| Dataset | MEP.MEP.ery_Pheno.cls #Group1_versus_Group4.MEP.ery_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | MEP.ery_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.38834897 |
| Normalized Enrichment Score (NES) | 1.1891139 |
| Nominal p-value | 0.3468208 |
| FDR q-value | 0.73570716 |
| FWER p-Value | 0.96 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ipo7 | 404 | 0.728 | 0.0002 | Yes |
| 2 | Dck | 629 | 0.658 | 0.0056 | Yes |
| 3 | Bard1 | 838 | 0.607 | 0.0105 | Yes |
| 4 | Hnrnpd | 840 | 0.607 | 0.0230 | Yes |
| 5 | Xpo1 | 907 | 0.592 | 0.0328 | Yes |
| 6 | Rad21 | 960 | 0.585 | 0.0429 | Yes |
| 7 | Timeless | 1181 | 0.550 | 0.0462 | Yes |
| 8 | Mcm5 | 1189 | 0.549 | 0.0573 | Yes |
| 9 | Mcm2 | 1268 | 0.539 | 0.0655 | Yes |
| 10 | Ccp110 | 1374 | 0.526 | 0.0725 | Yes |
| 11 | Espl1 | 1490 | 0.512 | 0.0789 | Yes |
| 12 | Wdr90 | 1535 | 0.508 | 0.0877 | Yes |
| 13 | Cse1l | 1624 | 0.499 | 0.0948 | Yes |
| 14 | Lmnb1 | 1698 | 0.491 | 0.1022 | Yes |
| 15 | Melk | 1887 | 0.473 | 0.1051 | Yes |
| 16 | Lbr | 1925 | 0.469 | 0.1134 | Yes |
| 17 | Srsf1 | 1932 | 0.468 | 0.1228 | Yes |
| 18 | Mcm4 | 1973 | 0.465 | 0.1309 | Yes |
| 19 | Dlgap5 | 1994 | 0.463 | 0.1397 | Yes |
| 20 | Dnmt1 | 2121 | 0.451 | 0.1444 | Yes |
| 21 | Hells | 2141 | 0.449 | 0.1530 | Yes |
| 22 | Cdkn2c | 2317 | 0.434 | 0.1555 | Yes |
| 23 | Mcm3 | 2374 | 0.432 | 0.1624 | Yes |
| 24 | Ncapd2 | 2448 | 0.429 | 0.1685 | Yes |
| 25 | Mcm6 | 2450 | 0.429 | 0.1773 | Yes |
| 26 | Nup107 | 2519 | 0.425 | 0.1836 | Yes |
| 27 | Atad2 | 2785 | 0.400 | 0.1822 | Yes |
| 28 | Slbp | 2957 | 0.390 | 0.1839 | Yes |
| 29 | Mybl2 | 3047 | 0.386 | 0.1886 | Yes |
| 30 | Smc3 | 3333 | 0.372 | 0.1859 | Yes |
| 31 | Ube2s | 3540 | 0.362 | 0.1858 | Yes |
| 32 | Rpa1 | 3593 | 0.359 | 0.1913 | Yes |
| 33 | Rbbp7 | 3674 | 0.355 | 0.1957 | Yes |
| 34 | Ccne1 | 3763 | 0.350 | 0.1997 | Yes |
| 35 | Wee1 | 3815 | 0.346 | 0.2050 | Yes |
| 36 | Cdc25a | 3828 | 0.345 | 0.2117 | Yes |
| 37 | Syncrip | 3873 | 0.342 | 0.2171 | Yes |
| 38 | Prim2 | 3974 | 0.336 | 0.2204 | Yes |
| 39 | Nop56 | 4201 | 0.330 | 0.2189 | Yes |
| 40 | Kif2c | 4207 | 0.330 | 0.2255 | Yes |
| 41 | Brms1l | 4214 | 0.330 | 0.2321 | Yes |
| 42 | Zw10 | 4246 | 0.327 | 0.2377 | Yes |
| 43 | Brca1 | 4258 | 0.327 | 0.2440 | Yes |
| 44 | Top2a | 4336 | 0.322 | 0.2479 | Yes |
