Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	HSC.HSC_Pheno.cls#Group3_versus_Group4.HSC_Pheno.cls#Group3_versus_Group4_repos
Phenotype	HSC_Pheno.cls#Group3_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.24486181
Normalized Enrichment Score (NES)	-1.0485612
Nominal p-value	0.3838384
FDR q-value	0.886895
FWER p-Value	0.992

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Rchy1	41	0.993	0.0197	No
2	Tgfb1	215	0.719	0.0223	No
3	Ctsf	380	0.641	0.0238	No
4	Ctsd	496	0.596	0.0282	No
5	Abat	574	0.577	0.0353	No
6	Baiap2	586	0.573	0.0478	No
7	Ccnd2	881	0.508	0.0355	No
8	Dram1	902	0.502	0.0455	No
9	Rrp8	918	0.499	0.0559	No
10	Cyfip2	1064	0.474	0.0551	No
11	Ccnk	1272	0.444	0.0485	No
12	Gm2a	1314	0.439	0.0553	No
13	Retsat	1318	0.439	0.0653	No
14	Pitpnc1	1319	0.439	0.0755	No
15	F2r	1541	0.409	0.0669	No
16	Dcxr	1553	0.407	0.0755	No
17	Pcna	1566	0.406	0.0839	No
18	Rhbdf2	1642	0.397	0.0870	No
19	Sesn1	1763	0.380	0.0860	No
20	Trp53	1912	0.360	0.0823	No
21	Dgka	1916	0.360	0.0904	No
22	Ddb2	1946	0.358	0.0963	No
23	Plxnb2	1969	0.354	0.1028	No
24	Tob1	2012	0.350	0.1075	No
25	Slc35d1	2031	0.348	0.1141	No
26	Casp1	2057	0.346	0.1201	No
27	Zfp36l1	2191	0.332	0.1169	No
28	Ldhb	2193	0.331	0.1246	No
29	S100a10	2248	0.326	0.1277	No
30	Fbxw7	2273	0.323	0.1333	No
31	Mapkapk3	2277	0.323	0.1405	No
32	Ier5	2322	0.319	0.1443	No
33	Ier3	2453	0.305	0.1408	No
34	Ccp110	2673	0.288	0.1296	No
35	Hdac3	2807	0.279	0.1252	No
36	Csrnp2	2847	0.276	0.1284	No
37	Ndrg1	2885	0.273	0.1317	No
38	Acvr1b	2969	0.264	0.1311	No
39	Stom	3076	0.258	0.1284	No
40	Ptpre	3086	0.257	0.1336	No
41	H1f2	3187	0.249	0.1312	No
42	St14	3285	0.239	0.1288	No
43	Ddit4	3381	0.232	0.1264	No
44	Zmat3	3444	0.225	0.1266	No
45	Klf4	3635	0.209	0.1159	No
46	Irak1	3873	0.194	0.1010	No
47	Iscu	3942	0.189	0.0998	No
48	App	4019	0.183	0.0978	No
49	Kif13b	4183	0.171	0.0885	No
50	Bax	4302	0.161	0.0825	No
51	Abcc5	4327	0.160	0.0843	No
52	Trib3	4407	0.153	0.0814	No
53	Vamp8	4421	0.152	0.0839	No
54	Ccng1	4473	0.149	0.0832	No
55	Prmt2	4740	0.130	0.0644	No
56	Blcap	4869	0.122	0.0567	No
57	Pidd1	5023	0.111	0.0468	No
58	H2aj	5064	0.109	0.0461	No
59	Klk8	5089	0.107	0.0466	No
60	Abhd4	5153	0.102	0.0438	No
61	Hint1	5213	0.098	0.0412	No
62	Trafd1	5323	0.090	0.0344	No
63	Mdm2	5441	0.081	0.0267	No
64	Rxra	5448	0.081	0.0281	No
65	Vwa5a	5482	0.079	0.0272	No
66	Def6	5531	0.076	0.0250	No
67	Ercc5	5751	0.059	0.0085	No
68	Fuca1	5767	0.058	0.0086	No
69	Zbtb16	5793	0.056	0.0079	No
70	Ninj1	5835	0.052	0.0057	No
71	Rab40c	5893	0.049	0.0022	No
72	Ralgds	6136	0.035	-0.0168	No
73	Prkab1	6145	0.034	-0.0167	No
74	Osgin1	6326	0.021	-0.0309	No
75	Rps12	6765	-0.001	-0.0668	No
