| Dataset | MEP.MEP.ery_Pheno.cls #Group1_versus_Group2.MEP.ery_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | MEP.ery_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | -0.3065596 |
| Normalized Enrichment Score (NES) | -1.4675062 |
| Nominal p-value | 0.1352459 |
| FDR q-value | 0.5800961 |
| FWER p-Value | 0.554 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Meis1 | 2904 | 0.345 | -0.0907 | No |
| 2 | H2bc12 | 3711 | 0.300 | -0.1069 | No |
| 3 | Marcks | 3736 | 0.298 | -0.0946 | No |
| 4 | Slc12a2 | 4211 | 0.275 | -0.0997 | No |
| 5 | Smad3 | 5033 | 0.238 | -0.1191 | No |
| 6 | Ccnd1 | 5463 | 0.224 | -0.1249 | No |
| 7 | Foxn3 | 5838 | 0.210 | -0.1292 | No |
| 8 | Egf | 6103 | 0.198 | -0.1301 | No |
| 9 | Ewsr1 | 6667 | 0.178 | -0.1428 | No |
| 10 | Ube2s | 6789 | 0.174 | -0.1395 | No |
| 11 | Tgfb1 | 6811 | 0.173 | -0.1326 | No |
| 12 | Mnat1 | 7170 | 0.161 | -0.1386 | No |
| 13 | E2f2 | 7888 | 0.140 | -0.1585 | No |
| 14 | Cdc45 | 8284 | 0.128 | -0.1673 | No |
| 15 | Srsf2 | 8873 | 0.112 | -0.1838 | No |
| 16 | Dtymk | 9183 | 0.102 | -0.1906 | No |
| 17 | Tle3 | 9222 | 0.101 | -0.1875 | No |
| 18 | Rad21 | 9262 | 0.100 | -0.1845 | No |
| 19 | Hif1a | 9385 | 0.097 | -0.1847 | No |
| 20 | Abl1 | 9390 | 0.097 | -0.1805 | No |
| 21 | Katna1 | 9407 | 0.096 | -0.1769 | No |
| 22 | Nup98 | 9822 | 0.085 | -0.1882 | No |
| 23 | Nup50 | 9858 | 0.084 | -0.1857 | No |
| 24 | Hnrnpd | 10003 | 0.081 | -0.1874 | No |
| 25 | Exo1 | 10059 | 0.079 | -0.1859 | No |
| 26 | Numa1 | 10269 | 0.073 | -0.1903 | No |
| 27 | Sqle | 10451 | 0.068 | -0.1939 | No |
| 28 | E2f3 | 10457 | 0.068 | -0.1911 | No |
| 29 | Stag1 | 10579 | 0.065 | -0.1927 | No |
| 30 | Efna5 | 10632 | 0.064 | -0.1917 | No |
| 31 | Arid4a | 10661 | 0.063 | -0.1900 | No |
| 32 | Myc | 10777 | 0.060 | -0.1915 | No |
| 33 | Ss18 | 10978 | 0.055 | -0.1964 | No |
| 34 | Rbl1 | 11105 | 0.051 | -0.1987 | No |
| 35 | Map3k20 | 11182 | 0.049 | -0.1993 | No |
| 36 | Rad23b | 11262 | 0.048 | -0.2001 | No |
| 37 | Tnpo2 | 11335 | 0.046 | -0.2007 | No |
| 38 | Mcm6 | 11473 | 0.042 | -0.2039 | No |
| 39 | Lig3 | 11483 | 0.042 | -0.2023 | No |
| 40 | Rps6ka5 | 11589 | 0.039 | -0.2044 | No |
| 41 | Atrx | 11650 | 0.038 | -0.2049 | No |
| 42 | Rasal2 | 11754 | 0.035 | -0.2072 | No |
| 43 | Tfdp1 | 12013 | 0.030 | -0.2152 | No |
| 44 | Ilf3 | 12034 | 0.030 | -0.2146 | No |
| 45 | Fancc | 12300 | 0.024 | -0.2233 | No |
