 | Hif1a | 13015 | 0.016 | 0.3438 | No |
| 148 | Hmgb3 | 13124 | 0.014 | 0.3401 | No |
| 149 | Prmt5 | 13255 | 0.010 | 0.3356 | No |
| 150 | Gins2 | 13356 | 0.007 | 0.3321 | No |
| 151 | Orc6 | 14529 | -0.013 | 0.2896 | No |
| 152 | Pbk | 14736 | -0.019 | 0.2825 | No |
| 153 | Kif5b | 14916 | -0.027 | 0.2765 | No |
| 154 | Chmp1a | 15263 | -0.039 | 0.2647 | No |
| 155 | Ndc80 | 15365 | -0.043 | 0.2619 | No |
| 156 | Slc7a5 | 15379 | -0.043 | 0.2623 | No |
| 157 | E2f4 | 15447 | -0.045 | 0.2608 | No |
| 158 | Marcks | 15827 | -0.057 | 0.2481 | No |
| 159 | Mad2l1 | 16000 | -0.062 | 0.2431 | No |
| 160 | Bub3 | 16188 | -0.067 | 0.2377 | No |
| 161 | Rpa2 | 16428 | -0.073 | 0.2305 | No |
| 162 | Jpt1 | 16433 | -0.074 | 0.2319 | No |
| 163 | Cbx1 | 16800 | -0.086 | 0.2203 | No |
| 164 | Cdkn1b | 16875 | -0.089 | 0.2195 | No |
| 165 | Top1 | 17041 | -0.095 | 0.2154 | No |
| 166 | Tle3 | 17131 | -0.098 | 0.2142 | No |
| 167 | Nusap1 | 17538 | -0.113 | 0.2017 | No |
| 168 | Stmn1 | 18113 | -0.129 | 0.1834 | No |
| 169 | Foxn3 | 18137 | -0.130 | 0.1853 | No |
| 170 | Dkc1 | 18227 | -0.133 | 0.1848 | No |
| 171 | Pttg1 | 18836 | -0.155 | 0.1658 | No |
| 172 | Troap | 19193 | -0.169 | 0.1563 | No |
| 173 | Cenpa | 19741 | -0.192 | 0.1404 | No |
| 174 | Snrpd1 | 19749 | -0.192 | 0.1441 | No |
| 175 | Sap30 | 20324 | -0.211 | 0.1275 | No |
| 176 | Rps6ka5 | 21066 | -0.234 | 0.1053 | No |
| 177 | Bcl3 | 21068 | -0.234 | 0.1101 | No |
| 178 | Cdc20 | 21269 | -0.242 | 0.1078 | No |
| 179 | Cks1b | 21363 | -0.246 | 0.1095 | No |
| 180 | Birc5 | 21427 | -0.249 | 0.1123 | No |
| 181 | Ube2c | 21455 | -0.250 | 0.1165 | No |
| 182 | H2ax | 21809 | -0.260 | 0.1090 | No |
| 183 | Dmd | 21869 | -0.263 | 0.1123 | No |
| 184 | Meis2 | 21990 | -0.269 | 0.1135 | No |
| 185 | Kmt5a | 22213 | -0.279 | 0.1112 | No |
| 186 | Myc | 22627 | -0.295 | 0.1022 | No |
| 187 | Cdk4 | 23242 | -0.320 | 0.0864 | No |
| 188 | Meis1 | 24990 | -0.413 | 0.0312 | No |
| 189 | H2az2 | 25248 | -0.428 | 0.0307 | No |
| 190 | Cdkn3 | 25332 | -0.433 | 0.0366 | No |
| 191 | Pura | 25812 | -0.468 | 0.0288 | No |
| 192 | Tgfb1 | 25986 | -0.486 | 0.0326 | No |
| 193 | Atf5 | 26327 | -0.518 | 0.0309 | No |
| 194 | Hmga1b | 27380 | -0.753 | 0.0081 | No |

