| Dataset | MEP.MEP.ery_Pheno.cls #Group1_versus_Group3.MEP.ery_Pheno.cls #Group1_versus_Group3_repos |
| Phenotype | MEP.ery_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_OXIDATIVE_PHOSPHORYLATION |
| Enrichment Score (ES) | -0.41244945 |
| Normalized Enrichment Score (NES) | -1.238919 |
| Nominal p-value | 0.36237624 |
| FDR q-value | 0.6280858 |
| FWER p-Value | 0.915 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Gpx4 | 1178 | 0.469 | -0.0317 | No |
| 2 | Dld | 2590 | 0.347 | -0.0748 | No |
| 3 | Hspa9 | 2637 | 0.343 | -0.0682 | No |
| 4 | Lrpprc | 3131 | 0.317 | -0.0785 | No |
| 5 | Pdha1 | 3289 | 0.307 | -0.0769 | No |
| 6 | Atp6v1h | 3362 | 0.302 | -0.0722 | No |
| 7 | Ndufs1 | 3486 | 0.295 | -0.0696 | No |
| 8 | Mgst3 | 3502 | 0.295 | -0.0630 | No |
| 9 | Afg3l2 | 3633 | 0.289 | -0.0608 | No |
| 10 | Hccs | 3680 | 0.286 | -0.0556 | No |
| 11 | Dlst | 3717 | 0.284 | -0.0501 | No |
| 12 | Sucla2 | 3831 | 0.281 | -0.0474 | No |
| 13 | Mtrr | 4420 | 0.254 | -0.0627 | No |
| 14 | Acadm | 5259 | 0.223 | -0.0879 | No |
| 15 | Oat | 5378 | 0.218 | -0.0870 | No |
| 16 | Supv3l1 | 5419 | 0.216 | -0.0833 | No |
| 17 | Pdhx | 6053 | 0.193 | -0.1017 | No |
| 18 | Ndufs3 | 6103 | 0.190 | -0.0989 | No |
| 19 | Abcb7 | 6201 | 0.187 | -0.0979 | No |
| 20 | Atp6v1c1 | 6246 | 0.185 | -0.0951 | No |
| 21 | Opa1 | 6268 | 0.184 | -0.0914 | No |
| 22 | Atp6ap1 | 6592 | 0.173 | -0.0990 | No |
| 23 | Cpt1a | 6617 | 0.172 | -0.0957 | No |
| 24 | Fdx1 | 6638 | 0.172 | -0.0923 | No |
| 25 | Cox7a2l | 7015 | 0.159 | -0.1022 | No |
| 26 | Pmpca | 7062 | 0.157 | -0.1001 | No |
| 27 | Atp6v1e1 | 7698 | 0.143 | -0.1198 | No |
| 28 | Rhot2 | 7796 | 0.140 | -0.1200 | No |
| 29 | Etfdh | 7961 | 0.135 | -0.1227 | No |
| 30 | Tomm70a | 8245 | 0.128 | -0.1299 | No |
| 31 | Mtx2 | 8258 | 0.127 | -0.1273 | No |
| 32 | Mfn2 | 8554 | 0.118 | -0.1352 | No |
| 33 | Immt | 8786 | 0.110 | -0.1410 | No |
| 34 | Mrps11 | 9743 | 0.082 | -0.1739 | No |
| 35 | Cox15 | 9821 | 0.080 | -0.1748 | No |
| 36 | Idh3a | 10029 | 0.075 | -0.1805 | No |
| 37 | Cyb5a | 10185 | 0.070 | -0.1845 | No |
| 38 | Fh1 | 10470 | 0.061 | -0.1934 | No |
| 39 | Atp6v0c | 10913 | 0.048 | -0.2083 | No |
| 40 | Ndufa9 | 10945 | 0.047 | -0.2083 | No |
| 41 | Acaa1a | 11017 | 0.045 | -0.2098 | No |
