| Dataset | GMP.GMP.neu_Pheno.cls #Group3_versus_Group4.GMP.neu_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | GMP.neu_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_P53_PATHWAY |
| Enrichment Score (ES) | -0.17704485 |
| Normalized Enrichment Score (NES) | -0.7859867 |
| Nominal p-value | 0.88271606 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.999 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Tchh | 69 | 0.916 | 0.0217 | No |
| 2 | Rgs16 | 366 | 0.660 | 0.0250 | No |
| 3 | H2ac25 | 396 | 0.646 | 0.0413 | No |
| 4 | Tpd52l1 | 405 | 0.643 | 0.0586 | No |
| 5 | Cd81 | 504 | 0.608 | 0.0703 | No |
| 6 | Sdc1 | 558 | 0.594 | 0.0840 | No |
| 7 | Abhd4 | 567 | 0.591 | 0.0999 | No |
| 8 | Rrp8 | 570 | 0.590 | 0.1160 | No |
| 9 | Ralgds | 605 | 0.580 | 0.1302 | No |
| 10 | Fas | 622 | 0.577 | 0.1453 | No |
| 11 | Ada | 1271 | 0.466 | 0.1254 | No |
| 12 | Pmm1 | 1791 | 0.413 | 0.1107 | No |
| 13 | Klk8 | 1832 | 0.409 | 0.1199 | No |
| 14 | Ctsd | 2002 | 0.393 | 0.1222 | No |
| 15 | Jag2 | 2113 | 0.380 | 0.1271 | No |
| 16 | Ccnd2 | 2531 | 0.349 | 0.1157 | No |
| 17 | Txnip | 2672 | 0.339 | 0.1179 | No |
| 18 | Fos | 2798 | 0.330 | 0.1207 | No |
| 19 | Rps12 | 3392 | 0.294 | 0.0989 | No |
| 20 | Btg2 | 3450 | 0.292 | 0.1041 | No |
| 21 | Nupr1 | 3569 | 0.284 | 0.1060 | No |
| 22 | Coq8a | 3690 | 0.275 | 0.1075 | No |
| 23 | Xpc | 3792 | 0.268 | 0.1098 | No |
| 24 | Ldhb | 3846 | 0.263 | 0.1143 | No |
| 25 | Pvt1 | 3904 | 0.260 | 0.1186 | No |
| 26 | Trib3 | 3953 | 0.257 | 0.1233 | No |
| 27 | F2r | 4254 | 0.242 | 0.1148 | No |
| 28 | Wwp1 | 4318 | 0.237 | 0.1182 | No |
| 29 | Vamp8 | 4553 | 0.228 | 0.1126 | No |
| 30 | Stom | 4576 | 0.227 | 0.1178 | No |
| 31 | Def6 | 4674 | 0.223 | 0.1190 | No |
| 32 | Vdr | 4716 | 0.220 | 0.1230 | No |
| 33 | Rxra | 4798 | 0.215 | 0.1248 | No |
| 34 | H1f2 | 5163 | 0.197 | 0.1119 | No |
| 35 | Ankra2 | 5177 | 0.196 | 0.1167 | No |
| 36 | Fuca1 | 5241 | 0.194 | 0.1188 | No |
| 37 | Ier5 | 5307 | 0.190 | 0.1208 | No |
| 38 | Klf4 | 5415 | 0.184 | 0.1205 | No |
| 39 | Ddit4 | 5693 | 0.174 | 0.1113 | No |
| 40 | App | 5775 | 0.170 | 0.1119 | No |
| 41 | Cdh13 | 5869 | 0.166 | 0.1118 | No |
| 42 | Ip6k2 | 6174 | 0.152 | 0.1006 | No |
