| Dataset | HSC.HSC_Pheno.cls#Group6_versus_Group8.HSC_Pheno.cls#Group6_versus_Group8_repos |
| Phenotype | HSC_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | -0.31680527 |
| Normalized Enrichment Score (NES) | -0.94930655 |
| Nominal p-value | 0.61318684 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Mcm5 | 146 | 0.814 | 0.0043 | No |
| 2 | Gspt1 | 210 | 0.755 | 0.0143 | No |
| 3 | Pa2g4 | 276 | 0.707 | 0.0231 | No |
| 4 | Ppp1r8 | 342 | 0.671 | 0.0312 | No |
| 5 | Mre11a | 512 | 0.603 | 0.0294 | No |
| 6 | Nup153 | 535 | 0.598 | 0.0395 | No |
| 7 | Tfrc | 597 | 0.579 | 0.0461 | No |
| 8 | Rad1 | 696 | 0.556 | 0.0492 | No |
| 9 | Ube2s | 800 | 0.532 | 0.0514 | No |
| 10 | H2az1 | 823 | 0.529 | 0.0602 | No |
| 11 | Psmc3ip | 873 | 0.519 | 0.0665 | No |
| 12 | Gins4 | 911 | 0.514 | 0.0738 | No |
| 13 | Ran | 984 | 0.497 | 0.0778 | No |
| 14 | Asf1a | 993 | 0.495 | 0.0871 | No |
| 15 | Dctpp1 | 1186 | 0.462 | 0.0806 | No |
| 16 | Nolc1 | 1266 | 0.448 | 0.0830 | No |
| 17 | Snrpb | 1648 | 0.396 | 0.0597 | No |
| 18 | Srsf2 | 1684 | 0.390 | 0.0646 | No |
| 19 | Tra2b | 1702 | 0.389 | 0.0710 | No |
| 20 | Prps1 | 1715 | 0.387 | 0.0778 | No |
| 21 | Mcm3 | 1796 | 0.376 | 0.0787 | No |
| 22 | Chek1 | 1833 | 0.370 | 0.0832 | No |
| 23 | Lsm8 | 1879 | 0.365 | 0.0868 | No |
| 24 | Wdr90 | 1891 | 0.363 | 0.0931 | No |
| 25 | Timeless | 1941 | 0.360 | 0.0963 | No |
| 26 | Mlh1 | 2227 | 0.330 | 0.0795 | No |
| 27 | Ccp110 | 2234 | 0.329 | 0.0856 | No |
| 28 | Srsf1 | 2325 | 0.321 | 0.0847 | No |
| 29 | Rpa3 | 2355 | 0.318 | 0.0886 | No |
| 30 | Trp53 | 2438 | 0.309 | 0.0881 | No |
| 31 | Nudt21 | 2877 | 0.264 | 0.0574 | No |
| 32 | Pold1 | 2933 | 0.260 | 0.0581 | No |
| 33 | Pole4 | 3151 | 0.244 | 0.0452 | No |
| 34 | Dut | 3277 | 0.230 | 0.0395 | No |
| 35 | Nap1l1 | 3308 | 0.228 | 0.0416 | No |
| 36 | Cenpm | 3403 | 0.221 | 0.0383 | No |
| 37 | Dnmt1 | 3708 | 0.197 | 0.0173 | No |
| 38 | Tubg1 | 3755 | 0.192 | 0.0174 | No |
| 39 | Tacc3 | 3955 | 0.175 | 0.0046 | No |
| 40 | Ilf3 | 4003 | 0.171 | 0.0041 | No |
| 41 | Pold3 | 4019 | 0.169 | 0.0063 | No |
| 42 | Spc25 | 4051 | 0.166 | 0.0071 | No |
| 43 | Smc1a | 4076 | 0.164 | 0.0084 | No |
| 44 | Mcm6 | 4288 | 0.150 | -0.0059 | No |
| 45 | Chek2 | 4320 | 0.147 | -0.0055 | No |
| 46 | Lbr | 4340 | 0.146 | -0.0042 | No |
| 47 | Brca1 | 4372 | 0.143 | -0.0039 | No |
| 48 | E2f8 | 4378 | 0.143 | -0.0014 | No |
| 49 | Mcm7 | 4407 | 0.140 | -0.0009 | No |
| 50 | Mcm4 | 4523 | 0.131 | -0.0077 | No |
| 51 | Exosc8 | 4580 | 0.126 | -0.0098 | No |
| 52 | Rfc1 | 4772 | 0.111 | -0.0232 | No |
| 53 | Nup205 | 4774 | 0.111 | -0.0211 | No |
| 54 | Pcna | 4909 | 0.101 | -0.0301 | No |
| 55 | Pold2 | 4946 | 0.099 | -0.0311 | No |
| 56 | Brms1l | 5011 | 0.093 | -0.0345 | No |
| 57 | Nop56 | 5076 | 0.088 | -0.0379 | No |
| 58 | Phf5a | 5232 | 0.078 | -0.0491 | No |
