| Dataset | HSC.HSC_Pheno.cls#Group1_versus_Group2.HSC_Pheno.cls#Group1_versus_Group2_repos |
| Phenotype | HSC_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | 0.17661077 |
| Normalized Enrichment Score (NES) | 0.8157725 |
| Nominal p-value | 0.8358209 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Insig1 | 74 | 0.992 | 0.0171 | Yes |
| 2 | Stard4 | 143 | 0.852 | 0.0314 | Yes |
| 3 | Dhcr7 | 255 | 0.748 | 0.0397 | Yes |
| 4 | Tm7sf2 | 468 | 0.647 | 0.0375 | Yes |
| 5 | Rit1 | 526 | 0.629 | 0.0475 | Yes |
| 6 | Nfyc | 712 | 0.574 | 0.0457 | Yes |
| 7 | Tomm40 | 755 | 0.565 | 0.0554 | Yes |
| 8 | Gtf2h1 | 881 | 0.530 | 0.0575 | Yes |
| 9 | Mthfd2l | 903 | 0.523 | 0.0680 | Yes |
| 10 | Psma3 | 905 | 0.523 | 0.0802 | Yes |
| 11 | Rab1a | 939 | 0.516 | 0.0895 | Yes |
| 12 | Pno1 | 957 | 0.512 | 0.1001 | Yes |
| 13 | Ykt6 | 1082 | 0.486 | 0.1013 | Yes |
| 14 | Psph | 1107 | 0.480 | 0.1105 | Yes |
| 15 | Sec11a | 1180 | 0.467 | 0.1155 | Yes |
| 16 | Slc6a6 | 1270 | 0.456 | 0.1189 | Yes |
| 17 | Rrm2 | 1435 | 0.431 | 0.1155 | Yes |
| 18 | Eef1e1 | 1477 | 0.426 | 0.1221 | Yes |
| 19 | Slc2a1 | 1672 | 0.399 | 0.1155 | Yes |
| 20 | Psmd12 | 1692 | 0.397 | 0.1232 | Yes |
| 21 | Phgdh | 1703 | 0.396 | 0.1316 | Yes |
| 22 | Hmgcs1 | 1833 | 0.376 | 0.1298 | Yes |
| 23 | Tbk1 | 1869 | 0.372 | 0.1356 | Yes |
| 24 | Hspd1 | 1899 | 0.368 | 0.1418 | Yes |
| 25 | Cacybp | 1992 | 0.355 | 0.1426 | Yes |
| 26 | Sqstm1 | 1994 | 0.355 | 0.1508 | Yes |
| 27 | Mthfd2 | 2157 | 0.336 | 0.1453 | Yes |
| 28 | Ccng1 | 2158 | 0.336 | 0.1532 | Yes |
| 29 | Skap2 | 2210 | 0.329 | 0.1567 | Yes |
| 30 | Psmd13 | 2316 | 0.317 | 0.1555 | Yes |
| 31 | Psmc4 | 2378 | 0.311 | 0.1577 | Yes |
| 32 | Ssr1 | 2511 | 0.294 | 0.1538 | Yes |
| 33 | Me1 | 2548 | 0.290 | 0.1576 | Yes |
| 34 | Ddit3 | 2568 | 0.289 | 0.1628 | Yes |
| 35 | Cct6a | 2605 | 0.285 | 0.1665 | Yes |
| 36 | Hk2 | 2701 | 0.276 | 0.1651 | Yes |
| 37 | Psmd14 | 2745 | 0.271 | 0.1679 | Yes |
| 38 | Tubg1 | 2792 | 0.267 | 0.1704 | Yes |
| 39 | Ppp1r15a | 2886 | 0.257 | 0.1688 | Yes |
| 40 | Rpa1 | 2903 | 0.256 | 0.1734 | Yes |
| 41 | Acly | 2937 | 0.253 | 0.1766 | Yes |
| 42 | Aurka | 3182 | 0.230 | 0.1620 | No |
| 43 | Srd5a1 | 3218 | 0.227 | 0.1644 | No |
| 44 | Gclc | 3225 | 0.226 | 0.1692 | No |
| 45 | Ube2d3 | 3281 | 0.223 | 0.1699 | No |
| 46 | Hspa9 | 3313 | 0.219 | 0.1725 | No |
| 47 | Ero1a | 3414 | 0.212 | 0.1692 | No |
| 48 | Abcf2 | 3540 | 0.201 | 0.1636 | No |
| 49 | Ppia | 3750 | 0.183 | 0.1508 | No |
| 50 | Itgb2 | 3851 | 0.176 | 0.1467 | No |
| 51 | Gga2 | 3960 | 0.167 | 0.1417 | No |
| 52 | Etf1 | 4004 | 0.163 | 0.1420 | No |
| 53 | Elovl6 | 4087 | 0.156 | 0.1389 | No |
| 54 | Psmc6 | 4112 | 0.154 | 0.1405 | No |
