Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	HSC.HSC_Pheno.cls#Group6_versus_Group8.HSC_Pheno.cls#Group6_versus_Group8_repos
Phenotype	HSC_Pheno.cls#Group6_versus_Group8_repos
Upregulated in class	5
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.19050065
Normalized Enrichment Score (NES)	-0.81760633
Nominal p-value	0.8504464
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Arhgdia	311	0.689	0.0034	No
2	Dusp3	323	0.683	0.0310	No
3	Grb2	450	0.624	0.0467	No
4	Pten	451	0.623	0.0727	No
5	Lck	1041	0.487	0.0451	No
6	Ralb	1067	0.482	0.0632	No
7	Arf1	1094	0.477	0.0810	No
8	Cab39l	1343	0.438	0.0790	No
9	Calr	1459	0.420	0.0871	No
10	Prkaa2	1721	0.386	0.0820	No
11	Rptor	1733	0.385	0.0971	No
12	Pin1	1981	0.354	0.0918	No
13	Prkar2a	2018	0.351	0.1035	No
14	Gsk3b	2036	0.350	0.1167	No
15	Ppp1ca	2063	0.346	0.1290	No
16	Eif4e	2136	0.339	0.1373	No
17	Prkag1	2222	0.330	0.1441	No
18	Trib3	2354	0.318	0.1467	No
19	Ppp2r1b	2472	0.305	0.1499	No
20	Pikfyve	2827	0.270	0.1323	No
21	Akt1	2864	0.265	0.1405	No
22	Tbk1	3486	0.215	0.0988	No
23	Ube2n	3593	0.205	0.0988	No
24	Nfkbib	3608	0.204	0.1061	No
25	Plcg1	3844	0.185	0.0947	No
26	Mknk1	3978	0.173	0.0910	No
27	Tsc2	3986	0.172	0.0976	No
28	Mknk2	4081	0.164	0.0968	No
29	Rps6ka1	4295	0.149	0.0857	No
30	Plcb1	4452	0.136	0.0787	No
31	Atf1	4570	0.128	0.0745	No
32	E2f1	4616	0.124	0.0760	No
33	Itpr2	4710	0.116	0.0732	No
34	Vav3	4823	0.107	0.0686	No
35	Ywhab	4862	0.105	0.0699	No
36	Actr2	4887	0.102	0.0722	No
37	Raf1	4957	0.098	0.0706	No
38	Hsp90b1	5716	0.041	0.0106	No
39	Irak4	5752	0.038	0.0093	No
40	Ptpn11	6032	0.018	-0.0127	No
41	Pak4	6073	0.014	-0.0154	No
42	Mapkap1	6158	0.006	-0.0220	No
43	Mapk9	6414	-0.005	-0.0425	No
44	Gna14	6656	-0.021	-0.0613	No
45	Dapp1	6820	-0.034	-0.0732	No
46	Acaca	6893	-0.039	-0.0774	No
47	Cltc	6908	-0.040	-0.0769	No
48	Grk2	6963	-0.045	-0.0794	No
49	Mapk1	7066	-0.052	-0.0855	No
50	Nod1	7067	-0.052	-0.0834	No
51	Actr3	7251	-0.066	-0.0955	No
52	Rac1	7266	-0.067	-0.0939	No
53	Ddit3	7319	-0.070	-0.0952	No
54	Map3k7	7382	-0.075	-0.0971	No
55	Arpc3	7414	-0.077	-0.0965	No
56	Tiam1	7436	-0.078	-0.0949	No
57	Prkcb	7838	-0.106	-0.1231	No
58	Il2rg	7891	-0.111	-0.1228	No
59	Csnk2b	7954	-0.117	-0.1229	No
60	Rit1	8198	-0.136	-0.1371	No
61	Them4	8466	-0.156	-0.1523	No
62	Slc2a1	8688	-0.173	-0.1631	No
63	Map2k6	8840	-0.186	-0.1676	No
64	Stat2	8904	-0.192	-0.1648	No
65	Cdk2	8956	-0.196	-0.1607	No
66	Ap2m1	9035	-0.204	-0.1586	No
67	Sla	9109	-0.211	-0.1557	No
68	Smad2	9425	-0.239	-0.1715	No
69	Sqstm1	9431	-0.239	-0.1619	No
70	Nck1	9642	-0.255	-0.1684	No
71	Akt1s1	9715	-0.262	-0.1633	No
72	Tnfrsf1a	9851	-0.272	-0.1630	No
73	Cxcr4	9960	-0.281	-0.1600	No
74	Mapk8	9975	-0.282	-0.1494	No
75	Ecsit	10062	-0.288	-0.1444	No
76	Pdk1	10094	-0.291	-0.1348	No
77	Pla2g12a	10728	-0.358	-0.1714	No
78	Cdk1	10963	-0.390	-0.1742	Yes
79	Ube2d3	11154	-0.414	-0.1725	Yes
80	Cfl1	11311	-0.445	-0.1666	Yes
81	Myd88	11356	-0.455	-0.1512	Yes
82	Il4	11490	-0.477	-0.1421	Yes
83	Rps6ka3	11803	-0.552	-0.1445	Yes
84	Traf2	11808	-0.553	-0.1218	Yes
85	Cab39	11828	-0.560	-0.1000	Yes
86	Cdkn1b	11845	-0.564	-0.0778	Yes
87	Ripk1	11881	-0.578	-0.0565	Yes
88	Pfn1	12055	-0.646	-0.0436	Yes
89	Map2k3	12142	-0.699	-0.0215	Yes
90	Cdk4	12313	-0.945	0.0041	Yes