| 59 | Myc | 5245 | 0.078 | -0.0485 | No |
| 60 | Eed | 5371 | 0.067 | -0.0574 | No |
| 61 | Rrm2 | 5374 | 0.067 | -0.0563 | No |
| 62 | Mms22l | 5388 | 0.065 | -0.0560 | No |
| 63 | Anp32e | 5547 | 0.053 | -0.0679 | No |
| 64 | Rad50 | 5579 | 0.051 | -0.0695 | No |
| 65 | Shmt1 | 5603 | 0.049 | -0.0704 | No |
| 66 | Plk4 | 5676 | 0.044 | -0.0754 | No |
| 67 | Rpa1 | 5745 | 0.038 | -0.0802 | No |
| 68 | Pan2 | 5755 | 0.038 | -0.0802 | No |
| 69 | Lyar | 5771 | 0.036 | -0.0807 | No |
| 70 | Lmnb1 | 5780 | 0.035 | -0.0807 | No |
| 71 | Smc3 | 5797 | 0.034 | -0.0813 | No |
| 72 | Nbn | 5916 | 0.026 | -0.0905 | No |
| 73 | Nme1 | 5973 | 0.022 | -0.0946 | No |
| 74 | Atad2 | 6009 | 0.019 | -0.0971 | No |
| 75 | Usp1 | 6047 | 0.016 | -0.0998 | No |
| 76 | Zw10 | 6054 | 0.015 | -0.1000 | No |
| 77 | Bard1 | 6086 | 0.012 | -0.1023 | No |
| 78 | Xpo1 | 6098 | 0.011 | -0.1030 | No |
| 79 | Rpa2 | 6102 | 0.011 | -0.1030 | No |
| 80 | Cnot9 | 6127 | 0.008 | -0.1048 | No |
| 81 | Mybl2 | 6141 | 0.007 | -0.1058 | No |
| 82 | Nup107 | 6172 | 0.006 | -0.1081 | No |
| 83 | Orc6 | 6231 | 0.002 | -0.1128 | No |
| 84 | Pms2 | 6255 | 0.000 | -0.1147 | No |
| 85 | Birc5 | 6270 | 0.000 | -0.1159 | No |
| 86 | Mcm2 | 6448 | -0.008 | -0.1302 | No |
| 87 | Ccne1 | 6515 | -0.012 | -0.1354 | No |
| 88 | H2ax | 6571 | -0.015 | -0.1396 | No |
| 89 | Hells | 6700 | -0.025 | -0.1496 | No |
| 90 | Suv39h1 | 6817 | -0.033 | -0.1585 | No |
| 91 | Xrcc6 | 6949 | -0.043 | -0.1684 | No |
| 92 | Mthfd2 | 6966 | -0.045 | -0.1688 | No |
| 93 | Hnrnpd | 7095 | -0.054 | -0.1782 | No |
| 94 | Eif2s1 | 7116 | -0.056 | -0.1787 | No |
| 95 | Hmgb3 | 7122 | -0.057 | -0.1780 | No |
| 96 | Brca2 | 7265 | -0.067 | -0.1883 | No |
| 97 | Rnaseh2a | 7268 | -0.067 | -0.1872 | No |
| 98 | Dclre1b | 7316 | -0.070 | -0.1896 | No |
| 99 | Ppm1d | 7403 | -0.076 | -0.1952 | No |
| 100 | Rbbp7 | 7479 | -0.082 | -0.1997 | No |
| 101 | Dscc1 | 7508 | -0.084 | -0.2003 | No |
| 102 | Pds5b | 7565 | -0.087 | -0.2031 | No |
| 103 | Prkdc | 7578 | -0.088 | -0.2024 | No |
| 104 | Ccnb2 | 7609 | -0.090 | -0.2030 | No |
| 105 | Stmn1 | 7655 | -0.093 | -0.2049 | No |
| 106 | Hus1 | 7665 | -0.093 | -0.2037 | No |
| 107 | Gins1 | 7762 | -0.101 | -0.2096 | No |
| 108 | Ube2t | 7855 | -0.108 | -0.2150 | No |
| 109 | Tipin | 8029 | -0.123 | -0.2267 | No |
| 110 | Orc2 | 8061 | -0.126 | -0.2268 | No |
| 111 | Smc4 | 8266 | -0.141 | -0.2407 | No |
| 112 | Lig1 | 8352 | -0.147 | -0.2447 | No |
| 113 | Tbrg4 | 8413 | -0.152 | -0.2466 | No |
| 114 | Ipo7 | 8679 | -0.173 | -0.2649 | No |
| 115 | Donson | 8746 | -0.177 | -0.2667 | No |
| 116 | Nasp | 8787 | -0.182 | -0.2664 | No |
| 117 | Mki67 | 8838 | -0.186 | -0.2668 | No |
| 118 | Cbx5 | 8842 | -0.187 | -0.2633 | No |
| 119 | Tmpo | 8865 | -0.188 | -0.2613 | No |
| 120 | Rfc3 | 8879 | -0.189 | -0.2586 | No |
