| Dataset | HSC.HSC_Pheno.cls#Group6_versus_Group8.HSC_Pheno.cls#Group6_versus_Group8_repos |
| Phenotype | HSC_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_DNA_REPAIR |
| Enrichment Score (ES) | -0.20898502 |
| Normalized Enrichment Score (NES) | -0.935645 |
| Nominal p-value | 0.5828221 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Polr3gl | 49 | 0.979 | 0.0176 | No |
| 2 | Cant1 | 98 | 0.876 | 0.0330 | No |
| 3 | Tk2 | 117 | 0.853 | 0.0503 | No |
| 4 | Pom121 | 138 | 0.821 | 0.0668 | No |
| 5 | Ddb2 | 147 | 0.812 | 0.0841 | No |
| 6 | Gmpr2 | 164 | 0.791 | 0.1002 | No |
| 7 | Rev3l | 171 | 0.785 | 0.1170 | No |
| 8 | Rfc5 | 189 | 0.765 | 0.1325 | No |
| 9 | Polr2e | 291 | 0.700 | 0.1397 | No |
| 10 | Nme4 | 365 | 0.663 | 0.1483 | No |
| 11 | Mpg | 416 | 0.640 | 0.1584 | No |
| 12 | Pnp | 619 | 0.574 | 0.1545 | No |
| 13 | Rad52 | 660 | 0.564 | 0.1637 | No |
| 14 | Dgcr8 | 785 | 0.536 | 0.1654 | No |
| 15 | Alyref | 829 | 0.528 | 0.1735 | No |
| 16 | Ercc2 | 981 | 0.498 | 0.1721 | No |
| 17 | Gtf2h5 | 1051 | 0.486 | 0.1772 | No |
| 18 | Zfp707 | 1082 | 0.479 | 0.1853 | No |
| 19 | Taf9 | 1086 | 0.479 | 0.1956 | No |
| 20 | Impdh2 | 1174 | 0.464 | 0.1988 | No |
| 21 | Rnmt | 1405 | 0.427 | 0.1894 | No |
| 22 | Gtf2h3 | 1486 | 0.415 | 0.1920 | No |
| 23 | Stx3 | 1642 | 0.397 | 0.1880 | No |
| 24 | Tsg101 | 1696 | 0.389 | 0.1923 | No |
| 25 | Aprt | 1724 | 0.386 | 0.1986 | No |
| 26 | Taf6 | 1877 | 0.365 | 0.1942 | No |
| 27 | Ncbp2 | 2040 | 0.349 | 0.1886 | No |
| 28 | Rpa3 | 2355 | 0.318 | 0.1700 | No |
| 29 | Trp53 | 2438 | 0.309 | 0.1701 | No |
| 30 | Rala | 2858 | 0.266 | 0.1417 | No |
| 31 | Nudt21 | 2877 | 0.264 | 0.1460 | No |
| 32 | Poll | 2905 | 0.262 | 0.1496 | No |
| 33 | Gsdme | 2923 | 0.261 | 0.1540 | No |
| 34 | Ercc8 | 2928 | 0.260 | 0.1594 | No |
| 35 | Pold1 | 2933 | 0.260 | 0.1648 | No |
| 36 | Rbx1 | 3020 | 0.254 | 0.1634 | No |
| 37 | Polr2f | 3073 | 0.252 | 0.1647 | No |
| 38 | Pole4 | 3151 | 0.244 | 0.1638 | No |
| 39 | Brf2 | 3230 | 0.235 | 0.1626 | No |
| 40 | Dut | 3277 | 0.230 | 0.1639 | No |
| 41 | Gtf2f1 | 3282 | 0.230 | 0.1686 | No |
| 42 | Cetn2 | 3317 | 0.227 | 0.1708 | No |
| 43 | Polr1c | 3402 | 0.221 | 0.1688 | No |