| 43 | Ifi30 | 6187 | 0.151 | 0.1042 | No |
| 44 | Cyfip2 | 6497 | 0.137 | 0.0924 | No |
| 45 | Zbtb16 | 6689 | 0.128 | 0.0863 | No |
| 46 | Socs1 | 6786 | 0.124 | 0.0849 | No |
| 47 | Cd82 | 6812 | 0.123 | 0.0870 | No |
| 48 | Rap2b | 6882 | 0.121 | 0.0868 | No |
| 49 | Rack1 | 7193 | 0.115 | 0.0744 | No |
| 50 | Tm7sf3 | 7400 | 0.107 | 0.0670 | No |
| 51 | Ccng1 | 7402 | 0.107 | 0.0699 | No |
| 52 | Hras | 7432 | 0.106 | 0.0713 | No |
| 53 | Mknk2 | 7492 | 0.103 | 0.0712 | No |
| 54 | Rnf19b | 7547 | 0.101 | 0.0712 | No |
| 55 | Nudt15 | 7673 | 0.097 | 0.0676 | No |
| 56 | Prmt2 | 7760 | 0.093 | 0.0658 | No |
| 57 | Irak1 | 7812 | 0.091 | 0.0658 | No |
| 58 | Ppp1r15a | 7835 | 0.090 | 0.0671 | No |
| 59 | Tap1 | 7843 | 0.089 | 0.0692 | No |
| 60 | Osgin1 | 7935 | 0.086 | 0.0670 | No |
| 61 | Perp | 8345 | 0.070 | 0.0483 | No |
| 62 | Abcc5 | 8509 | 0.063 | 0.0419 | No |
| 63 | Dcxr | 8560 | 0.061 | 0.0410 | No |
| 64 | Tprkb | 8656 | 0.057 | 0.0378 | No |
| 65 | Tax1bp3 | 8730 | 0.054 | 0.0356 | No |
| 66 | Itgb4 | 8769 | 0.053 | 0.0351 | No |
| 67 | Jun | 8945 | 0.046 | 0.0276 | No |
| 68 | Fam162a | 8957 | 0.046 | 0.0283 | No |
| 69 | Hspa4l | 8982 | 0.045 | 0.0283 | No |
| 70 | Traf4 | 9018 | 0.043 | 0.0277 | No |
| 71 | Pdgfa | 9089 | 0.040 | 0.0253 | No |
| 72 | Steap3 | 9164 | 0.037 | 0.0226 | No |
| 73 | S100a4 | 9208 | 0.036 | 0.0214 | No |
| 74 | Fdxr | 9339 | 0.032 | 0.0158 | No |
| 75 | Blcap | 9371 | 0.031 | 0.0151 | No |
| 76 | Bak1 | 9388 | 0.030 | 0.0151 | No |
| 77 | Zmat3 | 9390 | 0.030 | 0.0159 | No |
| 78 | Fbxw7 | 9513 | 0.026 | 0.0104 | No |
| 79 | Sp1 | 9697 | 0.019 | 0.0017 | No |
| 80 | Tob1 | 9803 | 0.015 | -0.0031 | No |
| 81 | Ppm1d | 9839 | 0.014 | -0.0045 | No |
| 82 | Mxd4 | 9924 | 0.012 | -0.0084 | No |
| 83 | Baiap2 | 9988 | 0.010 | -0.0113 | No |
| 84 | Ccp110 | 10091 | 0.006 | -0.0163 | No |
| 85 | Ei24 | 10166 | 0.003 | -0.0200 | No |
| 86 | Alox8 | 10262 | 0.000 | -0.0248 | No |
| 87 | Dgka | 10590 | -0.005 | -0.0411 | No |
| 88 | Pitpnc1 | 10788 | -0.012 | -0.0507 | No |
| 89 | Vwa5a | 10958 | -0.018 | -0.0587 | No |
| 90 | Rchy1 | 11006 | -0.019 | -0.0606 | No |
| 91 | Foxo3 | 11016 | -0.020 | -0.0605 | No |
| 92 | Tgfb1 | 11199 | -0.025 | -0.0690 | No |
