Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	MEP.MEP.ery_Pheno.cls #Group1_versus_Group3.MEP.ery_Pheno.cls #Group1_versus_Group3_repos
Phenotype	MEP.ery_Pheno.cls#Group1_versus_Group3_repos
Upregulated in class	2
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.2649839
Normalized Enrichment Score (NES)	-1.1896765
Nominal p-value	0.27290836
FDR q-value	0.53491026
FWER p-Value	0.941

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Camk4	575	0.570	0.0059	No
2	Fgf17	1498	0.432	-0.0073	No
3	Cltc	1588	0.426	0.0095	No
4	Cdk2	1792	0.404	0.0211	No
5	Nod1	2285	0.367	0.0205	No
6	Cab39	3568	0.292	-0.0124	No
7	Ptpn11	3646	0.288	-0.0017	No
8	Ube2n	4799	0.237	-0.0324	No
9	Ngf	4977	0.229	-0.0280	No
10	Cdk1	5146	0.226	-0.0235	No
11	Tbk1	5273	0.222	-0.0176	No
12	Map3k7	5431	0.215	-0.0132	No
13	E2f1	5689	0.207	-0.0128	No
14	Adcy2	5924	0.198	-0.0120	No
15	Pikfyve	5938	0.197	-0.0032	No
16	Egfr	5985	0.195	0.0043	No
17	Plcb1	5994	0.195	0.0132	No
18	Raf1	6294	0.183	0.0109	No
19	Lck	6387	0.180	0.0160	No
20	Traf2	6455	0.178	0.0220	No
21	Prkaa2	6636	0.172	0.0235	No
22	Mknk1	7059	0.157	0.0156	No
23	Cdkn1b	7552	0.148	0.0046	No
24	Ppp2r1b	7711	0.143	0.0056	No
25	Mapk9	7723	0.142	0.0119	No
26	Rptor	7764	0.141	0.0170	No
27	Mapk8	7848	0.138	0.0205	No
28	Mapk1	8111	0.131	0.0172	No
29	Atf1	8195	0.129	0.0202	No
30	Grk2	8660	0.114	0.0087	No
31	Nck1	8690	0.113	0.0130	No
32	Pla2g12a	9167	0.100	0.0003	No
33	Actr3	9272	0.097	0.0011	No
34	Il4	9392	0.093	0.0011	No
35	Pak4	9466	0.091	0.0027	No
36	Plcg1	9534	0.088	0.0045	No
37	Mknk2	9618	0.086	0.0055	No
38	Arf1	9694	0.083	0.0067	No
39	Gsk3b	9865	0.079	0.0042	No
40	Prkag1	10031	0.075	0.0017	No
41	Pik3r3	10178	0.070	-0.0003	No
42	Hsp90b1	10476	0.061	-0.0082	No
43	Akt1	10736	0.054	-0.0151	No
44	Arpc3	10806	0.052	-0.0152	No
45	Tsc2	11145	0.042	-0.0255	No
46	Rps6ka1	11428	0.034	-0.0341	No
47	Actr2	11649	0.029	-0.0408	No
48	Ripk1	11693	0.028	-0.0411	No
49	Pdk1	12006	0.021	-0.0515	No
50	Tiam1	12035	0.020	-0.0515	No
51	Prkar2a	12156	0.017	-0.0551	No
52	Eif4e	12264	0.013	-0.0584	No
53	Mapkap1	12360	0.010	-0.0613	No
54	Fgf22	12717	0.001	-0.0742	No
55	Smad2	13142	-0.000	-0.0896	No
56	Cab39l	13512	-0.010	-0.1026	No
57	Ube2d3	14041	-0.025	-0.1206	No
58	Ddit3	14777	-0.046	-0.1451	No
59	Pten	15009	-0.053	-0.1511	No
60	Ap2m1	15032	-0.054	-0.1493	No
61	Cxcr4	15179	-0.058	-0.1519	No
62	Ywhab	15335	-0.063	-0.1546	No
63	Acaca	15359	-0.064	-0.1524	No
64	Myd88	15582	-0.070	-0.1572	No
65	Mapk10	16182	-0.086	-0.1749	No
66	Calr	16227	-0.087	-0.1724	No
67	Pin1	16803	-0.105	-0.1883	No
68	Grb2	16829	-0.106	-0.1843	No
69	Arhgdia	16989	-0.111	-0.1848	No
70	Gna14	17658	-0.130	-0.2030	No
71	Sfn	17674	-0.131	-0.1974	No
72	Akt1s1	17953	-0.139	-0.2010	No
73	Fasl	18589	-0.157	-0.2167	No
74	Sqstm1	18665	-0.159	-0.2119	No
75	Rps6ka3	19173	-0.176	-0.2221	No
76	Map2k3	19348	-0.182	-0.2198	No
77	Dapp1	19906	-0.204	-0.2305	No
78	Fgf6	20280	-0.216	-0.2339	No
79	Slc2a1	21039	-0.237	-0.2503	No
80	Map2k6	21443	-0.254	-0.2530	Yes
81	Stat2	21471	-0.255	-0.2420	Yes
82	Cdk4	21496	-0.256	-0.2309	Yes
83	Rac1	21535	-0.258	-0.2201	Yes
84	Irak4	22326	-0.284	-0.2355	Yes
85	Itpr2	22875	-0.304	-0.2411	Yes
86	Vav3	22882	-0.305	-0.2270	Yes
87	Hras	23105	-0.315	-0.2202	Yes
88	Tnfrsf1a	23532	-0.336	-0.2199	Yes
89	Pfn1	23913	-0.355	-0.2170	Yes
90	Nfkbib	24265	-0.376	-0.2121	Yes
91	Sla	24320	-0.380	-0.1962	Yes
92	Ralb	24371	-0.383	-0.1800	Yes
93	Ppp1ca	24427	-0.387	-0.1638	Yes
94	Prkcb	24682	-0.398	-0.1544	Yes
95	Pitx2	25164	-0.423	-0.1520	Yes
96	Ecsit	25703	-0.464	-0.1497	Yes
97	Trib3	25830	-0.471	-0.1321	Yes
98	Dusp3	25974	-0.486	-0.1144	Yes
99	Cfl1	26051	-0.494	-0.0939	Yes
100	Il2rg	26230	-0.515	-0.0761	Yes
101	Csnk2b	26457	-0.548	-0.0586	Yes
102	Rit1	26634	-0.575	-0.0379	Yes
103	Cdkn1a	27165	-0.686	-0.0249	Yes
104	Them4	27487	-0.867	0.0042	Yes