| Dataset | MEP.MEP.ery_Pheno.cls #Group1_versus_Group3.MEP.ery_Pheno.cls #Group1_versus_Group3_repos |
| Phenotype | MEP.ery_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.41487822 |
| Normalized Enrichment Score (NES) | 1.7131746 |
| Nominal p-value | 0.051587302 |
| FDR q-value | 0.118712574 |
| FWER p-Value | 0.183 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Hnrnpd | 489 | 0.592 | -0.0021 | Yes |
| 2 | Cdc6 | 597 | 0.564 | 0.0091 | Yes |
| 3 | Rad21 | 903 | 0.508 | 0.0115 | Yes |
| 4 | Hnrnpu | 1150 | 0.472 | 0.0151 | Yes |
| 5 | Nasp | 1406 | 0.439 | 0.0175 | Yes |
| 6 | Lmnb1 | 1421 | 0.438 | 0.0286 | Yes |
| 7 | Nsd2 | 1432 | 0.436 | 0.0399 | Yes |
| 8 | Mcm6 | 1542 | 0.429 | 0.0473 | Yes |
| 9 | H2bc12 | 1583 | 0.427 | 0.0573 | Yes |
| 10 | Mcm2 | 1627 | 0.422 | 0.0669 | Yes |
| 11 | Lbr | 1664 | 0.419 | 0.0768 | Yes |
| 12 | Mcm5 | 1839 | 0.399 | 0.0811 | Yes |
| 13 | Mcm3 | 1870 | 0.396 | 0.0906 | Yes |
| 14 | Xpo1 | 2046 | 0.384 | 0.0944 | Yes |
| 15 | Srsf1 | 2088 | 0.380 | 0.1030 | Yes |
| 16 | E2f2 | 2259 | 0.369 | 0.1067 | Yes |
| 17 | Mybl2 | 2364 | 0.363 | 0.1125 | Yes |
| 18 | Nek2 | 2434 | 0.359 | 0.1196 | Yes |
| 19 | Chaf1a | 2449 | 0.358 | 0.1286 | Yes |
| 20 | Ythdc1 | 2632 | 0.343 | 0.1311 | Yes |
| 21 | Ube2s | 2683 | 0.339 | 0.1383 | Yes |
| 22 | Ncl | 2721 | 0.336 | 0.1459 | Yes |
| 23 | Dr1 | 2808 | 0.335 | 0.1517 | Yes |
| 24 | Tfdp1 | 2932 | 0.328 | 0.1560 | Yes |
| 25 | Kpnb1 | 2991 | 0.324 | 0.1625 | Yes |
| 26 | Kif22 | 3006 | 0.324 | 0.1706 | Yes |
| 27 | Ccna2 | 3147 | 0.316 | 0.1739 | Yes |
| 28 | Cdc25a | 3474 | 0.296 | 0.1699 | Yes |
| 29 | Numa1 | 3573 | 0.292 | 0.1741 | Yes |
| 30 | Smad3 | 3589 | 0.291 | 0.1813 | Yes |
| 31 | Smc1a | 3609 | 0.290 | 0.1884 | Yes |
| 32 | Odc1 | 3693 | 0.285 | 0.1929 | Yes |
| 33 | Aurka | 3698 | 0.285 | 0.2004 | Yes |
| 34 | Srsf10 | 3924 | 0.277 | 0.1996 | Yes |
| 35 | Sfpq | 3925 | 0.277 | 0.2069 | Yes |
| 36 | Rbl1 | 3980 | 0.274 | 0.2123 | Yes |
| 37 | Prpf4b | 4042 | 0.272 | 0.2173 | Yes |
| 38 | Bard1 | 4138 | 0.267 | 0.2209 | Yes |
| 39 | Nolc1 | 4153 | 0.266 | 0.2275 | Yes |
| 40 | Tle3 | 4176 | 0.265 | 0.2338 | Yes |
| 41 | Upf1 | 4177 | 0.265 | 0.2408 | Yes |
| 42 | Hspa8 | 4211 | 0.264 | 0.2467 | Yes |
| 43 | Hus1 | 4301 | 0.260 | 0.2503 | Yes |
