| Dataset | MEP.MEP.ery_Pheno.cls #Group1_versus_Group3.MEP.ery_Pheno.cls #Group1_versus_Group3_repos |
| Phenotype | MEP.ery_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | -0.38563356 |
| Normalized Enrichment Score (NES) | -1.3503791 |
| Nominal p-value | 0.13412228 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.772 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Rpl3l | 199 | 0.739 | 0.0092 | No |
| 2 | Cd40lg | 513 | 0.588 | 0.0108 | No |
| 3 | Nlrp3 | 963 | 0.500 | 0.0056 | No |
| 4 | Fgr | 1380 | 0.443 | 0.0003 | No |
| 5 | Mmp9 | 1390 | 0.441 | 0.0097 | No |
| 6 | Apbb1 | 2065 | 0.381 | -0.0063 | No |
| 7 | Il2rb | 2203 | 0.373 | -0.0031 | No |
| 8 | Tlr3 | 2222 | 0.371 | 0.0045 | No |
| 9 | Ache | 2322 | 0.364 | 0.0090 | No |
| 10 | Irf7 | 2835 | 0.334 | -0.0022 | No |
| 11 | Prf1 | 2960 | 0.326 | 0.0005 | No |
| 12 | Fcgr2b | 3181 | 0.313 | -0.0006 | No |
| 13 | Eif3a | 3373 | 0.302 | -0.0008 | No |
| 14 | Brca1 | 3900 | 0.278 | -0.0138 | No |
| 15 | Thy1 | 4225 | 0.263 | -0.0198 | No |
| 16 | Nos2 | 4288 | 0.260 | -0.0162 | No |
| 17 | F2 | 4325 | 0.258 | -0.0118 | No |
| 18 | Ube2n | 4799 | 0.237 | -0.0238 | No |
| 19 | Jak2 | 4867 | 0.234 | -0.0210 | No |
| 20 | Mrpl3 | 5283 | 0.222 | -0.0312 | No |
| 21 | Map3k7 | 5431 | 0.215 | -0.0318 | No |
| 22 | Lif | 5463 | 0.214 | -0.0281 | No |
| 23 | Il2ra | 5703 | 0.206 | -0.0323 | No |
| 24 | Egfr | 5985 | 0.195 | -0.0382 | No |
| 25 | Cd4 | 6008 | 0.194 | -0.0347 | No |
| 26 | Lck | 6387 | 0.180 | -0.0444 | No |
| 27 | Traf2 | 6455 | 0.178 | -0.0429 | No |
| 28 | Timp1 | 6575 | 0.174 | -0.0434 | No |
| 29 | Tgfb2 | 6689 | 0.170 | -0.0437 | No |
| 30 | Prkcg | 6701 | 0.170 | -0.0403 | No |
| 31 | Stat1 | 7046 | 0.158 | -0.0494 | No |
| 32 | Eif4g3 | 7349 | 0.154 | -0.0570 | No |
| 33 | Abce1 | 7384 | 0.153 | -0.0548 | No |
| 34 | Gcnt1 | 7870 | 0.138 | -0.0694 | No |
| 35 | Ccnd3 | 8048 | 0.133 | -0.0729 | No |
| 36 | Dyrk3 | 8310 | 0.126 | -0.0796 | No |
| 37 | Hcls1 | 8372 | 0.124 | -0.0791 | No |
| 38 | Abi1 | 8504 | 0.119 | -0.0812 | No |
| 39 | Nck1 | 8690 | 0.113 | -0.0854 | No |
| 40 | Cd247 | 8969 | 0.105 | -0.0932 | No |
| 41 | Tlr6 | 8976 | 0.105 | -0.0911 | No |
| 42 | Tlr2 | 9054 | 0.102 | -0.0917 | No |
| 43 | Il4ra | 9148 | 0.100 | -0.0928 | No |
| 44 | Tap2 | 9345 | 0.094 | -0.0979 | No |
| 45 | Il4 | 9392 | 0.093 | -0.0975 | No |
| 46 | Il2 | 9629 | 0.085 | -0.1042 | No |
| 47 | Icosl | 10038 | 0.075 | -0.1174 | No |
| 48 | Ncr1 | 10147 | 0.071 | -0.1198 | No |
| 49 | Galnt1 | 10454 | 0.062 | -0.1296 | No |
| 50 | Eif3j1 | 10562 | 0.059 | -0.1321 | No |
| 51 | Akt1 | 10736 | 0.054 | -0.1372 | No |
| 52 | Il7 | 10901 | 0.049 | -0.1421 | No |
| 53 | F2r | 10975 | 0.047 | -0.1438 | No |
