| Dataset | MEP.MEP.ery_Pheno.cls #Group1_versus_Group2.MEP.ery_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | MEP.ery_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | -0.314325 |
| Normalized Enrichment Score (NES) | -0.9709798 |
| Nominal p-value | 0.5641548 |
| FDR q-value | 0.9107597 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Insig1 | 259 | 0.718 | 0.0113 | No |
| 2 | Dhcr24 | 792 | 0.548 | 0.0078 | No |
| 3 | Igfbp5 | 1030 | 0.508 | 0.0139 | No |
| 4 | Stard4 | 1326 | 0.473 | 0.0168 | No |
| 5 | Ldlr | 1861 | 0.420 | 0.0095 | No |
| 6 | Btg2 | 2547 | 0.368 | -0.0049 | No |
| 7 | Cyp51 | 2798 | 0.352 | -0.0038 | No |
| 8 | Slc2a1 | 3205 | 0.327 | -0.0092 | No |
| 9 | Slc1a5 | 3412 | 0.316 | -0.0076 | No |
| 10 | Dhcr7 | 3772 | 0.297 | -0.0121 | No |
| 11 | Tes | 3842 | 0.294 | -0.0061 | No |
| 12 | Itgb2 | 4303 | 0.271 | -0.0150 | No |
| 13 | Idi1 | 4515 | 0.261 | -0.0152 | No |
| 14 | Pgm1 | 4657 | 0.255 | -0.0130 | No |
| 15 | Gbe1 | 4845 | 0.247 | -0.0126 | No |
| 16 | Cxcr4 | 4854 | 0.247 | -0.0058 | No |
| 17 | Tmem97 | 4981 | 0.241 | -0.0034 | No |
| 18 | Sytl2 | 5512 | 0.222 | -0.0163 | No |
| 19 | Dapp1 | 5722 | 0.214 | -0.0177 | No |
| 20 | Cd9 | 5759 | 0.212 | -0.0129 | No |
| 21 | Elovl6 | 5895 | 0.207 | -0.0119 | No |
| 22 | Tm7sf2 | 6165 | 0.196 | -0.0160 | No |
| 23 | Eno1b | 6724 | 0.176 | -0.0313 | No |
| 24 | Add3 | 6739 | 0.175 | -0.0267 | No |
| 25 | Glrx | 7189 | 0.160 | -0.0384 | No |
| 26 | Fads1 | 7669 | 0.147 | -0.0516 | No |
| 27 | Mllt11 | 7686 | 0.147 | -0.0480 | No |
| 28 | Ung | 7889 | 0.140 | -0.0513 | No |
| 29 | Sla | 7962 | 0.138 | -0.0499 | No |
| 30 | Sc5d | 8261 | 0.129 | -0.0571 | No |
| 31 | Tbk1 | 8274 | 0.128 | -0.0538 | No |
| 32 | Fads2 | 8301 | 0.128 | -0.0511 | No |
| 33 | Qdpr | 8946 | 0.109 | -0.0714 | No |
| 34 | Dhfr | 9214 | 0.101 | -0.0782 | No |
| 35 | Psme3 | 9653 | 0.090 | -0.0916 | No |
| 36 | Rpa1 | 9959 | 0.082 | -0.1004 | No |
| 37 | Idh1 | 9966 | 0.082 | -0.0982 | No |
| 38 | Cfp | 10166 | 0.076 | -0.1033 | No |
| 39 | Fgl2 | 10234 | 0.074 | -0.1036 | No |
| 40 | Skap2 | 10338 | 0.071 | -0.1053 | No |
| 41 | Sqle | 10451 | 0.068 | -0.1074 | No |
| 42 | Fdxr | 10528 | 0.066 | -0.1082 | No |
| 43 | Niban1 | 10914 | 0.056 | -0.1207 | No |
| 44 | Mthfd2l | 10996 | 0.054 | -0.1220 | No |
| 45 | Pik3r3 | 11432 | 0.044 | -0.1367 | No |
| 46 | Tomm40 | 11498 | 0.042 | -0.1378 | No |