| 55 | Ddx39a | 4125 | 0.153 | 0.1431 | No |
| 56 | Fgl2 | 4230 | 0.145 | 0.1380 | No |
| 57 | Ppa1 | 4278 | 0.141 | 0.1374 | No |
| 58 | Sla | 4313 | 0.138 | 0.1378 | No |
| 59 | Gsk3b | 4363 | 0.133 | 0.1369 | No |
| 60 | Hspe1 | 4378 | 0.132 | 0.1389 | No |
| 61 | Cd9 | 4388 | 0.131 | 0.1412 | No |
| 62 | Arpc5l | 4404 | 0.131 | 0.1430 | No |
| 63 | Rrp9 | 4408 | 0.130 | 0.1458 | No |
| 64 | Mcm2 | 4449 | 0.128 | 0.1455 | No |
| 65 | Got1 | 4531 | 0.123 | 0.1417 | No |
| 66 | Coro1a | 4603 | 0.117 | 0.1386 | No |
| 67 | Pitpnb | 4729 | 0.107 | 0.1309 | No |
| 68 | Psmb5 | 4841 | 0.100 | 0.1241 | No |
| 69 | Ctsc | 4912 | 0.097 | 0.1206 | No |
| 70 | Ldlr | 5004 | 0.090 | 0.1153 | No |
| 71 | Slc7a5 | 5025 | 0.087 | 0.1157 | No |
| 72 | Cyb5b | 5184 | 0.077 | 0.1045 | No |
| 73 | Psat1 | 5207 | 0.075 | 0.1045 | No |
| 74 | Niban1 | 5221 | 0.074 | 0.1052 | No |
| 75 | Egln3 | 5228 | 0.074 | 0.1064 | No |
| 76 | Wars1 | 5323 | 0.068 | 0.1003 | No |
| 77 | Nufip1 | 5440 | 0.059 | 0.0921 | No |
| 78 | Bub1 | 5459 | 0.058 | 0.0920 | No |
| 79 | Uso1 | 5616 | 0.048 | 0.0803 | No |
| 80 | Pnp | 5652 | 0.046 | 0.0785 | No |
| 81 | Fads2 | 5717 | 0.041 | 0.0743 | No |
| 82 | Tes | 5767 | 0.038 | 0.0711 | No |
| 83 | Ccnf | 5823 | 0.034 | 0.0674 | No |
| 84 | Acaca | 5899 | 0.027 | 0.0619 | No |
| 85 | Actr3 | 5912 | 0.026 | 0.0615 | No |
| 86 | Pdk1 | 5930 | 0.024 | 0.0606 | No |
| 87 | Txnrd1 | 6003 | 0.020 | 0.0552 | No |
| 88 | Ebp | 6027 | 0.018 | 0.0537 | No |
| 89 | Cyp51 | 6031 | 0.018 | 0.0539 | No |
| 90 | Pdap1 | 6148 | 0.009 | 0.0446 | No |
| 91 | Atp6v1d | 6219 | 0.005 | 0.0390 | No |
| 92 | Mllt11 | 6281 | 0.000 | 0.0340 | No |
| 93 | Ak4 | 6306 | -0.000 | 0.0320 | No |
| 94 | Cdc25a | 6366 | -0.005 | 0.0273 | No |
| 95 | Plod2 | 6413 | -0.008 | 0.0237 | No |
| 96 | Eif2s2 | 6581 | -0.018 | 0.0104 | No |
| 97 | Nmt1 | 6675 | -0.023 | 0.0033 | No |
| 98 | Psmg1 | 6708 | -0.026 | 0.0013 | No |
| 99 | Rpn1 | 6777 | -0.031 | -0.0036 | No |
| 100 | Psme3 | 6786 | -0.031 | -0.0035 | No |
| 101 | Hspa5 | 6839 | -0.036 | -0.0069 | No |
| 102 | Lta4h | 6842 | -0.036 | -0.0063 | No |
| 103 | Dhfr | 6875 | -0.039 | -0.0080 | No |
| 104 | Actr2 | 7022 | -0.047 | -0.0188 | No |
| 105 | Gpi1 | 7048 | -0.049 | -0.0197 | No |
| 106 | Fdxr | 7069 | -0.051 | -0.0202 | No |
| 107 | Serp1 | 7089 | -0.052 | -0.0205 | No |
| 108 | Cops5 | 7108 | -0.054 | -0.0207 | No |
| 109 | Polr3g | 7118 | -0.054 | -0.0202 | No |
| 110 | Asns | 7218 | -0.061 | -0.0269 | No |
| 111 | Canx | 7338 | -0.070 | -0.0350 | No |
| 112 | P4ha1 | 7339 | -0.070 | -0.0334 | No |
| 113 | Mcm4 | 7446 | -0.077 | -0.0403 | No |
| 114 | Hspa4 | 7495 | -0.079 | -0.0424 | No |
| 115 | Pgk1 | 7497 | -0.079 | -0.0407 | No |
| 116 | Uchl5 | 7530 | -0.081 | -0.0414 | No |
