| Dataset | HSC.HSC_Pheno.cls#Group2_versus_Group3.HSC_Pheno.cls#Group2_versus_Group3_repos |
| Phenotype | HSC_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | -0.39601117 |
| Normalized Enrichment Score (NES) | -1.3042666 |
| Nominal p-value | 0.11983471 |
| FDR q-value | 0.61252344 |
| FWER p-Value | 0.767 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Nudt21 | 190 | 0.746 | -0.0010 | No |
| 2 | Ubr7 | 296 | 0.669 | 0.0035 | No |
| 3 | Zw10 | 467 | 0.594 | 0.0012 | No |
| 4 | Gins3 | 485 | 0.586 | 0.0113 | No |
| 5 | Hnrnpd | 520 | 0.574 | 0.0197 | No |
| 6 | Xrcc6 | 549 | 0.565 | 0.0285 | No |
| 7 | Smc1a | 623 | 0.540 | 0.0331 | No |
| 8 | Rad1 | 742 | 0.510 | 0.0334 | No |
| 9 | Psmc3ip | 782 | 0.503 | 0.0400 | No |
| 10 | Ing3 | 920 | 0.473 | 0.0380 | No |
| 11 | Tra2b | 948 | 0.469 | 0.0450 | No |
| 12 | Eed | 957 | 0.468 | 0.0535 | No |
| 13 | Smc6 | 1309 | 0.407 | 0.0327 | No |
| 14 | Dlgap5 | 1848 | 0.346 | -0.0047 | No |
| 15 | Rfc3 | 2078 | 0.321 | -0.0172 | No |
| 16 | Mlh1 | 2157 | 0.311 | -0.0175 | No |
| 17 | Wdr90 | 2178 | 0.310 | -0.0131 | No |
| 18 | Cdc25b | 2279 | 0.300 | -0.0154 | No |
| 19 | Pa2g4 | 2382 | 0.287 | -0.0182 | No |
| 20 | E2f8 | 2773 | 0.247 | -0.0453 | No |
| 21 | Tacc3 | 3132 | 0.213 | -0.0705 | No |
| 22 | Rpa3 | 3199 | 0.206 | -0.0719 | No |
| 23 | Pcna | 3408 | 0.188 | -0.0853 | No |
| 24 | Pms2 | 3667 | 0.171 | -0.1031 | No |
| 25 | Hmgb2 | 3755 | 0.163 | -0.1071 | No |
| 26 | Msh2 | 3877 | 0.153 | -0.1140 | No |
| 27 | Cse1l | 3882 | 0.153 | -0.1114 | No |
| 28 | Spag5 | 3994 | 0.145 | -0.1176 | No |
| 29 | Stmn1 | 4012 | 0.143 | -0.1162 | No |
| 30 | Ipo7 | 4072 | 0.140 | -0.1183 | No |
| 31 | Luc7l3 | 4278 | 0.123 | -0.1327 | No |
| 32 | Ncapd2 | 4317 | 0.119 | -0.1335 | No |
| 33 | Mcm7 | 4404 | 0.113 | -0.1384 | No |
| 34 | Tipin | 4614 | 0.102 | -0.1535 | No |
| 35 | Cdkn1b | 4739 | 0.092 | -0.1619 | No |
| 36 | Ddx39a | 4748 | 0.091 | -0.1608 | No |
| 37 | Stag1 | 4818 | 0.086 | -0.1648 | No |
| 38 | Orc2 | 4862 | 0.082 | -0.1667 | No |
| 39 | Prps1 | 4901 | 0.080 | -0.1682 | No |
| 40 | Mybl2 | 4905 | 0.079 | -0.1669 | No |
| 41 | Rfc1 | 4956 | 0.076 | -0.1695 | No |
| 42 | H2az1 | 5037 | 0.069 | -0.1747 | No |
| 43 | Asf1a | 5239 | 0.055 | -0.1902 | No |
| 44 | Usp1 | 5272 | 0.053 | -0.1918 | No |
| 45 | Ak2 | 5368 | 0.045 | -0.1987 | No |
| 46 | Rad21 | 5456 | 0.038 | -0.2051 | No |
| 47 | Kif4 | 5610 | 0.028 | -0.2171 | No |
| 48 | Nup107 | 5635 | 0.026 | -0.2185 | No |
| 49 | Dctpp1 | 5840 | 0.013 | -0.2350 | No |
| 50 | Dclre1b | 5890 | 0.010 | -0.2389 | No |
| 51 | Ranbp1 | 5935 | 0.006 | -0.2424 | No |
| 52 | Spc25 | 6020 | 0.000 | -0.2493 | No |
| 53 | Nop56 | 6116 | -0.002 | -0.2570 | No |
| 54 | Lig1 | 6134 | -0.003 | -0.2583 | No |
| 55 | Srsf1 | 6153 | -0.005 | -0.2597 | No |
| 56 | Xpo1 | 6277 | -0.013 | -0.2695 | No |
| 57 | Mcm6 | 6294 | -0.015 | -0.2706 | No |
