| Dataset | MEP.MEP.ery_Pheno.cls #Group1_versus_Group2.MEP.ery_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | MEP.ery_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | -0.3979959 |
| Normalized Enrichment Score (NES) | -1.5934937 |
| Nominal p-value | 0.1125 |
| FDR q-value | 0.7501054 |
| FWER p-Value | 0.317 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Tcf19 | 4435 | 0.264 | -0.1512 | No |
| 2 | E2f8 | 4627 | 0.256 | -0.1478 | No |
| 3 | Pold2 | 6478 | 0.185 | -0.2078 | No |
| 4 | Rfc2 | 6540 | 0.183 | -0.2027 | No |
| 5 | Ube2s | 6789 | 0.174 | -0.2047 | No |
| 6 | Prdx4 | 7742 | 0.145 | -0.2336 | No |
| 7 | Tk1 | 7835 | 0.141 | -0.2312 | No |
| 8 | Ung | 7889 | 0.140 | -0.2275 | No |
| 9 | Mlh1 | 8052 | 0.135 | -0.2280 | No |
| 10 | Cnot9 | 8645 | 0.118 | -0.2448 | No |
| 11 | Pold1 | 8790 | 0.114 | -0.2455 | No |
| 12 | Srsf2 | 8873 | 0.112 | -0.2439 | No |
| 13 | Cenpm | 9187 | 0.102 | -0.2512 | No |
| 14 | Rad21 | 9262 | 0.100 | -0.2499 | No |
| 15 | Pole4 | 9489 | 0.094 | -0.2544 | No |
| 16 | Dscc1 | 9567 | 0.092 | -0.2535 | No |
| 17 | Rpa1 | 9959 | 0.082 | -0.2644 | No |
| 18 | Hnrnpd | 10003 | 0.081 | -0.2627 | No |
| 19 | Timeless | 10343 | 0.071 | -0.2722 | No |
| 20 | Cse1l | 10394 | 0.069 | -0.2713 | No |
| 21 | Nudt21 | 10521 | 0.067 | -0.2732 | No |
| 22 | Stag1 | 10579 | 0.065 | -0.2726 | No |
| 23 | Myc | 10777 | 0.060 | -0.2774 | No |
| 24 | Brms1l | 11069 | 0.052 | -0.2859 | No |
| 25 | Mms22l | 11103 | 0.051 | -0.2850 | No |
| 26 | Pold3 | 11229 | 0.048 | -0.2877 | No |
| 27 | Eed | 11292 | 0.047 | -0.2880 | No |
| 28 | Wdr90 | 11466 | 0.043 | -0.2926 | No |
| 29 | Mcm6 | 11473 | 0.042 | -0.2911 | No |
| 30 | Wee1 | 11597 | 0.039 | -0.2941 | No |
| 31 | Atad2 | 11758 | 0.035 | -0.2985 | No |
| 32 | Mxd3 | 11759 | 0.035 | -0.2971 | No |
| 33 | Tbrg4 | 11951 | 0.032 | -0.3028 | No |
| 34 | Ilf3 | 12034 | 0.030 | -0.3045 | No |
| 35 | Pds5b | 12348 | 0.023 | -0.3150 | No |
| 36 | Rfc1 | 12412 | 0.021 | -0.3165 | No |
| 37 | Diaph3 | 12468 | 0.020 | -0.3177 | No |
| 38 | Tubb5 | 12544 | 0.018 | -0.3197 | No |
| 39 | Pms2 | 12707 | 0.015 | -0.3250 | No |
| 40 | Pan2 | 12719 | 0.015 | -0.3248 | No |
| 41 | Lbr | 12791 | 0.013 | -0.3269 | No |
| 42 | Rfc3 | 12932 | 0.009 | -0.3316 | No |
| 43 | Cdc25b | 13014 | 0.008 | -0.3343 | No |
| 44 | Dclre1b | 13078 | 0.006 | -0.3363 | No |
| 45 | Rnaseh2a | 13158 | 0.004 | -0.3391 | No |
| 46 | Hus1 | 13179 | 0.004 | -0.3396 | No |