| 42 | Etfa | 11254 | 0.039 | -0.2175 | No |
| 43 | Dlat | 11564 | 0.031 | -0.2280 | No |
| 44 | Rhot1 | 11623 | 0.029 | -0.2294 | No |
| 45 | Mrps30 | 11624 | 0.029 | -0.2287 | No |
| 46 | Ogdh | 11862 | 0.024 | -0.2368 | No |
| 47 | Vdac1 | 12097 | 0.018 | -0.2449 | No |
| 48 | Hadhb | 12447 | 0.008 | -0.2574 | No |
| 49 | Cox10 | 12489 | 0.006 | -0.2588 | No |
| 50 | Got2 | 12716 | 0.001 | -0.2670 | No |
| 51 | Atp6v0e | 12721 | 0.001 | -0.2671 | No |
| 52 | Iscu | 13688 | -0.015 | -0.3019 | No |
| 53 | Glud1 | 13698 | -0.016 | -0.3019 | No |
| 54 | Ndufa5 | 13957 | -0.023 | -0.3108 | No |
| 55 | Cox11 | 13995 | -0.024 | -0.3115 | No |
| 56 | Pdhb | 14100 | -0.027 | -0.3147 | No |
| 57 | Hadha | 14325 | -0.034 | -0.3220 | No |
| 58 | Fxn | 14457 | -0.037 | -0.3259 | No |
| 59 | Maob | 14480 | -0.038 | -0.3258 | No |
| 60 | Slc25a12 | 14494 | -0.038 | -0.3254 | No |
| 61 | Sdha | 14534 | -0.039 | -0.3258 | No |
| 62 | Pdp1 | 14591 | -0.041 | -0.3269 | No |
| 63 | Aco2 | 15165 | -0.058 | -0.3464 | No |
| 64 | Ndufs4 | 15438 | -0.066 | -0.3547 | No |
| 65 | Uqcr11 | 15568 | -0.070 | -0.3578 | No |
| 66 | Mpc1 | 15615 | -0.071 | -0.3577 | No |
| 67 | Mdh2 | 15730 | -0.075 | -0.3601 | No |
| 68 | Oxa1l | 16158 | -0.086 | -0.3736 | No |
| 69 | Aifm1 | 16233 | -0.087 | -0.3742 | No |
| 70 | Nqo2 | 16288 | -0.089 | -0.3740 | No |
| 71 | Uqcrh | 16339 | -0.090 | -0.3737 | No |
| 72 | Grpel1 | 16367 | -0.091 | -0.3724 | No |
| 73 | Uqcrc1 | 16412 | -0.093 | -0.3718 | No |
| 74 | Idh1 | 16588 | -0.099 | -0.3758 | No |
| 75 | Cox17 | 16612 | -0.099 | -0.3743 | No |
| 76 | Timm8b | 16646 | -0.101 | -0.3730 | No |
| 77 | Mrpl11 | 16737 | -0.103 | -0.3738 | No |
| 78 | Cox7c | 16749 | -0.103 | -0.3717 | No |
| 79 | Htra2 | 16787 | -0.105 | -0.3706 | No |
| 80 | Prdx3 | 17080 | -0.114 | -0.3785 | No |
| 81 | Gm10053 | 17246 | -0.119 | -0.3816 | No |
| 82 | Aldh6a1 | 17482 | -0.124 | -0.3872 | No |
| 83 | Atp6v1d | 17901 | -0.138 | -0.3991 | No |
| 84 | Timm17a | 18267 | -0.147 | -0.4089 | Yes |
| 85 | Ndufb3 | 18326 | -0.149 | -0.4075 | Yes |
| 86 | Ndufb5 | 18365 | -0.150 | -0.4052 | Yes |
| 87 | Acat1 | 18436 | -0.151 | -0.4041 | Yes |
| 88 | AK157302 | 18532 | -0.155 | -0.4039 | Yes |
| 89 | Alas1 | 18584 | -0.157 | -0.4020 | Yes |
| 90 | Vdac2 | 18662 | -0.159 | -0.4009 | Yes |
