| Dataset | HSC.HSC_Pheno.cls#Group1_versus_Group2.HSC_Pheno.cls#Group1_versus_Group2_repos |
| Phenotype | HSC_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.27089754 |
| Normalized Enrichment Score (NES) | 0.90278137 |
| Nominal p-value | 0.6640777 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Gspt1 | 184 | 0.809 | 0.0035 | Yes |
| 2 | Dek | 280 | 0.732 | 0.0125 | Yes |
| 3 | Chek1 | 287 | 0.729 | 0.0288 | Yes |
| 4 | Shmt1 | 312 | 0.714 | 0.0432 | Yes |
| 5 | Pnn | 330 | 0.705 | 0.0580 | Yes |
| 6 | Rad51ap1 | 390 | 0.675 | 0.0687 | Yes |
| 7 | Cdca8 | 636 | 0.594 | 0.0623 | Yes |
| 8 | Spc25 | 647 | 0.592 | 0.0750 | Yes |
| 9 | Pold2 | 654 | 0.590 | 0.0881 | Yes |
| 10 | Trip13 | 696 | 0.579 | 0.0980 | Yes |
| 11 | Ube2t | 700 | 0.576 | 0.1110 | Yes |
| 12 | Smc4 | 726 | 0.570 | 0.1221 | Yes |
| 13 | Wee1 | 730 | 0.570 | 0.1349 | Yes |
| 14 | Pold1 | 879 | 0.531 | 0.1350 | Yes |
| 15 | Ssrp1 | 917 | 0.521 | 0.1439 | Yes |
| 16 | Eif2s1 | 1043 | 0.492 | 0.1450 | Yes |
| 17 | Pms2 | 1101 | 0.481 | 0.1514 | Yes |
| 18 | Ppp1r8 | 1179 | 0.467 | 0.1558 | Yes |
| 19 | Depdc1a | 1225 | 0.462 | 0.1627 | Yes |
| 20 | Pola2 | 1285 | 0.453 | 0.1683 | Yes |
| 21 | Orc2 | 1368 | 0.442 | 0.1717 | Yes |
| 22 | Cks2 | 1374 | 0.441 | 0.1815 | Yes |
| 23 | Rrm2 | 1435 | 0.431 | 0.1864 | Yes |
| 24 | Pds5b | 1438 | 0.430 | 0.1961 | Yes |
| 25 | Ube2s | 1577 | 0.411 | 0.1943 | Yes |
| 26 | Brca2 | 1607 | 0.408 | 0.2013 | Yes |
| 27 | Bard1 | 1748 | 0.388 | 0.1987 | Yes |
| 28 | Kif18b | 1763 | 0.385 | 0.2064 | Yes |
| 29 | Donson | 1827 | 0.377 | 0.2099 | Yes |
| 30 | Mcm5 | 1870 | 0.372 | 0.2150 | Yes |
| 31 | Prim2 | 1917 | 0.365 | 0.2196 | Yes |
| 32 | Mki67 | 1937 | 0.362 | 0.2264 | Yes |
| 33 | Mre11a | 1962 | 0.360 | 0.2327 | Yes |
| 34 | Ppm1d | 1965 | 0.360 | 0.2408 | Yes |
| 35 | Rfc2 | 1968 | 0.359 | 0.2489 | Yes |
| 36 | Cit | 1978 | 0.358 | 0.2563 | Yes |
| 37 | Xpo1 | 2031 | 0.350 | 0.2601 | Yes |
| 38 | Nbn | 2132 | 0.340 | 0.2597 | Yes |
| 39 | Mthfd2 | 2157 | 0.336 | 0.2655 | Yes |
| 40 | Mad2l1 | 2241 | 0.325 | 0.2661 | Yes |
| 41 | Atad2 | 2274 | 0.321 | 0.2709 | Yes |
| 42 | Pttg1 | 2469 | 0.301 | 0.2619 | No |
| 43 | Tk1 | 2472 | 0.300 | 0.2686 | No |
| 44 | Plk4 | 2659 | 0.279 | 0.2598 | No |
| 45 | Srsf2 | 2777 | 0.268 | 0.2563 | No |
| 46 | Tubg1 | 2792 | 0.267 | 0.2613 | No |
| 47 | Top2a | 2850 | 0.261 | 0.2626 | No |
| 48 | Rpa1 | 2903 | 0.256 | 0.2642 | No |
| 49 | Ccnb2 | 3139 | 0.233 | 0.2503 | No |
| 50 | Tmpo | 3168 | 0.231 | 0.2533 | No |
| 51 | Aurka | 3182 | 0.230 | 0.2575 | No |
| 52 | Cenpm | 3267 | 0.224 | 0.2558 | No |
| 53 | H2ax | 3358 | 0.217 | 0.2534 | No |
| 54 | Rad50 | 3488 | 0.205 | 0.2475 | No |
| 55 | Slbp | 3522 | 0.203 | 0.2495 | No |
| 56 | Dut | 3547 | 0.200 | 0.2521 | No |
