| Dataset | GMP.GMP.neu_Pheno.cls #Group6_versus_Group8.GMP.neu_Pheno.cls #Group6_versus_Group8_repos |
| Phenotype | GMP.neu_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | -0.32798746 |
| Normalized Enrichment Score (NES) | -1.4094381 |
| Nominal p-value | 0.100409836 |
| FDR q-value | 0.17515105 |
| FWER p-Value | 0.553 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Plk1 | 420 | 0.689 | -0.0056 | No |
| 2 | Pik3r3 | 436 | 0.680 | 0.0090 | No |
| 3 | Gbe1 | 737 | 0.601 | 0.0074 | No |
| 4 | Asns | 955 | 0.552 | 0.0090 | No |
| 5 | Bhlhe40 | 1136 | 0.524 | 0.0117 | No |
| 6 | Sytl2 | 1208 | 0.515 | 0.0198 | No |
| 7 | Ero1a | 1218 | 0.515 | 0.0310 | No |
| 8 | Sla | 1260 | 0.507 | 0.0404 | No |
| 9 | Gsr | 1362 | 0.495 | 0.0464 | No |
| 10 | Arpc5l | 1376 | 0.494 | 0.0569 | No |
| 11 | Nupr1 | 1597 | 0.468 | 0.0564 | No |
| 12 | Btg2 | 1729 | 0.457 | 0.0602 | No |
| 13 | Slc7a11 | 2421 | 0.381 | 0.0339 | No |
| 14 | Itgb2 | 2578 | 0.371 | 0.0344 | No |
| 15 | Cxcr4 | 2750 | 0.360 | 0.0339 | No |
| 16 | Gga2 | 2806 | 0.356 | 0.0392 | No |
| 17 | Fdxr | 3104 | 0.339 | 0.0319 | No |
| 18 | Aurka | 3547 | 0.309 | 0.0166 | No |
| 19 | Tm7sf2 | 3692 | 0.299 | 0.0161 | No |
| 20 | Glrx | 3734 | 0.296 | 0.0207 | No |
| 21 | Ccnf | 3776 | 0.292 | 0.0252 | No |
| 22 | Lta4h | 3873 | 0.283 | 0.0268 | No |
| 23 | Pgm1 | 4085 | 0.267 | 0.0221 | No |
| 24 | Trib3 | 4109 | 0.266 | 0.0270 | No |
| 25 | Psmd14 | 4254 | 0.257 | 0.0256 | No |
| 26 | Niban1 | 4471 | 0.244 | 0.0202 | No |
| 27 | Tfrc | 4969 | 0.217 | 0.0000 | No |
| 28 | Psph | 5058 | 0.211 | 0.0003 | No |
| 29 | Elovl5 | 5180 | 0.204 | -0.0012 | No |
| 30 | Abcf2 | 5496 | 0.194 | -0.0127 | No |
| 31 | Ykt6 | 5730 | 0.186 | -0.0202 | No |
| 32 | Cyb5b | 5906 | 0.176 | -0.0250 | No |
| 33 | Add3 | 6024 | 0.171 | -0.0271 | No |
| 34 | Gla | 6220 | 0.166 | -0.0332 | No |
| 35 | Phgdh | 6237 | 0.165 | -0.0302 | No |
| 36 | Slc1a5 | 6325 | 0.161 | -0.0310 | No |
| 37 | Ppp1r15a | 7148 | 0.122 | -0.0697 | No |
| 38 | Cdc25a | 7167 | 0.121 | -0.0678 | No |
| 39 | Atp6v1d | 7188 | 0.120 | -0.0661 | No |
| 40 | Hmbs | 7217 | 0.119 | -0.0649 | No |
| 41 | Ldlr | 7290 | 0.115 | -0.0659 | No |
| 42 | Gsk3b | 7333 | 0.113 | -0.0655 | No |
| 43 | Actr3 | 7380 | 0.111 | -0.0653 | No |
| 44 | Sdf2l1 | 7546 | 0.104 | -0.0712 | No |
