Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	HSC.HSC_Pheno.cls#Group2_versus_Group4.HSC_Pheno.cls#Group2_versus_Group4_repos
Phenotype	HSC_Pheno.cls#Group2_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.24985896
Normalized Enrichment Score (NES)	-1.098284
Nominal p-value	0.27087575
FDR q-value	0.8289202
FWER p-Value	0.953

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Nck1	96	0.872	0.0262	No
2	Cdk2	112	0.838	0.0576	No
3	Mapkap1	276	0.686	0.0711	No
4	Pin1	892	0.501	0.0405	No
5	Pten	1078	0.470	0.0438	No
6	Ppp1ca	1103	0.464	0.0599	No
7	Hsp90b1	1282	0.440	0.0626	No
8	Plcg1	1358	0.429	0.0732	No
9	Cxcr4	1379	0.425	0.0881	No
10	Cdk1	1457	0.415	0.0980	No
11	Vav3	1492	0.412	0.1113	No
12	Them4	2041	0.351	0.0803	No
13	Tiam1	2142	0.341	0.0855	No
14	Cdkn1b	2166	0.338	0.0968	No
15	Ralb	2574	0.301	0.0753	No
16	Rps6ka1	2617	0.296	0.0835	No
17	Rps6ka3	2699	0.292	0.0882	No
18	Mapk1	3141	0.251	0.0621	No
19	Ube2d3	3318	0.238	0.0570	No
20	Actr3	3329	0.237	0.0655	No
21	Arf1	3406	0.231	0.0683	No
22	Map2k3	3622	0.215	0.0591	No
23	Itpr2	3738	0.205	0.0578	No
24	Grb2	3740	0.205	0.0657	No
25	Cab39	4251	0.164	0.0305	No
26	Dusp3	4313	0.159	0.0317	No
27	Mknk2	4330	0.158	0.0366	No
28	Map3k7	4365	0.155	0.0399	No
29	Pdk1	4381	0.153	0.0446	No
30	Dapp1	4453	0.148	0.0446	No
31	Ywhab	4486	0.146	0.0477	No
32	Arpc3	4597	0.137	0.0440	No
33	Nfkbib	4877	0.116	0.0258	No
34	Calr	4926	0.113	0.0263	No
35	Mknk1	4950	0.112	0.0288	No
36	Stat2	5099	0.105	0.0209	No
37	Eif4e	5248	0.093	0.0124	No
38	Rac1	5284	0.090	0.0131	No
39	Mapk8	5491	0.075	-0.0007	No
40	Lck	5848	0.050	-0.0278	No
41	Ptpn11	6043	0.036	-0.0422	No
42	Gsk3b	6125	0.030	-0.0476	No
43	Tsc2	6226	0.022	-0.0549	No
44	Ripk1	6680	-0.008	-0.0915	No
45	Irak4	6801	-0.017	-0.1006	No
46	Acaca	7041	-0.032	-0.1189	No
47	Prkag1	7176	-0.043	-0.1281	No
48	Prkaa2	7178	-0.043	-0.1265	No
49	Smad2	7617	-0.079	-0.1591	No
50	Arhgdia	7674	-0.084	-0.1604	No
51	Atf1	7965	-0.104	-0.1800	No
52	Trib3	8264	-0.127	-0.1993	No
53	Sla	8380	-0.137	-0.2033	No
54	Il4	8572	-0.153	-0.2129	No
55	Ap2m1	8634	-0.157	-0.2118	No
56	Myd88	8797	-0.166	-0.2185	No
57	Tnfrsf1a	8881	-0.174	-0.2185	No
58	Ecsit	9061	-0.189	-0.2257	No
59	Map2k6	9251	-0.208	-0.2330	No
60	Tbk1	9459	-0.223	-0.2412	Yes
61	Slc2a1	9493	-0.225	-0.2351	Yes
62	Ube2n	9526	-0.229	-0.2287	Yes
63	Mapk9	9592	-0.236	-0.2248	Yes
64	Cfl1	9602	-0.237	-0.2163	Yes
65	Cltc	9622	-0.239	-0.2086	Yes
66	Ddit3	9791	-0.255	-0.2123	Yes
67	Gna14	10163	-0.288	-0.2313	Yes
68	Ppp2r1b	10173	-0.289	-0.2208	Yes
69	Prkcb	10201	-0.291	-0.2116	Yes
70	Akt1s1	10337	-0.307	-0.2106	Yes
71	E2f1	10643	-0.340	-0.2222	Yes
72	Rit1	10751	-0.354	-0.2172	Yes
73	Pak4	10814	-0.362	-0.2081	Yes
74	Sqstm1	10820	-0.362	-0.1944	Yes
75	Pla2g12a	10844	-0.366	-0.1820	Yes
76	Cab39l	10900	-0.374	-0.1719	Yes
77	Grk2	10949	-0.381	-0.1609	Yes
78	Actr2	10995	-0.386	-0.1496	Yes
79	Prkar2a	11030	-0.391	-0.1371	Yes
80	Il2rg	11273	-0.424	-0.1403	Yes
81	Traf2	11361	-0.434	-0.1305	Yes
82	Csnk2b	11599	-0.477	-0.1312	Yes
83	Nod1	11729	-0.507	-0.1219	Yes
84	Pikfyve	11733	-0.508	-0.1024	Yes
85	Akt1	12069	-0.617	-0.1056	Yes
86	Cdk4	12079	-0.621	-0.0822	Yes
87	Pfn1	12109	-0.642	-0.0595	Yes
88	Plcb1	12137	-0.650	-0.0364	Yes
89	Rptor	12146	-0.658	-0.0114	Yes
90	Raf1	12248	-0.743	0.0094	Yes