| 44 | E2f3 | 4375 | 0.256 | 0.2545 | Yes |
| 45 | Cdkn2c | 4402 | 0.255 | 0.2603 | Yes |
| 46 | Tnpo2 | 4603 | 0.247 | 0.2596 | Yes |
| 47 | Bub1 | 4674 | 0.243 | 0.2635 | Yes |
| 48 | Tmpo | 4882 | 0.233 | 0.2622 | Yes |
| 49 | Abl1 | 4944 | 0.230 | 0.2661 | Yes |
| 50 | Prim2 | 5105 | 0.228 | 0.2663 | Yes |
| 51 | Hmgb3 | 5129 | 0.227 | 0.2715 | Yes |
| 52 | Cdk1 | 5146 | 0.226 | 0.2770 | Yes |
| 53 | Tra2b | 5242 | 0.224 | 0.2795 | Yes |
| 54 | Cdc45 | 5334 | 0.220 | 0.2820 | Yes |
| 55 | Pola2 | 5345 | 0.219 | 0.2875 | Yes |
| 56 | Syncrip | 5360 | 0.218 | 0.2928 | Yes |
| 57 | Fbxo5 | 5366 | 0.218 | 0.2984 | Yes |
| 58 | Wrn | 5428 | 0.216 | 0.3019 | Yes |
| 59 | Kif4 | 5442 | 0.215 | 0.3072 | Yes |
| 60 | Cul3 | 5496 | 0.213 | 0.3109 | Yes |
| 61 | G3bp1 | 5624 | 0.209 | 0.3119 | Yes |
| 62 | E2f1 | 5689 | 0.207 | 0.3150 | Yes |
| 63 | Incenp | 5766 | 0.204 | 0.3177 | Yes |
| 64 | Cul1 | 5795 | 0.203 | 0.3221 | Yes |
| 65 | Tent4a | 5817 | 0.202 | 0.3267 | Yes |
| 66 | Smarcc1 | 5832 | 0.201 | 0.3315 | Yes |
| 67 | Cks2 | 5911 | 0.198 | 0.3340 | Yes |
| 68 | Exo1 | 6001 | 0.194 | 0.3359 | Yes |
| 69 | Polq | 6173 | 0.188 | 0.3347 | Yes |
| 70 | Amd1 | 6200 | 0.187 | 0.3387 | Yes |
| 71 | Arid4a | 6250 | 0.185 | 0.3418 | Yes |
| 72 | Pml | 6313 | 0.183 | 0.3445 | Yes |
| 73 | Top2a | 6475 | 0.177 | 0.3433 | Yes |
| 74 | Stag1 | 6513 | 0.175 | 0.3466 | Yes |
| 75 | Cul4a | 6551 | 0.174 | 0.3499 | Yes |
| 76 | Cul5 | 6596 | 0.173 | 0.3529 | Yes |
| 77 | Ezh2 | 6666 | 0.171 | 0.3550 | Yes |
| 78 | Kif11 | 6774 | 0.167 | 0.3555 | Yes |
| 79 | Cenpf | 6875 | 0.164 | 0.3562 | Yes |
| 80 | Pbk | 6903 | 0.163 | 0.3596 | Yes |
| 81 | Ilf3 | 6931 | 0.162 | 0.3629 | Yes |
| 82 | Prc1 | 6987 | 0.160 | 0.3651 | Yes |
| 83 | Kif2c | 7026 | 0.159 | 0.3680 | Yes |
| 84 | Cdc7 | 7047 | 0.158 | 0.3715 | Yes |
| 85 | Chek1 | 7063 | 0.157 | 0.3751 | Yes |
| 86 | Suv39h1 | 7075 | 0.157 | 0.3789 | Yes |
| 87 | Hira | 7108 | 0.156 | 0.3819 | Yes |
| 88 | Ccnt1 | 7386 | 0.153 | 0.3758 | Yes |
| 89 | Fancc | 7520 | 0.149 | 0.3749 | Yes |
| 90 | Rad54l | 7533 | 0.148 | 0.3785 | Yes |
| 91 | Cdkn1b | 7552 | 0.148 | 0.3817 | Yes |
| 92 | Mki67 | 7658 | 0.144 | 0.3818 | Yes |
| 93 | Pole | 7692 | 0.143 | 0.3844 | Yes |
| 94 | Slc12a2 | 7903 | 0.137 | 0.3804 | Yes |
| 95 | Ewsr1 | 7944 | 0.136 | 0.3825 | Yes |
