Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	MEP.MEP.ery_Pheno.cls #Group1_versus_Group2.MEP.ery_Pheno.cls #Group1_versus_Group2_repos
Phenotype	MEP.ery_Pheno.cls#Group1_versus_Group2_repos
Upregulated in class	1
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.24471971
Normalized Enrichment Score (NES)	-1.0213395
Nominal p-value	0.4333996
FDR q-value	0.8770577
FWER p-Value	0.977

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Tnfrsf1a	900	0.530	-0.0026	No
2	Itpr2	2703	0.357	-0.0478	No
3	Prkaa2	2998	0.338	-0.0393	No
4	Gna14	3093	0.334	-0.0237	No
5	Slc2a1	3205	0.327	-0.0092	No
6	Fgf22	3983	0.285	-0.0212	No
7	Plcg1	4155	0.278	-0.0117	No
8	Cxcr4	4854	0.247	-0.0230	No
9	Lck	4971	0.241	-0.0135	No
10	Grk2	5092	0.236	-0.0044	No
11	Dapp1	5722	0.214	-0.0152	No
12	Map3k7	5780	0.212	-0.0052	No
13	Tiam1	5833	0.210	0.0048	No
14	Sfn	5860	0.209	0.0158	No
15	Camk4	6044	0.200	0.0205	No
16	Mknk2	7464	0.155	-0.0223	No
17	Mapk8	7546	0.151	-0.0166	No
18	Cab39l	7632	0.148	-0.0113	No
19	Traf2	7690	0.147	-0.0050	No
20	Rptor	7816	0.142	-0.0015	No
21	Sla	7962	0.138	0.0011	No
22	Tbk1	8274	0.128	-0.0029	No
23	Map2k6	9042	0.106	-0.0248	No
24	Nod1	9151	0.103	-0.0229	No
25	Grb2	9427	0.095	-0.0274	No
26	Prkcb	10823	0.059	-0.0748	No
27	Pten	10925	0.056	-0.0753	No
28	Mapkap1	11024	0.053	-0.0758	No
29	Adcy2	11287	0.047	-0.0827	No
30	Mapk9	11313	0.046	-0.0810	No
31	Arhgdia	11392	0.044	-0.0813	No
32	Pik3r3	11432	0.044	-0.0802	No
33	Ralb	11548	0.040	-0.0821	No
34	Pikfyve	12073	0.029	-0.0996	No
35	Mknk1	12323	0.023	-0.1073	No
36	Il2rg	12422	0.021	-0.1097	No
37	Pin1	12478	0.020	-0.1106	No
38	Egfr	12530	0.018	-0.1114	No
39	Gsk3b	12855	0.011	-0.1225	No
40	Ddit3	12950	0.009	-0.1254	No
41	Akt1s1	13101	0.005	-0.1306	No
42	Ube2n	13210	0.003	-0.1344	No
43	Tsc2	13592	-0.002	-0.1481	No
44	E2f1	14210	-0.015	-0.1697	No
45	Raf1	14544	-0.021	-0.1806	No
46	Stat2	14921	-0.031	-0.1925	No
47	Cdkn1b	15044	-0.033	-0.1951	No
48	Nck1	15144	-0.036	-0.1966	No
49	Mapk1	15410	-0.042	-0.2039	No
50	Pdk1	15650	-0.048	-0.2099	No
51	Rps6ka3	16185	-0.060	-0.2259	No
52	Irak4	16408	-0.066	-0.2302	No
53	Pfn1	16683	-0.073	-0.2360	No
54	Ripk1	16923	-0.079	-0.2403	Yes
55	Vav3	16956	-0.079	-0.2369	Yes
56	Cdk2	16969	-0.080	-0.2328	Yes
57	Pak4	16975	-0.080	-0.2285	Yes
58	Ywhab	17014	-0.081	-0.2253	Yes
59	Eif4e	17028	-0.081	-0.2211	Yes
60	Ptpn11	17332	-0.088	-0.2272	Yes
61	Smad2	17360	-0.089	-0.2231	Yes
62	Calr	17463	-0.091	-0.2216	Yes
63	Hsp90b1	17575	-0.094	-0.2203	Yes
64	Actr3	18187	-0.109	-0.2363	Yes
65	Ap2m1	18320	-0.112	-0.2347	Yes
66	Fgf17	18347	-0.113	-0.2292	Yes
67	Atf1	18416	-0.114	-0.2252	Yes
68	Actr2	18686	-0.122	-0.2281	Yes
69	Cltc	18717	-0.122	-0.2222	Yes
70	Prkag1	18863	-0.127	-0.2203	Yes
71	Rac1	19103	-0.133	-0.2214	Yes
72	Ube2d3	19156	-0.134	-0.2157	Yes
73	Cab39	19160	-0.134	-0.2081	Yes
74	Rit1	19231	-0.137	-0.2029	Yes
75	Prkar2a	19551	-0.143	-0.2064	Yes
76	Ecsit	19556	-0.143	-0.1984	Yes
77	Arf1	19790	-0.148	-0.1985	Yes
78	Cdk4	19809	-0.148	-0.1907	Yes
79	Csnk2b	20031	-0.155	-0.1899	Yes
80	Ppp2r1b	20050	-0.156	-0.1817	Yes
81	Ngf	20102	-0.157	-0.1746	Yes
82	Sqstm1	20153	-0.159	-0.1673	Yes
83	Acaca	20644	-0.173	-0.1753	Yes
84	Them4	20870	-0.180	-0.1732	Yes
85	Arpc3	20895	-0.181	-0.1638	Yes
86	Cdk1	21145	-0.189	-0.1622	Yes
87	Fasl	21356	-0.197	-0.1586	Yes
88	Plcb1	21867	-0.216	-0.1649	Yes
89	Hras	22669	-0.249	-0.1798	Yes
90	Mapk10	23151	-0.272	-0.1819	Yes
91	Il4	23615	-0.291	-0.1821	Yes
92	Pla2g12a	23637	-0.292	-0.1663	Yes
93	Nfkbib	24186	-0.322	-0.1679	Yes
94	Rps6ka1	24412	-0.333	-0.1572	Yes
95	Map2k3	24970	-0.366	-0.1567	Yes
96	Cfl1	25042	-0.372	-0.1381	Yes
97	Akt1	25677	-0.422	-0.1372	Yes
98	Ppp1ca	25738	-0.429	-0.1150	Yes
99	Fgf6	25841	-0.438	-0.0938	Yes
100	Myd88	25862	-0.439	-0.0696	Yes
101	Trib3	26524	-0.515	-0.0643	Yes
102	Pitx2	26613	-0.531	-0.0374	Yes
103	Cdkn1a	27081	-0.628	-0.0186	Yes
104	Dusp3	27207	-0.660	0.0144	Yes