| 54 | H2-DMb2 | 11111 | 0.043 | -0.1477 | No |
| 55 | Bcat1 | 11125 | 0.043 | -0.1473 | No |
| 56 | Il1b | 11203 | 0.040 | -0.1492 | No |
| 57 | Klrd1 | 11246 | 0.039 | -0.1498 | No |
| 58 | Itk | 11601 | 0.030 | -0.1621 | No |
| 59 | Cd79a | 11911 | 0.023 | -0.1728 | No |
| 60 | Glmn | 11938 | 0.022 | -0.1733 | No |
| 61 | H2-Ob | 12052 | 0.019 | -0.1770 | No |
| 62 | Gzmb | 12259 | 0.014 | -0.1842 | No |
| 63 | Ikbkb | 12648 | 0.003 | -0.1982 | No |
| 64 | Tapbp | 12661 | 0.003 | -0.1986 | No |
| 65 | Wars1 | 13277 | -0.004 | -0.2209 | No |
| 66 | Ripk2 | 13655 | -0.014 | -0.2344 | No |
| 67 | Ccr1 | 13755 | -0.017 | -0.2376 | No |
| 68 | Lcp2 | 13928 | -0.022 | -0.2434 | No |
| 69 | Hif1a | 14453 | -0.037 | -0.2617 | No |
| 70 | Il11 | 14473 | -0.038 | -0.2615 | No |
| 71 | Acvr2a | 14488 | -0.038 | -0.2612 | No |
| 72 | Ptpn6 | 15173 | -0.058 | -0.2848 | No |
| 73 | Flna | 15182 | -0.058 | -0.2838 | No |
| 74 | Cd47 | 15659 | -0.073 | -0.2995 | No |
| 75 | Eif3d | 15944 | -0.081 | -0.3081 | No |
| 76 | Ltb | 15967 | -0.081 | -0.3071 | No |
| 77 | Socs5 | 16205 | -0.087 | -0.3138 | No |
| 78 | Ets1 | 16392 | -0.092 | -0.3185 | No |
| 79 | Cd40 | 16564 | -0.098 | -0.3226 | No |
| 80 | Ccr5 | 16669 | -0.101 | -0.3241 | No |
| 81 | Csf1 | 16754 | -0.104 | -0.3249 | No |
| 82 | Bcl3 | 16950 | -0.110 | -0.3295 | No |
| 83 | Cd86 | 16988 | -0.111 | -0.3284 | No |
| 84 | Cd2 | 17237 | -0.119 | -0.3348 | No |
| 85 | Stat4 | 17506 | -0.125 | -0.3418 | No |
| 86 | Tpd52 | 17684 | -0.131 | -0.3454 | No |
| 87 | Ptprc | 17698 | -0.131 | -0.3429 | No |
| 88 | Mtif2 | 17837 | -0.136 | -0.3449 | No |
| 89 | Tlr1 | 17840 | -0.136 | -0.3420 | No |
| 90 | Crtam | 17960 | -0.139 | -0.3432 | No |
| 91 | Irf4 | 18115 | -0.142 | -0.3457 | No |
| 92 | Npm1 | 18152 | -0.143 | -0.3438 | No |
| 93 | Tap1 | 18352 | -0.149 | -0.3478 | No |
| 94 | Pf4 | 18549 | -0.155 | -0.3515 | No |
| 95 | Fasl | 18589 | -0.157 | -0.3494 | No |
| 96 | H2-Oa | 18892 | -0.167 | -0.3567 | No |
| 97 | H2-DMa | 19058 | -0.172 | -0.3589 | No |
| 98 | Csk | 19111 | -0.174 | -0.3569 | No |
| 99 | Hdac9 | 19308 | -0.181 | -0.3600 | No |
| 100 | Il16 | 19446 | -0.186 | -0.3609 | No |
| 101 | Cd1d2 | 19779 | -0.199 | -0.3686 | No |
| 102 | Il15 | 19786 | -0.199 | -0.3644 | No |
| 103 | Il27ra | 19890 | -0.203 | -0.3636 | No |
| 104 | Degs1 | 20076 | -0.208 | -0.3657 | No |
| 105 | Rps3a1 | 20120 | -0.210 | -0.3626 | No |
| 106 | Il12a | 20150 | -0.211 | -0.3590 | No |
| 107 | Ube2d1 | 20188 | -0.213 | -0.3556 | No |
| 108 | Ereg | 20293 | -0.216 | -0.3546 | No |
| 109 | Il12rb1 | 20445 | -0.218 | -0.3553 | No |
| 110 | Il10 | 20865 | -0.231 | -0.3654 | No |
| 111 | Was | 20975 | -0.234 | -0.3642 | No |
| 112 | Itgal | 21006 | -0.236 | -0.3600 | No |