| 47 | Rad50 | 13522 | -0.000 | -0.3521 | No |
| 48 | Pola2 | 13546 | -0.001 | -0.3529 | No |
| 49 | Mcm5 | 13873 | -0.008 | -0.3645 | No |
| 50 | Ipo7 | 13885 | -0.008 | -0.3646 | No |
| 51 | Ube2t | 13908 | -0.009 | -0.3650 | No |
| 52 | Mcm4 | 14088 | -0.012 | -0.3711 | No |
| 53 | Ezh2 | 14098 | -0.013 | -0.3709 | No |
| 54 | Gins1 | 14134 | -0.013 | -0.3716 | No |
| 55 | Kif22 | 14177 | -0.014 | -0.3726 | No |
| 56 | Mcm3 | 14224 | -0.015 | -0.3737 | No |
| 57 | Bard1 | 14322 | -0.017 | -0.3765 | No |
| 58 | Prkdc | 14323 | -0.017 | -0.3759 | No |
| 59 | Mybl2 | 14348 | -0.017 | -0.3760 | No |
| 60 | Syncrip | 14441 | -0.020 | -0.3786 | No |
| 61 | Kif18b | 14461 | -0.021 | -0.3784 | No |
| 62 | Nop56 | 14620 | -0.023 | -0.3833 | No |
| 63 | Hells | 14796 | -0.028 | -0.3885 | No |
| 64 | Lig1 | 14803 | -0.028 | -0.3876 | No |
| 65 | Mre11a | 14886 | -0.030 | -0.3894 | No |
| 66 | Mcm7 | 14905 | -0.030 | -0.3888 | No |
| 67 | Nup153 | 14946 | -0.031 | -0.3890 | No |
| 68 | Pttg1 | 14949 | -0.032 | -0.3878 | No |
| 69 | Anp32e | 15024 | -0.033 | -0.3892 | No |
| 70 | Cdkn1b | 15044 | -0.033 | -0.3885 | No |
| 71 | Pnn | 15046 | -0.034 | -0.3872 | No |
| 72 | Cbx5 | 15127 | -0.035 | -0.3887 | No |
| 73 | H2ax | 15188 | -0.037 | -0.3894 | No |
| 74 | Brca2 | 15224 | -0.038 | -0.3892 | No |
| 75 | Asf1b | 15260 | -0.038 | -0.3889 | No |
| 76 | Ccnb2 | 15311 | -0.039 | -0.3891 | No |
| 77 | Msh2 | 15411 | -0.042 | -0.3910 | No |
| 78 | Xpo1 | 15500 | -0.044 | -0.3925 | No |
| 79 | Espl1 | 15510 | -0.044 | -0.3910 | No |
| 80 | Gspt1 | 15517 | -0.045 | -0.3894 | No |
| 81 | Prim2 | 15589 | -0.047 | -0.3901 | No |
| 82 | Ubr7 | 15615 | -0.047 | -0.3891 | No |
| 83 | Cdkn2c | 15696 | -0.049 | -0.3901 | No |
| 84 | Nasp | 15741 | -0.050 | -0.3897 | No |
| 85 | Nup205 | 15784 | -0.050 | -0.3892 | No |
| 86 | Ctcf | 15826 | -0.051 | -0.3886 | No |
| 87 | Cdc25a | 15968 | -0.055 | -0.3915 | No |
| 88 | Tra2b | 16007 | -0.056 | -0.3906 | No |
| 89 | Pcna | 16100 | -0.058 | -0.3917 | No |
| 90 | Xrcc6 | 16107 | -0.058 | -0.3895 | No |
| 91 | Dnmt1 | 16128 | -0.059 | -0.3879 | No |
| 92 | Tmpo | 16352 | -0.064 | -0.3934 | No |
| 93 | Dlgap5 | 16478 | -0.067 | -0.3953 | Yes |
| 94 | Psip1 | 16496 | -0.068 | -0.3932 | Yes |
| 95 | Phf5a | 16531 | -0.069 | -0.3916 | Yes |
| 96 | Cit | 16611 | -0.071 | -0.3916 | Yes |
| 97 | Spag5 | 16634 | -0.072 | -0.3896 | Yes |
| 98 | Rpa2 | 16848 | -0.077 | -0.3942 | Yes |