| 45 | Rad51c | 4342 | 0.322 | 0.2543 | Yes |
| 46 | Prps1 | 4363 | 0.321 | 0.2602 | Yes |
| 47 | Nap1l1 | 4609 | 0.312 | 0.2577 | Yes |
| 48 | Pole | 4636 | 0.311 | 0.2631 | Yes |
| 49 | Tra2b | 4650 | 0.310 | 0.2691 | Yes |
| 50 | Smc1a | 4732 | 0.305 | 0.2724 | Yes |
| 51 | Ssrp1 | 4761 | 0.304 | 0.2776 | Yes |
| 52 | Nasp | 4781 | 0.303 | 0.2832 | Yes |
| 53 | Ubr7 | 4793 | 0.303 | 0.2890 | Yes |
| 54 | Tfrc | 4906 | 0.296 | 0.2910 | Yes |
| 55 | Tk1 | 5000 | 0.292 | 0.2936 | Yes |
| 56 | Mms22l | 5148 | 0.285 | 0.2942 | Yes |
| 57 | Nup205 | 5153 | 0.285 | 0.2999 | Yes |
| 58 | Chek1 | 5213 | 0.282 | 0.3035 | Yes |
| 59 | Diaph3 | 5323 | 0.281 | 0.3053 | Yes |
| 60 | Cdk1 | 5384 | 0.278 | 0.3089 | Yes |
| 61 | Prkdc | 5411 | 0.276 | 0.3136 | Yes |
| 62 | Racgap1 | 5435 | 0.275 | 0.3184 | Yes |
| 63 | Cbx5 | 5492 | 0.271 | 0.3220 | Yes |
| 64 | Lig1 | 5504 | 0.271 | 0.3272 | Yes |
| 65 | Kif18b | 5613 | 0.265 | 0.3287 | Yes |
| 66 | Xrcc6 | 5801 | 0.256 | 0.3271 | Yes |
| 67 | Tmpo | 5827 | 0.254 | 0.3315 | Yes |
| 68 | Tacc3 | 6067 | 0.243 | 0.3277 | Yes |
| 69 | Pnn | 6094 | 0.242 | 0.3318 | Yes |
| 70 | Mki67 | 6204 | 0.238 | 0.3327 | Yes |
| 71 | Spag5 | 6252 | 0.236 | 0.3358 | Yes |
| 72 | Cenpe | 6295 | 0.234 | 0.3391 | Yes |
| 73 | Mcm7 | 6796 | 0.223 | 0.3255 | Yes |
| 74 | Hus1 | 6885 | 0.220 | 0.3268 | Yes |
| 75 | Cks2 | 6956 | 0.216 | 0.3287 | Yes |
| 76 | Eed | 7015 | 0.214 | 0.3310 | Yes |
| 77 | Ilf3 | 7048 | 0.212 | 0.3342 | Yes |
| 78 | Pcna | 7059 | 0.211 | 0.3382 | Yes |
| 79 | Kif22 | 7063 | 0.211 | 0.3424 | Yes |
| 80 | Anp32e | 7064 | 0.211 | 0.3467 | Yes |
| 81 | Hmmr | 7079 | 0.210 | 0.3506 | Yes |
| 82 | Kif4 | 7080 | 0.210 | 0.3549 | Yes |
| 83 | Tbrg4 | 7142 | 0.208 | 0.3569 | Yes |
| 84 | Bub1b | 7171 | 0.207 | 0.3602 | Yes |
| 85 | Msh2 | 7210 | 0.205 | 0.3630 | Yes |
| 86 | Cit | 7211 | 0.205 | 0.3672 | Yes |
| 87 | Pold1 | 7415 | 0.198 | 0.3639 | Yes |
| 88 | Rrm2 | 7443 | 0.196 | 0.3669 | Yes |
| 89 | Mre11a | 7479 | 0.195 | 0.3697 | Yes |
| 90 | Spc25 | 7520 | 0.193 | 0.3722 | Yes |
| 91 | Dclre1b | 7584 | 0.191 | 0.3738 | Yes |
| 92 | Suv39h1 | 7604 | 0.190 | 0.3770 | Yes |
| 93 | Depdc1a | 7751 | 0.184 | 0.3755 | Yes |
| 94 | Plk4 | 7779 | 0.183 | 0.3783 | Yes |
| 95 | Psmc3ip | 7794 | 0.182 | 0.3815 | Yes |
| 96 | Cdca8 | 7810 | 0.181 | 0.3847 | Yes |
| 97 | Cdc25b | 7927 | 0.176 | 0.3841 | Yes |
