| Dataset | HSC.HSC_Pheno.cls#Group2_versus_Group4.HSC_Pheno.cls#Group2_versus_Group4_repos |
| Phenotype | HSC_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_MYC_TARGETS_V1 |
| Enrichment Score (ES) | -0.2083595 |
| Normalized Enrichment Score (NES) | -0.8473749 |
| Nominal p-value | 0.6320939 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Xrcc6 | 45 | 0.988 | 0.0157 | No |
| 2 | Psmd3 | 75 | 0.905 | 0.0311 | No |
| 3 | Cdk2 | 112 | 0.838 | 0.0446 | No |
| 4 | Snrpb2 | 365 | 0.645 | 0.0365 | No |
| 5 | Cad | 437 | 0.615 | 0.0427 | No |
| 6 | Srsf3 | 445 | 0.612 | 0.0542 | No |
| 7 | Eif4g2 | 486 | 0.598 | 0.0626 | No |
| 8 | Cct7 | 532 | 0.585 | 0.0704 | No |
| 9 | Hnrnpd | 576 | 0.570 | 0.0781 | No |
| 10 | Nop56 | 611 | 0.561 | 0.0863 | No |
| 11 | Pcna | 706 | 0.540 | 0.0892 | No |
| 12 | Cct4 | 857 | 0.509 | 0.0868 | No |
| 13 | Mrps18b | 899 | 0.499 | 0.0933 | No |
| 14 | Srsf1 | 902 | 0.499 | 0.1029 | No |
| 15 | Tra2b | 914 | 0.497 | 0.1117 | No |
| 16 | Mcm6 | 919 | 0.495 | 0.1211 | No |
| 17 | Tardbp | 1010 | 0.480 | 0.1232 | No |
| 18 | Rfc4 | 1118 | 0.462 | 0.1234 | No |
| 19 | Prdx3 | 1208 | 0.448 | 0.1249 | No |
| 20 | Rps5 | 1244 | 0.444 | 0.1307 | No |
| 21 | Snrpd3 | 1296 | 0.438 | 0.1351 | No |
| 22 | Pa2g4 | 1303 | 0.436 | 0.1432 | No |
| 23 | Ywhae | 1386 | 0.424 | 0.1448 | No |
| 24 | C1qbp | 1576 | 0.400 | 0.1371 | No |
| 25 | Got2 | 1601 | 0.397 | 0.1430 | No |
| 26 | Cdc20 | 1663 | 0.390 | 0.1456 | No |
| 27 | Psma4 | 1749 | 0.380 | 0.1461 | No |
| 28 | Psmd8 | 1812 | 0.374 | 0.1483 | No |
| 29 | Usp1 | 1832 | 0.372 | 0.1540 | No |
| 30 | Tyms | 1905 | 0.363 | 0.1553 | No |
| 31 | Cct3 | 1915 | 0.363 | 0.1616 | No |
| 32 | H2az1 | 2025 | 0.352 | 0.1596 | No |
| 33 | Vbp1 | 2061 | 0.349 | 0.1636 | No |
| 34 | Myc | 2100 | 0.344 | 0.1672 | No |
| 35 | Psma2 | 2180 | 0.337 | 0.1673 | No |
| 36 | Rrm1 | 2208 | 0.335 | 0.1717 | No |
| 37 | Rnps1 | 2295 | 0.328 | 0.1711 | No |
| 38 | Hnrnpa1 | 2352 | 0.322 | 0.1728 | No |
| 39 | Serbp1 | 2428 | 0.314 | 0.1728 | No |
| 40 | Syncrip | 2530 | 0.306 | 0.1705 | No |
| 41 | Psma7 | 2878 | 0.275 | 0.1474 | No |
| 42 | Hnrnpa2b1 | 3086 | 0.256 | 0.1354 | No |
| 43 | Snrpa | 3115 | 0.254 | 0.1381 | No |