| 57 | Hmgb3 | 3571 | 0.198 | 0.2547 | No |
| 58 | Racgap1 | 3584 | 0.196 | 0.2583 | No |
| 59 | Cnot9 | 3604 | 0.195 | 0.2612 | No |
| 60 | Hmmr | 3661 | 0.190 | 0.2609 | No |
| 61 | Rad1 | 3690 | 0.187 | 0.2629 | No |
| 62 | Kif4 | 3811 | 0.179 | 0.2572 | No |
| 63 | Pole4 | 3854 | 0.176 | 0.2578 | No |
| 64 | Lbr | 3934 | 0.169 | 0.2552 | No |
| 65 | E2f8 | 3965 | 0.167 | 0.2566 | No |
| 66 | Ddx39a | 4125 | 0.153 | 0.2470 | No |
| 67 | Hells | 4197 | 0.147 | 0.2446 | No |
| 68 | Rpa2 | 4210 | 0.146 | 0.2469 | No |
| 69 | Ncapd2 | 4297 | 0.139 | 0.2431 | No |
| 70 | Orc6 | 4314 | 0.138 | 0.2449 | No |
| 71 | Phf5a | 4315 | 0.138 | 0.2481 | No |
| 72 | Rad21 | 4320 | 0.137 | 0.2509 | No |
| 73 | Trp53 | 4401 | 0.131 | 0.2474 | No |
| 74 | Ran | 4414 | 0.130 | 0.2494 | No |
| 75 | Mcm2 | 4449 | 0.128 | 0.2495 | No |
| 76 | Spag5 | 4499 | 0.124 | 0.2483 | No |
| 77 | Ranbp1 | 4557 | 0.120 | 0.2464 | No |
| 78 | Timeless | 4558 | 0.120 | 0.2492 | No |
| 79 | Cdkn2c | 4630 | 0.115 | 0.2460 | No |
| 80 | Ezh2 | 4664 | 0.112 | 0.2459 | No |
| 81 | Gins4 | 4731 | 0.107 | 0.2429 | No |
| 82 | Prkdc | 4742 | 0.106 | 0.2446 | No |
| 83 | Smc3 | 4754 | 0.106 | 0.2461 | No |
| 84 | Pan2 | 4832 | 0.101 | 0.2421 | No |
| 85 | Cdk4 | 4856 | 0.100 | 0.2425 | No |
| 86 | Cenpe | 4862 | 0.099 | 0.2444 | No |
| 87 | Nolc1 | 5094 | 0.083 | 0.2273 | No |
| 88 | Psip1 | 5197 | 0.076 | 0.2207 | No |
| 89 | Ctcf | 5263 | 0.072 | 0.2170 | No |
| 90 | Cdc20 | 5311 | 0.069 | 0.2147 | No |
| 91 | Wdr90 | 5469 | 0.057 | 0.2032 | No |
| 92 | Tbrg4 | 5517 | 0.054 | 0.2006 | No |
| 93 | Dck | 5519 | 0.054 | 0.2017 | No |
| 94 | Cdkn1b | 5586 | 0.050 | 0.1975 | No |
| 95 | Stag1 | 5651 | 0.046 | 0.1933 | No |
| 96 | Nup107 | 5719 | 0.041 | 0.1887 | No |
| 97 | Tubb5 | 5768 | 0.038 | 0.1856 | No |
| 98 | Dclre1b | 5886 | 0.027 | 0.1767 | No |
| 99 | Nasp | 5934 | 0.024 | 0.1734 | No |
| 100 | Bub1b | 6002 | 0.020 | 0.1683 | No |
| 101 | Dctpp1 | 6029 | 0.018 | 0.1666 | No |
| 102 | Cdk1 | 6042 | 0.017 | 0.1660 | No |
| 103 | Prps1 | 6068 | 0.015 | 0.1643 | No |
| 104 | Cdc25a | 6366 | -0.005 | 0.1400 | No |
| 105 | Rpa3 | 6421 | -0.008 | 0.1358 | No |
| 106 | Jpt1 | 6478 | -0.011 | 0.1314 | No |
| 107 | Rnaseh2a | 6501 | -0.013 | 0.1299 | No |
| 108 | Ilf3 | 6579 | -0.018 | 0.1240 | No |
| 109 | Cdc25b | 6770 | -0.030 | 0.1091 | No |
| 110 | Diaph3 | 6890 | -0.040 | 0.1003 | No |
| 111 | Mcm7 | 6915 | -0.041 | 0.0992 | No |
| 112 | Exosc8 | 6939 | -0.043 | 0.0983 | No |
| 113 | Dlgap5 | 7010 | -0.047 | 0.0937 | No |
| 114 | Suv39h1 | 7024 | -0.048 | 0.0937 | No |
| 115 | Brca1 | 7036 | -0.048 | 0.0939 | No |
| 116 | Hnrnpd | 7092 | -0.053 | 0.0906 | No |
| 117 | Smc6 | 7181 | -0.059 | 0.0847 | No |
| 118 | Pole | 7277 | -0.065 | 0.0784 | No |
| 119 | Myc | 7363 | -0.071 | 0.0731 | No |