| 47 | Polr3g | 11722 | 0.036 | -0.1449 | No |
| 48 | Adipor2 | 11981 | 0.031 | -0.1534 | No |
| 49 | Acly | 12112 | 0.028 | -0.1574 | No |
| 50 | Hmgcr | 12162 | 0.027 | -0.1584 | No |
| 51 | Gsk3b | 12855 | 0.011 | -0.1833 | No |
| 52 | Ddit3 | 12950 | 0.009 | -0.1865 | No |
| 53 | Atp2a2 | 13060 | 0.006 | -0.1903 | No |
| 54 | Plod2 | 13092 | 0.005 | -0.1913 | No |
| 55 | Ctsc | 13124 | 0.005 | -0.1922 | No |
| 56 | Slc2a3 | 13198 | 0.003 | -0.1948 | No |
| 57 | Srd5a1 | 13581 | -0.002 | -0.2087 | No |
| 58 | Gga2 | 13647 | -0.003 | -0.2110 | No |
| 59 | G6pdx | 13838 | -0.007 | -0.2177 | No |
| 60 | Canx | 14086 | -0.012 | -0.2264 | No |
| 61 | Mcm4 | 14088 | -0.012 | -0.2260 | No |
| 62 | Gmps | 14768 | -0.027 | -0.2500 | No |
| 63 | Ppp1r15a | 14802 | -0.028 | -0.2504 | No |
| 64 | Egln3 | 14855 | -0.029 | -0.2515 | No |
| 65 | Me1 | 15137 | -0.036 | -0.2607 | No |
| 66 | Hmgcs1 | 15152 | -0.036 | -0.2602 | No |
| 67 | Ldha | 15199 | -0.037 | -0.2608 | No |
| 68 | Wars1 | 15593 | -0.047 | -0.2738 | No |
| 69 | Pdk1 | 15650 | -0.048 | -0.2744 | No |
| 70 | Sdf2l1 | 15712 | -0.049 | -0.2752 | No |
| 71 | Psmg1 | 15714 | -0.049 | -0.2738 | No |
| 72 | Cyb5b | 15718 | -0.049 | -0.2725 | No |
| 73 | Ccng1 | 15720 | -0.049 | -0.2711 | No |
| 74 | Nup205 | 15784 | -0.050 | -0.2720 | No |
| 75 | Immt | 15809 | -0.051 | -0.2714 | No |
| 76 | Cdc25a | 15968 | -0.055 | -0.2755 | No |
| 77 | Aldoa | 16187 | -0.060 | -0.2818 | No |
| 78 | Sord | 16195 | -0.060 | -0.2803 | No |
| 79 | Gla | 16234 | -0.061 | -0.2799 | No |
| 80 | Uchl5 | 16424 | -0.066 | -0.2849 | No |
| 81 | Nfyc | 16447 | -0.067 | -0.2837 | No |
| 82 | Edem1 | 16448 | -0.067 | -0.2818 | No |
| 83 | Slc7a5 | 16728 | -0.074 | -0.2898 | No |
| 84 | Pno1 | 16742 | -0.075 | -0.2882 | No |
| 85 | Psmd14 | 17001 | -0.080 | -0.2952 | No |
| 86 | Arpc5l | 17090 | -0.082 | -0.2961 | No |
| 87 | Calr | 17463 | -0.091 | -0.3070 | No |
| 88 | Rdh11 | 17516 | -0.093 | -0.3062 | No |
| 89 | Ppa1 | 17571 | -0.094 | -0.3055 | No |
| 90 | Hsp90b1 | 17575 | -0.094 | -0.3028 | No |
| 91 | Ero1a | 17629 | -0.096 | -0.3020 | No |
| 92 | Phgdh | 17968 | -0.105 | -0.3113 | Yes |
| 93 | Pitpnb | 17982 | -0.105 | -0.3087 | Yes |
| 94 | Ccnf | 18054 | -0.106 | -0.3082 | Yes |
| 95 | Actr3 | 18187 | -0.109 | -0.3099 | Yes |
| 96 | Hspa5 | 18189 | -0.109 | -0.3068 | Yes |
