Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GMP.GMP.neu_Pheno.cls #Group3_versus_Group4.GMP.neu_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | GMP.neu_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_TGF_BETA_SIGNALING |
| Enrichment Score (ES) | -0.17182595 |
| Normalized Enrichment Score (NES) | -0.7879251 |
| Nominal p-value | 0.77096117 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.999 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Smad7 | 1307 | 0.460 | -0.0169 | Yes |
| 2 | Ski | 1450 | 0.446 | 0.0231 | Yes |
| 3 | Id2 | 1794 | 0.413 | 0.0495 | Yes |
| 4 | Ppm1a | 2080 | 0.384 | 0.0757 | Yes |
| 5 | Cdh1 | 2170 | 0.373 | 0.1106 | Yes |
| 6 | Wwtr1 | 2322 | 0.362 | 0.1413 | Yes |
| 7 | Rhoa | 3089 | 0.312 | 0.1359 | Yes |
| 8 | Smad6 | 3349 | 0.296 | 0.1542 | Yes |
| 9 | Furin | 3618 | 0.280 | 0.1704 | Yes |
| 10 | Fnta | 4653 | 0.224 | 0.1423 | No |
| 11 | Klf10 | 4793 | 0.215 | 0.1580 | No |
| 12 | Id1 | 5097 | 0.201 | 0.1640 | No |
| 13 | Rab31 | 5613 | 0.178 | 0.1571 | No |
| 14 | Acvr1 | 6539 | 0.135 | 0.1250 | No |
| 15 | Bmpr1a | 6796 | 0.124 | 0.1252 | No |
| 16 | Skil | 6915 | 0.119 | 0.1319 | No |
| 17 | Ltbp2 | 6927 | 0.119 | 0.1439 | No |
| 18 | Ppp1r15a | 7835 | 0.090 | 0.1080 | No |
| 19 | Ncor2 | 8200 | 0.076 | 0.0978 | No |
| 20 | Fkbp1a | 8561 | 0.061 | 0.0862 | No |
| 21 | Bmpr2 | 9066 | 0.041 | 0.0653 | No |
| 22 | Smad1 | 9087 | 0.040 | 0.0686 | No |
| 23 | Sptbn1 | 9189 | 0.036 | 0.0673 | No |
| 24 | Tgfbr1 | 9386 | 0.030 | 0.0607 | No |
| 25 | Eng | 9496 | 0.027 | 0.0581 | No |
| 26 | Tgfb1 | 11199 | -0.025 | -0.0244 | No |
| 27 | Junb | 11249 | -0.027 | -0.0240 | No |
| 28 | Xiap | 11337 | -0.031 | -0.0251 | No |
| 29 | Smurf2 | 11936 | -0.052 | -0.0496 | No |
| 30 | Hipk2 | 12114 | -0.056 | -0.0525 | No |
| 31 | Apc | 12430 | -0.067 | -0.0612 | No |
| 32 | Trim33 | 12456 | -0.068 | -0.0552 | No |
| 33 | Cdk9 | 12844 | -0.082 | -0.0659 | No |
| 34 | Ifngr2 | 13038 | -0.090 | -0.0661 | No |
| 35 | Ppp1ca | 13402 | -0.102 | -0.0735 | No |
| 36 | Map3k7 | 13793 | -0.117 | -0.0806 | No |
| 37 | Tjp1 | 13837 | -0.118 | -0.0703 | No |
| 38 | Smad3 | 14353 | -0.140 | -0.0813 | No |
| 39 | Smurf1 | 14490 | -0.145 | -0.0729 | No |
| 40 | Cdkn1c | 15364 | -0.182 | -0.0974 | No |
| 41 | Arid4b | 16042 | -0.211 | -0.1090 | No |
| 42 | Ube2d3 | 16245 | -0.219 | -0.0960 | No |
| 43 | Ctnnb1 | 16330 | -0.223 | -0.0767 | No |
| 44 | Thbs1 | 18231 | -0.339 | -0.1361 | No |
| 45 | Slc20a1 | 18358 | -0.349 | -0.1056 | No |
| 46 | Hdac1 | 18737 | -0.391 | -0.0833 | No |
| 47 | Bcar3 | 18815 | -0.400 | -0.0449 | No |
| 48 | Tgif1 | 19292 | -0.463 | -0.0198 | No |
| 49 | Pmepa1 | 19595 | -0.535 | 0.0216 | No |