| 91 | Mtrf1 | 18702 | -0.161 | -0.3985 | Yes |
| 92 | Nnt | 18706 | -0.161 | -0.3947 | Yes |
| 93 | Mdh1 | 18744 | -0.162 | -0.3922 | Yes |
| 94 | Atp1b1 | 18862 | -0.166 | -0.3924 | Yes |
| 95 | Ech1 | 18884 | -0.167 | -0.3892 | Yes |
| 96 | Suclg1 | 18935 | -0.168 | -0.3870 | Yes |
| 97 | Cox6c | 18940 | -0.168 | -0.3831 | Yes |
| 98 | Vdac3 | 19003 | -0.171 | -0.3812 | Yes |
| 99 | Acadsb | 19089 | -0.173 | -0.3801 | Yes |
| 100 | Phyh | 19127 | -0.174 | -0.3773 | Yes |
| 101 | Bckdha | 19149 | -0.175 | -0.3738 | Yes |
| 102 | Gpi1 | 19155 | -0.175 | -0.3698 | Yes |
| 103 | Ndufv2 | 19179 | -0.176 | -0.3664 | Yes |
| 104 | Ndufab1 | 19383 | -0.184 | -0.3694 | Yes |
| 105 | Cs | 19424 | -0.185 | -0.3664 | Yes |
| 106 | Idh2 | 19819 | -0.200 | -0.3759 | Yes |
| 107 | Mrpl15 | 19922 | -0.204 | -0.3747 | Yes |
| 108 | Sdhd | 19923 | -0.204 | -0.3698 | Yes |
| 109 | Ndufc1 | 20092 | -0.209 | -0.3709 | Yes |
| 110 | Ndufb6 | 20108 | -0.210 | -0.3664 | Yes |
| 111 | Surf1 | 20161 | -0.212 | -0.3632 | Yes |
| 112 | Acadvl | 20465 | -0.218 | -0.3690 | Yes |
| 113 | Ndufs6 | 20519 | -0.221 | -0.3656 | Yes |
| 114 | Casp7 | 20674 | -0.227 | -0.3657 | Yes |
| 115 | Sdhb | 20784 | -0.227 | -0.3642 | Yes |
| 116 | Cyb5r3 | 20925 | -0.233 | -0.3637 | Yes |
| 117 | Por | 21198 | -0.243 | -0.3678 | Yes |
| 118 | Mrps22 | 21270 | -0.246 | -0.3645 | Yes |
| 119 | Ndufa7 | 21364 | -0.250 | -0.3618 | Yes |
| 120 | Tcirg1 | 21547 | -0.258 | -0.3623 | Yes |
| 121 | Eci1 | 21915 | -0.267 | -0.3692 | Yes |
| 122 | Idh3g | 22021 | -0.271 | -0.3665 | Yes |
| 123 | Mrps15 | 22040 | -0.272 | -0.3606 | Yes |
| 124 | Slc25a11 | 22124 | -0.276 | -0.3570 | Yes |
| 125 | Timm9 | 22152 | -0.278 | -0.3513 | Yes |
| 126 | Cox7a2 | 22211 | -0.280 | -0.3466 | Yes |
| 127 | Echs1 | 22285 | -0.283 | -0.3425 | Yes |
| 128 | Ndufv1 | 22321 | -0.284 | -0.3369 | Yes |
| 129 | Ndufa6 | 22324 | -0.284 | -0.3301 | Yes |
| 130 | Acaa2 | 22394 | -0.288 | -0.3257 | Yes |
| 131 | Sdhc | 22442 | -0.290 | -0.3205 | Yes |
| 132 | Phb2 | 22466 | -0.291 | -0.3143 | Yes |
| 133 | Mrpl35 | 22565 | -0.295 | -0.3107 | Yes |
| 134 | Cox7b | 22605 | -0.297 | -0.3050 | Yes |
| 135 | Ndufs8 | 22791 | -0.300 | -0.3045 | Yes |
| 136 | Timm13 | 22838 | -0.303 | -0.2989 | Yes |