| 97 | Ssr1 | 18206 | -0.110 | -0.3042 | Yes |
| 98 | Ppia | 18233 | -0.110 | -0.3019 | Yes |
| 99 | Fkbp2 | 18261 | -0.111 | -0.2997 | Yes |
| 100 | Tcea1 | 18405 | -0.114 | -0.3016 | Yes |
| 101 | Atp6v1d | 18451 | -0.115 | -0.2999 | Yes |
| 102 | Mcm2 | 18508 | -0.117 | -0.2986 | Yes |
| 103 | Nufip1 | 18525 | -0.117 | -0.2958 | Yes |
| 104 | Lta4h | 18557 | -0.118 | -0.2935 | Yes |
| 105 | Eef1e1 | 18589 | -0.119 | -0.2912 | Yes |
| 106 | Tuba4a | 18623 | -0.120 | -0.2889 | Yes |
| 107 | Cth | 18683 | -0.122 | -0.2876 | Yes |
| 108 | Actr2 | 18686 | -0.122 | -0.2841 | Yes |
| 109 | Psma3 | 18819 | -0.125 | -0.2853 | Yes |
| 110 | Psmd13 | 18870 | -0.127 | -0.2834 | Yes |
| 111 | Hk2 | 18976 | -0.130 | -0.2835 | Yes |
| 112 | Slc1a4 | 19108 | -0.133 | -0.2844 | Yes |
| 113 | Ifi30 | 19124 | -0.133 | -0.2811 | Yes |
| 114 | Ube2d3 | 19156 | -0.134 | -0.2784 | Yes |
| 115 | Nmt1 | 19207 | -0.136 | -0.2763 | Yes |
| 116 | Rit1 | 19231 | -0.137 | -0.2731 | Yes |
| 117 | Txnrd1 | 19327 | -0.139 | -0.2726 | Yes |
| 118 | Gclc | 19481 | -0.140 | -0.2741 | Yes |
| 119 | Psmc6 | 19579 | -0.143 | -0.2735 | Yes |
| 120 | Hspa4 | 19602 | -0.144 | -0.2701 | Yes |
| 121 | Hmbs | 19655 | -0.145 | -0.2678 | Yes |
| 122 | Prdx1 | 19663 | -0.146 | -0.2639 | Yes |
| 123 | Hspd1 | 19800 | -0.148 | -0.2645 | Yes |
| 124 | Pgk1 | 19905 | -0.151 | -0.2640 | Yes |
| 125 | Coro1a | 19914 | -0.151 | -0.2599 | Yes |
| 126 | Bub1 | 19932 | -0.152 | -0.2561 | Yes |
| 127 | Slc37a4 | 20008 | -0.155 | -0.2543 | Yes |
| 128 | P4ha1 | 20046 | -0.156 | -0.2512 | Yes |
| 129 | Sqstm1 | 20153 | -0.159 | -0.2504 | Yes |
| 130 | Got1 | 20199 | -0.161 | -0.2474 | Yes |
| 131 | Sec11a | 20209 | -0.161 | -0.2431 | Yes |
| 132 | Uso1 | 20308 | -0.164 | -0.2419 | Yes |
| 133 | Gtf2h1 | 20328 | -0.165 | -0.2378 | Yes |
| 134 | Pdap1 | 20347 | -0.165 | -0.2337 | Yes |
| 135 | Aurka | 20431 | -0.166 | -0.2319 | Yes |
| 136 | Pfkl | 20465 | -0.167 | -0.2283 | Yes |
| 137 | Psmc2 | 20554 | -0.170 | -0.2266 | Yes |
| 138 | Acaca | 20644 | -0.173 | -0.2248 | Yes |
| 139 | Rab1a | 20706 | -0.174 | -0.2220 | Yes |
| 140 | Nampt | 20876 | -0.180 | -0.2230 | Yes |
| 141 | M6pr | 20891 | -0.181 | -0.2183 | Yes |
| 142 | Xbp1 | 20915 | -0.182 | -0.2138 | Yes |
| 143 | Psma4 | 20982 | -0.184 | -0.2109 | Yes |
| 144 | Ddx39a | 21022 | -0.185 | -0.2070 | Yes |
| 145 | Ifrd1 | 21061 | -0.186 | -0.2030 | Yes |
