Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | HSC.HSC_Pheno.cls#Group1_versus_Group3.HSC_Pheno.cls#Group1_versus_Group3_repos |
| Phenotype | HSC_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_IL6_JAK_STAT3_SIGNALING |
| Enrichment Score (ES) | 0.387177 |
| Normalized Enrichment Score (NES) | 1.5342599 |
| Nominal p-value | 0.013861386 |
| FDR q-value | 0.35768393 |
| FWER p-Value | 0.296 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Irf1 | 161 | 0.874 | 0.0407 | Yes |
| 2 | Osmr | 185 | 0.844 | 0.0908 | Yes |
| 3 | Csf1 | 220 | 0.799 | 0.1373 | Yes |
| 4 | Stam2 | 263 | 0.771 | 0.1813 | Yes |
| 5 | Stat2 | 349 | 0.718 | 0.2186 | Yes |
| 6 | Il12rb1 | 424 | 0.675 | 0.2541 | Yes |
| 7 | Grb2 | 475 | 0.641 | 0.2895 | Yes |
| 8 | Jun | 952 | 0.502 | 0.2818 | Yes |
| 9 | Il2rg | 1141 | 0.461 | 0.2949 | Yes |
| 10 | Hax1 | 1203 | 0.448 | 0.3175 | Yes |
| 11 | Socs3 | 1532 | 0.401 | 0.3155 | Yes |
| 12 | Pim1 | 1834 | 0.365 | 0.3136 | Yes |
| 13 | Crlf2 | 2004 | 0.341 | 0.3208 | Yes |
| 14 | Cd38 | 2133 | 0.324 | 0.3303 | Yes |
| 15 | Il4ra | 2225 | 0.315 | 0.3424 | Yes |
| 16 | Bak1 | 2397 | 0.294 | 0.3466 | Yes |
| 17 | Ifnar1 | 2477 | 0.283 | 0.3576 | Yes |
| 18 | Fas | 2630 | 0.269 | 0.3617 | Yes |
| 19 | Csf3r | 2739 | 0.260 | 0.3690 | Yes |
| 20 | Tnfrsf1b | 3017 | 0.232 | 0.3608 | Yes |
| 21 | Il18r1 | 3132 | 0.224 | 0.3653 | Yes |
| 22 | Ebi3 | 3302 | 0.209 | 0.3644 | Yes |
| 23 | Pik3r5 | 3306 | 0.209 | 0.3771 | Yes |
| 24 | Ltb | 3432 | 0.202 | 0.3794 | Yes |
| 25 | Il6st | 3487 | 0.198 | 0.3872 | Yes |
| 26 | Map3k8 | 3775 | 0.174 | 0.3746 | No |
| 27 | Itgb3 | 3981 | 0.157 | 0.3676 | No |
| 28 | Il3ra | 4191 | 0.139 | 0.3592 | No |
| 29 | Myd88 | 4769 | 0.094 | 0.3181 | No |
| 30 | Tyk2 | 5212 | 0.061 | 0.2859 | No |
| 31 | Pdgfc | 5566 | 0.036 | 0.2595 | No |
| 32 | Ifngr1 | 5822 | 0.018 | 0.2399 | No |
| 33 | Il7 | 5856 | 0.016 | 0.2382 | No |
| 34 | Il15ra | 6404 | -0.018 | 0.1949 | No |
| 35 | Csf2ra | 6642 | -0.035 | 0.1777 | No |
| 36 | Stat1 | 6710 | -0.040 | 0.1747 | No |
| 37 | Cd44 | 6722 | -0.040 | 0.1763 | No |
| 38 | Irf9 | 6902 | -0.053 | 0.1650 | No |
| 39 | Il17ra | 7018 | -0.060 | 0.1594 | No |
| 40 | Il10rb | 7051 | -0.062 | 0.1606 | No |
| 41 | Ltbr | 7065 | -0.063 | 0.1634 | No |
| 42 | Tlr2 | 7380 | -0.082 | 0.1430 | No |
| 43 | Tgfb1 | 7830 | -0.113 | 0.1135 | No |
| 44 | Stat3 | 8155 | -0.135 | 0.0954 | No |
| 45 | Ptpn2 | 8829 | -0.182 | 0.0520 | No |
| 46 | Ptpn1 | 9131 | -0.206 | 0.0402 | No |
| 47 | Cd9 | 9161 | -0.208 | 0.0506 | No |
| 48 | Socs1 | 9212 | -0.210 | 0.0595 | No |
| 49 | Il1r1 | 9288 | -0.216 | 0.0667 | No |
| 50 | Acvr1b | 9860 | -0.265 | 0.0366 | No |
| 51 | Ptpn11 | 9914 | -0.270 | 0.0489 | No |
| 52 | Cbl | 11090 | -0.399 | -0.0220 | No |
| 53 | Ifngr2 | 11246 | -0.425 | -0.0084 | No |
| 54 | Itga4 | 11567 | -0.482 | -0.0047 | No |
| 55 | Tnfrsf1a | 11609 | -0.489 | 0.0220 | No |
| 56 | Tnfrsf21 | 12092 | -0.636 | 0.0220 | No |