| 45 | Srd5a1 | 7572 | 0.102 | -0.0702 | No |
| 46 | Xbp1 | 7709 | 0.097 | -0.0749 | No |
| 47 | Nup205 | 7817 | 0.092 | -0.0782 | No |
| 48 | Coro1a | 7835 | 0.091 | -0.0770 | No |
| 49 | Sqle | 8021 | 0.084 | -0.0844 | No |
| 50 | Tmem97 | 8120 | 0.080 | -0.0875 | No |
| 51 | Rrp9 | 8412 | 0.068 | -0.1007 | No |
| 52 | Atp2a2 | 8609 | 0.060 | -0.1092 | No |
| 53 | Slc2a1 | 8677 | 0.058 | -0.1113 | No |
| 54 | Gtf2h1 | 8718 | 0.056 | -0.1120 | No |
| 55 | Psmc2 | 8741 | 0.055 | -0.1119 | No |
| 56 | Cd9 | 8849 | 0.051 | -0.1161 | No |
| 57 | Edem1 | 8917 | 0.048 | -0.1184 | No |
| 58 | Nfyc | 8988 | 0.045 | -0.1209 | No |
| 59 | Gclc | 9199 | 0.037 | -0.1306 | No |
| 60 | Acaca | 9272 | 0.034 | -0.1335 | No |
| 61 | Map2k3 | 9278 | 0.034 | -0.1330 | No |
| 62 | Slc6a6 | 9292 | 0.033 | -0.1329 | No |
| 63 | Ddit3 | 9346 | 0.030 | -0.1349 | No |
| 64 | Hmgcs1 | 9363 | 0.030 | -0.1350 | No |
| 65 | Nampt | 9366 | 0.030 | -0.1345 | No |
| 66 | Ifrd1 | 9406 | 0.028 | -0.1358 | No |
| 67 | Nmt1 | 9421 | 0.027 | -0.1359 | No |
| 68 | Cth | 9440 | 0.027 | -0.1362 | No |
| 69 | Acly | 9548 | 0.023 | -0.1411 | No |
| 70 | Pitpnb | 9637 | 0.019 | -0.1451 | No |
| 71 | Skap2 | 9657 | 0.018 | -0.1456 | No |
| 72 | Slc37a4 | 9681 | 0.017 | -0.1464 | No |
| 73 | Actr2 | 10485 | -0.007 | -0.1867 | No |
| 74 | Psmc4 | 10515 | -0.008 | -0.1880 | No |
| 75 | G6pdx | 10794 | -0.017 | -0.2017 | No |
| 76 | Tbk1 | 10806 | -0.017 | -0.2018 | No |
| 77 | Etf1 | 10907 | -0.021 | -0.2064 | No |
| 78 | Sord | 10933 | -0.022 | -0.2071 | No |
| 79 | Dhcr24 | 10936 | -0.022 | -0.2067 | No |
| 80 | Cfp | 10981 | -0.024 | -0.2084 | No |
| 81 | Hmgcr | 10982 | -0.024 | -0.2079 | No |
| 82 | Gpi1 | 10990 | -0.025 | -0.2076 | No |
| 83 | Dhcr7 | 11009 | -0.025 | -0.2080 | No |
| 84 | Fkbp2 | 11080 | -0.029 | -0.2109 | No |
| 85 | Slc7a5 | 11095 | -0.029 | -0.2109 | No |
| 86 | Hk2 | 11160 | -0.031 | -0.2134 | No |
| 87 | Rit1 | 11274 | -0.036 | -0.2183 | No |
| 88 | Bub1 | 11394 | -0.041 | -0.2234 | No |
| 89 | Sec11a | 11731 | -0.054 | -0.2391 | No |
| 90 | Pfkl | 11733 | -0.055 | -0.2379 | No |
| 91 | Hsp90b1 | 11794 | -0.057 | -0.2396 | No |
| 92 | Cops5 | 11890 | -0.061 | -0.2431 | No |
| 93 | Eno1b | 12014 | -0.067 | -0.2477 | No |
| 94 | Tomm40 | 12052 | -0.068 | -0.2481 | No |
| 95 | Wars1 | 12106 | -0.071 | -0.2491 | No |
