Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	MEP.MEP.ery_Pheno.cls #Group1_versus_Group3.MEP.ery_Pheno.cls #Group1_versus_Group3_repos
Phenotype	MEP.ery_Pheno.cls#Group1_versus_Group3_repos
Upregulated in class	2
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.2811144
Normalized Enrichment Score (NES)	-1.1978819
Nominal p-value	0.21917808
FDR q-value	0.55365056
FWER p-Value	0.94

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Fos	0	1.462	0.0298	No
2	H2ac25	5	1.339	0.0570	No
3	Nudt15	287	0.680	0.0606	No
4	Clca2	395	0.629	0.0695	No
5	Jun	529	0.586	0.0766	No
6	Serpinb5	615	0.562	0.0850	No
7	Tax1bp3	838	0.519	0.0875	No
8	Cdk5r1	1251	0.460	0.0818	No
9	Ccp110	1628	0.422	0.0767	No
10	Rb1	1730	0.411	0.0814	No
11	Ppp1r15a	1842	0.399	0.0855	No
12	Jag2	1871	0.396	0.0926	No
13	Ctsf	2130	0.378	0.0909	No
14	Tchh	2506	0.354	0.0844	No
15	Polh	2636	0.343	0.0867	No
16	Hexim1	2843	0.334	0.0860	No
17	Coq8a	2980	0.325	0.0876	No
18	Rgs16	3007	0.324	0.0933	No
19	Rxra	3143	0.316	0.0948	No
20	Txnip	3410	0.300	0.0912	No
21	Cdkn2aip	3443	0.298	0.0961	No
22	Hbegf	3986	0.274	0.0819	No
23	Stom	4116	0.269	0.0827	No
24	Cd82	4233	0.263	0.0838	No
25	Pcna	4357	0.256	0.0846	No
26	Rad51c	4374	0.256	0.0892	No
27	Abcc5	4894	0.232	0.0750	No
28	Ephx1	5095	0.228	0.0724	No
29	Btg2	5156	0.225	0.0748	No
30	Slc35d1	5229	0.225	0.0768	No
31	Klf4	5295	0.221	0.0789	No
32	Lif	5463	0.214	0.0772	No
33	Fbxw7	5494	0.213	0.0804	No
34	Foxo3	5643	0.208	0.0793	No
35	Ip6k2	5771	0.204	0.0788	No
36	Mxd1	5923	0.198	0.0773	No
37	Cyfip2	5968	0.196	0.0797	No
38	Trp63	6286	0.184	0.0719	No
39	Tnfsf9	6598	0.173	0.0641	No
40	Prmt2	6700	0.170	0.0639	No
41	Aen	7083	0.156	0.0531	No
42	Rnf19b	7095	0.156	0.0559	No
43	Hdac3	7495	0.150	0.0444	No
44	Prkab1	7516	0.149	0.0467	No
45	Cgrrf1	7594	0.147	0.0469	No
46	Mdm2	7792	0.140	0.0425	No
47	Ccnd3	8048	0.133	0.0360	No
48	Hspa4l	8057	0.133	0.0384	No
49	Bmp2	8076	0.132	0.0404	No
50	Slc3a2	8099	0.131	0.0423	No
51	Vwa5a	8317	0.125	0.0369	No
52	Zbtb16	8373	0.124	0.0374	No
53	Elp1	8471	0.120	0.0363	No
54	Ak1	8932	0.106	0.0217	No
55	Ccnk	9267	0.097	0.0115	No
56	Ddb2	9288	0.096	0.0128	No
57	Kif13b	9411	0.092	0.0102	No
58	Blcap	9542	0.088	0.0072	No
59	Mknk2	9618	0.086	0.0062	No
60	Tob1	9868	0.079	-0.0012	No
61	Ddit4	9901	0.078	-0.0008	No
62	Sp1	10276	0.067	-0.0131	No