| 99 | Ccp110 | 16882 | -0.078 | -0.3923 | Yes |
| 100 | Smc3 | 16895 | -0.078 | -0.3896 | Yes |
| 101 | Ppm1d | 16897 | -0.078 | -0.3865 | Yes |
| 102 | Chek1 | 16968 | -0.080 | -0.3858 | Yes |
| 103 | Psmc3ip | 17006 | -0.080 | -0.3839 | Yes |
| 104 | Cdca3 | 17085 | -0.082 | -0.3835 | Yes |
| 105 | Pole | 17178 | -0.084 | -0.3834 | Yes |
| 106 | Rad51ap1 | 17180 | -0.084 | -0.3800 | Yes |
| 107 | Gins3 | 17223 | -0.085 | -0.3781 | Yes |
| 108 | Nup107 | 17233 | -0.086 | -0.3750 | Yes |
| 109 | Slbp | 17484 | -0.092 | -0.3804 | Yes |
| 110 | Dek | 17512 | -0.093 | -0.3776 | Yes |
| 111 | Hmgb2 | 17567 | -0.094 | -0.3758 | Yes |
| 112 | Orc2 | 17720 | -0.098 | -0.3774 | Yes |
| 113 | Usp1 | 17804 | -0.100 | -0.3764 | Yes |
| 114 | Top2a | 18102 | -0.107 | -0.3829 | Yes |
| 115 | Brca1 | 18142 | -0.108 | -0.3800 | Yes |
| 116 | Smc4 | 18220 | -0.110 | -0.3783 | Yes |
| 117 | Exosc8 | 18285 | -0.111 | -0.3762 | Yes |
| 118 | Dctpp1 | 18353 | -0.113 | -0.3741 | Yes |
| 119 | Trp53 | 18406 | -0.114 | -0.3713 | Yes |
| 120 | Lmnb1 | 18461 | -0.116 | -0.3686 | Yes |
| 121 | Suv39h1 | 18473 | -0.116 | -0.3644 | Yes |
| 122 | Cdca8 | 18474 | -0.116 | -0.3597 | Yes |
| 123 | Mcm2 | 18508 | -0.117 | -0.3562 | Yes |
| 124 | Zw10 | 18568 | -0.118 | -0.3536 | Yes |
| 125 | Aurkb | 18609 | -0.119 | -0.3502 | Yes |
| 126 | Prps1 | 18688 | -0.122 | -0.3481 | Yes |
| 127 | Snrpb | 18716 | -0.122 | -0.3442 | Yes |
| 128 | Luc7l3 | 18806 | -0.125 | -0.3424 | Yes |
| 129 | Nolc1 | 18834 | -0.126 | -0.3383 | Yes |
| 130 | Tacc3 | 18837 | -0.126 | -0.3332 | Yes |
| 131 | Kif2c | 19074 | -0.132 | -0.3365 | Yes |
| 132 | Nbn | 19097 | -0.133 | -0.3319 | Yes |
| 133 | Paics | 19113 | -0.133 | -0.3271 | Yes |
| 134 | Melk | 19307 | -0.139 | -0.3285 | Yes |
| 135 | Depdc1a | 19505 | -0.141 | -0.3300 | Yes |
| 136 | Mki67 | 19590 | -0.143 | -0.3273 | Yes |
| 137 | Chek2 | 19594 | -0.144 | -0.3216 | Yes |
| 138 | Asf1a | 19616 | -0.144 | -0.3165 | Yes |
| 139 | Rbbp7 | 19691 | -0.146 | -0.3133 | Yes |
| 140 | Ncapd2 | 19715 | -0.147 | -0.3082 | Yes |
| 141 | Cdk4 | 19809 | -0.148 | -0.3056 | Yes |
| 142 | Smc6 | 19843 | -0.149 | -0.3008 | Yes |
| 143 | Cks2 | 19851 | -0.150 | -0.2950 | Yes |
| 144 | Nap1l1 | 19892 | -0.151 | -0.2904 | Yes |
| 145 | Hmmr | 19930 | -0.152 | -0.2856 | Yes |
| 146 | Hmgb3 | 19942 | -0.153 | -0.2798 | Yes |
| 147 | Cenpe | 19977 | -0.154 | -0.2749 | Yes |
| 148 | Smc1a | 20011 | -0.155 | -0.2698 | Yes |