| 46 | Pds5b | 12348 | 0.023 | -0.2240 | No |
| 47 | Bub3 | 12447 | 0.020 | -0.2266 | No |
| 48 | Smarcc1 | 12491 | 0.019 | -0.2274 | No |
| 49 | Gins2 | 12595 | 0.017 | -0.2304 | No |
| 50 | Pml | 12732 | 0.014 | -0.2347 | No |
| 51 | Lbr | 12791 | 0.013 | -0.2362 | No |
| 52 | Cdc25b | 13014 | 0.008 | -0.2440 | No |
| 53 | Hus1 | 13179 | 0.004 | -0.2498 | No |
| 54 | Notch2 | 13253 | 0.002 | -0.2524 | No |
| 55 | Pola2 | 13546 | -0.001 | -0.2630 | No |
| 56 | Ythdc1 | 13724 | -0.005 | -0.2693 | No |
| 57 | Stil | 13753 | -0.005 | -0.2701 | No |
| 58 | Ccnt1 | 13831 | -0.007 | -0.2726 | No |
| 59 | Mcm5 | 13873 | -0.008 | -0.2737 | No |
| 60 | Kpnb1 | 13939 | -0.010 | -0.2757 | No |
| 61 | Ezh2 | 14098 | -0.013 | -0.2809 | No |
| 62 | Kif22 | 14177 | -0.014 | -0.2831 | No |
| 63 | E2f1 | 14210 | -0.015 | -0.2836 | No |
| 64 | Mcm3 | 14224 | -0.015 | -0.2834 | No |
| 65 | Bard1 | 14322 | -0.017 | -0.2862 | No |
| 66 | Mybl2 | 14348 | -0.017 | -0.2864 | No |
| 67 | Traip | 14423 | -0.020 | -0.2882 | No |
| 68 | Syncrip | 14441 | -0.020 | -0.2879 | No |
| 69 | G3bp1 | 14465 | -0.021 | -0.2879 | No |
| 70 | Sfpq | 14576 | -0.022 | -0.2909 | No |
| 71 | Wrn | 14638 | -0.024 | -0.2921 | No |
| 72 | Incenp | 14856 | -0.029 | -0.2987 | No |
| 73 | Pttg1 | 14949 | -0.032 | -0.3007 | No |
| 74 | Cdkn1b | 15044 | -0.033 | -0.3026 | No |
| 75 | Mtf2 | 15153 | -0.036 | -0.3050 | Yes |
| 76 | Mapk14 | 15179 | -0.037 | -0.3043 | Yes |
| 77 | H2ax | 15188 | -0.037 | -0.3029 | Yes |
| 78 | Smc2 | 15206 | -0.037 | -0.3019 | Yes |
| 79 | Cul5 | 15221 | -0.038 | -0.3008 | Yes |
| 80 | Brca2 | 15224 | -0.038 | -0.2992 | Yes |
| 81 | Ccnb2 | 15311 | -0.039 | -0.3006 | Yes |
| 82 | Chaf1a | 15428 | -0.042 | -0.3029 | Yes |
| 83 | Cul3 | 15489 | -0.044 | -0.3032 | Yes |
| 84 | Xpo1 | 15500 | -0.044 | -0.3016 | Yes |
| 85 | Espl1 | 15510 | -0.044 | -0.2999 | Yes |
| 86 | Gspt1 | 15517 | -0.045 | -0.2982 | Yes |
| 87 | Casp8ap2 | 15540 | -0.045 | -0.2970 | Yes |
| 88 | Prim2 | 15589 | -0.047 | -0.2967 | Yes |
| 89 | Slc38a1 | 15619 | -0.047 | -0.2956 | Yes |
| 90 | Cdkn2c | 15696 | -0.049 | -0.2963 | Yes |
| 91 | Upf1 | 15707 | -0.049 | -0.2945 | Yes |
| 92 | Nasp | 15741 | -0.050 | -0.2935 | Yes |
| 93 | Chmp1a | 15770 | -0.050 | -0.2923 | Yes |
| 94 | Rad54l | 15823 | -0.051 | -0.2919 | Yes |
| 95 | Ctcf | 15826 | -0.051 | -0.2897 | Yes |
| 96 | Fbxo5 | 15848 | -0.052 | -0.2882 | Yes |