| 96 | P4ha1 | 12156 | -0.073 | -0.2499 | No |
| 97 | Insig1 | 12221 | -0.076 | -0.2515 | No |
| 98 | Sc5d | 12264 | -0.078 | -0.2518 | No |
| 99 | Psmd12 | 12290 | -0.079 | -0.2513 | No |
| 100 | Ufm1 | 12335 | -0.081 | -0.2517 | No |
| 101 | Stard4 | 12383 | -0.083 | -0.2522 | No |
| 102 | Uso1 | 12425 | -0.085 | -0.2523 | No |
| 103 | Tcea1 | 12510 | -0.089 | -0.2545 | No |
| 104 | Idi1 | 12619 | -0.094 | -0.2579 | No |
| 105 | Fgl2 | 12684 | -0.096 | -0.2589 | No |
| 106 | Immt | 12771 | -0.100 | -0.2610 | No |
| 107 | Ssr1 | 12937 | -0.107 | -0.2669 | No |
| 108 | Psma3 | 12965 | -0.107 | -0.2658 | No |
| 109 | Ddit4 | 12977 | -0.108 | -0.2639 | No |
| 110 | Aldoa | 13127 | -0.114 | -0.2689 | No |
| 111 | Nfil3 | 13130 | -0.114 | -0.2664 | No |
| 112 | Pnp | 13258 | -0.120 | -0.2701 | No |
| 113 | Gmps | 13359 | -0.124 | -0.2723 | No |
| 114 | Rrm2 | 13677 | -0.138 | -0.2852 | No |
| 115 | M6pr | 13967 | -0.149 | -0.2964 | No |
| 116 | Cyp51 | 13990 | -0.150 | -0.2941 | No |
| 117 | Polr3g | 14006 | -0.151 | -0.2914 | No |
| 118 | Dhfr | 14047 | -0.153 | -0.2900 | No |
| 119 | Ube2d3 | 14119 | -0.157 | -0.2900 | No |
| 120 | Psmd13 | 14314 | -0.164 | -0.2961 | No |
| 121 | Psme3 | 14338 | -0.166 | -0.2935 | No |
| 122 | Ccng1 | 14405 | -0.168 | -0.2930 | No |
| 123 | Tubg1 | 14580 | -0.177 | -0.2978 | No |
| 124 | Idh1 | 14657 | -0.180 | -0.2976 | No |
| 125 | Hspa5 | 14674 | -0.181 | -0.2943 | No |
| 126 | Hspa4 | 14724 | -0.184 | -0.2926 | No |
| 127 | Psat1 | 14853 | -0.190 | -0.2948 | No |
| 128 | Fads2 | 14924 | -0.193 | -0.2939 | No |
| 129 | Sqstm1 | 15111 | -0.202 | -0.2987 | No |
| 130 | Acsl3 | 15275 | -0.210 | -0.3022 | No |
| 131 | Slc1a4 | 15455 | -0.219 | -0.3063 | No |
| 132 | Txnrd1 | 15768 | -0.233 | -0.3168 | No |
| 133 | Mllt11 | 15891 | -0.240 | -0.3175 | No |
| 134 | Mthfd2l | 16014 | -0.247 | -0.3181 | No |
| 135 | Psmc6 | 16062 | -0.250 | -0.3148 | No |
| 136 | Vldlr | 16325 | -0.262 | -0.3221 | Yes |
| 137 | Canx | 16380 | -0.265 | -0.3188 | Yes |
| 138 | Me1 | 16460 | -0.270 | -0.3167 | Yes |
| 139 | Nfkbib | 16483 | -0.272 | -0.3116 | Yes |
| 140 | Uchl5 | 16503 | -0.273 | -0.3064 | Yes |
| 141 | Cacybp | 16595 | -0.276 | -0.3048 | Yes |
| 142 | Adipor2 | 16819 | -0.291 | -0.3094 | Yes |
| 143 | Eif2s2 | 16865 | -0.294 | -0.3051 | Yes |