| 146 | Slc6a6 | 21084 | -0.187 | -0.1984 | Yes |
| 147 | Rrm2 | 21094 | -0.187 | -0.1933 | Yes |
| 148 | Eif2s2 | 21136 | -0.188 | -0.1894 | Yes |
| 149 | Hspe1 | 21172 | -0.190 | -0.1851 | Yes |
| 150 | Gpi1 | 21244 | -0.192 | -0.1822 | Yes |
| 151 | Stip1 | 21280 | -0.194 | -0.1778 | Yes |
| 152 | Lgmn | 21396 | -0.198 | -0.1763 | Yes |
| 153 | Tpi1 | 21424 | -0.199 | -0.1715 | Yes |
| 154 | Elovl5 | 21450 | -0.200 | -0.1667 | Yes |
| 155 | Ddit4 | 21482 | -0.201 | -0.1620 | Yes |
| 156 | Ykt6 | 21717 | -0.209 | -0.1645 | Yes |
| 157 | Serp1 | 21723 | -0.209 | -0.1586 | Yes |
| 158 | Rrp9 | 21764 | -0.211 | -0.1539 | Yes |
| 159 | Psph | 21798 | -0.213 | -0.1490 | Yes |
| 160 | Ebp | 21812 | -0.213 | -0.1433 | Yes |
| 161 | Cops5 | 21869 | -0.216 | -0.1391 | Yes |
| 162 | Bcat1 | 21958 | -0.221 | -0.1359 | Yes |
| 163 | Plk1 | 22414 | -0.238 | -0.1456 | Yes |
| 164 | Rpn1 | 22595 | -0.247 | -0.1450 | Yes |
| 165 | Tfrc | 22691 | -0.250 | -0.1412 | Yes |
| 166 | Etf1 | 22692 | -0.250 | -0.1340 | Yes |
| 167 | Gsr | 22743 | -0.252 | -0.1285 | Yes |
| 168 | Psmd12 | 22838 | -0.257 | -0.1245 | Yes |
| 169 | Asns | 22843 | -0.257 | -0.1172 | Yes |
| 170 | Cct6a | 22996 | -0.263 | -0.1152 | Yes |
| 171 | Hspa9 | 23071 | -0.268 | -0.1101 | Yes |
| 172 | Tubg1 | 23093 | -0.269 | -0.1031 | Yes |
| 173 | Abcf2 | 23107 | -0.270 | -0.0957 | Yes |
| 174 | Psat1 | 23284 | -0.277 | -0.0941 | Yes |
| 175 | Nupr1 | 23342 | -0.278 | -0.0882 | Yes |
| 176 | Acsl3 | 23858 | -0.305 | -0.0982 | Yes |
| 177 | Pnp | 23938 | -0.311 | -0.0920 | Yes |
| 178 | Nfkbib | 24186 | -0.322 | -0.0917 | Yes |
| 179 | Bhlhe40 | 24343 | -0.329 | -0.0879 | Yes |
| 180 | Psmc4 | 24397 | -0.331 | -0.0803 | Yes |
| 181 | Psmb5 | 24430 | -0.334 | -0.0717 | Yes |
| 182 | Ufm1 | 24515 | -0.339 | -0.0650 | Yes |
| 183 | Map2k3 | 24970 | -0.366 | -0.0710 | Yes |
| 184 | Ak4 | 25131 | -0.377 | -0.0659 | Yes |
| 185 | Cacybp | 25397 | -0.398 | -0.0641 | Yes |
| 186 | Mthfd2 | 25463 | -0.403 | -0.0548 | Yes |
| 187 | Serpinh1 | 25662 | -0.421 | -0.0498 | Yes |
| 188 | Stc1 | 25743 | -0.429 | -0.0403 | Yes |
| 189 | Slc7a11 | 25904 | -0.443 | -0.0333 | Yes |
| 190 | Trib3 | 26524 | -0.515 | -0.0410 | Yes |
| 191 | Shmt2 | 26610 | -0.530 | -0.0288 | Yes |
| 192 | Cdkn1a | 27081 | -0.628 | -0.0277 | Yes |
| 193 | Vldlr | 27357 | -0.735 | -0.0165 | Yes |
| 194 | Nfil3 | 27503 | -0.877 | 0.0036 | Yes |