| 98 | Rfc1 | 8038 | 0.174 | 0.3837 | Yes |
| 99 | Orc2 | 8136 | 0.169 | 0.3836 | Yes |
| 100 | Tubb5 | 8144 | 0.169 | 0.3869 | Yes |
| 101 | Cnot9 | 8198 | 0.167 | 0.3883 | Yes |
| 102 | Brca2 | 8424 | 0.157 | 0.3834 | No |
| 103 | Nbn | 8847 | 0.155 | 0.3712 | No |
| 104 | Aurka | 8896 | 0.152 | 0.3725 | No |
| 105 | Plk1 | 8978 | 0.150 | 0.3727 | No |
| 106 | Ing3 | 9033 | 0.148 | 0.3738 | No |
| 107 | Cenpm | 9122 | 0.145 | 0.3735 | No |
| 108 | E2f8 | 9126 | 0.145 | 0.3764 | No |
| 109 | Nup153 | 9128 | 0.145 | 0.3793 | No |
| 110 | Ddx39a | 9386 | 0.136 | 0.3728 | No |
| 111 | Stag1 | 9485 | 0.133 | 0.3719 | No |
| 112 | Dscc1 | 9565 | 0.130 | 0.3717 | No |
| 113 | Aurkb | 9701 | 0.126 | 0.3694 | No |
| 114 | Pds5b | 9768 | 0.124 | 0.3695 | No |
| 115 | Mlh1 | 9829 | 0.123 | 0.3699 | No |
| 116 | Pola2 | 9862 | 0.121 | 0.3712 | No |
| 117 | Eif2s1 | 10297 | 0.107 | 0.3576 | No |
| 118 | Pms2 | 10327 | 0.106 | 0.3587 | No |
| 119 | Srsf2 | 10582 | 0.097 | 0.3514 | No |
| 120 | Phf5a | 10622 | 0.096 | 0.3520 | No |
| 121 | Ccnb2 | 10982 | 0.084 | 0.3406 | No |
| 122 | Nolc1 | 11014 | 0.083 | 0.3412 | No |
| 123 | Ezh2 | 11034 | 0.082 | 0.3422 | No |
| 124 | Rad51ap1 | 11035 | 0.082 | 0.3439 | No |
| 125 | Ctcf | 11142 | 0.078 | 0.3416 | No |
| 126 | Rad50 | 11209 | 0.075 | 0.3408 | No |
| 127 | Gspt1 | 11441 | 0.068 | 0.3337 | No |
| 128 | Gins3 | 11444 | 0.068 | 0.3350 | No |
| 129 | Pan2 | 11499 | 0.066 | 0.3344 | No |
| 130 | Ppp1r8 | 11754 | 0.058 | 0.3264 | No |
| 131 | Gins4 | 11931 | 0.052 | 0.3210 | No |
| 132 | Gins1 | 11999 | 0.050 | 0.3196 | No |
| 133 | Pold3 | 12043 | 0.048 | 0.3190 | No |
| 134 | Smc4 | 12161 | 0.044 | 0.3156 | No |
| 135 | Usp1 | 12259 | 0.041 | 0.3129 | No |
| 136 | H2az1 | 12268 | 0.040 | 0.3135 | No |
| 137 | Ube2t | 12298 | 0.039 | 0.3132 | No |
| 138 | Rfc3 | 12370 | 0.037 | 0.3114 | No |
| 139 | Rfc2 | 12725 | 0.025 | 0.2990 | No |
| 140 | Trip13 | 12747 | 0.024 | 0.2987 | No |
| 141 | Exosc8 | 12820 | 0.022 | 0.2966 | No |
| 142 | Psip1 | 12845 | 0.021 | 0.2961 | No |
| 143 | Donson | 12992 | 0.017 | 0.2912 | No |
| 144 | Hmgb3 | 13124 | 0.014 | 0.2867 | No |
| 145 | Ung | 14333 | -0.006 | 0.2427 | No |
| 146 | Orc6 | 14529 | -0.013 | 0.2358 | No |
| 147 | Dek | 14824 | -0.023 | 0.2256 | No |
| 148 | Asf1b | 14885 | -0.026 | 0.2239 | No |