| 44 | Rad23b | 3151 | 0.251 | 0.1401 | No |
| 45 | Abce1 | 3191 | 0.247 | 0.1418 | No |
| 46 | Cdc45 | 3290 | 0.240 | 0.1384 | No |
| 47 | Eef1b2 | 3312 | 0.238 | 0.1414 | No |
| 48 | Odc1 | 3360 | 0.234 | 0.1421 | No |
| 49 | Snrpg | 3384 | 0.231 | 0.1448 | No |
| 50 | Ssbp1 | 3488 | 0.223 | 0.1407 | No |
| 51 | Rplp0 | 3793 | 0.200 | 0.1197 | No |
| 52 | Erh | 3803 | 0.199 | 0.1228 | No |
| 53 | Cox5a | 3924 | 0.187 | 0.1166 | No |
| 54 | Eif3d | 3956 | 0.184 | 0.1177 | No |
| 55 | Hnrnpc | 4259 | 0.163 | 0.0961 | No |
| 56 | Hnrnpu | 4331 | 0.158 | 0.0934 | No |
| 57 | Nme1 | 4354 | 0.156 | 0.0946 | No |
| 58 | Srsf2 | 4515 | 0.144 | 0.0843 | No |
| 59 | Ruvbl2 | 4559 | 0.139 | 0.0835 | No |
| 60 | Sf3a1 | 4651 | 0.132 | 0.0786 | No |
| 61 | Slc25a3 | 4817 | 0.120 | 0.0674 | No |
| 62 | Fam120a | 4844 | 0.118 | 0.0676 | No |
| 63 | Canx | 5116 | 0.104 | 0.0474 | No |
| 64 | Psma6 | 5172 | 0.099 | 0.0448 | No |
| 65 | Eif4e | 5248 | 0.093 | 0.0405 | No |
| 66 | Uba2 | 5264 | 0.092 | 0.0411 | No |
| 67 | Mrpl9 | 5293 | 0.089 | 0.0405 | No |
| 68 | Tufm | 5298 | 0.089 | 0.0419 | No |
| 69 | Eif3j1 | 5300 | 0.088 | 0.0436 | No |
| 70 | Vdac3 | 5359 | 0.084 | 0.0405 | No |
| 71 | Nap1l1 | 5416 | 0.080 | 0.0374 | No |
| 72 | G3bp1 | 5515 | 0.073 | 0.0308 | No |
| 73 | Tcp1 | 5521 | 0.073 | 0.0318 | No |
| 74 | Ran | 5653 | 0.064 | 0.0223 | No |
| 75 | Glo1 | 5703 | 0.060 | 0.0195 | No |
| 76 | Cct2 | 5806 | 0.053 | 0.0122 | No |
| 77 | Hdac2 | 5896 | 0.047 | 0.0058 | No |
| 78 | Ilf2 | 6229 | 0.022 | -0.0211 | No |
| 79 | Cyc1 | 6275 | 0.018 | -0.0244 | No |
| 80 | Srpk1 | 6296 | 0.017 | -0.0257 | No |
| 81 | Hnrnpr | 6324 | 0.015 | -0.0276 | No |
| 82 | Ndufab1 | 6402 | 0.009 | -0.0338 | No |
| 83 | Txnl4a | 6414 | 0.008 | -0.0345 | No |
| 84 | Mrpl23 | 6416 | 0.008 | -0.0344 | No |
| 85 | Psmd14 | 6449 | 0.006 | -0.0370 | No |
| 86 | Pabpc4 | 6469 | 0.004 | -0.0384 | No |
| 87 | Psmb3 | 6485 | 0.003 | -0.0396 | No |
| 88 | Cops5 | 6514 | 0.001 | -0.0419 | No |
| 89 | Ifrd1 | 6657 | -0.006 | -0.0534 | No |
| 90 | Mcm7 | 6718 | -0.010 | -0.0582 | No |
| 91 | Dut | 6728 | -0.011 | -0.0587 | No |
| 92 | Pcbp1 | 6768 | -0.014 | -0.0616 | No |
| 93 | Prps2 | 6806 | -0.017 | -0.0643 | No |