| 137 | Ndufs2 | 22911 | -0.307 | -0.2941 | Yes |
| 138 | Atp6v1g1 | 22925 | -0.308 | -0.2872 | Yes |
| 139 | Bax | 23025 | -0.313 | -0.2833 | Yes |
| 140 | Polr2f | 23028 | -0.313 | -0.2758 | Yes |
| 141 | Uqcrq | 23074 | -0.314 | -0.2699 | Yes |
| 142 | Ndufb7 | 23082 | -0.314 | -0.2626 | Yes |
| 143 | Ndufb2 | 23284 | -0.324 | -0.2621 | Yes |
| 144 | Ndufs7 | 23440 | -0.332 | -0.2598 | Yes |
| 145 | Slc25a3 | 23457 | -0.332 | -0.2523 | Yes |
| 146 | Uqcrc2 | 23615 | -0.338 | -0.2499 | Yes |
| 147 | Idh3b | 23760 | -0.345 | -0.2468 | Yes |
| 148 | Slc25a20 | 23821 | -0.349 | -0.2406 | Yes |
| 149 | Cox8a | 24166 | -0.371 | -0.2443 | Yes |
| 150 | Bdh2 | 24340 | -0.381 | -0.2414 | Yes |
| 151 | Retsat | 24387 | -0.384 | -0.2338 | Yes |
| 152 | Ndufa1 | 24399 | -0.385 | -0.2250 | Yes |
| 153 | Ndufa8 | 24428 | -0.387 | -0.2167 | Yes |
| 154 | Tomm22 | 24430 | -0.387 | -0.2074 | Yes |
| 155 | Mrps12 | 24497 | -0.387 | -0.2005 | Yes |
| 156 | Uqcrfs1 | 24517 | -0.388 | -0.1918 | Yes |
| 157 | Ndufa2 | 24530 | -0.389 | -0.1829 | Yes |
| 158 | Atp6v0b | 24745 | -0.403 | -0.1810 | Yes |
| 159 | Cox4i1 | 24930 | -0.412 | -0.1777 | Yes |
| 160 | Atp5pb | 24991 | -0.416 | -0.1699 | Yes |
| 161 | Decr1 | 25004 | -0.417 | -0.1603 | Yes |
| 162 | Uqcr10 | 25058 | -0.420 | -0.1521 | Yes |
| 163 | Hsd17b10 | 25226 | -0.427 | -0.1479 | Yes |
| 164 | Ndufa4 | 25252 | -0.430 | -0.1385 | Yes |
| 165 | Slc25a4 | 25370 | -0.435 | -0.1323 | Yes |
| 166 | Slc25a5 | 25566 | -0.451 | -0.1285 | Yes |
| 167 | Timm10 | 25592 | -0.453 | -0.1185 | Yes |
| 168 | Etfb | 25604 | -0.454 | -0.1080 | Yes |
| 169 | Cox5a | 25869 | -0.476 | -0.1062 | Yes |
| 170 | Cox6b1 | 25903 | -0.479 | -0.0958 | Yes |
| 171 | Cox5b | 25935 | -0.482 | -0.0853 | Yes |
| 172 | Ndufb8 | 25953 | -0.484 | -0.0743 | Yes |
| 173 | Timm50 | 25960 | -0.484 | -0.0629 | Yes |
| 174 | Ldha | 26283 | -0.523 | -0.0620 | Yes |
| 175 | Ldhb | 26295 | -0.524 | -0.0498 | Yes |
| 176 | Ndufc2 | 26394 | -0.537 | -0.0404 | Yes |
| 177 | Uqcrb | 26541 | -0.562 | -0.0322 | Yes |
| 178 | Cox6a1 | 26639 | -0.576 | -0.0219 | Yes |
| 179 | Atp6v1f | 26651 | -0.578 | -0.0084 | Yes |
| 180 | Ndufa3 | 26656 | -0.578 | 0.0054 | Yes |
| 181 | Cyc1 | 26668 | -0.580 | 0.0190 | Yes |
| 182 | Mrpl34 | 26915 | -0.624 | 0.0251 | Yes |

