Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	HSC.HSC_Pheno.cls#Group2_versus_Group3.HSC_Pheno.cls#Group2_versus_Group3_repos
Phenotype	HSC_Pheno.cls#Group2_versus_Group3_repos
Upregulated in class	2
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.31003764
Normalized Enrichment Score (NES)	-1.4030885
Nominal p-value	0.020576132
FDR q-value	0.86957216
FWER p-Value	0.537

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Mapk9	118	0.815	0.0225	No
2	Hsp90b1	145	0.786	0.0513	No
3	Rps6ka3	537	0.568	0.0418	No
4	Il2rg	853	0.487	0.0353	No
5	Cdk2	1427	0.392	0.0040	No
6	Stat2	1741	0.359	-0.0073	No
7	Map2k3	1809	0.350	0.0010	No
8	Pak4	1907	0.339	0.0064	No
9	Them4	1911	0.338	0.0195	No
10	Arf1	2044	0.325	0.0215	No
11	Mapkap1	2147	0.312	0.0255	No
12	Il4	2148	0.312	0.0377	No
13	Mapk1	2359	0.290	0.0320	No
14	Rps6ka1	2377	0.287	0.0420	No
15	Traf2	2550	0.267	0.0385	No
16	Arpc3	2590	0.263	0.0456	No
17	Ywhab	2787	0.247	0.0394	No
18	Ddit3	2806	0.244	0.0475	No
19	Ube2d3	3122	0.214	0.0303	No
20	Grb2	3133	0.213	0.0378	No
21	Ppp1ca	3277	0.198	0.0340	No
22	E2f1	3439	0.185	0.0281	No
23	Mapk8	3472	0.183	0.0327	No
24	Mknk2	3514	0.179	0.0364	No
25	Prkaa2	3530	0.178	0.0422	No
26	Tiam1	3582	0.174	0.0449	No
27	Acaca	3586	0.174	0.0515	No
28	Grk2	3853	0.155	0.0359	No
29	Nck1	4172	0.131	0.0151	No
30	Pdk1	4294	0.121	0.0101	No
31	Arhgdia	4341	0.118	0.0109	No
32	Nod1	4435	0.111	0.0077	No
33	Cdkn1b	4739	0.092	-0.0133	No
34	Atf1	4791	0.088	-0.0140	No
35	Plcg1	5052	0.068	-0.0325	No
36	Actr2	5295	0.051	-0.0503	No
37	Vav3	5306	0.050	-0.0491	No
38	Map2k6	5313	0.050	-0.0476	No
39	Ppp2r1b	5486	0.036	-0.0602	No
40	Ptpn11	5498	0.035	-0.0598	No
41	Myd88	5609	0.028	-0.0676	No
42	Smad2	5682	0.023	-0.0726	No
43	Eif4e	6008	0.001	-0.0990	No
44	Map3k7	6195	-0.007	-0.1139	No
45	Pten	6368	-0.019	-0.1272	No
46	Cxcr4	6464	-0.026	-0.1339	No
47	Mknk1	6609	-0.037	-0.1441	No
48	Calr	6812	-0.051	-0.1586	No
49	Dapp1	6851	-0.054	-0.1596	No
50	Actr3	7151	-0.076	-0.1809	No
51	Nfkbib	7272	-0.086	-0.1873	No
52	Cfl1	7342	-0.092	-0.1893	No
53	Itpr2	7647	-0.116	-0.2095	No
54	Ralb	7685	-0.119	-0.2079	No
55	Akt1	7695	-0.120	-0.2039	No
56	Sqstm1	8733	-0.198	-0.2806	No
57	Sla	9065	-0.223	-0.2988	No
58	Cab39	9068	-0.224	-0.2901	No
59	Dusp3	9215	-0.236	-0.2927	No
60	Trib3	9365	-0.247	-0.2951	No
61	Tsc2	9549	-0.264	-0.2997	Yes
62	Ecsit	9660	-0.274	-0.2979	Yes
63	Cltc	9714	-0.279	-0.2912	Yes
64	Lck	9745	-0.281	-0.2826	Yes
65	Gna14	9800	-0.286	-0.2758	Yes
66	Tnfrsf1a	9857	-0.291	-0.2689	Yes
67	Pin1	10002	-0.300	-0.2688	Yes
68	Cdk1	10105	-0.310	-0.2649	Yes
69	Ube2n	10137	-0.313	-0.2551	Yes
70	Ripk1	10269	-0.324	-0.2531	Yes
71	Rac1	10386	-0.333	-0.2494	Yes
72	Pla2g12a	10508	-0.348	-0.2455	Yes
73	Irak4	10597	-0.359	-0.2386	Yes
74	Tbk1	10827	-0.389	-0.2419	Yes
75	Akt1s1	10933	-0.404	-0.2346	Yes
76	Cab39l	10965	-0.410	-0.2210	Yes
77	Rit1	10974	-0.411	-0.2054	Yes
78	Prkcb	10975	-0.411	-0.1892	Yes
79	Ap2m1	11181	-0.441	-0.1886	Yes
80	Rptor	11186	-0.442	-0.1715	Yes
81	Prkar2a	11282	-0.455	-0.1613	Yes
82	Slc2a1	11452	-0.485	-0.1560	Yes
83	Pikfyve	11545	-0.502	-0.1438	Yes
84	Plcb1	11619	-0.519	-0.1293	Yes
85	Pfn1	11660	-0.529	-0.1117	Yes
86	Gsk3b	11735	-0.548	-0.0962	Yes
87	Raf1	12131	-0.707	-0.1006	Yes
88	Cdk4	12266	-0.814	-0.0795	Yes
89	Csnk2b	12274	-0.825	-0.0476	Yes
90	Prkag1	12359	-1.392	0.0003	Yes