| 93 | Retsat | 11286 | -0.029 | -0.0725 | No |
| 94 | Mdm2 | 11295 | -0.029 | -0.0721 | No |
| 95 | Irag2 | 11422 | -0.034 | -0.0775 | No |
| 96 | Ptpre | 11477 | -0.035 | -0.0793 | No |
| 97 | Rps27l | 11548 | -0.038 | -0.0818 | No |
| 98 | Zfp36l1 | 11557 | -0.038 | -0.0811 | No |
| 99 | Rab40c | 11560 | -0.038 | -0.0802 | No |
| 100 | Trafd1 | 11775 | -0.046 | -0.0897 | No |
| 101 | Slc7a11 | 11934 | -0.051 | -0.0962 | No |
| 102 | Triap1 | 11978 | -0.053 | -0.0969 | No |
| 103 | Pcna | 12050 | -0.054 | -0.0990 | No |
| 104 | Bax | 12054 | -0.054 | -0.0977 | No |
| 105 | Rrad | 12059 | -0.054 | -0.0964 | No |
| 106 | Apaf1 | 12087 | -0.055 | -0.0963 | No |
| 107 | Mapkapk3 | 12090 | -0.055 | -0.0948 | No |
| 108 | Ninj1 | 12328 | -0.064 | -0.1050 | No |
| 109 | Notch1 | 12345 | -0.064 | -0.1041 | No |
| 110 | Slc3a2 | 12394 | -0.066 | -0.1047 | No |
| 111 | Slc35d1 | 12396 | -0.066 | -0.1029 | No |
| 112 | Hexim1 | 12545 | -0.072 | -0.1084 | No |
| 113 | Tsc22d1 | 12595 | -0.073 | -0.1088 | No |
| 114 | Rhbdf2 | 12660 | -0.076 | -0.1100 | No |
| 115 | Hbegf | 12734 | -0.079 | -0.1115 | No |
| 116 | Cdkn2aip | 12750 | -0.079 | -0.1100 | No |
| 117 | Hdac3 | 12783 | -0.081 | -0.1094 | No |
| 118 | Dnttip2 | 12850 | -0.083 | -0.1105 | No |
| 119 | Pidd1 | 12889 | -0.085 | -0.1101 | No |
| 120 | Rb1 | 13093 | -0.091 | -0.1178 | No |
| 121 | Prkab1 | 13117 | -0.092 | -0.1164 | No |
| 122 | Abat | 13139 | -0.093 | -0.1149 | No |
| 123 | Sfn | 13237 | -0.096 | -0.1171 | No |
| 124 | Polh | 13564 | -0.108 | -0.1306 | No |
| 125 | St14 | 13582 | -0.109 | -0.1285 | No |
| 126 | Elp1 | 13642 | -0.111 | -0.1284 | No |
| 127 | Ercc5 | 13803 | -0.118 | -0.1332 | No |
| 128 | Ptpn14 | 13868 | -0.119 | -0.1332 | No |
| 129 | Trp53 | 13969 | -0.123 | -0.1348 | No |
| 130 | Rad51c | 14061 | -0.128 | -0.1359 | No |
| 131 | Hint1 | 14176 | -0.132 | -0.1380 | No |
| 132 | Gm2a | 14194 | -0.133 | -0.1352 | No |
| 133 | Cdk5r1 | 14375 | -0.140 | -0.1404 | No |
| 134 | Ddit3 | 14640 | -0.151 | -0.1495 | No |
| 135 | Kif13b | 15187 | -0.174 | -0.1723 | Yes |
| 136 | Ier3 | 15206 | -0.175 | -0.1684 | Yes |
| 137 | Rpl36 | 15207 | -0.175 | -0.1636 | Yes |
| 138 | Cgrrf1 | 15254 | -0.178 | -0.1610 | Yes |