| 97 | Cdc25a | 15968 | -0.055 | -0.2901 | Yes |
| 98 | Cenpf | 15995 | -0.056 | -0.2886 | Yes |
| 99 | Tra2b | 16007 | -0.056 | -0.2865 | Yes |
| 100 | Cdc27 | 16062 | -0.057 | -0.2859 | Yes |
| 101 | Cdc7 | 16110 | -0.058 | -0.2851 | Yes |
| 102 | Pura | 16253 | -0.062 | -0.2875 | Yes |
| 103 | Kif20b | 16334 | -0.064 | -0.2876 | Yes |
| 104 | Knl1 | 16344 | -0.064 | -0.2851 | Yes |
| 105 | Tmpo | 16352 | -0.064 | -0.2825 | Yes |
| 106 | Uck2 | 16489 | -0.068 | -0.2845 | Yes |
| 107 | Slc7a1 | 16495 | -0.068 | -0.2817 | Yes |
| 108 | Srsf10 | 16572 | -0.070 | -0.2814 | Yes |
| 109 | Nsd2 | 16653 | -0.072 | -0.2811 | Yes |
| 110 | Dmd | 16668 | -0.072 | -0.2784 | Yes |
| 111 | Hira | 16673 | -0.073 | -0.2753 | Yes |
| 112 | Slc7a5 | 16728 | -0.074 | -0.2740 | Yes |
| 113 | Kif5b | 16764 | -0.075 | -0.2720 | Yes |
| 114 | Atf5 | 16830 | -0.076 | -0.2710 | Yes |
| 115 | Rpa2 | 16848 | -0.077 | -0.2682 | Yes |
| 116 | Chek1 | 16968 | -0.080 | -0.2690 | Yes |
| 117 | Pole | 17178 | -0.084 | -0.2729 | Yes |
| 118 | Kif15 | 17206 | -0.085 | -0.2702 | Yes |
| 119 | Cul1 | 17260 | -0.086 | -0.2683 | Yes |
| 120 | Dr1 | 17522 | -0.093 | -0.2737 | Yes |
| 121 | Polq | 17530 | -0.093 | -0.2698 | Yes |
| 122 | Prpf4b | 17568 | -0.094 | -0.2670 | Yes |
| 123 | Troap | 17781 | -0.099 | -0.2704 | Yes |
| 124 | Odc1 | 17791 | -0.100 | -0.2663 | Yes |
| 125 | Ccnf | 18054 | -0.106 | -0.2712 | Yes |
| 126 | Nusap1 | 18092 | -0.107 | -0.2678 | Yes |
| 127 | Top2a | 18102 | -0.107 | -0.2634 | Yes |
| 128 | Pafah1b1 | 18197 | -0.110 | -0.2620 | Yes |
| 129 | Smc4 | 18220 | -0.110 | -0.2579 | Yes |
| 130 | Ndc80 | 18363 | -0.113 | -0.2581 | Yes |
| 131 | Lmnb1 | 18461 | -0.116 | -0.2565 | Yes |
| 132 | Suv39h1 | 18473 | -0.116 | -0.2518 | Yes |
| 133 | Mcm2 | 18508 | -0.117 | -0.2479 | Yes |
| 134 | Kif11 | 18527 | -0.117 | -0.2434 | Yes |
| 135 | Cdc6 | 18547 | -0.118 | -0.2389 | Yes |
| 136 | Cul4a | 18571 | -0.118 | -0.2345 | Yes |
| 137 | Top1 | 18588 | -0.119 | -0.2298 | Yes |
| 138 | Aurkb | 18609 | -0.119 | -0.2253 | Yes |
| 139 | Dkc1 | 18620 | -0.120 | -0.2204 | Yes |
| 140 | Hnrnpu | 18786 | -0.125 | -0.2209 | Yes |
| 141 | Odf2 | 18789 | -0.125 | -0.2154 | Yes |
| 142 | Nolc1 | 18834 | -0.126 | -0.2115 | Yes |
| 143 | Tacc3 | 18837 | -0.126 | -0.2059 | Yes |
| 144 | Tent4a | 18846 | -0.126 | -0.2006 | Yes |
| 145 | Pbk | 18847 | -0.127 | -0.1951 | Yes |
