| Dataset | MEP.MEP.ery_Pheno.cls #Group1_versus_Group4.MEP.ery_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | MEP.ery_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | -0.32739663 |
| Normalized Enrichment Score (NES) | -1.2105662 |
| Nominal p-value | 0.23791103 |
| FDR q-value | 0.48724818 |
| FWER p-Value | 0.952 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Bcat1 | 12 | 1.388 | 0.0254 | No |
| 2 | Icosl | 226 | 0.824 | 0.0330 | No |
| 3 | Mmp9 | 268 | 0.796 | 0.0463 | No |
| 4 | Prkcg | 564 | 0.674 | 0.0481 | No |
| 5 | Ccr1 | 822 | 0.610 | 0.0501 | No |
| 6 | Ccr5 | 858 | 0.604 | 0.0601 | No |
| 7 | Irf4 | 983 | 0.580 | 0.0664 | No |
| 8 | Klrd1 | 1147 | 0.557 | 0.0708 | No |
| 9 | Ache | 1295 | 0.535 | 0.0754 | No |
| 10 | Rpl3l | 1814 | 0.481 | 0.0655 | No |
| 11 | F2 | 1830 | 0.479 | 0.0739 | No |
| 12 | Akt1 | 1931 | 0.469 | 0.0790 | No |
| 13 | Il12rb1 | 1992 | 0.463 | 0.0854 | No |
| 14 | Prkcb | 2060 | 0.458 | 0.0915 | No |
| 15 | Egfr | 2118 | 0.451 | 0.0979 | No |
| 16 | Il1b | 2222 | 0.438 | 0.1023 | No |
| 17 | Traf2 | 2800 | 0.398 | 0.0886 | No |
| 18 | Ube2n | 2876 | 0.396 | 0.0933 | No |
| 19 | Gzmb | 3312 | 0.374 | 0.0844 | No |
| 20 | Cd247 | 3686 | 0.355 | 0.0774 | No |
| 21 | Abce1 | 3813 | 0.347 | 0.0793 | No |
| 22 | Ncr1 | 3831 | 0.345 | 0.0851 | No |
| 23 | Brca1 | 4258 | 0.327 | 0.0756 | No |
| 24 | Timp1 | 4627 | 0.312 | 0.0680 | No |
| 25 | Thy1 | 4674 | 0.309 | 0.0721 | No |
| 26 | Jak2 | 4712 | 0.307 | 0.0765 | No |
| 27 | Ly75 | 4727 | 0.306 | 0.0817 | No |
| 28 | Il4ra | 4850 | 0.300 | 0.0828 | No |
| 29 | Eif3a | 5009 | 0.292 | 0.0825 | No |
| 30 | Nlrp3 | 5806 | 0.256 | 0.0582 | No |
| 31 | Nos2 | 5981 | 0.247 | 0.0565 | No |
| 32 | Cd74 | 6142 | 0.241 | 0.0551 | No |
| 33 | Cd3d | 6410 | 0.229 | 0.0497 | No |
| 34 | Fasl | 6630 | 0.225 | 0.0459 | No |
| 35 | Tlr1 | 6801 | 0.223 | 0.0438 | No |
| 36 | Mrpl3 | 6981 | 0.215 | 0.0413 | No |
| 37 | Map3k7 | 7041 | 0.212 | 0.0431 | No |
| 38 | Il18 | 7501 | 0.194 | 0.0300 | No |
| 39 | Wars1 | 7523 | 0.193 | 0.0328 | No |
| 40 | Cd4 | 7747 | 0.184 | 0.0281 | No |
| 41 | Gcnt1 | 7832 | 0.181 | 0.0284 | No |
| 42 | Igsf6 | 8327 | 0.161 | 0.0134 | No |
| 43 | Eif4g3 | 8447 | 0.157 | 0.0120 | No |
| 44 | Inhba | 8542 | 0.155 | 0.0115 | No |
| 45 | Hcls1 | 8907 | 0.152 | 0.0011 | No |
| 46 | Nck1 | 9026 | 0.149 | -0.0005 | No |
| 47 | Cfp | 9082 | 0.146 | 0.0002 | No |
| 48 | Galnt1 | 9373 | 0.137 | -0.0078 | No |
| 49 | Lif | 9494 | 0.132 | -0.0097 | No |
| 50 | H2-DMb2 | 9671 | 0.127 | -0.0138 | No |
| 51 | Cd86 | 9814 | 0.123 | -0.0166 | No |
| 52 | Abi1 | 9856 | 0.122 | -0.0159 | No |
| 53 | Ccl5 | 10079 | 0.115 | -0.0218 | No |
| 54 | Cd40lg | 10424 | 0.103 | -0.0325 | No |