| 144 | Pdap1 | 16873 | -0.295 | -0.2988 | Yes |
| 145 | Mcm2 | 16992 | -0.302 | -0.2979 | Yes |
| 146 | Cdkn1a | 17015 | -0.304 | -0.2921 | Yes |
| 147 | Rpn1 | 17138 | -0.313 | -0.2912 | Yes |
| 148 | Shmt2 | 17153 | -0.314 | -0.2848 | Yes |
| 149 | Hspe1 | 17180 | -0.315 | -0.2790 | Yes |
| 150 | Ebp | 17225 | -0.318 | -0.2741 | Yes |
| 151 | Slc2a3 | 17228 | -0.319 | -0.2670 | Yes |
| 152 | Rpa1 | 17269 | -0.321 | -0.2617 | Yes |
| 153 | Tes | 17290 | -0.322 | -0.2555 | Yes |
| 154 | Eef1e1 | 17295 | -0.322 | -0.2484 | Yes |
| 155 | Serp1 | 17340 | -0.325 | -0.2433 | Yes |
| 156 | Psmg1 | 17348 | -0.325 | -0.2363 | Yes |
| 157 | Lgmn | 17397 | -0.328 | -0.2313 | Yes |
| 158 | Psmb5 | 17451 | -0.331 | -0.2265 | Yes |
| 159 | Hspa9 | 17456 | -0.332 | -0.2192 | Yes |
| 160 | Pgk1 | 17541 | -0.337 | -0.2158 | Yes |
| 161 | Stip1 | 17568 | -0.338 | -0.2095 | Yes |
| 162 | Ppa1 | 17693 | -0.347 | -0.2079 | Yes |
| 163 | Mcm4 | 17703 | -0.348 | -0.2005 | Yes |
| 164 | Ddx39a | 17715 | -0.349 | -0.1931 | Yes |
| 165 | Plod2 | 17779 | -0.354 | -0.1883 | Yes |
| 166 | Elovl6 | 17804 | -0.357 | -0.1815 | Yes |
| 167 | Cct6a | 17809 | -0.357 | -0.1736 | Yes |
| 168 | Ppia | 17951 | -0.370 | -0.1723 | Yes |
| 169 | Hspd1 | 18035 | -0.376 | -0.1680 | Yes |
| 170 | Calr | 18096 | -0.381 | -0.1624 | Yes |
| 171 | Psma4 | 18124 | -0.384 | -0.1551 | Yes |
| 172 | Qdpr | 18137 | -0.385 | -0.1470 | Yes |
| 173 | Ak4 | 18187 | -0.389 | -0.1407 | Yes |
| 174 | Rab1a | 18229 | -0.393 | -0.1339 | Yes |
| 175 | Ctsc | 18306 | -0.400 | -0.1287 | Yes |
| 176 | Dapp1 | 18343 | -0.403 | -0.1214 | Yes |
| 177 | Tuba4a | 18490 | -0.418 | -0.1193 | Yes |
| 178 | Egln3 | 18610 | -0.431 | -0.1156 | Yes |
| 179 | Rdh11 | 19005 | -0.486 | -0.1245 | Yes |
| 180 | Pdk1 | 19043 | -0.493 | -0.1152 | Yes |
| 181 | Fads1 | 19128 | -0.509 | -0.1080 | Yes |
| 182 | Ldha | 19167 | -0.518 | -0.0982 | Yes |
| 183 | Got1 | 19359 | -0.557 | -0.0952 | Yes |
| 184 | Tpi1 | 19523 | -0.605 | -0.0898 | Yes |
| 185 | Nufip1 | 19544 | -0.613 | -0.0770 | Yes |
| 186 | Mthfd2 | 19559 | -0.618 | -0.0637 | Yes |
| 187 | Pno1 | 19684 | -0.670 | -0.0548 | Yes |
| 188 | Prdx1 | 19776 | -0.718 | -0.0432 | Yes |
| 189 | Bcat1 | 19853 | -0.764 | -0.0298 | Yes |
| 190 | Ung | 19892 | -0.795 | -0.0137 | Yes |
| 191 | Ifi30 | 19969 | -0.904 | 0.0029 | Yes |