| 139 | Ccnk | 15451 | -0.182 | -0.1659 | Yes |
| 140 | Ddb2 | 15475 | -0.183 | -0.1620 | Yes |
| 141 | Csrnp2 | 15519 | -0.185 | -0.1591 | Yes |
| 142 | Cebpa | 15628 | -0.190 | -0.1593 | Yes |
| 143 | Ndrg1 | 15680 | -0.192 | -0.1566 | Yes |
| 144 | Aen | 15792 | -0.198 | -0.1567 | Yes |
| 145 | Rad9a | 15799 | -0.199 | -0.1515 | Yes |
| 146 | Ccnd3 | 15939 | -0.206 | -0.1529 | Yes |
| 147 | Sertad3 | 15966 | -0.207 | -0.1485 | Yes |
| 148 | Nol8 | 15982 | -0.208 | -0.1435 | Yes |
| 149 | Mxd1 | 16146 | -0.213 | -0.1459 | Yes |
| 150 | Pom121 | 16166 | -0.215 | -0.1409 | Yes |
| 151 | Ctsf | 16175 | -0.215 | -0.1354 | Yes |
| 152 | Sec61a1 | 16624 | -0.240 | -0.1514 | Yes |
| 153 | Gadd45a | 16675 | -0.243 | -0.1473 | Yes |
| 154 | Sesn1 | 16691 | -0.244 | -0.1413 | Yes |
| 155 | Plxnb2 | 16744 | -0.247 | -0.1371 | Yes |
| 156 | Trp63 | 16913 | -0.257 | -0.1385 | Yes |
| 157 | Casp1 | 16957 | -0.260 | -0.1335 | Yes |
| 158 | Tspyl2 | 17130 | -0.269 | -0.1348 | Yes |
| 159 | Tcn2 | 17390 | -0.281 | -0.1401 | Yes |
| 160 | Rpl18 | 17430 | -0.284 | -0.1343 | Yes |
| 161 | S100a10 | 17474 | -0.288 | -0.1285 | Yes |
| 162 | Ak1 | 17533 | -0.292 | -0.1234 | Yes |
| 163 | Tnfsf9 | 17541 | -0.292 | -0.1157 | Yes |
| 164 | Sat1 | 17793 | -0.310 | -0.1198 | Yes |
| 165 | Eps8l2 | 17952 | -0.320 | -0.1190 | Yes |
| 166 | Hmox1 | 18169 | -0.335 | -0.1207 | Yes |
| 167 | Plk2 | 18209 | -0.337 | -0.1134 | Yes |
| 168 | H2aj | 18236 | -0.339 | -0.1053 | Yes |
| 169 | Wrap73 | 18376 | -0.350 | -0.1027 | Yes |
| 170 | Dram1 | 18553 | -0.368 | -0.1014 | Yes |
| 171 | Slc19a2 | 18578 | -0.371 | -0.0924 | Yes |
| 172 | Acvr1b | 18790 | -0.397 | -0.0921 | Yes |
| 173 | Sphk1 | 18909 | -0.411 | -0.0868 | Yes |
| 174 | Iscu | 18949 | -0.417 | -0.0773 | Yes |
| 175 | Atf3 | 19027 | -0.424 | -0.0695 | Yes |
| 176 | Fgf13 | 19053 | -0.428 | -0.0590 | Yes |
| 177 | Tgfa | 19158 | -0.441 | -0.0521 | Yes |
| 178 | Plk3 | 19312 | -0.468 | -0.0469 | Yes |
| 179 | Cdkn1a | 19498 | -0.508 | -0.0423 | Yes |
| 180 | Procr | 19642 | -0.550 | -0.0344 | Yes |
| 181 | Btg1 | 19684 | -0.564 | -0.0209 | Yes |
| 182 | Ephx1 | 19750 | -0.587 | -0.0080 | Yes |
| 183 | Gls2 | 19971 | -0.796 | 0.0028 | Yes |