| 149 | Tipin | 15176 | -0.036 | 0.2141 | No |
| 150 | Tcf19 | 15521 | -0.048 | 0.2025 | No |
| 151 | Chek2 | 15705 | -0.053 | 0.1969 | No |
| 152 | Ak2 | 15947 | -0.060 | 0.1894 | No |
| 153 | Mad2l1 | 16000 | -0.062 | 0.1888 | No |
| 154 | Paics | 16037 | -0.063 | 0.1887 | No |
| 155 | Smc6 | 16166 | -0.066 | 0.1854 | No |
| 156 | Pold2 | 16410 | -0.073 | 0.1781 | No |
| 157 | Rpa2 | 16428 | -0.073 | 0.1790 | No |
| 158 | Jpt1 | 16433 | -0.074 | 0.1803 | No |
| 159 | Cdkn1b | 16875 | -0.089 | 0.1661 | No |
| 160 | Ppm1d | 16901 | -0.090 | 0.1670 | No |
| 161 | Rad1 | 17065 | -0.096 | 0.1630 | No |
| 162 | Dut | 17175 | -0.100 | 0.1611 | No |
| 163 | Luc7l3 | 17700 | -0.120 | 0.1444 | No |
| 164 | Stmn1 | 18113 | -0.129 | 0.1321 | No |
| 165 | Lyar | 18304 | -0.135 | 0.1279 | No |
| 166 | Shmt1 | 18466 | -0.142 | 0.1250 | No |
| 167 | Pole4 | 18637 | -0.148 | 0.1218 | No |
| 168 | Pttg1 | 18836 | -0.155 | 0.1178 | No |
| 169 | Nudt21 | 18958 | -0.160 | 0.1167 | No |
| 170 | Mxd3 | 19045 | -0.163 | 0.1169 | No |
| 171 | Rnaseh2a | 19474 | -0.182 | 0.1050 | No |
| 172 | Cdkn2a | 19613 | -0.188 | 0.1038 | No |
| 173 | Cdca3 | 19697 | -0.190 | 0.1047 | No |
| 174 | Lsm8 | 19946 | -0.196 | 0.0997 | No |
| 175 | Hmgb2 | 20070 | -0.201 | 0.0994 | No |
| 176 | Asf1a | 20238 | -0.208 | 0.0976 | No |
| 177 | Pa2g4 | 20393 | -0.213 | 0.0963 | No |
| 178 | Spc24 | 20980 | -0.231 | 0.0797 | No |
| 179 | Cdc20 | 21269 | -0.242 | 0.0742 | No |
| 180 | Cks1b | 21363 | -0.246 | 0.0758 | No |
| 181 | Birc5 | 21427 | -0.249 | 0.0787 | No |
| 182 | Pop7 | 21646 | -0.258 | 0.0760 | No |
| 183 | H2ax | 21809 | -0.260 | 0.0755 | No |
| 184 | Snrpb | 21817 | -0.261 | 0.0806 | No |
| 185 | Ranbp1 | 22102 | -0.274 | 0.0759 | No |
| 186 | Myc | 22627 | -0.295 | 0.0628 | No |
| 187 | Prdx4 | 22700 | -0.297 | 0.0663 | No |
| 188 | Cdk4 | 23242 | -0.320 | 0.0532 | No |
| 189 | Trp53 | 23343 | -0.326 | 0.0562 | No |
| 190 | Mthfd2 | 23388 | -0.328 | 0.0614 | No |
| 191 | Tubg1 | 24174 | -0.367 | 0.0403 | No |
| 192 | Rpa3 | 24597 | -0.389 | 0.0329 | No |
| 193 | Cdkn3 | 25332 | -0.433 | 0.0150 | No |
| 194 | Ran | 26022 | -0.489 | -0.0000 | No |
| 195 | Nme1 | 26109 | -0.496 | 0.0070 | No |
| 196 | Dctpp1 | 27126 | -0.660 | -0.0164 | No |
| 197 | Hmga1b | 27380 | -0.753 | -0.0102 | No |
| 198 | Cdkn1a | 27527 | -0.885 | 0.0027 | No |