| 120 | Mybl2 | 7415 | -0.074 | 0.0706 | No |
| 121 | Mcm4 | 7446 | -0.077 | 0.0699 | No |
| 122 | Nap1l1 | 7582 | -0.086 | 0.0608 | No |
| 123 | Tra2b | 7669 | -0.093 | 0.0559 | No |
| 124 | Cse1l | 7852 | -0.105 | 0.0433 | No |
| 125 | Ing3 | 8006 | -0.115 | 0.0334 | No |
| 126 | Mms22l | 8018 | -0.116 | 0.0352 | No |
| 127 | Paics | 8078 | -0.120 | 0.0331 | No |
| 128 | Xrcc6 | 8100 | -0.122 | 0.0342 | No |
| 129 | Chek2 | 8125 | -0.123 | 0.0350 | No |
| 130 | Syncrip | 8131 | -0.124 | 0.0375 | No |
| 131 | Mlh1 | 8296 | -0.135 | 0.0271 | No |
| 132 | Anp32e | 8359 | -0.140 | 0.0252 | No |
| 133 | Pold3 | 8384 | -0.142 | 0.0265 | No |
| 134 | Ccp110 | 8423 | -0.144 | 0.0267 | No |
| 135 | Tfrc | 8518 | -0.150 | 0.0225 | No |
| 136 | Lyar | 8615 | -0.156 | 0.0182 | No |
| 137 | Lig1 | 8706 | -0.162 | 0.0145 | No |
| 138 | Gins3 | 8708 | -0.162 | 0.0182 | No |
| 139 | Ipo7 | 8892 | -0.177 | 0.0072 | No |
| 140 | Nop56 | 8915 | -0.179 | 0.0095 | No |
| 141 | Gins1 | 8992 | -0.185 | 0.0075 | No |
| 142 | Lsm8 | 9123 | -0.194 | 0.0013 | No |
| 143 | Cbx5 | 9140 | -0.195 | 0.0045 | No |
| 144 | Pa2g4 | 9194 | -0.199 | 0.0047 | No |
| 145 | Prdx4 | 9264 | -0.204 | 0.0037 | No |
| 146 | Pcna | 9320 | -0.209 | 0.0040 | No |
| 147 | Luc7l3 | 9575 | -0.230 | -0.0116 | No |
| 148 | H2az1 | 9663 | -0.238 | -0.0132 | No |
| 149 | Tacc3 | 9671 | -0.238 | -0.0083 | No |
| 150 | Nudt21 | 9751 | -0.244 | -0.0092 | No |
| 151 | Dscc1 | 9789 | -0.247 | -0.0065 | No |
| 152 | Dnmt1 | 9844 | -0.251 | -0.0052 | No |
| 153 | Mcm6 | 9847 | -0.251 | 0.0004 | No |
| 154 | Zw10 | 9852 | -0.251 | 0.0058 | No |
| 155 | Nup153 | 9883 | -0.254 | 0.0092 | No |
| 156 | Brms1l | 10126 | -0.273 | -0.0044 | No |
| 157 | Srsf1 | 10169 | -0.278 | -0.0015 | No |
| 158 | Ccne1 | 10195 | -0.280 | 0.0029 | No |
| 159 | Hmgb2 | 10207 | -0.280 | 0.0084 | No |
| 160 | Nup205 | 10234 | -0.283 | 0.0128 | No |
| 161 | Rfc3 | 10307 | -0.291 | 0.0136 | No |
| 162 | Rbbp7 | 10387 | -0.299 | 0.0140 | No |
| 163 | Ak2 | 10390 | -0.299 | 0.0207 | No |
| 164 | Birc5 | 10440 | -0.305 | 0.0236 | No |
| 165 | Tipin | 10550 | -0.316 | 0.0220 | No |
| 166 | Smc1a | 10582 | -0.319 | 0.0267 | No |
| 167 | Mcm3 | 10586 | -0.320 | 0.0339 | No |
| 168 | Usp1 | 10695 | -0.331 | 0.0326 | No |
| 169 | Ubr7 | 10721 | -0.334 | 0.0382 | No |
| 170 | Lmnb1 | 10771 | -0.341 | 0.0420 | No |
| 171 | Psmc3ip | 10828 | -0.348 | 0.0455 | No |
| 172 | Hus1 | 10839 | -0.350 | 0.0527 | No |
| 173 | Nme1 | 10868 | -0.354 | 0.0585 | No |
| 174 | Snrpb | 10915 | -0.358 | 0.0630 | No |
| 175 | Asf1a | 10918 | -0.358 | 0.0710 | No |
| 176 | Rfc1 | 11379 | -0.426 | 0.0431 | No |
| 177 | Eed | 11634 | -0.472 | 0.0331 | No |
| 178 | Stmn1 | 11871 | -0.536 | 0.0260 | No |
| 179 | Msh2 | 12087 | -0.622 | 0.0227 | No |