| 146 | E2f4 | 18899 | -0.128 | -0.1913 | Yes |
| 147 | Dbf4 | 18997 | -0.131 | -0.1890 | Yes |
| 148 | Kif2c | 19074 | -0.132 | -0.1859 | Yes |
| 149 | Ube2c | 19166 | -0.135 | -0.1833 | Yes |
| 150 | Mki67 | 19590 | -0.143 | -0.1924 | Yes |
| 151 | Orc5 | 19591 | -0.144 | -0.1861 | Yes |
| 152 | Kmt5a | 19649 | -0.145 | -0.1817 | Yes |
| 153 | Cdk4 | 19809 | -0.148 | -0.1810 | Yes |
| 154 | Ttk | 19836 | -0.149 | -0.1753 | Yes |
| 155 | Cks2 | 19851 | -0.150 | -0.1692 | Yes |
| 156 | Hmmr | 19930 | -0.152 | -0.1654 | Yes |
| 157 | Bub1 | 19932 | -0.152 | -0.1587 | Yes |
| 158 | Hmgb3 | 19942 | -0.153 | -0.1522 | Yes |
| 159 | Cenpe | 19977 | -0.154 | -0.1467 | Yes |
| 160 | Smc1a | 20011 | -0.155 | -0.1411 | Yes |
| 161 | Prc1 | 20212 | -0.161 | -0.1412 | Yes |
| 162 | Cbx1 | 20299 | -0.164 | -0.1371 | Yes |
| 163 | Aurka | 20431 | -0.166 | -0.1346 | Yes |
| 164 | Ncl | 20483 | -0.167 | -0.1291 | Yes |
| 165 | Kif23 | 20511 | -0.168 | -0.1226 | Yes |
| 166 | Bcl3 | 20542 | -0.169 | -0.1162 | Yes |
| 167 | Orc6 | 20728 | -0.175 | -0.1152 | Yes |
| 168 | Cdc20 | 20875 | -0.180 | -0.1126 | Yes |
| 169 | Kif4 | 20892 | -0.181 | -0.1052 | Yes |
| 170 | Plk4 | 20993 | -0.184 | -0.1007 | Yes |
| 171 | Ddx39a | 21022 | -0.185 | -0.0936 | Yes |
| 172 | H2az2 | 21144 | -0.189 | -0.0896 | Yes |
| 173 | Cdk1 | 21145 | -0.189 | -0.0813 | Yes |
| 174 | Jpt1 | 21311 | -0.195 | -0.0787 | Yes |
| 175 | Tpx2 | 21351 | -0.197 | -0.0714 | Yes |
| 176 | Cks1b | 21779 | -0.212 | -0.0776 | Yes |
| 177 | Snrpd1 | 21791 | -0.213 | -0.0686 | Yes |
| 178 | Mad2l1 | 21980 | -0.222 | -0.0657 | Yes |
| 179 | Stmn1 | 22264 | -0.232 | -0.0658 | Yes |
| 180 | Cenpa | 22381 | -0.237 | -0.0595 | Yes |
| 181 | Plk1 | 22414 | -0.238 | -0.0502 | Yes |
| 182 | Amd1 | 22497 | -0.242 | -0.0425 | Yes |
| 183 | Racgap1 | 22550 | -0.245 | -0.0335 | Yes |
| 184 | Prmt5 | 23132 | -0.271 | -0.0428 | Yes |
| 185 | Ccna2 | 23350 | -0.278 | -0.0384 | Yes |
| 186 | H2az1 | 23733 | -0.297 | -0.0392 | Yes |
| 187 | Nek2 | 24411 | -0.333 | -0.0492 | Yes |
| 188 | Cdkn3 | 24527 | -0.340 | -0.0383 | Yes |
| 189 | Sap30 | 25391 | -0.397 | -0.0522 | Yes |
| 190 | Srsf1 | 25527 | -0.409 | -0.0391 | Yes |
| 191 | Birc5 | 25590 | -0.416 | -0.0230 | Yes |
| 192 | Hspa8 | 26594 | -0.527 | -0.0363 | Yes |
| 193 | Hmga1b | 27210 | -0.662 | -0.0295 | Yes |
| 194 | Meis2 | 27552 | -0.990 | 0.0018 | Yes |