| 44 | Sec61a1 | 3618 | 0.203 | 0.1557 | No |
| 45 | Polr1d | 3705 | 0.197 | 0.1531 | No |
| 46 | Ddb1 | 3732 | 0.195 | 0.1552 | No |
| 47 | Nfx1 | 3757 | 0.192 | 0.1575 | No |
| 48 | Pold3 | 4019 | 0.169 | 0.1399 | No |
| 49 | Polr2h | 4094 | 0.163 | 0.1374 | No |
| 50 | Cstf3 | 4165 | 0.156 | 0.1351 | No |
| 51 | Nt5c3 | 4321 | 0.147 | 0.1257 | No |
| 52 | Eif1b | 4472 | 0.134 | 0.1164 | No |
| 53 | Vps37d | 4487 | 0.134 | 0.1182 | No |
| 54 | Dguok | 4502 | 0.133 | 0.1200 | No |
| 55 | Tyms | 4545 | 0.129 | 0.1194 | No |
| 56 | Itpa | 4546 | 0.129 | 0.1222 | No |
| 57 | Sdcbp | 4609 | 0.124 | 0.1199 | No |
| 58 | Nelfb | 4634 | 0.122 | 0.1206 | No |
| 59 | Pcna | 4909 | 0.101 | 0.1004 | No |
| 60 | Npr2 | 5129 | 0.085 | 0.0844 | No |
| 61 | Bcap31 | 5865 | 0.030 | 0.0249 | No |
| 62 | Supt5 | 5875 | 0.029 | 0.0248 | No |
| 63 | Dad1 | 5888 | 0.028 | 0.0245 | No |
| 64 | Taf12 | 5969 | 0.022 | 0.0184 | No |
| 65 | Nme1 | 5973 | 0.022 | 0.0186 | No |
| 66 | Rpa2 | 6102 | 0.011 | 0.0084 | No |
| 67 | Taf10 | 6369 | -0.002 | -0.0133 | No |
| 68 | Hcls1 | 6398 | -0.003 | -0.0155 | No |
| 69 | Srsf6 | 6518 | -0.012 | -0.0250 | No |
| 70 | Ercc4 | 6544 | -0.013 | -0.0268 | No |
| 71 | Sf3a3 | 6618 | -0.019 | -0.0323 | No |
| 72 | Ada | 6634 | -0.020 | -0.0331 | No |
| 73 | Snapc5 | 6829 | -0.034 | -0.0482 | No |
| 74 | Ercc1 | 7007 | -0.048 | -0.0616 | No |
| 75 | Dctn4 | 7013 | -0.048 | -0.0610 | No |
| 76 | Ak1 | 7055 | -0.051 | -0.0632 | No |
| 77 | Edf1 | 7114 | -0.056 | -0.0667 | No |
| 78 | Polr2a | 7207 | -0.063 | -0.0728 | No |
| 79 | Gtf2b | 7281 | -0.067 | -0.0773 | No |
| 80 | Surf1 | 7306 | -0.069 | -0.0778 | No |
| 81 | Tarbp2 | 7584 | -0.089 | -0.0985 | No |
| 82 | Clp1 | 7923 | -0.114 | -0.1236 | No |
| 83 | Polh | 7956 | -0.117 | -0.1236 | No |
| 84 | Nelfe | 8231 | -0.139 | -0.1430 | No |
| 85 | Taf13 | 8233 | -0.139 | -0.1400 | No |
| 86 | Lig1 | 8352 | -0.147 | -0.1464 | No |
| 87 | Fen1 | 8381 | -0.149 | -0.1454 | No |
| 88 | Usp11 | 8423 | -0.153 | -0.1454 | No |
| 89 | Guk1 | 8433 | -0.153 | -0.1427 | No |
| 90 | Zwint | 8456 | -0.155 | -0.1411 | No |
| 91 | Smad5 | 8564 | -0.164 | -0.1463 | No |
| 92 | Ercc5 | 8622 | -0.168 | -0.1472 | No |
| 93 | Nelfcd | 8660 | -0.171 | -0.1464 | No |