| 96 | Smc2 | 7952 | 0.135 | 0.3859 | Yes |
| 97 | Rad23b | 8045 | 0.133 | 0.3861 | Yes |
| 98 | Orc5 | 8046 | 0.133 | 0.3896 | Yes |
| 99 | Casp8ap2 | 8083 | 0.132 | 0.3918 | Yes |
| 100 | Racgap1 | 8191 | 0.129 | 0.3914 | Yes |
| 101 | Brca2 | 8211 | 0.129 | 0.3941 | Yes |
| 102 | Top1 | 8324 | 0.125 | 0.3933 | Yes |
| 103 | Sap30 | 8398 | 0.123 | 0.3940 | Yes |
| 104 | Cenpe | 8441 | 0.121 | 0.3956 | Yes |
| 105 | Uck2 | 8445 | 0.121 | 0.3988 | Yes |
| 106 | Ttk | 8453 | 0.120 | 0.4017 | Yes |
| 107 | Ddx39a | 8465 | 0.120 | 0.4045 | Yes |
| 108 | Atrx | 8483 | 0.120 | 0.4071 | Yes |
| 109 | Tacc3 | 8766 | 0.111 | 0.3997 | Yes |
| 110 | Mtf2 | 8837 | 0.109 | 0.4001 | Yes |
| 111 | Ss18 | 8877 | 0.108 | 0.4016 | Yes |
| 112 | Nup98 | 8908 | 0.107 | 0.4033 | Yes |
| 113 | Cdc27 | 8909 | 0.107 | 0.4062 | Yes |
| 114 | Plk4 | 8977 | 0.105 | 0.4065 | Yes |
| 115 | E2f4 | 8996 | 0.104 | 0.4086 | Yes |
| 116 | Odf2 | 9026 | 0.103 | 0.4103 | Yes |
| 117 | Pafah1b1 | 9036 | 0.103 | 0.4127 | Yes |
| 118 | Efna5 | 9053 | 0.102 | 0.4149 | Yes |
| 119 | Pds5b | 9192 | 0.099 | 0.4125 | No |
| 120 | Espl1 | 9269 | 0.097 | 0.4123 | No |
| 121 | Gspt1 | 9274 | 0.097 | 0.4147 | No |
| 122 | Nup50 | 9785 | 0.081 | 0.3983 | No |
| 123 | Kif5b | 9875 | 0.079 | 0.3971 | No |
| 124 | Lig3 | 9934 | 0.077 | 0.3971 | No |
| 125 | Tpx2 | 10072 | 0.073 | 0.3940 | No |
| 126 | Ccnf | 10085 | 0.073 | 0.3955 | No |
| 127 | Kif15 | 10096 | 0.073 | 0.3971 | No |
| 128 | Map3k20 | 10264 | 0.068 | 0.3928 | No |
| 129 | Dtymk | 10317 | 0.066 | 0.3927 | No |
| 130 | Ctcf | 10475 | 0.061 | 0.3886 | No |
| 131 | Hmmr | 10558 | 0.059 | 0.3872 | No |
| 132 | Notch2 | 10600 | 0.058 | 0.3872 | No |
| 133 | Prmt5 | 10728 | 0.054 | 0.3840 | No |
| 134 | Rpa2 | 10812 | 0.052 | 0.3824 | No |
| 135 | Kif23 | 10967 | 0.047 | 0.3780 | No |
| 136 | Katna1 | 10989 | 0.046 | 0.3785 | No |
| 137 | Mapk14 | 11296 | 0.037 | 0.3683 | No |
| 138 | Mad2l1 | 11417 | 0.034 | 0.3648 | No |
| 139 | Smc4 | 11514 | 0.032 | 0.3622 | No |
| 140 | Ndc80 | 12278 | 0.013 | 0.3347 | No |
| 141 | Rasal2 | 12398 | 0.009 | 0.3306 | No |
| 142 | Stil | 12494 | 0.006 | 0.3273 | No |
| 143 | Gins2 | 12539 | 0.005 | 0.3258 | No |
| 144 | Mnat1 | 12650 | 0.003 | 0.3219 | No |
| 145 | Srsf2 | 13242 | -0.003 | 0.3004 | No |