| 55 | Tapbp | 11464 | 0.067 | -0.0691 | No |
| 56 | Gpr65 | 11577 | 0.063 | -0.0720 | No |
| 57 | Irf8 | 12238 | 0.041 | -0.0953 | No |
| 58 | Tlr3 | 12728 | 0.025 | -0.1126 | No |
| 59 | Flna | 12784 | 0.023 | -0.1142 | No |
| 60 | Hif1a | 13015 | 0.016 | -0.1223 | No |
| 61 | Ereg | 13824 | 0.000 | -0.1517 | No |
| 62 | Cd3e | 13834 | 0.000 | -0.1520 | No |
| 63 | Eif3j1 | 14546 | -0.013 | -0.1777 | No |
| 64 | Tpd52 | 14679 | -0.017 | -0.1822 | No |
| 65 | Ripk2 | 14762 | -0.020 | -0.1848 | No |
| 66 | Tap2 | 14857 | -0.025 | -0.1878 | No |
| 67 | H2-Ob | 14954 | -0.028 | -0.1908 | No |
| 68 | Il2rb | 15066 | -0.032 | -0.1942 | No |
| 69 | Il11 | 15831 | -0.057 | -0.2210 | No |
| 70 | Cd80 | 15903 | -0.059 | -0.2225 | No |
| 71 | Ccr2 | 15963 | -0.061 | -0.2235 | No |
| 72 | Il18rap | 16105 | -0.064 | -0.2275 | No |
| 73 | Cd2 | 16331 | -0.071 | -0.2343 | No |
| 74 | Glmn | 17107 | -0.098 | -0.2608 | No |
| 75 | Eif3d | 17142 | -0.099 | -0.2602 | No |
| 76 | Ltb | 17294 | -0.104 | -0.2637 | No |
| 77 | Socs5 | 17436 | -0.110 | -0.2668 | No |
| 78 | Hdac9 | 17665 | -0.118 | -0.2729 | No |
| 79 | Was | 17670 | -0.118 | -0.2709 | No |
| 80 | Stat1 | 17701 | -0.120 | -0.2697 | No |
| 81 | Csk | 17733 | -0.121 | -0.2686 | No |
| 82 | Itk | 17778 | -0.122 | -0.2679 | No |
| 83 | Dyrk3 | 18225 | -0.133 | -0.2817 | No |
| 84 | Ly86 | 18361 | -0.138 | -0.2841 | No |
| 85 | Degs1 | 18549 | -0.145 | -0.2882 | No |
| 86 | Tlr2 | 18629 | -0.148 | -0.2883 | No |
| 87 | Crtam | 18690 | -0.150 | -0.2877 | No |
| 88 | F2r | 18815 | -0.155 | -0.2893 | No |
| 89 | Ptpn6 | 18918 | -0.158 | -0.2901 | No |
| 90 | Cd47 | 19077 | -0.164 | -0.2928 | No |
| 91 | Apbb1 | 19228 | -0.171 | -0.2951 | No |
| 92 | Il27ra | 19253 | -0.172 | -0.2928 | No |
| 93 | Ets1 | 19274 | -0.173 | -0.2903 | No |
| 94 | Il12a | 19322 | -0.175 | -0.2887 | No |
| 95 | Cdkn2a | 19613 | -0.188 | -0.2958 | No |
| 96 | Il7 | 19770 | -0.193 | -0.2979 | No |
| 97 | Map4k1 | 19783 | -0.193 | -0.2947 | No |
| 98 | Fgr | 20120 | -0.203 | -0.3032 | No |
| 99 | Cd96 | 20229 | -0.208 | -0.3032 | No |
| 100 | Il10 | 20270 | -0.209 | -0.3008 | No |
| 101 | Tap1 | 20823 | -0.223 | -0.3168 | No |
| 102 | Fcgr2b | 20941 | -0.229 | -0.3168 | No |
| 103 | Bcl3 | 21068 | -0.234 | -0.3170 | No |
| 104 | Stab1 | 21099 | -0.235 | -0.3137 | No |
| 105 | Ikbkb | 21242 | -0.240 | -0.3144 | No |
| 106 | Acvr2a | 21469 | -0.250 | -0.3180 | No |
| 107 | Lck | 21535 | -0.253 | -0.3156 | No |
| 108 | Icam1 | 21859 | -0.263 | -0.3225 | Yes |
| 109 | Il2 | 21994 | -0.269 | -0.3224 | Yes |
| 110 | Irf7 | 22108 | -0.274 | -0.3214 | Yes |
| 111 | Il15 | 22116 | -0.274 | -0.3165 | Yes |
| 112 | Cd1d2 | 22133 | -0.275 | -0.3120 | Yes |