| 94 | Eloa | 8661 | -0.171 | -0.1427 | No |
| 95 | Rfc3 | 8879 | -0.189 | -0.1562 | No |
| 96 | Rad51 | 9033 | -0.203 | -0.1643 | No |
| 97 | Rrm2b | 9394 | -0.235 | -0.1885 | No |
| 98 | Ell | 9519 | -0.248 | -0.1932 | No |
| 99 | Pola1 | 9520 | -0.248 | -0.1877 | No |
| 100 | Ercc3 | 9531 | -0.249 | -0.1831 | No |
| 101 | Nudt9 | 9616 | -0.254 | -0.1843 | No |
| 102 | Mrpl40 | 9803 | -0.268 | -0.1936 | No |
| 103 | Cox17 | 9889 | -0.275 | -0.1945 | No |
| 104 | Gtf2a2 | 9937 | -0.279 | -0.1922 | No |
| 105 | Gpx4 | 10021 | -0.287 | -0.1927 | No |
| 106 | Gtf2h1 | 10119 | -0.294 | -0.1941 | No |
| 107 | Gtf3c5 | 10172 | -0.298 | -0.1918 | No |
| 108 | Pola2 | 10254 | -0.307 | -0.1916 | No |
| 109 | Mpc2 | 10333 | -0.315 | -0.1911 | No |
| 110 | Ak3 | 10425 | -0.324 | -0.1914 | No |
| 111 | Ago4 | 10457 | -0.328 | -0.1867 | No |
| 112 | Vps37b | 10471 | -0.330 | -0.1805 | No |
| 113 | Snapc4 | 10755 | -0.362 | -0.1956 | No |
| 114 | Aaas | 10780 | -0.366 | -0.1895 | No |
| 115 | Vps28 | 11019 | -0.395 | -0.2003 | Yes |
| 116 | Upf3b | 11025 | -0.395 | -0.1920 | Yes |
| 117 | Rae1 | 11100 | -0.405 | -0.1891 | Yes |
| 118 | Cmpk2 | 11162 | -0.415 | -0.1849 | Yes |
| 119 | Nt5c | 11236 | -0.428 | -0.1814 | Yes |
| 120 | Prim1 | 11371 | -0.457 | -0.1823 | Yes |
| 121 | Polr2c | 11432 | -0.470 | -0.1769 | Yes |
| 122 | Taf1c | 11438 | -0.471 | -0.1669 | Yes |
| 123 | Supt4a | 11461 | -0.474 | -0.1582 | Yes |
| 124 | Adrm1 | 11466 | -0.474 | -0.1481 | Yes |
| 125 | Polr1h | 11530 | -0.484 | -0.1426 | Yes |
| 126 | Umps | 11603 | -0.501 | -0.1374 | Yes |
| 127 | Rfc4 | 11617 | -0.503 | -0.1274 | Yes |
| 128 | Bcam | 11670 | -0.513 | -0.1203 | Yes |
| 129 | Adcy6 | 11713 | -0.524 | -0.1122 | Yes |
| 130 | Arl6ip1 | 11761 | -0.537 | -0.1042 | Yes |
| 131 | Polb | 11767 | -0.540 | -0.0927 | Yes |
| 132 | Polr2g | 12009 | -0.617 | -0.0988 | Yes |
| 133 | Pold4 | 12019 | -0.621 | -0.0858 | Yes |
| 134 | Ssrp1 | 12067 | -0.652 | -0.0753 | Yes |
| 135 | Rfc2 | 12224 | -0.766 | -0.0711 | Yes |
| 136 | Xpc | 12251 | -0.795 | -0.0557 | Yes |
| 137 | Polr3c | 12315 | -0.945 | -0.0400 | Yes |
| 138 | Polr2j | 12322 | -0.987 | -0.0188 | Yes |
| 139 | Pde4b | 12325 | -0.999 | 0.0031 | Yes |