| 113 | Map4k1 | 21156 | -0.242 | -0.3601 | No |
| 114 | H2-Aa | 21304 | -0.248 | -0.3599 | No |
| 115 | Ly75 | 21463 | -0.255 | -0.3600 | No |
| 116 | Itgb2 | 22167 | -0.278 | -0.3794 | Yes |
| 117 | Rpl9 | 22290 | -0.283 | -0.3776 | Yes |
| 118 | Igsf6 | 22354 | -0.286 | -0.3735 | Yes |
| 119 | Socs1 | 22513 | -0.293 | -0.3728 | Yes |
| 120 | Ifngr1 | 22541 | -0.294 | -0.3673 | Yes |
| 121 | Ccr2 | 22554 | -0.295 | -0.3611 | Yes |
| 122 | Cfp | 22800 | -0.301 | -0.3634 | Yes |
| 123 | Il18 | 23169 | -0.319 | -0.3697 | Yes |
| 124 | Ifnar2 | 23263 | -0.323 | -0.3659 | Yes |
| 125 | Bcl10 | 23362 | -0.327 | -0.3622 | Yes |
| 126 | Rps9 | 23442 | -0.332 | -0.3577 | Yes |
| 127 | Trat1 | 23782 | -0.346 | -0.3624 | Yes |
| 128 | Eif5a | 23810 | -0.348 | -0.3556 | Yes |
| 129 | Cd3d | 23887 | -0.353 | -0.3505 | Yes |
| 130 | Ccnd2 | 24017 | -0.361 | -0.3472 | Yes |
| 131 | Nme1 | 24330 | -0.380 | -0.3501 | Yes |
| 132 | Stab1 | 24348 | -0.381 | -0.3423 | Yes |
| 133 | Prkcb | 24682 | -0.398 | -0.3456 | Yes |
| 134 | Lyn | 24767 | -0.405 | -0.3396 | Yes |
| 135 | Icam1 | 24835 | -0.408 | -0.3330 | Yes |
| 136 | Ccl5 | 24921 | -0.412 | -0.3270 | Yes |
| 137 | Psmb10 | 25022 | -0.418 | -0.3213 | Yes |
| 138 | Ifngr2 | 25182 | -0.424 | -0.3177 | Yes |
| 139 | Elf4 | 25405 | -0.439 | -0.3160 | Yes |
| 140 | Tgfb1 | 25418 | -0.440 | -0.3067 | Yes |
| 141 | Cd80 | 25455 | -0.443 | -0.2982 | Yes |
| 142 | St8sia4 | 25690 | -0.463 | -0.2964 | Yes |
| 143 | Gpr65 | 25705 | -0.464 | -0.2866 | Yes |
| 144 | Cd3e | 25757 | -0.468 | -0.2781 | Yes |
| 145 | Cd3g | 25787 | -0.470 | -0.2687 | Yes |
| 146 | Rpl39-ps | 25976 | -0.486 | -0.2647 | Yes |
| 147 | Tnf | 25999 | -0.488 | -0.2547 | Yes |
| 148 | Il2rg | 26230 | -0.515 | -0.2516 | Yes |
| 149 | Irf8 | 26448 | -0.546 | -0.2473 | Yes |
| 150 | B2m | 26522 | -0.558 | -0.2376 | Yes |
| 151 | Il6 | 26547 | -0.562 | -0.2260 | Yes |
| 152 | Elane | 26669 | -0.580 | -0.2175 | Yes |
| 153 | Cd96 | 26678 | -0.583 | -0.2048 | Yes |
| 154 | Srgn | 26762 | -0.600 | -0.1945 | Yes |
| 155 | Cdkn2a | 26810 | -0.607 | -0.1827 | Yes |
| 156 | Ly86 | 26849 | -0.613 | -0.1705 | Yes |
| 157 | Ctss | 26872 | -0.617 | -0.1576 | Yes |
| 158 | Fas | 26888 | -0.621 | -0.1443 | Yes |
| 159 | Capg | 26981 | -0.634 | -0.1336 | Yes |
| 160 | Cd74 | 26997 | -0.637 | -0.1200 | Yes |
| 161 | Il18rap | 27034 | -0.647 | -0.1069 | Yes |
| 162 | Inhba | 27090 | -0.665 | -0.0941 | Yes |
| 163 | Cd7 | 27152 | -0.685 | -0.0811 | Yes |
| 164 | C2 | 27280 | -0.724 | -0.0697 | Yes |
| 165 | Spi1 | 27459 | -0.845 | -0.0573 | Yes |
| 166 | Zap70 | 27483 | -0.865 | -0.0390 | Yes |
| 167 | Cd28 | 27485 | -0.865 | -0.0198 | Yes |
| 168 | Ncf4 | 27575 | -1.080 | 0.0010 | Yes |

