Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | HSC.HSC_Pheno.cls#Group6_versus_Group8.HSC_Pheno.cls#Group6_versus_Group8_repos |
| Phenotype | HSC_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_IL6_JAK_STAT3_SIGNALING |
| Enrichment Score (ES) | -0.35920754 |
| Normalized Enrichment Score (NES) | -1.3133246 |
| Nominal p-value | 0.12688172 |
| FDR q-value | 0.64904416 |
| FWER p-Value | 0.69 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Tnfrsf1b | 177 | 0.779 | 0.0297 | No |
| 2 | Grb2 | 450 | 0.624 | 0.0430 | No |
| 3 | Bak1 | 795 | 0.534 | 0.0452 | No |
| 4 | Cd44 | 900 | 0.515 | 0.0659 | No |
| 5 | Il10rb | 986 | 0.496 | 0.0871 | No |
| 6 | Ifngr1 | 1461 | 0.419 | 0.0723 | No |
| 7 | Hax1 | 1824 | 0.372 | 0.0640 | No |
| 8 | Irf9 | 1892 | 0.363 | 0.0791 | No |
| 9 | Tlr2 | 2028 | 0.350 | 0.0879 | No |
| 10 | Csf1 | 2076 | 0.344 | 0.1036 | No |
| 11 | Ltbr | 2268 | 0.326 | 0.1065 | No |
| 12 | Pdgfc | 2810 | 0.272 | 0.0779 | No |
| 13 | Il17ra | 3250 | 0.233 | 0.0555 | No |
| 14 | Il7 | 4150 | 0.158 | -0.0086 | No |
| 15 | Jun | 4681 | 0.118 | -0.0450 | No |
| 16 | Csf2ra | 5432 | 0.063 | -0.1024 | No |
| 17 | Pim1 | 5494 | 0.058 | -0.1041 | No |
| 18 | Ltb | 5830 | 0.032 | -0.1295 | No |
| 19 | Il3ra | 5942 | 0.024 | -0.1371 | No |
| 20 | Ptpn11 | 6032 | 0.018 | -0.1434 | No |
| 21 | Csf3r | 6226 | 0.002 | -0.1589 | No |
| 22 | Socs1 | 6299 | 0.000 | -0.1648 | No |
| 23 | Osmr | 6352 | -0.000 | -0.1690 | No |
| 24 | Il15ra | 6748 | -0.027 | -0.1995 | No |
| 25 | Irf1 | 7030 | -0.049 | -0.2196 | No |
| 26 | Il18r1 | 7191 | -0.061 | -0.2291 | No |
| 27 | Ifnar1 | 7627 | -0.091 | -0.2593 | No |
| 28 | Stat1 | 7703 | -0.096 | -0.2599 | No |
| 29 | Il2rg | 7891 | -0.111 | -0.2689 | No |
| 30 | Acvr1b | 8669 | -0.172 | -0.3223 | No |
| 31 | Ebi3 | 8714 | -0.175 | -0.3160 | No |
| 32 | Il4ra | 8882 | -0.190 | -0.3188 | No |
| 33 | Stat2 | 8904 | -0.192 | -0.3096 | No |
| 34 | Ifngr2 | 9515 | -0.248 | -0.3452 | Yes |
| 35 | Fas | 9669 | -0.258 | -0.3430 | Yes |
| 36 | Itgb3 | 9755 | -0.265 | -0.3349 | Yes |
| 37 | Tnfrsf1a | 9851 | -0.272 | -0.3272 | Yes |
| 38 | Il1r1 | 9919 | -0.278 | -0.3170 | Yes |
| 39 | Crlf2 | 9995 | -0.284 | -0.3070 | Yes |
| 40 | Stat3 | 10008 | -0.286 | -0.2917 | Yes |
| 41 | Itga4 | 10252 | -0.307 | -0.2941 | Yes |
| 42 | Cbl | 10395 | -0.322 | -0.2874 | Yes |
| 43 | Tyk2 | 10421 | -0.323 | -0.2712 | Yes |
| 44 | Il6st | 10684 | -0.353 | -0.2724 | Yes |
| 45 | Map3k8 | 10924 | -0.384 | -0.2701 | Yes |
| 46 | Ptpn1 | 11044 | -0.398 | -0.2573 | Yes |
| 47 | Il12rb1 | 11289 | -0.438 | -0.2523 | Yes |
| 48 | Myd88 | 11356 | -0.455 | -0.2319 | Yes |
| 49 | Pik3r5 | 11375 | -0.457 | -0.2075 | Yes |
| 50 | Socs3 | 11693 | -0.521 | -0.2037 | Yes |
| 51 | Tnfrsf21 | 11779 | -0.544 | -0.1798 | Yes |
| 52 | Stam2 | 11925 | -0.591 | -0.1582 | Yes |
| 53 | Cd38 | 12171 | -0.719 | -0.1373 | Yes |
| 54 | Tgfb1 | 12274 | -0.840 | -0.0981 | Yes |
| 55 | Ptpn2 | 12306 | -0.925 | -0.0482 | Yes |
| 56 | Cd9 | 12308 | -0.932 | 0.0045 | Yes |