63	Wwp1	10330	0.066	-0.0137	No
64	Rchy1	10394	0.063	-0.0147	No
65	Mxd4	10501	0.061	-0.0173	No
66	Btg1	10705	0.055	-0.0236	No
67	Trafd1	10751	0.054	-0.0242	No
68	Nol8	10899	0.049	-0.0285	No
69	F2r	10975	0.047	-0.0303	No
70	Sesn1	11215	0.040	-0.0382	No
71	Sat1	11250	0.039	-0.0387	No
72	Ralgds	11531	0.031	-0.0482	No
73	Fdxr	11756	0.027	-0.0559	No
74	Rhbdf2	11900	0.023	-0.0606	No
75	Dnttip2	12049	0.019	-0.0656	No
76	Csrnp2	12054	0.019	-0.0654	No
77	Gls2	12402	0.009	-0.0778	No
78	Apaf1	12647	0.003	-0.0867	No
79	Il1a	12731	0.001	-0.0897	No
80	Abhd4	13548	-0.011	-0.1192	No
81	Tcn2	13563	-0.011	-0.1195	No
82	Iscu	13688	-0.015	-0.1237	No
83	Hmox1	13804	-0.018	-0.1276	No
84	Ier5	13924	-0.022	-0.1315	No
85	Irag2	13963	-0.023	-0.1324	No
86	Ppm1d	14023	-0.025	-0.1340	No
87	Traf4	14129	-0.028	-0.1373	No
88	Ier3	14216	-0.030	-0.1398	No
89	Klk8	14376	-0.035	-0.1449	No
90	H1f2	14424	-0.036	-0.1459	No
91	Tsc22d1	14434	-0.036	-0.1455	No
92	Pvt1	14476	-0.038	-0.1462	No
93	Ndrg1	14697	-0.044	-0.1533	No
94	Ddit3	14777	-0.046	-0.1553	No
95	Cdh13	14986	-0.052	-0.1618	No
96	Pom121	15174	-0.058	-0.1674	No
97	Wrap73	15219	-0.060	-0.1678	No
98	Zmat3	15270	-0.061	-0.1684	No
99	Upp1	15445	-0.066	-0.1734	No
100	Gadd45a	15565	-0.070	-0.1763	No
101	Fgf13	15874	-0.079	-0.1859	No
102	Abat	15882	-0.079	-0.1846	No
103	Rrad	15897	-0.079	-0.1835	No
104	Ercc5	15959	-0.081	-0.1840	No
105	Ei24	16230	-0.087	-0.1921	No
106	Itgb4	16299	-0.089	-0.1928	No
107	Rps12	16363	-0.091	-0.1932	No
108	Fam162a	16418	-0.093	-0.1933	No
109	Steap3	16627	-0.100	-0.1988	No
110	Xpc	16733	-0.103	-0.2006	No
111	Plk3	16792	-0.105	-0.2005	No
112	Rab40c	16888	-0.109	-0.2018	No
113	Tm7sf3	16925	-0.110	-0.2009	No
114	Tm4sf1	17236	-0.119	-0.2098	No
115	Tspyl2	17365	-0.120	-0.2120	No
116	Epha2	17624	-0.129	-0.2188	No
117	Sfn	17674	-0.131	-0.2179	No
118	Eps8l2	17782	-0.134	-0.2191	No
119	Sdc1	17790	-0.134	-0.2166	No
120	Ctsd	17860	-0.136	-0.2163	No
121	Rad9a	18180	-0.144	-0.2250	No
122	Tap1	18352	-0.149	-0.2282	No
123	Plk2	18536	-0.155	-0.2317	No
124	Dgka	18682	-0.160	-0.2338	No
125	Trp53	18770	-0.163	-0.2336	No
126	Pidd1	18830	-0.165	-0.2324	No
127	Sphk1	18837	-0.166	-0.2292	No
128	Ccng1	19096	-0.173	-0.2351	No
129	Pitpnc1	19414	-0.185	-0.2429	No
130	Procr	19556	-0.190	-0.2442	No
131	Zfp36l1	19627	-0.193	-0.2428	No