| 58 | Ran | 6491 | -0.028 | -0.2861 | No |
| 59 | Lbr | 6639 | -0.039 | -0.2974 | No |
| 60 | Orc6 | 6656 | -0.041 | -0.2979 | No |
| 61 | Nup153 | 6782 | -0.049 | -0.3072 | No |
| 62 | Snrpb | 6811 | -0.051 | -0.3085 | No |
| 63 | Tubb5 | 6843 | -0.053 | -0.3100 | No |
| 64 | Rad50 | 6854 | -0.054 | -0.3098 | No |
| 65 | Nbn | 6899 | -0.057 | -0.3123 | No |
| 66 | Ppm1d | 6916 | -0.059 | -0.3124 | No |
| 67 | Rbbp7 | 7037 | -0.068 | -0.3209 | No |
| 68 | Racgap1 | 7117 | -0.073 | -0.3260 | No |
| 69 | Ezh2 | 7121 | -0.074 | -0.3248 | No |
| 70 | Suv39h1 | 7213 | -0.080 | -0.3307 | No |
| 71 | Pole | 7217 | -0.081 | -0.3294 | No |
| 72 | Cdc20 | 7230 | -0.082 | -0.3287 | No |
| 73 | Mcm2 | 7245 | -0.084 | -0.3282 | No |
| 74 | Dnmt1 | 7277 | -0.086 | -0.3291 | No |
| 75 | Syncrip | 7278 | -0.086 | -0.3274 | No |
| 76 | Anp32e | 7320 | -0.090 | -0.3290 | No |
| 77 | Nme1 | 7335 | -0.092 | -0.3284 | No |
| 78 | Cdc25a | 7343 | -0.092 | -0.3271 | No |
| 79 | Srsf2 | 7351 | -0.093 | -0.3259 | No |
| 80 | Ube2s | 7353 | -0.094 | -0.3241 | No |
| 81 | Slbp | 7470 | -0.102 | -0.3317 | No |
| 82 | Pttg1 | 7521 | -0.106 | -0.3337 | No |
| 83 | Brms1l | 7771 | -0.126 | -0.3517 | No |
| 84 | Nap1l1 | 7784 | -0.126 | -0.3502 | No |
| 85 | Ssrp1 | 7906 | -0.135 | -0.3575 | No |
| 86 | Cenpe | 7960 | -0.140 | -0.3591 | No |
| 87 | Ccne1 | 8038 | -0.147 | -0.3625 | No |
| 88 | Bub1b | 8074 | -0.150 | -0.3624 | No |
| 89 | Mcm4 | 8138 | -0.154 | -0.3646 | No |
| 90 | Mthfd2 | 8260 | -0.165 | -0.3713 | No |
| 91 | Pold3 | 8266 | -0.165 | -0.3685 | No |
| 92 | Rnaseh2a | 8359 | -0.172 | -0.3727 | No |
| 93 | Rpa1 | 8435 | -0.178 | -0.3753 | No |
| 94 | Smc3 | 8509 | -0.183 | -0.3777 | No |
| 95 | Ube2t | 8542 | -0.186 | -0.3767 | No |
| 96 | Myc | 8610 | -0.191 | -0.3785 | No |
| 97 | Donson | 8644 | -0.194 | -0.3774 | No |
| 98 | Jpt1 | 8719 | -0.197 | -0.3796 | No |
| 99 | Chek2 | 8759 | -0.200 | -0.3789 | No |
| 100 | Cit | 8808 | -0.205 | -0.3788 | No |
| 101 | Nolc1 | 8962 | -0.215 | -0.3872 | No |
| 102 | Pds5b | 9006 | -0.218 | -0.3865 | No |
| 103 | Lmnb1 | 9055 | -0.223 | -0.3860 | No |
| 104 | Birc5 | 9104 | -0.228 | -0.3855 | No |
| 105 | Nasp | 9166 | -0.233 | -0.3859 | No |
| 106 | Prkdc | 9216 | -0.236 | -0.3853 | No |
| 107 | Hells | 9268 | -0.241 | -0.3848 | No |
| 108 | Hmmr | 9376 | -0.248 | -0.3887 | No |
| 109 | Top2a | 9393 | -0.250 | -0.3852 | No |
| 110 | Ccp110 | 9397 | -0.250 | -0.3805 | No |
| 111 | Cbx5 | 9536 | -0.262 | -0.3867 | No |
| 112 | Tfrc | 9637 | -0.270 | -0.3896 | No |
| 113 | Ctcf | 9716 | -0.279 | -0.3906 | Yes |
| 114 | Lsm8 | 9761 | -0.283 | -0.3886 | Yes |
| 115 | Exosc8 | 9793 | -0.286 | -0.3856 | Yes |
| 116 | Rrm2 | 9798 | -0.286 | -0.3803 | Yes |
| 117 | Hus1 | 9855 | -0.291 | -0.3792 | Yes |
| 118 | Mms22l | 9877 | -0.292 | -0.3752 | Yes |
| 119 | Rfc2 | 9893 | -0.294 | -0.3707 | Yes |
| 120 | Lyar | 9922 | -0.295 | -0.3672 | Yes |