| 94 | Ncbp2 | 6929 | -0.026 | -0.0738 | No |
| 95 | Xpot | 6940 | -0.027 | -0.0741 | No |
| 96 | Mcm4 | 6969 | -0.029 | -0.0759 | No |
| 97 | Hspe1 | 7003 | -0.030 | -0.0780 | No |
| 98 | Psmd7 | 7034 | -0.032 | -0.0798 | No |
| 99 | Stard7 | 7126 | -0.039 | -0.0865 | No |
| 100 | Ddx21 | 7169 | -0.042 | -0.0891 | No |
| 101 | Mcm2 | 7173 | -0.043 | -0.0886 | No |
| 102 | Vdac1 | 7196 | -0.045 | -0.0895 | No |
| 103 | Ncbp1 | 7213 | -0.046 | -0.0899 | No |
| 104 | Psma1 | 7222 | -0.047 | -0.0896 | No |
| 105 | Pwp1 | 7289 | -0.053 | -0.0940 | No |
| 106 | Ddx18 | 7372 | -0.060 | -0.0996 | No |
| 107 | Lsm2 | 7530 | -0.072 | -0.1111 | No |
| 108 | Eif4a1 | 7559 | -0.074 | -0.1119 | No |
| 109 | Smarcc1 | 7578 | -0.076 | -0.1119 | No |
| 110 | Nolc1 | 7593 | -0.077 | -0.1115 | No |
| 111 | Bub3 | 7606 | -0.078 | -0.1110 | No |
| 112 | Rpl6 | 7625 | -0.080 | -0.1109 | No |
| 113 | Clns1a | 7834 | -0.095 | -0.1261 | No |
| 114 | Prdx4 | 8240 | -0.125 | -0.1569 | No |
| 115 | Cul1 | 8396 | -0.138 | -0.1669 | No |
| 116 | Rrp9 | 8423 | -0.140 | -0.1663 | No |
| 117 | Rps2 | 8428 | -0.140 | -0.1639 | No |
| 118 | Hsp90ab1 | 8448 | -0.142 | -0.1627 | No |
| 119 | Ssb | 8527 | -0.149 | -0.1662 | No |
| 120 | Rps6 | 8579 | -0.153 | -0.1673 | No |
| 121 | Snrpa1 | 8584 | -0.154 | -0.1647 | No |
| 122 | Exosc7 | 8635 | -0.157 | -0.1657 | No |
| 123 | Tomm70a | 8784 | -0.166 | -0.1746 | No |
| 124 | Psmc6 | 8788 | -0.166 | -0.1716 | No |
| 125 | Rpl14 | 8849 | -0.172 | -0.1731 | No |
| 126 | Rack1 | 8891 | -0.176 | -0.1731 | No |
| 127 | Eif3b | 9103 | -0.193 | -0.1866 | No |
| 128 | Aimp2 | 9121 | -0.195 | -0.1842 | No |
| 129 | Eif2s2 | 9269 | -0.210 | -0.1921 | No |
| 130 | Nop16 | 9336 | -0.215 | -0.1933 | No |
| 131 | Psmb2 | 9520 | -0.229 | -0.2039 | Yes |
| 132 | Npm1 | 9564 | -0.233 | -0.2028 | Yes |
| 133 | Ranbp1 | 9604 | -0.237 | -0.2014 | Yes |
| 134 | Fbl | 9627 | -0.239 | -0.1985 | Yes |
| 135 | Snrpd1 | 9666 | -0.244 | -0.1968 | Yes |
| 136 | Hdgf | 9693 | -0.247 | -0.1941 | Yes |
| 137 | Xpo1 | 9851 | -0.260 | -0.2019 | Yes |
| 138 | Rpl22 | 9869 | -0.262 | -0.1982 | Yes |
| 139 | Ppia | 9909 | -0.264 | -0.1962 | Yes |
| 140 | Sf3b3 | 9945 | -0.268 | -0.1938 | Yes |