76	Tcn2	6789	-0.003	-0.0686	No
77	Tprkb	6847	-0.007	-0.0731	No
78	Mxd4	6857	-0.008	-0.0736	No
79	Pmm1	7028	-0.021	-0.0871	No
80	Rb1	7093	-0.024	-0.0918	No
81	Mknk2	7215	-0.032	-0.1009	No
82	Fam162a	7225	-0.033	-0.1009	No
83	Sertad3	7266	-0.037	-0.1033	No
84	Pvt1	7340	-0.041	-0.1084	No
85	Wwp1	7389	-0.046	-0.1112	No
86	Upp1	7390	-0.046	-0.1102	No
87	Nol8	7525	-0.055	-0.1198	No
88	Rad9a	7563	-0.058	-0.1215	No
89	Hspa4l	7629	-0.062	-0.1254	No
90	Tap1	7723	-0.069	-0.1314	No
91	Fgf13	7806	-0.076	-0.1364	No
92	Tm4sf1	7812	-0.076	-0.1350	No
93	Pom121	7850	-0.079	-0.1362	No
94	Ppp1r15a	8160	-0.103	-0.1591	No
95	Socs1	8290	-0.113	-0.1671	No
96	Steap3	8318	-0.115	-0.1666	No
97	Vdr	8329	-0.116	-0.1647	No
98	Ei24	8582	-0.136	-0.1822	No
99	Foxo3	8682	-0.145	-0.1869	No
100	Cgrrf1	8720	-0.148	-0.1865	No
101	Sec61a1	8752	-0.151	-0.1855	No
102	Txnip	8832	-0.160	-0.1883	No
103	Elp1	8902	-0.164	-0.1901	No
104	Apaf1	8960	-0.169	-0.1909	No
105	Bak1	8988	-0.171	-0.1891	No
106	Aen	9047	-0.174	-0.1898	No
107	Cdkn2aip	9051	-0.174	-0.1860	No
108	Ephx1	9069	-0.176	-0.1833	No
109	Btg1	9195	-0.188	-0.1892	No
110	Tspyl2	9371	-0.200	-0.1989	No
111	Slc3a2	9421	-0.205	-0.1981	No
112	Hexim1	9474	-0.210	-0.1975	No
113	Mxd1	9859	-0.246	-0.2232	No
114	Ptpn14	9899	-0.250	-0.2206	No
115	Wrap73	9970	-0.258	-0.2203	No
116	Jag2	10067	-0.265	-0.2220	No
117	Cd81	10111	-0.268	-0.2193	No
118	Polh	10192	-0.276	-0.2194	No
119	Sp1	10303	-0.288	-0.2218	No
120	Tpd52l1	10586	-0.319	-0.2374	Yes
121	Eps8l2	10611	-0.322	-0.2319	Yes
122	Fos	10616	-0.322	-0.2248	Yes
123	Tsc22d1	10629	-0.324	-0.2182	Yes
124	Jun	10678	-0.331	-0.2144	Yes
125	Notch1	10721	-0.337	-0.2101	Yes
126	Cd82	10773	-0.344	-0.2062	Yes
127	Plk2	10803	-0.349	-0.2005	Yes
128	Ppm1d	10811	-0.350	-0.1929	Yes
129	Rnf19b	10891	-0.360	-0.1910	Yes
130	Ccnd3	11006	-0.377	-0.1916	Yes
131	Hbegf	11120	-0.393	-0.1917	Yes
132	Rack1	11259	-0.411	-0.1934	Yes
133	Sat1	11297	-0.417	-0.1868	Yes
134	Tm7sf3	11304	-0.418	-0.1775	Yes
135	Fdxr	11308	-0.419	-0.1680	Yes
136	Ip6k2	11341	-0.423	-0.1608	Yes
137	Tgfa	11446	-0.440	-0.1591	Yes
138	Rap2b	11526	-0.456	-0.1550	Yes
139	Slc19a2	11576	-0.465	-0.1482	Yes
140	Ddit3	11617	-0.474	-0.1404	Yes
141	Ak1	11625	-0.477	-0.1299	Yes
142	H2ac25	11639	-0.479	-0.1198	Yes
143	Fas	11642	-0.481	-0.1088	Yes
144	Rpl18	11656	-0.483	-0.0986	Yes
145	Ada	11664	-0.485	-0.0879	Yes
146	Irag2	11685	-0.490	-0.0782	Yes
147	Procr	11822	-0.529	-0.0770	Yes
148	Dnttip2	11907	-0.549	-0.0711	Yes
149	Rps27l	12014	-0.592	-0.0660	Yes
150	Ankra2	12187	-0.699	-0.0638	Yes
151	Coq8a	12243	-0.764	-0.0506	Yes
152	Xpc	12260	-0.800	-0.0333	Yes
153	Nupr1	12307	-0.879	-0.0166	Yes
154	Rpl36	12322	-0.907	0.0034	Yes