| 121 | Dck | 10001 | -0.300 | -0.3677 | Yes |
| 122 | Gins1 | 10021 | -0.303 | -0.3633 | Yes |
| 123 | Cdk1 | 10105 | -0.310 | -0.3641 | Yes |
| 124 | Rpa2 | 10212 | -0.319 | -0.3665 | Yes |
| 125 | Pole4 | 10246 | -0.322 | -0.3630 | Yes |
| 126 | Cdkn2c | 10279 | -0.325 | -0.3592 | Yes |
| 127 | Diaph3 | 10297 | -0.326 | -0.3542 | Yes |
| 128 | Mki67 | 10341 | -0.330 | -0.3513 | Yes |
| 129 | Cks2 | 10362 | -0.332 | -0.3464 | Yes |
| 130 | Bard1 | 10374 | -0.332 | -0.3408 | Yes |
| 131 | Pan2 | 10377 | -0.332 | -0.3345 | Yes |
| 132 | Hmgb3 | 10403 | -0.337 | -0.3299 | Yes |
| 133 | Dut | 10429 | -0.340 | -0.3253 | Yes |
| 134 | Tbrg4 | 10497 | -0.348 | -0.3240 | Yes |
| 135 | Rad51ap1 | 10504 | -0.348 | -0.3177 | Yes |
| 136 | H2ax | 10505 | -0.348 | -0.3109 | Yes |
| 137 | Cnot9 | 10550 | -0.353 | -0.3076 | Yes |
| 138 | Cdca8 | 10579 | -0.357 | -0.3029 | Yes |
| 139 | Prdx4 | 10610 | -0.361 | -0.2983 | Yes |
| 140 | Brca2 | 10654 | -0.365 | -0.2947 | Yes |
| 141 | Pola2 | 10705 | -0.371 | -0.2915 | Yes |
| 142 | Ilf3 | 10777 | -0.382 | -0.2898 | Yes |
| 143 | Brca1 | 10793 | -0.384 | -0.2835 | Yes |
| 144 | Plk4 | 10846 | -0.392 | -0.2801 | Yes |
| 145 | Gins4 | 11040 | -0.420 | -0.2878 | Yes |
| 146 | Phf5a | 11086 | -0.426 | -0.2831 | Yes |
| 147 | Tk1 | 11124 | -0.432 | -0.2777 | Yes |
| 148 | Aurka | 11182 | -0.441 | -0.2737 | Yes |
| 149 | Nup205 | 11193 | -0.443 | -0.2659 | Yes |
| 150 | Chek1 | 11245 | -0.450 | -0.2613 | Yes |
| 151 | Tubg1 | 11247 | -0.450 | -0.2525 | Yes |
| 152 | Mre11a | 11275 | -0.455 | -0.2458 | Yes |
| 153 | Tmpo | 11321 | -0.461 | -0.2405 | Yes |
| 154 | Gspt1 | 11356 | -0.467 | -0.2342 | Yes |
| 155 | Shmt1 | 11363 | -0.468 | -0.2255 | Yes |
| 156 | Ccnb2 | 11402 | -0.475 | -0.2193 | Yes |
| 157 | Mcm3 | 11516 | -0.495 | -0.2189 | Yes |
| 158 | Pold2 | 11613 | -0.517 | -0.2166 | Yes |
| 159 | Smc4 | 11628 | -0.521 | -0.2076 | Yes |
| 160 | Prim2 | 11672 | -0.531 | -0.2007 | Yes |
| 161 | Psip1 | 11679 | -0.532 | -0.1908 | Yes |
| 162 | Paics | 11682 | -0.533 | -0.1805 | Yes |
| 163 | Ppp1r8 | 11700 | -0.536 | -0.1714 | Yes |
| 164 | Dek | 11707 | -0.538 | -0.1614 | Yes |
| 165 | Depdc1a | 11750 | -0.551 | -0.1540 | Yes |
| 166 | Dscc1 | 11877 | -0.593 | -0.1527 | Yes |
| 167 | Mad2l1 | 11903 | -0.602 | -0.1430 | Yes |
| 168 | Trip13 | 11904 | -0.602 | -0.1312 | Yes |
| 169 | Cenpm | 11923 | -0.610 | -0.1207 | Yes |
| 170 | Atad2 | 11955 | -0.621 | -0.1111 | Yes |
| 171 | Kif18b | 11971 | -0.628 | -0.1000 | Yes |
| 172 | Pnn | 11992 | -0.639 | -0.0892 | Yes |
| 173 | Pold1 | 12059 | -0.671 | -0.0814 | Yes |
| 174 | Trp53 | 12064 | -0.673 | -0.0686 | Yes |
| 175 | Timeless | 12083 | -0.679 | -0.0568 | Yes |
| 176 | Eif2s1 | 12249 | -0.794 | -0.0548 | Yes |
| 177 | Cdk4 | 12266 | -0.814 | -0.0401 | Yes |
| 178 | Mcm5 | 12327 | -0.962 | -0.0262 | Yes |
| 179 | Wee1 | 12362 | -1.485 | 0.0001 | Yes |