| 141 | Apex1 | 10013 | -0.274 | -0.1939 | Yes |
| 142 | Kpnb1 | 10053 | -0.279 | -0.1917 | Yes |
| 143 | Prpf31 | 10186 | -0.290 | -0.1968 | Yes |
| 144 | Mad2l1 | 10198 | -0.291 | -0.1920 | Yes |
| 145 | Dhx15 | 10289 | -0.301 | -0.1935 | Yes |
| 146 | Cnbp | 10353 | -0.309 | -0.1926 | Yes |
| 147 | Rps10 | 10385 | -0.312 | -0.1890 | Yes |
| 148 | Mcm5 | 10466 | -0.321 | -0.1893 | Yes |
| 149 | Ldha | 10470 | -0.321 | -0.1833 | Yes |
| 150 | Ap3s1 | 10509 | -0.326 | -0.1800 | Yes |
| 151 | Psmc4 | 10513 | -0.327 | -0.1738 | Yes |
| 152 | Snrpd2 | 10522 | -0.328 | -0.1681 | Yes |
| 153 | Etf1 | 10608 | -0.335 | -0.1685 | Yes |
| 154 | Hnrnpa3 | 10627 | -0.338 | -0.1633 | Yes |
| 155 | Pabpc1 | 10766 | -0.356 | -0.1677 | Yes |
| 156 | Impdh2 | 10810 | -0.361 | -0.1641 | Yes |
| 157 | Trim28 | 10876 | -0.371 | -0.1622 | Yes |
| 158 | Pole3 | 10924 | -0.379 | -0.1586 | Yes |
| 159 | Hddc2 | 11061 | -0.394 | -0.1620 | Yes |
| 160 | Ube2e1 | 11063 | -0.395 | -0.1544 | Yes |
| 161 | Cct5 | 11174 | -0.409 | -0.1554 | Yes |
| 162 | Gnl3 | 11185 | -0.411 | -0.1481 | Yes |
| 163 | Acp1 | 11194 | -0.412 | -0.1407 | Yes |
| 164 | Ccna2 | 11324 | -0.428 | -0.1429 | Yes |
| 165 | Eif4h | 11374 | -0.436 | -0.1384 | Yes |
| 166 | Hspd1 | 11377 | -0.436 | -0.1300 | Yes |
| 167 | Nhp2 | 11466 | -0.453 | -0.1283 | Yes |
| 168 | Psmd1 | 11522 | -0.463 | -0.1238 | Yes |
| 169 | Tfdp1 | 11553 | -0.467 | -0.1171 | Yes |
| 170 | Rsl1d1 | 11562 | -0.468 | -0.1085 | Yes |
| 171 | Srsf7 | 11623 | -0.482 | -0.1040 | Yes |
| 172 | Pgk1 | 11670 | -0.490 | -0.0982 | Yes |
| 173 | Gspt1 | 11710 | -0.503 | -0.0915 | Yes |
| 174 | Eif2s1 | 11713 | -0.504 | -0.0818 | Yes |
| 175 | Rps3 | 11747 | -0.510 | -0.0745 | Yes |
| 176 | Phb2 | 11783 | -0.519 | -0.0672 | Yes |
| 177 | Cstf2 | 11785 | -0.520 | -0.0571 | Yes |
| 178 | Pold2 | 11807 | -0.524 | -0.0485 | Yes |
| 179 | Dek | 11821 | -0.528 | -0.0392 | Yes |
| 180 | Rpl18 | 11901 | -0.551 | -0.0349 | Yes |
| 181 | Cbx3 | 11927 | -0.559 | -0.0260 | Yes |
| 182 | Ppm1g | 12002 | -0.584 | -0.0206 | Yes |
| 183 | Cdk4 | 12079 | -0.621 | -0.0147 | Yes |
| 184 | Srm | 12099 | -0.632 | -0.0038 | Yes |
| 185 | Ywhaq | 12110 | -0.642 | 0.0080 | Yes |
| 186 | Orc2 | 12128 | -0.648 | 0.0193 | Yes |