| 121 | Mad2l1 | 8929 | -0.194 | -0.2587 | No |
| 122 | Pnn | 9108 | -0.211 | -0.2691 | No |
| 123 | Aurka | 9180 | -0.217 | -0.2706 | No |
| 124 | Spag5 | 9335 | -0.230 | -0.2786 | No |
| 125 | Top2a | 9408 | -0.237 | -0.2798 | No |
| 126 | Wee1 | 9460 | -0.242 | -0.2791 | No |
| 127 | Ranbp1 | 9502 | -0.247 | -0.2776 | No |
| 128 | Cit | 9525 | -0.248 | -0.2744 | No |
| 129 | Smc6 | 9986 | -0.283 | -0.3065 | No |
| 130 | Paics | 10005 | -0.286 | -0.3023 | No |
| 131 | Dck | 10164 | -0.297 | -0.3093 | No |
| 132 | Pola2 | 10254 | -0.307 | -0.3104 | Yes |
| 133 | Rad51ap1 | 10313 | -0.313 | -0.3089 | Yes |
| 134 | Kif18b | 10410 | -0.322 | -0.3104 | Yes |
| 135 | Pttg1 | 10440 | -0.326 | -0.3062 | Yes |
| 136 | Dek | 10523 | -0.336 | -0.3062 | Yes |
| 137 | Stag1 | 10560 | -0.340 | -0.3024 | Yes |
| 138 | Jpt1 | 10568 | -0.342 | -0.2961 | Yes |
| 139 | Tubb5 | 10588 | -0.345 | -0.2907 | Yes |
| 140 | Ncapd2 | 10656 | -0.351 | -0.2892 | Yes |
| 141 | Ezh2 | 10690 | -0.354 | -0.2848 | Yes |
| 142 | Cdc20 | 10706 | -0.355 | -0.2790 | Yes |
| 143 | Cdkn2c | 10707 | -0.355 | -0.2719 | Yes |
| 144 | Msh2 | 10722 | -0.357 | -0.2659 | Yes |
| 145 | Luc7l3 | 10745 | -0.360 | -0.2605 | Yes |
| 146 | Depdc1a | 10852 | -0.375 | -0.2617 | Yes |
| 147 | Rad21 | 10858 | -0.375 | -0.2546 | Yes |
| 148 | Cks2 | 10907 | -0.382 | -0.2509 | Yes |
| 149 | Cdc25a | 10917 | -0.383 | -0.2439 | Yes |
| 150 | Cdk1 | 10963 | -0.390 | -0.2398 | Yes |
| 151 | Ak2 | 10968 | -0.390 | -0.2324 | Yes |
| 152 | Ctcf | 10983 | -0.392 | -0.2257 | Yes |
| 153 | Slbp | 11024 | -0.395 | -0.2210 | Yes |
| 154 | Cenpe | 11053 | -0.399 | -0.2153 | Yes |
| 155 | Dlgap5 | 11083 | -0.403 | -0.2097 | Yes |
| 156 | Prim2 | 11093 | -0.404 | -0.2023 | Yes |
| 157 | Tk1 | 11462 | -0.474 | -0.2230 | Yes |
| 158 | Diaph3 | 11602 | -0.501 | -0.2244 | Yes |
| 159 | Pole | 11613 | -0.502 | -0.2152 | Yes |
| 160 | Trip13 | 11681 | -0.516 | -0.2104 | Yes |
| 161 | Cdca8 | 11682 | -0.516 | -0.2000 | Yes |
| 162 | Psip1 | 11716 | -0.525 | -0.1922 | Yes |
| 163 | Cse1l | 11727 | -0.529 | -0.1825 | Yes |
| 164 | Racgap1 | 11801 | -0.551 | -0.1774 | Yes |
| 165 | Cdkn1b | 11845 | -0.564 | -0.1697 | Yes |
| 166 | Kif4 | 11849 | -0.566 | -0.1586 | Yes |
| 167 | Ubr7 | 11873 | -0.575 | -0.1490 | Yes |
| 168 | Prdx4 | 11875 | -0.576 | -0.1375 | Yes |
| 169 | Ddx39a | 11964 | -0.604 | -0.1327 | Yes |
| 170 | Hmgb2 | 11974 | -0.608 | -0.1212 | Yes |
| 171 | Cdc25b | 11976 | -0.609 | -0.1091 | Yes |
| 172 | Bub1b | 11980 | -0.609 | -0.0972 | Yes |
| 173 | Ssrp1 | 12067 | -0.652 | -0.0912 | Yes |
| 174 | Gins3 | 12123 | -0.689 | -0.0820 | Yes |
| 175 | Hmmr | 12133 | -0.694 | -0.0688 | Yes |
| 176 | Rfc2 | 12224 | -0.766 | -0.0608 | Yes |
| 177 | Cdk4 | 12313 | -0.945 | -0.0492 | Yes |
| 178 | Syncrip | 12329 | -1.024 | -0.0299 | Yes |
| 179 | Ing3 | 12363 | -1.630 | -0.0000 | Yes |