| 149 | Ppp1r8 | 20038 | -0.156 | -0.2645 | Yes |
| 150 | Gins4 | 20351 | -0.165 | -0.2692 | Yes |
| 151 | Aurka | 20431 | -0.166 | -0.2654 | Yes |
| 152 | Rpa3 | 20572 | -0.170 | -0.2636 | Yes |
| 153 | Orc6 | 20728 | -0.175 | -0.2622 | Yes |
| 154 | Cdc20 | 20875 | -0.180 | -0.2603 | Yes |
| 155 | Kif4 | 20892 | -0.181 | -0.2535 | Yes |
| 156 | Dut | 20934 | -0.182 | -0.2477 | Yes |
| 157 | Plk4 | 20993 | -0.184 | -0.2424 | Yes |
| 158 | Ddx39a | 21022 | -0.185 | -0.2359 | Yes |
| 159 | Rrm2 | 21094 | -0.187 | -0.2310 | Yes |
| 160 | Cdk1 | 21145 | -0.189 | -0.2252 | Yes |
| 161 | Ing3 | 21176 | -0.190 | -0.2186 | Yes |
| 162 | Jpt1 | 21311 | -0.195 | -0.2156 | Yes |
| 163 | Trip13 | 21406 | -0.198 | -0.2110 | Yes |
| 164 | Lyar | 21502 | -0.202 | -0.2063 | Yes |
| 165 | Rad1 | 21503 | -0.202 | -0.1982 | Yes |
| 166 | Ssrp1 | 21529 | -0.203 | -0.1909 | Yes |
| 167 | Spc25 | 21622 | -0.207 | -0.1859 | Yes |
| 168 | Eif2s1 | 21754 | -0.211 | -0.1821 | Yes |
| 169 | Cks1b | 21779 | -0.212 | -0.1744 | Yes |
| 170 | Spc24 | 21901 | -0.218 | -0.1701 | Yes |
| 171 | Mad2l1 | 21980 | -0.222 | -0.1639 | Yes |
| 172 | Ak2 | 22072 | -0.224 | -0.1582 | Yes |
| 173 | Ccne1 | 22210 | -0.231 | -0.1539 | Yes |
| 174 | Stmn1 | 22264 | -0.232 | -0.1464 | Yes |
| 175 | Plk1 | 22414 | -0.238 | -0.1422 | Yes |
| 176 | Pa2g4 | 22441 | -0.240 | -0.1335 | Yes |
| 177 | Lsm8 | 22471 | -0.241 | -0.1248 | Yes |
| 178 | Racgap1 | 22550 | -0.245 | -0.1178 | Yes |
| 179 | Bub1b | 22573 | -0.246 | -0.1087 | Yes |
| 180 | Tfrc | 22691 | -0.250 | -0.1029 | Yes |
| 181 | Donson | 22754 | -0.253 | -0.0949 | Yes |
| 182 | Tipin | 22945 | -0.261 | -0.0913 | Yes |
| 183 | Tubg1 | 23093 | -0.269 | -0.0858 | Yes |
| 184 | Dck | 23171 | -0.273 | -0.0776 | Yes |
| 185 | Shmt1 | 23206 | -0.275 | -0.0677 | Yes |
| 186 | Nme1 | 23686 | -0.295 | -0.0733 | Yes |
| 187 | H2az1 | 23733 | -0.297 | -0.0630 | Yes |
| 188 | Ranbp1 | 24429 | -0.334 | -0.0748 | Yes |
| 189 | Cdkn3 | 24527 | -0.340 | -0.0646 | Yes |
| 190 | Pop7 | 24734 | -0.349 | -0.0580 | Yes |
| 191 | Mthfd2 | 25463 | -0.403 | -0.0683 | Yes |
| 192 | Srsf1 | 25527 | -0.409 | -0.0541 | Yes |
| 193 | Birc5 | 25590 | -0.416 | -0.0396 | Yes |
| 194 | Cdkn2a | 25854 | -0.438 | -0.0315 | Yes |
| 195 | Rad51c | 26366 | -0.495 | -0.0301 | Yes |
| 196 | Ran | 26832 | -0.570 | -0.0241 | Yes |
| 197 | Cdkn1a | 27081 | -0.628 | -0.0077 | Yes |
| 198 | Hmga1b | 27210 | -0.662 | 0.0143 | Yes |