132	Cdkn2b	19715	-0.197	-0.2420	No
133	Bak1	19915	-0.204	-0.2451	No
134	Pmm1	20007	-0.205	-0.2442	No
135	Rap2b	20020	-0.206	-0.2404	No
136	St14	20062	-0.208	-0.2377	No
137	Atf3	20504	-0.220	-0.2493	No
138	Ankra2	20564	-0.223	-0.2469	No
139	Rrp8	21081	-0.239	-0.2609	No
140	Ada	21235	-0.245	-0.2614	No
141	Acvr1b	21348	-0.250	-0.2604	No
142	Mapkapk3	21575	-0.259	-0.2634	No
143	Fuca1	22060	-0.273	-0.2755	Yes
144	Ptpn14	22079	-0.274	-0.2705	Yes
145	Ptpre	22173	-0.279	-0.2683	Yes
146	Tgfa	22479	-0.292	-0.2734	Yes
147	Socs1	22513	-0.293	-0.2687	Yes
148	Perp	22633	-0.298	-0.2669	Yes
149	Irak1	23023	-0.312	-0.2747	Yes
150	Bax	23025	-0.313	-0.2684	Yes
151	Hras	23105	-0.315	-0.2649	Yes
152	Sec61a1	23115	-0.315	-0.2587	Yes
153	Hint1	23267	-0.323	-0.2577	Yes
154	Sertad3	23315	-0.326	-0.2527	Yes
155	Dram1	23347	-0.327	-0.2472	Yes
156	Nupr1	23453	-0.332	-0.2442	Yes
157	Slc19a2	23530	-0.336	-0.2402	Yes
158	Cd81	23861	-0.351	-0.2450	Yes
159	Baiap2	23948	-0.357	-0.2409	Yes
160	Ccnd2	24017	-0.361	-0.2360	Yes
161	Tprkb	24045	-0.362	-0.2296	Yes
162	Rpl18	24106	-0.367	-0.2243	Yes
163	Plxnb2	24133	-0.368	-0.2178	Yes
164	Retsat	24387	-0.384	-0.2192	Yes
165	Vamp8	24403	-0.385	-0.2118	Yes
166	Rpl36	24543	-0.390	-0.2090	Yes
167	App	24654	-0.396	-0.2049	Yes
168	Casp1	24681	-0.398	-0.1977	Yes
169	Alox8	24710	-0.400	-0.1906	Yes
170	Ninj1	24855	-0.409	-0.1875	Yes
171	Ifi30	24861	-0.409	-0.1793	Yes
172	H2aj	24928	-0.412	-0.1733	Yes
173	Osgin1	24931	-0.412	-0.1650	Yes
174	Notch1	25142	-0.421	-0.1641	Yes
175	Slc7a11	25263	-0.431	-0.1597	Yes
176	Tgfb1	25418	-0.440	-0.1563	Yes
177	Triap1	25475	-0.445	-0.1493	Yes
178	Vdr	25670	-0.461	-0.1470	Yes
179	Rack1	25732	-0.466	-0.1397	Yes
180	Trib3	25830	-0.471	-0.1336	Yes
181	Def6	25840	-0.473	-0.1243	Yes
182	Ldhb	26295	-0.524	-0.1301	Yes
183	Cebpa	26430	-0.543	-0.1239	Yes
184	S100a10	26491	-0.553	-0.1148	Yes
185	Tpd52l1	26539	-0.561	-0.1051	Yes
186	Phlda3	26699	-0.588	-0.0989	Yes
187	Rps27l	26795	-0.604	-0.0901	Yes
188	Cdkn2a	26810	-0.607	-0.0782	Yes
189	Gm2a	26847	-0.613	-0.0670	Yes
190	Tnni1	26851	-0.614	-0.0546	Yes
191	Fas	26888	-0.621	-0.0433	Yes
192	S100a4	27027	-0.644	-0.0352	Yes
193	Pdgfa	27088	-0.664	-0.0238	Yes
194	Dcxr	27161	-0.686	-0.0124	Yes
195	Cdkn1a	27165	-0.686	0.0014	Yes
196	Zfp365	27239	-0.709	0.0132	Yes