| 113 | Trat1 | 22220 | -0.279 | -0.3099 | Yes |
| 114 | Mtif2 | 22380 | -0.285 | -0.3104 | Yes |
| 115 | Cd79a | 22736 | -0.298 | -0.3178 | Yes |
| 116 | Ptprc | 22823 | -0.302 | -0.3153 | Yes |
| 117 | Bcl10 | 22968 | -0.310 | -0.3148 | Yes |
| 118 | Itgal | 23138 | -0.315 | -0.3151 | Yes |
| 119 | Cd28 | 23220 | -0.319 | -0.3121 | Yes |
| 120 | Npm1 | 23251 | -0.321 | -0.3072 | Yes |
| 121 | Tlr6 | 23385 | -0.327 | -0.3060 | Yes |
| 122 | Lcp2 | 23635 | -0.340 | -0.3087 | Yes |
| 123 | Tnf | 23851 | -0.352 | -0.3100 | Yes |
| 124 | Cd40 | 23951 | -0.357 | -0.3069 | Yes |
| 125 | Ctss | 23959 | -0.357 | -0.3005 | Yes |
| 126 | Itgb2 | 24015 | -0.360 | -0.2958 | Yes |
| 127 | Zap70 | 24164 | -0.367 | -0.2944 | Yes |
| 128 | Cd3g | 24336 | -0.375 | -0.2936 | Yes |
| 129 | Cd7 | 24366 | -0.375 | -0.2877 | Yes |
| 130 | H2-DMa | 24577 | -0.388 | -0.2881 | Yes |
| 131 | Prf1 | 24738 | -0.399 | -0.2865 | Yes |
| 132 | Ifngr2 | 24824 | -0.405 | -0.2821 | Yes |
| 133 | Ifngr1 | 25024 | -0.414 | -0.2816 | Yes |
| 134 | Il16 | 25312 | -0.431 | -0.2841 | Yes |
| 135 | Tgfb2 | 25318 | -0.432 | -0.2762 | Yes |
| 136 | Il4 | 25329 | -0.432 | -0.2685 | Yes |
| 137 | St8sia4 | 25348 | -0.434 | -0.2611 | Yes |
| 138 | Rpl9 | 25421 | -0.439 | -0.2555 | Yes |
| 139 | Rpl39-ps | 25533 | -0.446 | -0.2512 | Yes |
| 140 | H2-Aa | 25609 | -0.451 | -0.2456 | Yes |
| 141 | Ncf4 | 25858 | -0.473 | -0.2458 | Yes |
| 142 | Lyn | 25918 | -0.480 | -0.2390 | Yes |
| 143 | Ifnar2 | 25938 | -0.482 | -0.2307 | Yes |
| 144 | Tgfb1 | 25986 | -0.486 | -0.2234 | Yes |
| 145 | Nme1 | 26109 | -0.496 | -0.2186 | Yes |
| 146 | Ube2d1 | 26127 | -0.498 | -0.2100 | Yes |
| 147 | H2-Oa | 26286 | -0.514 | -0.2062 | Yes |
| 148 | Stat4 | 26340 | -0.518 | -0.1984 | Yes |
| 149 | Elane | 26349 | -0.520 | -0.1890 | Yes |
| 150 | Elf4 | 26515 | -0.540 | -0.1850 | Yes |
| 151 | Capg | 26530 | -0.542 | -0.1754 | Yes |
| 152 | Rps3a1 | 26531 | -0.542 | -0.1653 | Yes |
| 153 | Eif5a | 26599 | -0.551 | -0.1575 | Yes |
| 154 | Il2ra | 26629 | -0.556 | -0.1482 | Yes |
| 155 | Psmb10 | 26706 | -0.569 | -0.1404 | Yes |
| 156 | Socs1 | 26766 | -0.578 | -0.1318 | Yes |
| 157 | Ccnd2 | 26874 | -0.597 | -0.1246 | Yes |
| 158 | Il6 | 26888 | -0.600 | -0.1138 | Yes |
| 159 | Pf4 | 26926 | -0.609 | -0.1039 | Yes |
| 160 | Rps9 | 26982 | -0.624 | -0.0942 | Yes |
| 161 | Ccnd3 | 27146 | -0.663 | -0.0878 | Yes |
| 162 | C2 | 27186 | -0.671 | -0.0767 | Yes |
| 163 | Fas | 27259 | -0.696 | -0.0664 | Yes |
| 164 | Il2rg | 27400 | -0.765 | -0.0573 | Yes |
| 165 | Spi1 | 27489 | -0.838 | -0.0449 | Yes |
| 166 | Csf1 | 27498 | -0.847 | -0.0294 | Yes |
| 167 | Srgn | 27507 | -0.862 | -0.0136 | Yes |
| 168 | B2m | 27547 | -0.915 | 0.0020 | Yes |