| 117 | Dapp1 | 7722 | -0.096 | -0.0548 | No |
| 118 | Calr | 7745 | -0.098 | -0.0543 | No |
| 119 | Cfp | 7915 | -0.110 | -0.0656 | No |
| 120 | Glrx | 7965 | -0.112 | -0.0670 | No |
| 121 | Hsp90b1 | 8052 | -0.118 | -0.0713 | No |
| 122 | Sc5d | 8141 | -0.125 | -0.0756 | No |
| 123 | Tpi1 | 8179 | -0.127 | -0.0757 | No |
| 124 | Gmps | 8210 | -0.129 | -0.0751 | No |
| 125 | Ddit4 | 8415 | -0.143 | -0.0885 | No |
| 126 | Tfrc | 8518 | -0.150 | -0.0934 | No |
| 127 | Map2k3 | 8631 | -0.157 | -0.0989 | No |
| 128 | M6pr | 8719 | -0.163 | -0.1022 | No |
| 129 | Hmgcr | 8742 | -0.165 | -0.1002 | No |
| 130 | Psma4 | 8753 | -0.166 | -0.0971 | No |
| 131 | Dhcr24 | 9047 | -0.189 | -0.1167 | No |
| 132 | Shmt2 | 9260 | -0.203 | -0.1294 | No |
| 133 | Ldha | 9618 | -0.234 | -0.1532 | No |
| 134 | Elovl5 | 9656 | -0.237 | -0.1507 | No |
| 135 | Vldlr | 9670 | -0.238 | -0.1462 | No |
| 136 | Qdpr | 9679 | -0.239 | -0.1413 | No |
| 137 | Nfkbib | 9755 | -0.245 | -0.1417 | No |
| 138 | Pfkl | 9824 | -0.249 | -0.1415 | No |
| 139 | Cxcr4 | 9867 | -0.253 | -0.1390 | No |
| 140 | Pgm1 | 9890 | -0.255 | -0.1349 | No |
| 141 | Fads1 | 9949 | -0.259 | -0.1336 | No |
| 142 | Aldoa | 10161 | -0.277 | -0.1444 | No |
| 143 | Nup205 | 10234 | -0.283 | -0.1437 | No |
| 144 | Slc1a5 | 10282 | -0.288 | -0.1409 | No |
| 145 | Ifrd1 | 10539 | -0.314 | -0.1545 | No |
| 146 | Hmbs | 10596 | -0.321 | -0.1516 | No |
| 147 | Fkbp2 | 10606 | -0.322 | -0.1449 | No |
| 148 | Psmc2 | 10657 | -0.326 | -0.1413 | No |
| 149 | Gbe1 | 10685 | -0.330 | -0.1359 | No |
| 150 | Nampt | 10840 | -0.350 | -0.1403 | No |
| 151 | Trib3 | 10864 | -0.353 | -0.1340 | No |
| 152 | Immt | 10891 | -0.356 | -0.1278 | No |
| 153 | Gsr | 10963 | -0.363 | -0.1251 | No |
| 154 | Slc2a3 | 10971 | -0.364 | -0.1172 | No |
| 155 | Add3 | 10989 | -0.367 | -0.1100 | No |
| 156 | Edem1 | 11003 | -0.369 | -0.1025 | No |
| 157 | Sord | 11317 | -0.415 | -0.1185 | No |
| 158 | Rdh11 | 11508 | -0.448 | -0.1236 | No |
| 159 | Ufm1 | 11518 | -0.450 | -0.1138 | No |
| 160 | Tuba4a | 11522 | -0.451 | -0.1036 | No |
| 161 | Acsl3 | 11532 | -0.452 | -0.0937 | No |
| 162 | Sqle | 11600 | -0.466 | -0.0884 | No |
| 163 | Xbp1 | 11618 | -0.470 | -0.0788 | No |
| 164 | Bhlhe40 | 11637 | -0.472 | -0.0692 | No |
| 165 | Adipor2 | 11683 | -0.482 | -0.0617 | No |
| 166 | Tcea1 | 11693 | -0.483 | -0.0511 | No |
| 167 | Stip1 | 11969 | -0.570 | -0.0604 | No |
| 168 | Prdx1 | 12029 | -0.594 | -0.0514 | No |
| 169 | Serpinh1 | 12066 | -0.612 | -0.0400 | No |
| 170 | G6pdx | 12116 | -0.639 | -0.0291 | No |
| 171 | Idh1 | 12130 | -0.650 | -0.0150 | No |
| 172 | Nupr1 | 12134 | -0.652 | -0.0001 | No |
| 173 | Atp2a2 | 12279 | -0.804 | 0.0069 | No |