| 146 | Foxn3 | 13351 | -0.005 | 0.2966 | No |
| 147 | Dkc1 | 13415 | -0.007 | 0.2945 | No |
| 148 | Traip | 13526 | -0.010 | 0.2907 | No |
| 149 | Slc38a1 | 13761 | -0.017 | 0.2827 | No |
| 150 | Rps6ka5 | 13842 | -0.020 | 0.2803 | No |
| 151 | Knl1 | 13875 | -0.021 | 0.2797 | No |
| 152 | Kif20b | 13987 | -0.024 | 0.2762 | No |
| 153 | Aurkb | 13991 | -0.024 | 0.2768 | No |
| 154 | Orc6 | 14116 | -0.027 | 0.2730 | No |
| 155 | Slc7a1 | 14214 | -0.030 | 0.2702 | No |
| 156 | Sqle | 14237 | -0.031 | 0.2703 | No |
| 157 | Hif1a | 14453 | -0.037 | 0.2634 | No |
| 158 | Dbf4 | 14470 | -0.037 | 0.2638 | No |
| 159 | Plk1 | 14604 | -0.041 | 0.2601 | No |
| 160 | Egf | 15177 | -0.058 | 0.2407 | No |
| 161 | Kmt5a | 15208 | -0.059 | 0.2412 | No |
| 162 | Cbx1 | 16046 | -0.083 | 0.2129 | No |
| 163 | Chmp1a | 16448 | -0.094 | 0.2008 | No |
| 164 | Ccnb2 | 16518 | -0.096 | 0.2008 | No |
| 165 | H2az1 | 16713 | -0.103 | 0.1965 | No |
| 166 | Bcl3 | 16950 | -0.110 | 0.1908 | No |
| 167 | Snrpd1 | 17353 | -0.120 | 0.1793 | No |
| 168 | Marcks | 17388 | -0.121 | 0.1813 | No |
| 169 | Myc | 17389 | -0.121 | 0.1845 | No |
| 170 | Atf5 | 17736 | -0.133 | 0.1755 | No |
| 171 | Meis1 | 17863 | -0.136 | 0.1745 | No |
| 172 | Nusap1 | 18119 | -0.142 | 0.1690 | No |
| 173 | Stmn1 | 18283 | -0.147 | 0.1669 | No |
| 174 | Pura | 18334 | -0.149 | 0.1691 | No |
| 175 | Bub3 | 19317 | -0.181 | 0.1381 | No |
| 176 | Cks1b | 19699 | -0.196 | 0.1294 | No |
| 177 | Cdc25b | 19837 | -0.201 | 0.1298 | No |
| 178 | Ccnd1 | 20203 | -0.213 | 0.1221 | No |
| 179 | H2ax | 20884 | -0.232 | 0.1035 | No |
| 180 | Meis2 | 21077 | -0.239 | 0.1028 | No |
| 181 | Birc5 | 21389 | -0.251 | 0.0982 | No |
| 182 | Cdk4 | 21496 | -0.256 | 0.1011 | No |
| 183 | Slc7a5 | 21912 | -0.267 | 0.0931 | No |
| 184 | Jpt1 | 21945 | -0.269 | 0.0991 | No |
| 185 | Cdc20 | 22524 | -0.293 | 0.0858 | No |
| 186 | H2az2 | 22886 | -0.305 | 0.0808 | No |
| 187 | Troap | 22944 | -0.309 | 0.0870 | No |
| 188 | Cenpa | 23107 | -0.315 | 0.0894 | No |
| 189 | Pttg1 | 23140 | -0.317 | 0.0967 | No |
| 190 | Dmd | 23483 | -0.333 | 0.0931 | No |
| 191 | Ube2c | 23729 | -0.344 | 0.0934 | No |
| 192 | Tgfb1 | 25418 | -0.440 | 0.0435 | No |
| 193 | Hmga1b | 26935 | -0.626 | 0.0049 | No |
| 194 | Cdkn3 | 27292 | -0.729 | 0.0113 | No |

